Details for: CLCA2

Gene ID: 9635

Symbol: CLCA2

Ensembl ID: ENSG00000137975

Description: chloride channel accessory 2

Associated with

Other Information

Genular Protein ID: 2452376446

Symbol: CLCA2_HUMAN

Name: Calcium-activated chloride channel regulator 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10362588

Title: Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland.

PubMed ID: 10362588

DOI: 10.1152/ajpcell.1999.276.6.c1261

PubMed ID: 10437792

Title: Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.

PubMed ID: 10437792

DOI: 10.1016/s0014-5793(99)00891-1

PubMed ID: 11262615

Title: Isolation and characterization of a Ca(2+)-activated chloride channel from human corneal epithelium.

PubMed ID: 11262615

DOI: 10.1076/ceyr.21.6.918.6983

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10554024

Title: Tumorigenicity of human breast cancer is associated with loss of the Ca2+-activated chloride channel CLCA2.

PubMed ID: 10554024

PubMed ID: 11445004

Title: Expression of the Ca2+-activated chloride channel genes CLCA1 and CLCA2 is downregulated in human colorectal cancer.

PubMed ID: 11445004

DOI: 10.1089/10445490152122442

PubMed ID: 11320086

Title: The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis.

PubMed ID: 11320086

DOI: 10.1074/jbc.m100478200

PubMed ID: 14966209

Title: Calcium-activated chloride channel-2 in human epithelia.

PubMed ID: 14966209

DOI: 10.1177/002215540405200313

PubMed ID: 15707651

Title: The quantification of hCLCA2 and colocalisation with integrin beta4 in stratified human epithelia.

PubMed ID: 15707651

DOI: 10.1016/j.acthis.2004.08.003

PubMed ID: 16158324

Title: Gene expression and immunolocalisation of a calcium-activated chloride channel during the stratification of cultivated and developing corneal epithelium.

PubMed ID: 16158324

DOI: 10.1007/s00441-005-0059-2

PubMed ID: 16873362

Title: The putative chloride channel hCLCA2 has a single C-terminal transmembrane segment.

PubMed ID: 16873362

DOI: 10.1074/jbc.m605919200

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 943
  • Mass: 103941
  • Checksum: 0E09A09090D2529B
  • Sequence:
  • MTQRSIAGPI CNLKFVTLLV ALSSELPFLG AGVQLQDNGY NGLLIAINPQ VPENQNLISN 
    IKEMITEASF YLFNATKRRV FFRNIKILIP ATWKANNNSK IKQESYEKAN VIVTDWYGAH 
    GDDPYTLQYR GCGKEGKYIH FTPNFLLNDN LTAGYGSRGR VFVHEWAHLR WGVFDEYNND 
    KPFYINGQNQ IKVTRCSSDI TGIFVCEKGP CPQENCIISK LFKEGCTFIY NSTQNATASI 
    MFMQSLSSVV EFCNASTHNQ EAPNLQNQMC SLRSAWDVIT DSADFHHSFP MNGTELPPPP 
    TFSLVQAGDK VVCLVLDVSS KMAEADRLLQ LQQAAEFYLM QIVEIHTFVG IASFDSKGEI 
    RAQLHQINSN DDRKLLVSYL PTTVSAKTDI SICSGLKKGF EVVEKLNGKA YGSVMILVTS 
    GDDKLLGNCL PTVLSSGSTI HSIALGSSAA PNLEELSRLT GGLKFFVPDI SNSNSMIDAF 
    SRISSGTGDI FQQHIQLEST GENVKPHHQL KNTVTVDNTV GNDTMFLVTW QASGPPEIIL 
    FDPDGRKYYT NNFITNLTFR TASLWIPGTA KPGHWTYTLN NTHHSLQALK VTVTSRASNS 
    AVPPATVEAF VERDSLHFPH PVMIYANVKQ GFYPILNATV TATVEPETGD PVTLRLLDDG 
    AGADVIKNDG IYSRYFFSFA ANGRYSLKVH VNHSPSISTP AHSIPGSHAM YVPGYTANGN 
    IQMNAPRKSV GRNEEERKWG FSRVSSGGSF SVLGVPAGPH PDVFPPCKII DLEAVKVEEE 
    LTLSWTAPGE DFDQGQATSY EIRMSKSLQN IQDDFNNAIL VNTSKRNPQQ AGIREIFTFS 
    PQISTNGPEH QPNGETHESH RIYVAIRAMD RNSLQSAVSN IAQAPLFIPP NSDPVPARDY 
    LILKGVLTAM GLIGIICLII VVTHHTLSRK KRADKKENGT KLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.