IQCB1 | ENSG00000173226 | NCBI 9657

Details for: IQCB1

Gene ID: 9657

Symbol: IQCB1

Ensembl ID: ENSG00000173226

Description: IQ motif containing B1

Associated with

Anchoring of the basal body to the plasma membrane
(R-HSA-5620912)
Organelle biogenesis and maintenance
(R-HSA-1852241)
Bbsome binding
(GO:0062063)
Calmodulin binding
(GO:0005516)
Centriole
(GO:0005814)
Centrosome
(GO:0005813)
Cilium
(GO:0005929)
Cilium assembly
(GO:0060271)
Cytosol
(GO:0005829)
Cytosolic ciliogenesis
(GO:0061824)
Enzyme binding
(GO:0019899)
Extracellular exosome
(GO:0070062)
Intercellular bridge
(GO:0045171)
Maintenance of animal organ identity
(GO:0048496)
Microtubule cytoskeleton
(GO:0015630)
Mitotic spindle
(GO:0072686)
Nucleoplasm
(GO:0005654)
Photoreceptor cell maintenance
(GO:0045494)
Photoreceptor connecting cilium
(GO:0032391)
Photoreceptor outer segment
(GO:0001750)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)

Other Information

Proteins

IQ calmodulin-binding motif-containing protein 1

Genular Protein ID: 627966291

Symbol: IQCB1_HUMAN

Name: IQ calmodulin-binding motif-containing protein 1

UniProtKB Accession Codes:

Q15051 Q3KS08 Q3KS09 Q5DKQ7 Q8NI79 Q9BS08

Database IDs:

Citations:

PubMed ID: 16322217

Title: Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers.

PubMed ID: 16322217

DOI: 10.1158/0008-5472.can-05-1132

PubMed ID: 15723066

Title: Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin.

PubMed ID: 15723066

DOI: 10.1038/ng1520

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18723859

Title: Genetic and physical interaction between the NPHP5 and NPHP6 gene products.

PubMed ID: 18723859

DOI: 10.1093/hmg/ddn260

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21565611

Title: Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

PubMed ID: 21565611

DOI: 10.1016/j.cell.2011.04.019

PubMed ID: 23446637

Title: Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis.

PubMed ID: 23446637

DOI: 10.1093/hmg/ddt100

PubMed ID: 25552655

Title: Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.

PubMed ID: 25552655

DOI: 10.1093/hmg/ddu738

Sequence Information:

Length: 598
Mass: 68929
Checksum: 5589FDE6B0D15D78
Sequence:

MKPTGTDPRI LSIAAEVAKS PEQNVPVILL KLKEIINITP LGSSELKKIK QDIYCYDLIQ 
YCLLVLSQDY SRIQGGWTTI SQLTQILSHC CVGLEPGEDA EEFYNELLPS AAENFLVLGR 
QLQTCFINAA KAEEKDELLH FFQIVTDSLF WLLGGHVELI QNVLQSDHFL HLLQADNVQI 
GSAVMMMLQN ILQINSGDLL RIGRKALYSI LDEVIFKLFS TPSPVIRSTA TKLLLLMAES 
HQEILILLRQ STCYKGLRRL LSKQETGTEF SQELRQLVGL LSPMVYQEVE EQKLHQAACL 
IQAYWKGFQT RKRLKKLPSA VIALQRSFRS KRSKMLLEIN RQKEEEDLKL QLQLQRQRAM 
RLSRELQLSM LEIVHPGQVE KHYREMEEKS ALIIQKHWRG YRERKNFHQQ RQSLIEYKAA 
VTLQRAALKF LAKCRKKKKL FAPWRGLQEL TDARRVELKK RVDDYVRRHL GSPMSDVVSR 
ELHAQAQERL QHYFMGRALE ERAQQHREAL IAQISTNVEQ LMKAPSLKEA EGKEPELFLS 
RSRPVAAKAK QAHLTTLKHI QAPWWKKLGE ESGDEIDVPK DELSIELENL FIGGTKPP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: IQCB1

Associated with

Other Information

Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers. PubMed ID: 16322217

Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. PubMed ID: 15723066

Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. PubMed ID: 7584026

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Genetic and physical interaction between the NPHP5 and NPHP6 gene products. PubMed ID: 18723859

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Initial characterization of the human central proteome. PubMed ID: 21269460

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. PubMed ID: 21565611

Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis. PubMed ID: 23446637

Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery. PubMed ID: 25552655