Details for: CEP135

Gene ID: 9662

Symbol: CEP135

Ensembl ID: ENSG00000174799

Description: centrosomal protein 135

Associated with

Other Information

Genular Protein ID: 735612841

Symbol: CP135_HUMAN

Name: Centrosomal protein 4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 17681131

Title: Plk4-induced centriole biogenesis in human cells.

PubMed ID: 17681131

DOI: 10.1016/j.devcel.2007.07.002

PubMed ID: 18851962

Title: A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.

PubMed ID: 18851962

DOI: 10.1016/j.yexcr.2008.09.016

PubMed ID: 22521416

Title: A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function.

PubMed ID: 22521416

DOI: 10.1016/j.ajhg.2012.03.016

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26675238

Title: WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis.

PubMed ID: 26675238

DOI: 10.1242/jcs.179713

PubMed ID: 27185865

Title: CEP295 interacts with microtubules and is required for centriole elongation.

PubMed ID: 27185865

DOI: 10.1242/jcs.186338

PubMed ID: 32060285

Title: CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.

PubMed ID: 32060285

DOI: 10.1038/s41467-020-14767-2

PubMed ID: 27477386

Title: The Human centriolar protein CEP135 contains a two-stranded coiled-coil domain critical for microtubule binding.

PubMed ID: 27477386

DOI: 10.1016/j.str.2016.06.011

PubMed ID: 30135143

Title: Combinatorial use of disulfide bridges and native sulfur-SAD phasing for rapid structure determination of coiled-coils.

PubMed ID: 30135143

DOI: 10.1042/bsr20181073

Sequence Information:

  • Length: 1140
  • Mass: 133490
  • Checksum: AD56754BEBB3AA5B
  • Sequence:
  • MTTAVERKYI NIRKRLDQLG YRQTLTVECL PLVEKLFSDL VHTTESLRQS KLSAVKAEKE 
    SANFDFVLEP YKLENARLSR ENNELYLELM KLREHSDQHV KELKTSLKKC ARETADLKFL 
    NNQYAHKLKL LEKESKAKNE RIQQLQEKNL HAVVQTPGGK KRSIAFRRQR MQIDEPVPPS 
    EVSSYPVPQP DDPYIADLLQ VADNRIQELQ QEVHQLQEKL AMMESGVRDY SKQIELRERE 
    IERLSVALDG GRSPDVLSLE SRNKTNEKLI AHLNIQVDFL QQANKDLEKR IRELMETKET 
    VTSEVVNLSN KNEKLCQELT EIDQLAQQLE RHKEEVLETA DKELGEAKKE IKRKLSEMQD 
    LEETMAKLQL ELNLCQKEKE RLSDELLVKS DLETVVHQLE QEKQRLSKKV ESFAVTERQL 
    TLEVERMRLE HGIKRRDRSP SRLDTFLKGI EEERDYYKKE LERLQHIIQR RSCSTSYSAR 
    EKSSIFRTPE KGDYNSEIHQ ITRERDELQR MLERFEKYME DIQSNVKLLT AERDKLSVLY 
    NEAQEELSAL RKESTQTTAP HNIVSLMEKE KELALSDLRR IMAEKEALRE KLEHIEEVSL 
    FGKSELEKTI EHLTCVNHQL ESEKYELKSK VLIMKETIES LENKLKVQAQ KFSHVAGDSS 
    HQKTEVNSLR IVNEQLQRSV DDYQHRLSIK RGELESAQAQ IKILEEKIDE LNLKMTSQDE 
    EAHVMKKTIG VIDKEKDFLQ ETVDEKTEKI ANLQENLANK EKAVAQMKIM ISECESSVNQ 
    LKETLVNRDR EINSLRRQLD AAHKELDEVG RSREIAFKEN RRLQDDLATM ARENQEISLE 
    LEAAVQEKEE MKSRVHKYIT EVSRWESLMA AKEKENQDLL DRFQMLHNRA EDWEVKAHQA 
    EGESSSVRLE LLSIDTERRH LRERVELLEK EIQEHINAHH AYESQISSMA KAMSRLEEEL 
    RHQEDEKATV LNDLSSLREL CIKLDSGKDI MTQQLNSKNL EFERVVVELE NVKSESDLLK 
    KQLSNERHTV KNLESLLATN RDKEFHSHLT SHEKDTEIQL LKEKLTLSES KLTSQSRENT 
    MLRAKVAQLQ TDYDALKRQI STERYERERA IQEMRRHGLA TPPLSSTLRS PSHSPEHRNV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.