CEP57 | ENSG00000166037 | NCBI 9702

Details for: CEP57

Gene ID: 9702

Symbol: CEP57

Ensembl ID: ENSG00000166037

Description: centrosomal protein 57

Associated with

Anchoring of the basal body to the plasma membrane
(R-HSA-5620912)
Aurka activation by tpx2
(R-HSA-8854518)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Centrosome maturation
(R-HSA-380287)
Cilium assembly
(R-HSA-5617833)
G2/m transition
(R-HSA-69275)
Loss of nlp from mitotic centrosomes
(R-HSA-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-HSA-380284)
Mitotic g2-g2/m phases
(R-HSA-453274)
Mitotic prometaphase
(R-HSA-68877)
M phase
(R-HSA-68886)
Organelle biogenesis and maintenance
(R-HSA-1852241)
Recruitment of mitotic centrosome proteins and complexes
(R-HSA-380270)
Recruitment of numa to mitotic centrosomes
(R-HSA-380320)
Regulation of plk1 activity at g2/m transition
(R-HSA-2565942)
Centriolar satellite
(GO:0034451)
Centrosome
(GO:0005813)
Cytosol
(GO:0005829)
Fibroblast growth factor binding
(GO:0017134)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Gamma-tubulin binding
(GO:0043015)
Golgi apparatus
(GO:0005794)
Microtubule
(GO:0005874)
Microtubule binding
(GO:0008017)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein homooligomerization
(GO:0051260)
Spermatid development
(GO:0007286)

Other Information

Proteins

Centrosomal protein of 57 kDa

Genular Protein ID: 2640895352

Symbol: CEP57_HUMAN

Name: Centrosomal protein of 57 kDa

UniProtKB Accession Codes:

Q86XR8 A0PJH1 A8K5D0 B4DDP5 F5H5F7 Q14704 Q5JB46 Q8IXP0 Q9BVF9

Database IDs:

Citations:

PubMed ID: 12717444

Title: Translokin is an intracellular mediator of FGF-2 trafficking.

PubMed ID: 12717444

DOI: 10.1038/ncb979

PubMed ID: 7788527

Title: Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7788527

DOI: 10.1093/dnares/2.1.37

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 21552266

Title: Mutations in CEP57 cause mosaic variegated aneuploidy syndrome.

PubMed ID: 21552266

DOI: 10.1038/ng.822

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22321063

Title: Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnalpha1 and Kpnbeta1.

PubMed ID: 22321063

DOI: 10.1111/j.1600-0854.2012.01341.x

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

Length: 500
Mass: 57089
Checksum: 88FC47E7B33CE328
Sequence:

MAAASVSAAS GSHLSNSFAE PSRSNGSMVR HSSSPYVVYP SDKPFLNSDL RRSPSKPTLA 
YPESNSRAIF SALKNLQDKI RRLELERIQA EESVKTLSRE TIEYKKVLDE QIQERENSKN 
EESKHNQELT SQLLAAENKC NLLEKQLEYM RNMIKHAEME RTSVLEKQVS LERERQHDQT 
HVQSQLEKLD LLEQEYNKLT TMQALAEKKM QELEAKLHEE EQERKRMQAK AAELQTGLET 
NRLIFEDKAT PCVPNARRIK KKKSKPPEKK SSRNYFGAQP HYRLCLGDMP FVAGKSTSPS 
HAVVANVQLV LHLMKQHSKA LCNDRVINSI PLAKQVSSRG GKSKKLSVTP PSSNGINEEL 
SEVLQTLQDE FGQMSFDHQQ LAKLIQESPT VELKDKLECE LEALVGRMEA KANQITKVRK 
YQAQLEKQKL EKQKKELKAT KKTLDEERNS SSRSGITGTT NKKDFMKLRP GEKRRKNLQL 
LKDMQSIQNS LQSSSLCWDY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CEP57

Associated with

Other Information

Translokin is an intracellular mediator of FGF-2 trafficking. PubMed ID: 12717444

Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. PubMed ID: 7788527

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Human chromosome 11 DNA sequence and analysis including novel gene identification. PubMed ID: 16554811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Proteomic characterization of the human centrosome by protein correlation profiling. PubMed ID: 14654843

Mutations in CEP57 cause mosaic variegated aneuploidy syndrome. PubMed ID: 21552266

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnalpha1 and Kpnbeta1. PubMed ID: 22321063

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163