Details for: RUBCN

Gene ID: 9711

Symbol: RUBCN

Ensembl ID: ENSG00000145016

Description: rubicon autophagy regulator

Associated with

Other Information

Genular Protein ID: 953997112

Symbol: RUBIC_HUMAN

Name: Beclin-1 associated RUN domain containing protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9039502

Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PubMed ID: 9039502

DOI: 10.1093/dnares/3.5.321

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19270696

Title: Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

PubMed ID: 19270696

DOI: 10.1038/ncb1846

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20826435

Title: Rundataxin, a novel protein with RUN and diacylglycerol binding domains, is mutant in a new recessive ataxia.

PubMed ID: 20826435

DOI: 10.1093/brain/awq181

PubMed ID: 20943950

Title: Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain.

PubMed ID: 20943950

DOI: 10.1091/mbc.e10-06-0495

PubMed ID: 20974968

Title: Rubicon controls endosome maturation as a Rab7 effector.

PubMed ID: 20974968

DOI: 10.1073/pnas.1010554107

PubMed ID: 21062745

Title: The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression.

PubMed ID: 21062745

DOI: 10.1074/jbc.m110.126425

PubMed ID: 22423966

Title: Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.

PubMed ID: 22423966

DOI: 10.1016/j.chom.2012.01.018

PubMed ID: 22423967

Title: The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity.

PubMed ID: 22423967

DOI: 10.1016/j.chom.2012.01.019

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

  • Length: 972
  • Mass: 108622
  • Checksum: 4B76166F29F5AF97
  • Sequence:
  • MRPEGAGMEL GGGEERLPEE SRREHWQLLG NLKTTVEGLV STNSPNVWSK YGGLERLCRD 
    MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA 
    VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP 
    RLLAQIDASM FARKHESPLL VTKSQSLTAL PSSTYTPPNS YAQHSYFGSF SSLHQSVPNN 
    GSERRSTSFP LSGPPRKPQE SRGHVSPAED QTIQAPPVSV SALARDSPLT PNEMSSSTLT 
    SPIEASWVSS QNDSPGDASE GPEYLAIGNL DPRGRTASCQ SHSSNAESSS SNLFSSSSSQ 
    KPDSAASSLG DQEGGGESQL SSVLRRSSFS EGQTLTVTSG AKKSHIRSHS DTSIASRGAP 
    ESCNDKAKLR GPLPYSGQSS EVSTPSSLYM EYEGGRYLCS GEGMFRRPSE GQSLISYLSE 
    QDFGSCADLE KENAHFSISE SLIAAIELMK CNMMSQCLEE EEVEEEDSDR EIQELKQKIR 
    LRRQQIRTKN LLPMYQEAEH GSFRVTSSSS QFSSRDSAQL SDSGSADEVD EFEIQDADIR 
    RNTASSSKSF VSSQSFSHCF LHSTSAEAVA MGLLKQFEGM QLPAASELEW LVPEHDAPQK 
    LLPIPDSLPI SPDDGQHADI YKLRIRVRGN LEWAPPRPQI IFNVHPAPTR KIAVAKQNYR 
    CAGCGIRTDP DYIKRLRYCE YLGKYFCQCC HENAQMAIPS RVLRKWDFSK YYVSNFSKDL 
    LIKIWNDPLF NVQDINSALY RKVKLLNQVR LLRVQLCHMK NMFKTCRLAK ELLDSFDTVP 
    GHLTEDLHLY SLNDLTATRK GELGPRLAEL TRAGATHVER CMLCQAKGFI CEFCQNEDDI 
    IFPFELHKCR TCEECKACYH KACFKSGSCP RCERLQARRE ALARQSLESY LSDYEEEPAE 
    ALALEAAVLE AT

Genular Protein ID: 3810433397

Symbol: Q8N4U6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 375
  • Mass: 40799
  • Checksum: 2DCED261B3CACFF3
  • Sequence:
  • MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA 
    VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP 
    RLLAQIDASM FARKHESPLL VTKSQSLTAL PSSTYTPPNS YAQHSYFGSF SSLHQSVPNN 
    GSERRSTSFP LSGPPRKPQE SRGHVSPAED QTIQAPPVSV SALARDSPLT PNEMSSSTLT 
    SPIEASWVSS QNDSPGDASE GPEYLAIGNL DPRGRTASCQ SHSSNAESSS SNLFSSSSSQ 
    KPDSAASSLG DQEGGGESQL SSVLRRSSFS EGQTLTVTSG AKKSHIRSHS DTSIASRGAP 
    GNEEHRLLVS KMTLN

Genular Protein ID: 1595871565

Symbol: A0A9L9PY84_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1011
  • Mass: 112560
  • Checksum: 8463418F17E76366
  • Sequence:
  • MRPEGAGMEL GGGEERLPEE SRREHWQLLG NLKTTVEGLV STNSPNVWSK YGGLERLCRD 
    MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA 
    VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP 
    RLLAQIDASM FARKHESPLL VTKSQSLTAL PSSTYTPPNS YAQHSYFGSF SSLHQSVPNN 
    GSERRSTSFP LSGPPRKPQE SRGHVSPAED QTIQAPPVSV SALARDSPLT PNEMSSSTLT 
    SPIEASWVSS QNDSPGDASE GPEYLAIGNL DPRGRTASCQ SHSSNAESSS SNLFSSSSSQ 
    KPDSAASSLG DQEGGGESQL SSVLRRSSFS EGQTLTVTSG AKKSHIRSHS DTSIASRGAP 
    GGPRNITIIV EDPIAESCND KAKLRGPLPY SGQSSEVSTP SSLYMEYGGR YLCSGEGMFR 
    RPSEGQSLIS YLSEQDFGSC ADLEKENAHF SISESLIAAI ELMKCNMMSQ CLEEEEVEEE 
    DSDREIQELK QKIRLRRQQI RTKNLLPMYQ EAEHGSFRVT SSSSQFSSRD SAQLSDSGSA 
    DEVDEFEIQD GSEGSNLTHI SKNGLSVSLA SMFSDADIRR NTASSSKSFV SSQSFSHCFL 
    HSTSAEAVAM GLLKQFEGMQ LPAASELEWL VPEHDAPQKL LPIPDSLPIS PDDGQHADIY 
    KLRIRVRGNL EWAPPRPQII FNVHPAPTRK IAVAKQNYRC AGCGIRTDPD YIKRLRYCEY 
    LGKYFCQCCH ENAQMAIPSR VLRKWDFSKY YVSNFSKDLL IKIWNDPLFN VQDINSALYR 
    KVKLLNQVRL LRVQLCHMKN MFKTCRLAKE LLDSFDTVPG HLTEDLHLYS LNDLTATRKG 
    ELGPRLAELT RAGATHVERC MLCQAKGFIC EFCQNEDDII FPFELHKCRT CEECKACYHK 
    ACFKSGSCPR CERLQARREA LARQSLESYL SDYEEEPAEA LALEAAVLEA T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.