RAB11FIP3 | ENSG00000090565 | NCBI 9727

Details for: RAB11FIP3

Gene ID: 9727

Symbol: RAB11FIP3

Ensembl ID: ENSG00000090565

Description: RAB11 family interacting protein 3

Associated with

Cargo trafficking to the periciliary membrane
(R-HSA-5620920)
Cilium assembly
(R-HSA-5617833)
Organelle biogenesis and maintenance
(R-HSA-1852241)
Vxpx cargo-targeting to cilium
(R-HSA-5620916)
Calcium ion binding
(GO:0005509)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Centriolar satellite
(GO:0034451)
Centrosome
(GO:0005813)
Cleavage furrow
(GO:0032154)
Cytosol
(GO:0005829)
Dynein light intermediate chain binding
(GO:0051959)
Endocytic recycling
(GO:0032456)
Endocytic vesicle
(GO:0030139)
Endocytic vesicle membrane
(GO:0030666)
Endosome
(GO:0005768)
Golgi membrane
(GO:0000139)
Identical protein binding
(GO:0042802)
Intercellular bridge
(GO:0045171)
Intracellular membrane-bounded organelle
(GO:0043231)
Midbody
(GO:0030496)
Mitochondrion
(GO:0005739)
Molecular adaptor activity
(GO:0060090)
Negative regulation of adiponectin secretion
(GO:0070164)
Nucleoplasm
(GO:0005654)
Postsynaptic recycling endosome membrane
(GO:0098944)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein localization to cilium
(GO:0061512)
Recycling endosome
(GO:0055037)
Recycling endosome membrane
(GO:0055038)
Regulation of cilium assembly
(GO:1902017)
Regulation of cytokinesis
(GO:0032465)
Regulation of early endosome to recycling endosome transport
(GO:1902954)
Regulation of endocytic recycling
(GO:2001135)
Regulation of protein localization to centrosome
(GO:1904779)
Regulation of vesicle-mediated transport
(GO:0060627)
Small gtpase binding
(GO:0031267)
Trans-golgi network membrane
(GO:0032588)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

MU-MB-17.148

Genular Protein ID: 4127677771

Symbol: RFIP3_HUMAN

Name: MU-MB-17.148

UniProtKB Accession Codes:

O75154 B0QYI8 B0QYT8 B1AHQ0 B4DEI7 B4DZR6 Q4VXV7 Q7Z5E9 Q9H155 Q9H1G0 Q9NUI0

Database IDs:

Citations:

PubMed ID: 11481332

Title: Identification of a novel Rab11/25 binding domain present in eferin and rip proteins.

PubMed ID: 11481332

DOI: 10.1074/jbc.m106133200

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11157797

Title: Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.

PubMed ID: 11157797

DOI: 10.1093/hmg/10.4.339

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12800201

Title: Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries.

PubMed ID: 12800201

DOI: 10.1002/ijc.11208

PubMed ID: 11495908

Title: Identification and characterization of a family of Rab11-interacting proteins.

PubMed ID: 11495908

DOI: 10.1074/jbc.m104831200

PubMed ID: 12470645

Title: Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

PubMed ID: 12470645

DOI: 10.1016/s0006-291x(02)02720-1

PubMed ID: 15158446

Title: Rab11-FIP3 localises to a Rab11-positive pericentrosomal compartment during interphase and to the cleavage furrow during cytokinesis.

PubMed ID: 15158446

DOI: 10.1016/j.bbrc.2004.04.157

PubMed ID: 16148947

Title: Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.

PubMed ID: 16148947

DOI: 10.1038/sj.emboj.7600803

PubMed ID: 15601896

Title: The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.

PubMed ID: 15601896

DOI: 10.1091/mbc.e04-10-0927

PubMed ID: 17628206

Title: Molecular characterization of Rab11-FIP3 binding to ARF GTPases.

PubMed ID: 17628206

DOI: 10.1016/j.ejcb.2007.05.004

PubMed ID: 17229837

Title: Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene.

PubMed ID: 17229837

DOI: 10.1073/pnas.0610500104

PubMed ID: 17394487

Title: Rab11-FIP3 is critical for the structural integrity of the endosomal recycling compartment.

PubMed ID: 17394487

DOI: 10.1111/j.1600-0854.2007.00543.x

PubMed ID: 18511905

Title: Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.

PubMed ID: 18511905

DOI: 10.1038/emboj.2008.112

PubMed ID: 19327867

Title: Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton.

PubMed ID: 19327867

DOI: 10.1016/j.ejcb.2009.02.186

PubMed ID: 20026645

Title: Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment.

PubMed ID: 20026645

DOI: 10.1242/jcs.052670

PubMed ID: 22401586

Title: Rab11-FIP3 is a cell cycle-regulated phosphoprotein.

PubMed ID: 22401586

DOI: 10.1186/1471-2121-13-4

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25035494

Title: Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes.

PubMed ID: 25035494

DOI: 10.1126/science.1254198

PubMed ID: 25673879

Title: The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting.

PubMed ID: 25673879

DOI: 10.1242/jcs.162925

PubMed ID: 31204173

Title: Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.

PubMed ID: 31204173

DOI: 10.1016/j.devcel.2019.05.022

PubMed ID: 17007872

Title: Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.

PubMed ID: 17007872

DOI: 10.1016/j.jmb.2006.08.064

PubMed ID: 17030804

Title: Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.

PubMed ID: 17030804

DOI: 10.1073/pnas.0605357103

PubMed ID: 26258637

Title: Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.

PubMed ID: 26258637

DOI: 10.1038/nsmb.3065

Sequence Information:

Length: 756
Mass: 82440
Checksum: 264CEC399F28AFB9
Sequence:

MASAPPASPP GSEPPGPDPE PGGPDGPGAA QLAPGPAELR LGAPVGGPDP QSPGLDEPAP 
GAAADGGARW SAGPAPGLEG GPRDPGPSAP PPRSGPRGQL ASPDAPGPGP RSEAPLPELD 
PLFSWTEEPE ECGPASCPES APFRLQGSSS SHRARGEVDV FSPFPAPTAG ELALEQGPGS 
PPQPSDLSQT HPLPSEPVGS QEDGPRLRAV FDALDGDGDG FVRIEDFIQF ATVYGAEQVK 
DLTKYLDPSG LGVISFEDFY QGITAIRNGD PDGQCYGGVA SAQDEEPLAC PDEFDDFVTY 
EANEVTDSAY MGSESTYSEC ETFTDEDTST LVHPELQPEG DADSAGGSAV PSECLDAMEE 
PDHGALLLLP GRPHPHGQSV ITVIGGEEHF EDYGEGSEAE LSPETLCNGQ LGCSDPAFLT 
PSPTKRLSSK KVARYLHQSG ALTMEALEDP SPELMEGPEE DIADKVVFLE RRVLELEKDT 
AATGEQHSRL RQENLQLVHR ANALEEQLKE QELRACEMVL EETRRQKELL CKMEREKSIE 
IENLQTRLQQ LDEENSELRS CTPCLKANIE RLEEEKQKLL DEIESLTLRL SEEQENKRRM 
GDRLSHERHQ FQRDKEATQE LIEDLRKQLE HLQLLKLEAE QRRGRSSSMG LQEYHSRARE 
SELEQEVRRL KQDNRNLKEQ NEELNGQIIT LSIQGAKSLF STAFSESLAA EISSVSRDEL 
MEAIQKQEEI NFRLQDYIDR IIVAIMETNP SILEVK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RAB11FIP3

Associated with

Other Information

Identification of a novel Rab11/25 binding domain present in eferin and rip proteins. PubMed ID: 11481332

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. PubMed ID: 9734811

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. PubMed ID: 11157797

The sequence and analysis of duplication-rich human chromosome 16. PubMed ID: 15616553

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries. PubMed ID: 12800201

Identification and characterization of a family of Rab11-interacting proteins. PubMed ID: 11495908

Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells. PubMed ID: 12470645

Rab11-FIP3 localises to a Rab11-positive pericentrosomal compartment during interphase and to the cleavage furrow during cytokinesis. PubMed ID: 15158446

Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis. PubMed ID: 16148947

The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. PubMed ID: 15601896

Molecular characterization of Rab11-FIP3 binding to ARF GTPases. PubMed ID: 17628206

Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene. PubMed ID: 17229837

Rab11-FIP3 is critical for the structural integrity of the endosomal recycling compartment. PubMed ID: 17394487

Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis. PubMed ID: 18511905

Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton. PubMed ID: 19327867

Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment. PubMed ID: 20026645

Rab11-FIP3 is a cell cycle-regulated phosphoprotein. PubMed ID: 22401586

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. PubMed ID: 25035494

The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting. PubMed ID: 25673879

Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis. PubMed ID: 31204173

Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes. PubMed ID: 17007872

Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1. PubMed ID: 17030804

Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11. PubMed ID: 26258637