Details for: KNTC1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: germ cell (CL0000586)
Fold Change: 2.04
Marker Score: 3,572 - Cell Name: mural cell (CL0008034)
Fold Change: 1.48
Marker Score: 169,222 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.32
Marker Score: 739 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.01
Marker Score: 15,772 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,792 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,017 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,406 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.96
Marker Score: 1,386 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.95
Marker Score: 492 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,409 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.94
Marker Score: 446 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,728 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5,096 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,296 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 313 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.87
Marker Score: 1,765 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.85
Marker Score: 513 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.8
Marker Score: 967 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,253 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.76
Marker Score: 515 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.74
Marker Score: 1,147 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.74
Marker Score: 563 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.74
Marker Score: 381 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.73
Marker Score: 237 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.71
Marker Score: 285 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.7
Marker Score: 4,229 - Cell Name: brush cell (CL0002204)
Fold Change: 0.69
Marker Score: 630 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.68
Marker Score: 6,995 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.67
Marker Score: 1,831 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 172 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.67
Marker Score: 192 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.67
Marker Score: 40,942 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.66
Marker Score: 822 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.65
Marker Score: 203 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.64
Marker Score: 1,510 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.64
Marker Score: 1,082 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.63
Marker Score: 2,659 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.63
Marker Score: 716 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.63
Marker Score: 5,959 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6
Marker Score: 1,792 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.58
Marker Score: 279 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.58
Marker Score: 2,245 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.56
Marker Score: 4,795 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.55
Marker Score: 555 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.55
Marker Score: 362 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.54
Marker Score: 718 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.54
Marker Score: 314 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.52
Marker Score: 451 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.52
Marker Score: 138 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.51
Marker Score: 383 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.49
Marker Score: 260 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.47
Marker Score: 210 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.47
Marker Score: 229 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.46
Marker Score: 376 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.45
Marker Score: 422 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.45
Marker Score: 4,199 - Cell Name: Unknown (CL0000548)
Fold Change: 0.45
Marker Score: 325 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.45
Marker Score: 1,722 - Cell Name: promyelocyte (CL0000836)
Fold Change: 0.44
Marker Score: 216 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.43
Marker Score: 578 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.42
Marker Score: 110 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.42
Marker Score: 6,310 - Cell Name: T-helper 17 cell (CL0000899)
Fold Change: 0.42
Marker Score: 277 - Cell Name: IgG plasmablast (CL0000982)
Fold Change: 0.42
Marker Score: 116 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.41
Marker Score: 456 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.41
Marker Score: 391 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.4
Marker Score: 372 - Cell Name: oocyte (CL0000023)
Fold Change: 0.4
Marker Score: 100 - Cell Name: IgA plasmablast (CL0000984)
Fold Change: 0.4
Marker Score: 104 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.38
Marker Score: 406 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.37
Marker Score: 157 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.37
Marker Score: 416 - Cell Name: neuron (CL0000540)
Fold Change: 0.37
Marker Score: 1,510 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.36
Marker Score: 2,791 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.36
Marker Score: 126 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.36
Marker Score: 1,481 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.36
Marker Score: 1,490 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.36
Marker Score: 208 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.35
Marker Score: 370 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.35
Marker Score: 1,446 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.34
Marker Score: 215 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.34
Marker Score: 12,561 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.34
Marker Score: 355 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.34
Marker Score: 169 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.34
Marker Score: 107 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.33
Marker Score: 138 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.33
Marker Score: 133 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.32
Marker Score: 391 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.32
Marker Score: 603 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.31
Marker Score: 84 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.31
Marker Score: 6,102 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.31
Marker Score: 209 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.3
Marker Score: 11,573 - Cell Name: interneuron (CL0000099)
Fold Change: 0.3
Marker Score: 139 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.3
Marker Score: 191 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.3
Marker Score: 482 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.29
Marker Score: 315 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.29
Marker Score: 182 - Cell Name: pre-conventional dendritic cell (CL0002010)
Fold Change: 0.28
Marker Score: 84
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4028545703
Symbol: KNTC1_HUMAN
Name: Kinetochore-associated protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8724849
Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 8724849
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11146660
Title: Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores.
PubMed ID: 11146660
DOI: 10.1038/35046598
PubMed ID: 11590237
Title: The ZW10 and Rough Deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore.
PubMed ID: 11590237
PubMed ID: 12686595
Title: Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.
PubMed ID: 12686595
PubMed ID: 15824131
Title: ZW10 links mitotic checkpoint signaling to the structural kinetochore.
PubMed ID: 15824131
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20462495
Title: Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.
PubMed ID: 20462495
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 2209
- Mass: 250749
- Checksum: 514C948733CBFDAC
- Sequence:
MWNDIELLTN DDTGSGYLSV GSRKEHGTAL YQVDLLVKIS SEKASLNPKI QACSLSDGFI IVADQSVILL DSICRSLQLH LVFDTEVDVV GLCQEGKFLL VGERSGNLHL IHVTSKQTLL TNAFVQKAND ENRRTYQNLV IEKDGSNEGT YYMLLLTYSG FFCITNLQLL KIQQAIENVD FSTAKKLQGQ IKSSFISTEN YHTLGCLSLV AGDLASEVPV IIGGTGNCAF SKWEPDSSKK GMTVKNLIDA EIIKGAKKFQ LIDNLLFVLD TDNVLSLWDI YTLTPVWNWP SLHVEEFLLT TEADSPSSVT WQGITNLKLI ALTASANKKM KNLMVYSLPT MEILYSLEVS SVSSLVQTGI STDTIYLLEG VCKNDPKLSE DSVSVLVLRC LTEALPENRL SRLLHKHRFA EAESFAIQFG LDVELVYKVK SNHILEKLAL SSVDASEQTE WQQLVDDAKE NLHKIQDDEF VVNYCLKAQW ITYETTQEML NYAKTRLLKK EDKTALIYSD GLKEVLRAHA KLTTFYGAFG PEKFSGSSWI EFLNNEDDLK DIFLQLKEGN LVCAQYLWLR HRANFESRFD VKMLESLLNS MSASVSLQKL CPWFKNDVIP FVRRTVPEGQ IILAKWLEQA ARNLELTDKA NWPENGLQLA EIFFTAEKTD ELGLASSWHW ISLKDYQNTE EVCQLRTLVN NLRELITLHR KYNCKLALSD FEKENTTTIV FRMFDKVLAP ELIPSILEKF IRVYMREHDL QEEELLLLYI EDLLNRCSSK STSLFETAWE AKAMAVIACL SDTDLIFDAV LKIMYAAVVP WSAAVEQLVK QHLEMDHPKV KLLQESYKLM EMKKLLRGYG IREVNLLNKE IMRVVRYILK QDVPSSLEDA LKVAQAFMLS DDEIYSLRII DLIDREQGED CLLLLKSLPP AEAEKTAERV IIWARLALQE EPDHSKEGKA WRMSVAKTSV DILKILCDIQ KDNLQKKDEC EEMLKLFKEV ASLQENFEVF LSFEDYSNSS LVADLREQHI KAHEVAQAKH KPGSTPEPIA AEVRSPSMES KLHRQALALQ MSKQELEAEL TLRALKDGNI KTALKKCSDL FKYHCNADTG KLLFLTCQKL CQMLADNVPV TVPVGLNLPS MIHDLASQAA TICSPDFLLD ALELCKHTLM AVELSRQCQM DDCGILMKAS FGTHKDPYEE WSYSDFFSED GIVLESQMVL PVIYELISSL VPLAESKRYP LESTSLPYCS LNEGDGLVLP VINSISALLQ NLQESSQWEL ALRFVVGSFG TCLQHSVSNF MNATLSEKLF GETTLVKSRH VVMELKEKAV IFIRENATTL LHKVFNCRLV DLDLALGYCT LLPQKDVFEN LWKLIDKAWQ NYDKILAISL VGSELASLYQ EIEMGLKFRE LSTDAQWGIR LGKLGISFQP VFRQHFLTKK DLIKALVENI DMDTSLILEY CSTFQLDCDA VLQLFIETLL HNTNAGQGQG DASMDSAKRR HPKLLAKALE MVPLLTSTKD LVISLSGILH KLDPYDYEMI EVVLKVIERA DEKITNININ QALSILKHLK SYRRISPPVD LEYQYMLEHV ITLPSAAQTR LPFHLIFFGT AQNFWKILST ELSEESFPTL LLISKLMKFS LDTLYVSTAK HVFEKKLKPK LLKLTQAKSS TLINKEITKI TQTIESCLLS IVNPEWAVAI AISLAQDIPE GSFKISALKF CLYLAERWLQ NIPSQDEKRE KAEALLKKLH IQYRRSGTEA VLIAHKLNTE EYLRVIGKPA HLIVSLYEHP SINQRIQNSS GTDYPDIHAA AKEIAEVNEI NLEKVWDMLL EKWLCPSTKP GEKPSELFEL QEDEALRRVQ YLLLSRPIDY SSRMLFVFAT STTTTLGMHQ LTFAHRTRAL QCLFYLADKE TIESLFKKPI EEVKSYLRCI TFLASFETLN IPITYELFCS SPKEGMIKGL WKNHSHESMA VRLVTELCLE YKIYDLQLWN GLLQKLLGFN MIPYLRKVLK AISSIHSLWQ VPYFSKAWQR VIQIPLLSAS CPLSPDQLSD CSESLIAVLE CPVSGDLDLI GVARQYIQLE LPAFALACLM LMPHSEKRHQ QIKNFLGSCD PQVILKQLEE HMNTGQLAGF SHQIRSLILN NIINKKEFGI LAKTKYFQML KMHAMNTNNI TELVNYLAND LSLDEASVLI TEYSKHCGKP VPPDTAPCEI LKMFLSGLS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.