Details for: ACAP1

Gene ID: 9744

Symbol: ACAP1

Ensembl ID: ENSG00000072818

Description: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

Associated with

Other Information

Genular Protein ID: 3522547253

Symbol: ACAP1_HUMAN

Name: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

UniProtKB Accession Codes:

Q15027 Q53XN9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 EMDB 2 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 5 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 7 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7584044

Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7584044

DOI: 10.1093/dnares/1.5.223

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11062263

Title: ACAPs are arf6 GTPase-activating proteins that function in the cell periphery.

PubMed ID: 11062263

DOI: 10.1083/jcb.151.3.627

PubMed ID: 16256741

Title: Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration.

PubMed ID: 16256741

DOI: 10.1016/j.devcel.2005.09.012

PubMed ID: 16777052

Title: Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry.

PubMed ID: 16777052

DOI: 10.1016/j.ab.2006.05.024

PubMed ID: 17010122

Title: Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation.

PubMed ID: 17010122

DOI: 10.1111/j.1600-0854.2006.00480.x

PubMed ID: 17398097

Title: Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP.

PubMed ID: 17398097

DOI: 10.1016/j.cub.2007.03.014

PubMed ID: 17664335

Title: An ACAP1-containing clathrin coat complex for endocytic recycling.

PubMed ID: 17664335

DOI: 10.1083/jcb.200608033

PubMed ID: 22645133

Title: Mechanistic insights into regulated cargo binding by ACAP1 protein.

PubMed ID: 22645133

DOI: 10.1074/jbc.m112.378810

PubMed ID: 25284369

Title: A PH domain in ACAP1 possesses key features of the BAR domain in promoting membrane curvature.

PubMed ID: 25284369

DOI: 10.1016/j.devcel.2014.08.020

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 740
  • Mass: 81536
  • Checksum: 64891DA3CE00189C
  • Sequence:
    • MTVKLDFEEC LKDSPRFRAS IELVEAEVSE LETRLEKLLK LGTGLLESGR HYLAASRAFV 
VGICDLARLG PPEPMMAECL EKFTVSLNHK LDSHAELLDA TQHTLQQQIQ TLVKEGLRGF 
REARRDFWRG AESLEAALTH NAEVPRRRAQ EAEEAGAALR TARAGYRGRA LDYALQINVI 
EDKRKFDIME FVLRLVEAQA THFQQGHEEL SRLSQYRKEL GAQLHQLVLN SAREKRDMEQ 
RHVLLKQKEL GGEEPEPSLR EGPGGLVMEG HLFKRASNAF KTWSRRWFTI QSNQLVYQKK 
YKDPVTVVVD DLRLCTVKLC PDSERRFCFE VVSTSKSCLL QADSERLLQL WVSAVQSSIA 
SAFSQARLDD SPRGPGQGSG HLAIGSAATL GSGGMARGRE PGGVGHVVAQ VQSVDGNAQC 
CDCREPAPEW ASINLGVTLC IQCSGIHRSL GVHFSKVRSL TLDSWEPELV KLMCELGNVI 
INQIYEARVE AMAVKKPGPS CSRQEKEAWI HAKYVEKKFL TKLPEIRGRR GGRGRPRGQP 
PVPPKPSIRP RPGSLRSKPE PPSEDLGSLH PGALLFRASG HPPSLPTMAD ALAHGADVNW 
VNGGQDNATP LIQATAANSL LACEFLLQNG ANVNQADSAG RGPLHHATIL GHTGLACLFL 
KRGADLGARD SEGRDPLTIA METANADIVT LLRLAKMREA EAAQGQAGDE TYLDIFRDFS 
LMASDDPEKL SRRSHDLHTL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.