Details for: HDAC4
Associated with
Other Information
Genular Protein ID: 2680446998
Symbol: HDAC4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10220385
Title: Three proteins define a class of human histone deacetylases related to yeast Hda1p.
PubMed ID: 10220385
PubMed ID: 9179496
Title: Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.
PubMed ID: 9179496
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10487761
Title: HDAC4 deacetylase associates with and represses the MEF2 transcription factor.
PubMed ID: 10487761
PubMed ID: 10523670
Title: HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.
PubMed ID: 10523670
PubMed ID: 10958686
Title: Regulation of histone deacetylase 4 by binding of 14-3-3 proteins.
PubMed ID: 10958686
PubMed ID: 11470791
Title: The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking.
PubMed ID: 11470791
PubMed ID: 11509672
Title: Identification of a signal-responsive nuclear export sequence in class II histone deacetylases.
PubMed ID: 11509672
PubMed ID: 11463856
Title: The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases.
PubMed ID: 11463856
PubMed ID: 12032081
Title: The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.
PubMed ID: 12032081
PubMed ID: 17373667
Title: Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases.
PubMed ID: 17373667
DOI: 10.1002/ijc.22673
PubMed ID: 17179159
Title: Nuclear calcium/calmodulin-dependent protein kinase IIdelta preferentially transmits signals to histone deacetylase 4 in cardiac cells.
PubMed ID: 17179159
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20691407
Title: Haploinsufficiency of HDAC4 causes brachydactyly mental retardation syndrome, with brachydactyly type E, developmental delays, and behavioral problems.
PubMed ID: 20691407
PubMed ID: 20110259
Title: Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX.
PubMed ID: 20110259
DOI: 10.1093/nar/gkq006
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23188045
Title: Phenotypic variant of Brachydactyly-mental retardation syndrome in a family with an inherited interstitial 2q37.3 microdeletion including HDAC4.
PubMed ID: 23188045
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24413532
Title: Differential regulation of estrogen receptor alpha expression in breast cancer cells by metastasis-associated protein 1.
PubMed ID: 24413532
PubMed ID: 24715439
Title: Haploinsufficiency of HDAC4 does not cause intellectual disability in all affected individuals.
PubMed ID: 24715439
DOI: 10.1002/ajmg.a.36542
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25752541
Title: Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.
PubMed ID: 25752541
PubMed ID: 27708256
Title: ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.
PubMed ID: 27708256
DOI: 10.1038/ncomms12882
PubMed ID: 30487602
Title: NP220 mediates silencing of unintegrated retroviral DNA.
PubMed ID: 30487602
PubMed ID: 22649097
Title: Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock.
PubMed ID: 22649097
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 24169519
Title: 20 ans apres: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.
PubMed ID: 24169519
PubMed ID: 33537682
Title: Missense substitutions at a conserved 14-3-3 binding site in HDAC4 cause a novel intellectual disability syndrome.
PubMed ID: 33537682
Sequence Information:
- Length: 1084
- Mass: 119040
- Checksum: BB7FD37652D12398
- Sequence:
MSSQSHPDGL SGRDQPVELL NPARVNHMPS TVDVATALPL QVAPSAVPMD LRLDHQFSLP VAEPALREQQ LQQELLALKQ KQQIQRQILI AEFQRQHEQL SRQHEAQLHE HIKQQQEMLA MKHQQELLEH QRKLERHRQE QELEKQHREQ KLQQLKNKEK GKESAVASTE VKMKLQEFVL NKKKALAHRN LNHCISSDPR YWYGKTQHSS LDQSSPPQSG VSTSYNHPVL GMYDAKDDFP LRKTASEPNL KLRSRLKQKV AERRSSPLLR RKDGPVVTAL KKRPLDVTDS ACSSAPGSGP SSPNNSSGSV SAENGIAPAV PSIPAETSLA HRLVAREGSA APLPLYTSPS LPNITLGLPA TGPSAGTAGQ QDAERLTLPA LQQRLSLFPG THLTPYLSTS PLERDGGAAH SPLLQHMVLL EQPPAQAPLV TGLGALPLHA QSLVGADRVS PSIHKLRQHR PLGRTQSAPL PQNAQALQHL VIQQQHQQFL EKHKQQFQQQ QLQMNKIIPK PSEPARQPES HPEETEEELR EHQALLDEPY LDRLPGQKEA HAQAGVQVKQ EPIESDEEEA EPPREVEPGQ RQPSEQELLF RQQALLLEQQ RIHQLRNYQA SMEAAGIPVS FGGHRPLSRA QSSPASATFP VSVQEPPTKP RFTTGLVYDT LMLKHQCTCG SSSSHPEHAG RIQSIWSRLQ ETGLRGKCEC IRGRKATLEE LQTVHSEAHT LLYGTNPLNR QKLDSKKLLG SLASVFVRLP CGGVGVDSDT IWNEVHSAGA ARLAVGCVVE LVFKVATGEL KNGFAVVRPP GHHAEESTPM GFCYFNSVAV AAKLLQQRLS VSKILIVDWD VHHGNGTQQA FYSDPSVLYM SLHRYDDGNF FPGSGAPDEV GTGPGVGFNV NMAFTGGLDP PMGDAEYLAA FRTVVMPIAS EFAPDVVLVS SGFDAVEGHP TPLGGYNLSA RCFGYLTKQL MGLAGGRIVL ALEGGHDLTA ICDASEACVS ALLGNELDPL PEKVLQQRPN ANAVRSMEKV MEIHSKYWRC LQRTTSTAGR SLIEAQTCEN EEAETVTAMA SLSVGVKPAE KRPDEEPMEE EPPL
Genular Protein ID: 3021194500
Symbol: A0A7I2SVS4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 1089
- Mass: 119704
- Checksum: 093216342C7D3B9C
- Sequence:
MSSQSHPDGL SGRDQPVELL NPARVNHMPS TVDVATALPL QVAPSAVPMD LRLDHQFSLP VAEPALREQQ LQQELLALKQ KQQIQRQILI AEFQRQHEQL SRQHEAQLHE HIKQQQEMLA MKHQQELLEH QRKLERHRQE QELEKQHREQ KLQQLKNKEK GKESAVASTE VKMKLQEFVL NKKKALAHRN LNHCISSDPR YWYGKTQHSS LDQSSPPQSG VSTSYNHPVL GMYDAKDDFP LRKTASEPNL KLRSRLKQKV AERRSSPLLR RKDGPVVTAL KKRPLDVTDS ACSSAPGSGP SSPNNSSGSV SAENGIAPAV PSIPAETSLA HRLVAREGSA APLPLYTSPS LPNITLGLPA TGPSAGTAGQ QDAERLTLPA LQQRLSLFPG THLTPYLSTS PLERDGGAAH SPLLQHMVLL EQPPAQAPLV TDWYLSGLGA LPLHAQSLVG ADRVSPSIHK LRQHRPLGRT QSAPLPQNAQ ALQHLVIQQQ HQQFLEKHKQ QFQQQQLQMN KIIPKPSEPA RQPESHPEET EEELREHQAL LDEPYLDRLP GQKEAHAQAG VQVKQEPIES DEEEAEPPRE VEPGQRQPSE QELLFRQQAL LLEQQRIHQL RNYQASMEAA GIPVSFGGHR PLSRAQSSPA SATFPVSVQE PPTKPRFTTG LVYDTLMLKH QCTCGSSSSH PEHAGRIQSI WSRLQETGLR GKCECIRGRK ATLEELQTVH SEAHTLLYGT NPLNRQKLDS KKLLGSLASV FVRLPCGGVG VDSDTIWNEV HSAGAARLAV GCVVELVFKV ATGELKNGFA VVRPPGHHAE ESTPMGFCYF NSVAVAAKLL QQRLSVSKIL IVDWDVHHGN GTQQAFYSDP SVLYMSLHRY DDGNFFPGSG APDEVGTGPG VGFNVNMAFT GGLDPPMGDA EYLAAFRTVV MPIASEFAPD VVLVSSGFDA VEGHPTPLGG YNLSARCFGY LTKQLMGLAG GRIVLALEGG HDLTAICDAS EACVSALLGN ELDPLPEKVL QQRPNANAVR SMEKVMEIHS KYWRCLQRTT STAGRSLIEA QTCENEEAET VTAMASLSVG VKPAEKRPDE EPMEEEPPL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.