Details for: ADGRE5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 68.7988
Cell Significance Index: -27.9500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 55.3962
Cell Significance Index: -28.5000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 52.3805
Cell Significance Index: -24.7300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 37.0182
Cell Significance Index: -24.8400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 29.4425
Cell Significance Index: -28.1100 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 15.1444
Cell Significance Index: 40.5700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.6413
Cell Significance Index: -23.4700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 6.5065
Cell Significance Index: -14.2400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.0283
Cell Significance Index: -13.4700 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.7033
Cell Significance Index: 86.9300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.9756
Cell Significance Index: 127.4600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.7894
Cell Significance Index: 291.0300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.2533
Cell Significance Index: 146.0600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1983
Cell Significance Index: 130.3400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.0352
Cell Significance Index: 62.1500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.8490
Cell Significance Index: 22.7100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6316
Cell Significance Index: 43.6800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.5628
Cell Significance Index: 16.5300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5440
Cell Significance Index: 15.6800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4508
Cell Significance Index: 246.1700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4229
Cell Significance Index: 41.8300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4016
Cell Significance Index: 8.7000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3855
Cell Significance Index: 348.1000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.3812
Cell Significance Index: 9.5300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.3177
Cell Significance Index: 4.7600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2384
Cell Significance Index: 47.3200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2366
Cell Significance Index: 10.7300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2237
Cell Significance Index: 17.1700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1934
Cell Significance Index: 36.8000 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.1626
Cell Significance Index: 1.0100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1153
Cell Significance Index: 20.7900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1050
Cell Significance Index: 3.6900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0967
Cell Significance Index: 11.9000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0824
Cell Significance Index: 11.3200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0712
Cell Significance Index: 2.0400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0322
Cell Significance Index: 1.6300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0291
Cell Significance Index: 3.7300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0151
Cell Significance Index: 11.4300 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.0046
Cell Significance Index: 0.0300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0023
Cell Significance Index: -0.3900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0042
Cell Significance Index: -6.4000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0063
Cell Significance Index: -11.8800 - Cell Name: mature T cell (CL0002419)
Fold Change: -0.0083
Cell Significance Index: -0.0600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0127
Cell Significance Index: -23.3800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0168
Cell Significance Index: -22.8000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0170
Cell Significance Index: -2.1900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0184
Cell Significance Index: -0.3600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0257
Cell Significance Index: -11.6800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0283
Cell Significance Index: -0.9100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0315
Cell Significance Index: -6.3200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0327
Cell Significance Index: -1.7000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0343
Cell Significance Index: -0.7300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0376
Cell Significance Index: -27.8600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0388
Cell Significance Index: -28.4800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0405
Cell Significance Index: -25.7400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0428
Cell Significance Index: -18.9200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0429
Cell Significance Index: -15.3900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0474
Cell Significance Index: -2.2300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0480
Cell Significance Index: -29.9600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0492
Cell Significance Index: -27.7400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0561
Cell Significance Index: -6.6200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0741
Cell Significance Index: -21.3100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0854
Cell Significance Index: -8.7300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1049
Cell Significance Index: -12.0200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1308
Cell Significance Index: -27.5600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1596
Cell Significance Index: -23.2000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1651
Cell Significance Index: -8.6000 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1768
Cell Significance Index: -1.8300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2057
Cell Significance Index: -21.4200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2153
Cell Significance Index: -5.5000 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.2256
Cell Significance Index: -1.2300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2306
Cell Significance Index: -10.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2745
Cell Significance Index: -20.4600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2884
Cell Significance Index: -7.7000 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.2947
Cell Significance Index: -5.0800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3174
Cell Significance Index: -19.4600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3334
Cell Significance Index: -23.5800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3531
Cell Significance Index: -23.7400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3970
Cell Significance Index: -25.0200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3997
Cell Significance Index: -11.1700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4116
Cell Significance Index: -25.3000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4158
Cell Significance Index: -21.8300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.4195
Cell Significance Index: -23.5400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4431
Cell Significance Index: -11.3900 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.4595
Cell Significance Index: -3.8600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.4673
Cell Significance Index: -19.1500 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: -0.4750
Cell Significance Index: -4.9300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5337
Cell Significance Index: -23.6100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.5694
Cell Significance Index: -9.5300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5785
Cell Significance Index: -20.2700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.5971
Cell Significance Index: -14.5700 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.6267
Cell Significance Index: -13.0000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6338
Cell Significance Index: -24.0000 - Cell Name: peg cell (CL4033014)
Fold Change: -0.6341
Cell Significance Index: -14.6500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.6415
Cell Significance Index: -23.5500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6491
Cell Significance Index: -21.2500 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.6511
Cell Significance Index: -12.7300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6615
Cell Significance Index: -17.4000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.6617
Cell Significance Index: -18.0100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6735
Cell Significance Index: -21.4500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1276686024
Symbol: AGRE5_HUMAN
Name: Adhesion G protein-coupled receptor E5 subunit alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7636245
Title: Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain.
PubMed ID: 7636245
PubMed ID: 8786105
Title: Structure of the human CD97 gene: exon shuffling has generated a new type of seven-span transmembrane molecule related to the secretin receptor superfamily.
PubMed ID: 8786105
PubMed ID: 8955192
Title: CD97 is a processed, seven-transmembrane, heterodimeric receptor associated with inflammation.
PubMed ID: 8955192
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11297558
Title: Molecular analysis of the epidermal growth factor-like short consensus repeat domain-mediated protein-protein interactions: dissection of the CD97-CD55 complex.
PubMed ID: 11297558
PubMed ID: 12829604
Title: The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans.
PubMed ID: 12829604
PubMed ID: 14647991
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 835
- Mass: 91869
- Checksum: 06DDDE9178BC494B
- Sequence:
MGGRVFLAFC VWLTLPGAET QDSRGCARWC PQNSSCVNAT ACRCNPGFSS FSEIITTPTE TCDDINECAT PSKVSCGKFS DCWNTEGSYD CVCSPGYEPV SGAKTFKNES ENTCQDVDEC QQNPRLCKSY GTCVNTLGSY TCQCLPGFKF IPEDPKVCTD VNECTSGQNP CHSSTHCLNN VGSYQCRCRP GWQPIPGSPN GPNNTVCEDV DECSSGQHQC DSSTVCFNTV GSYSCRCRPG WKPRHGIPNN QKDTVCEDMT FSTWTPPPGV HSQTLSRFFD KVQDLGRDSK TSSAEVTIQN VIKLVDELME APGDVEALAP PVRHLIATQL LSNLEDIMRI LAKSLPKGPF TYISPSNTEL TLMIQERGDK NVTMGQSSAR MKLNWAVAAG AEDPGPAVAG ILSIQNMTTL LANASLNLHS KKQAELEEIY ESSIRGVQLR RLSAVNSIFL SHNNTKELNS PILFAFSHLE SSDGEAGRDP PAKDVMPGPR QELLCAFWKS DSDRGGHWAT EGCQVLGSKN GSTTCQCSHL SSFAILMAHY DVEDWKLTLI TRVGLALSLF CLLLCILTFL LVRPIQGSRT TIHLHLCICL FVGSTIFLAG IENEGGQVGL RCRLVAGLLH YCFLAAFCWM SLEGLELYFL VVRVFQGQGL STRWLCLIGY GVPLLIVGVS AAIYSKGYGR PRYCWLDFEQ GFLWSFLGPV TFIILCNAVI FVTTVWKLTQ KFSEINPDMK KLKKARALTI TAIAQLFLLG CTWVFGLFIF DDRSLVLTYV FTILNCLQGA FLYLLHCLLN KKVREEYRKW ACLVAGGSKY SEFTSTTSGT GHNQTRALRA SESGI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.