Details for: CD151
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 337.8439
Cell Significance Index: -52.5500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 211.3992
Cell Significance Index: -53.6200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 122.9447
Cell Significance Index: -58.0500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 109.8593
Cell Significance Index: -56.5100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 87.7020
Cell Significance Index: -58.8500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 45.2977
Cell Significance Index: -55.8500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 17.9778
Cell Significance Index: -48.1600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.2244
Cell Significance Index: -56.1300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.4566
Cell Significance Index: -38.2600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 10.3922
Cell Significance Index: 1211.1000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 5.1059
Cell Significance Index: 238.0600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 4.6007
Cell Significance Index: 81.3000 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 4.5554
Cell Significance Index: 28.0400 - Cell Name: kidney cell (CL1000497)
Fold Change: 3.9240
Cell Significance Index: 31.3300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.7127
Cell Significance Index: 24.9800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.4911
Cell Significance Index: 28.3000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 2.2330
Cell Significance Index: 33.4600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.1469
Cell Significance Index: 1172.4500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.0467
Cell Significance Index: 96.2000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.0188
Cell Significance Index: 277.2400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.0064
Cell Significance Index: 149.5400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.7102
Cell Significance Index: 37.0500 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.6319
Cell Significance Index: 210.8300 - Cell Name: peg cell (CL4033014)
Fold Change: 1.5149
Cell Significance Index: 35.0000 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.4404
Cell Significance Index: 8.9500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.3866
Cell Significance Index: 137.1700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.2641
Cell Significance Index: 558.8800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.2337
Cell Significance Index: 222.3900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.1678
Cell Significance Index: 40.5800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.1314
Cell Significance Index: 139.1200 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.1139
Cell Significance Index: 142.7900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.0490
Cell Significance Index: 179.1200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.0076
Cell Significance Index: 52.3400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.0040
Cell Significance Index: 71.0100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9429
Cell Significance Index: 851.3500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.9220
Cell Significance Index: 26.5700 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.8699
Cell Significance Index: 11.1400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.8276
Cell Significance Index: 22.1800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.7561
Cell Significance Index: 20.1900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.6245
Cell Significance Index: 16.4200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5897
Cell Significance Index: 16.0500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4509
Cell Significance Index: 85.8000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.2027
Cell Significance Index: 23.1400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.1905
Cell Significance Index: 144.2000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1539
Cell Significance Index: 0.9300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1320
Cell Significance Index: 26.1900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1074
Cell Significance Index: 17.4600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0789
Cell Significance Index: 2.7700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0728
Cell Significance Index: 1.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0676
Cell Significance Index: 13.5700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0673
Cell Significance Index: 46.5300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0583
Cell Significance Index: 1.6700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0535
Cell Significance Index: 0.9000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0186
Cell Significance Index: 35.0900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0035
Cell Significance Index: -4.7300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0088
Cell Significance Index: -6.4600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0124
Cell Significance Index: -1.2700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0179
Cell Significance Index: -27.5400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0188
Cell Significance Index: -34.5900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0201
Cell Significance Index: -14.9200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0326
Cell Significance Index: -20.3500 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.0384
Cell Significance Index: -0.8000 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.0476
Cell Significance Index: -0.4000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0500
Cell Significance Index: -31.7700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0508
Cell Significance Index: -3.9000 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: -0.0658
Cell Significance Index: -0.3200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0691
Cell Significance Index: -24.8000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0758
Cell Significance Index: -42.7700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0868
Cell Significance Index: -39.3900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1013
Cell Significance Index: -11.6100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1255
Cell Significance Index: -26.4400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1537
Cell Significance Index: -44.2100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1544
Cell Significance Index: -10.6800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2398
Cell Significance Index: -7.6800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2490
Cell Significance Index: -6.9600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2912
Cell Significance Index: -42.3300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3190
Cell Significance Index: -16.7500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.3716
Cell Significance Index: -4.0400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4197
Cell Significance Index: -49.5000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.4556
Cell Significance Index: -29.3900 - Cell Name: supporting cell (CL0000630)
Fold Change: -0.4590
Cell Significance Index: -2.1200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.4904
Cell Significance Index: -22.2300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5165
Cell Significance Index: -53.7800 - Cell Name: perivascular cell (CL4033054)
Fold Change: -0.5599
Cell Significance Index: -2.5900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.6296
Cell Significance Index: -35.3300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.6607
Cell Significance Index: -40.6100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6721
Cell Significance Index: -53.2300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.6750
Cell Significance Index: -9.2100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7440
Cell Significance Index: -45.6200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.7809
Cell Significance Index: -15.2400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.8037
Cell Significance Index: -20.0900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.8129
Cell Significance Index: -23.8700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.8324
Cell Significance Index: -55.9700 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.8605
Cell Significance Index: -15.9100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8680
Cell Significance Index: -54.7100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.9125
Cell Significance Index: -19.1000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.9220
Cell Significance Index: -15.8000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.9591
Cell Significance Index: -28.2500 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -1.0301
Cell Significance Index: -10.6600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.0905
Cell Significance Index: -28.0300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4057369447
Symbol: CD151_HUMAN
Name: CD151 antigen
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7632941
Title: Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3.
PubMed ID: 7632941
PubMed ID: 8627808
Title: SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily.
PubMed ID: 8627808
PubMed ID: 11181065
Title: Genomic organization, amplification, fine mapping, and intragenic polymorphisms of the human hemidesmosomal tetraspanin CD151 gene.
PubMed ID: 11181065
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11907260
Title: Palmitoylation of tetraspanin proteins: modulation of CD151 lateral interactions, subcellular distribution, and integrin-dependent cell morphology.
PubMed ID: 11907260
PubMed ID: 15265795
Title: CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.
PubMed ID: 15265795
PubMed ID: 17045834
Title: Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates CD151-induced endothelial cell proliferation and cell migration.
PubMed ID: 17045834
PubMed ID: 18713730
Title: The single subunit transmembrane E3 ligase gene related to anergy in lymphocytes (GRAIL) captures and then ubiquitinates transmembrane proteins across the cell membrane.
PubMed ID: 18713730
PubMed ID: 18852263
Title: Tetraspanin CD151 regulates glycosylation of (alpha)3(beta)1 integrin.
PubMed ID: 18852263
PubMed ID: 18508921
Title: DHHC2 affects palmitoylation, stability, and functions of tetraspanins CD9 and CD151.
PubMed ID: 18508921
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22843693
Title: Tetraspanin CD151 stimulates adhesion-dependent activation of Ras, Rac, and Cdc42 by facilitating molecular association between beta1 integrins and small GTPases.
PubMed ID: 22843693
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24723389
Title: Tetraspanins CD9 and CD151 at the immune synapse support T-cell integrin signaling.
PubMed ID: 24723389
PubMed ID: 24553111
PubMed ID: 27147745
Title: Tetraspanin CD151 Promotes Initial Events in Human Cytomegalovirus Infection.
PubMed ID: 27147745
DOI: 10.1128/jvi.00145-16
PubMed ID: 27993971
Title: The CD9, CD81, and CD151 EC2 domains bind to the classical RGD-binding site of integrin alphavbeta3.
PubMed ID: 27993971
DOI: 10.1042/bcj20160998
PubMed ID: 31488507
Title: Tetraspanin CD151 and integrin alpha3beta1 contribute to the stabilization of integrin alpha6beta4-containing cell-matrix adhesions.
PubMed ID: 31488507
DOI: 10.1242/jcs.235366
PubMed ID: 32978478
Title: The tetraspanin CD151 marks a unique population of activated human T cells.
PubMed ID: 32978478
PubMed ID: 35067832
Title: JAM-A interacts with alpha3beta1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells.
PubMed ID: 35067832
Sequence Information:
- Length: 253
- Mass: 28295
- Checksum: 0C8FE4CF2C3C286D
- Sequence:
MGEFNEKKTT CGTVCLKYLL FTYNCCFWLA GLAVMAVGIW TLALKSDYIS LLASGTYLAT AYILVVAGTV VMVTGVLGCC ATFKERRNLL RLYFILLLII FLLEIIAGIL AYAYYQQLNT ELKENLKDTM TKRYHQPGHE AVTSAVDQLQ QEFHCCGSNN SQDWRDSEWI RSQEAGGRVV PDSCCKTVVA LCGQRDHASN IYKVEGGCIT KLETFIQEHL RVIGAVGIGI ACVQVFGMIF TCCLYRSLKL EHY
Genular Protein ID: 1807719036
Symbol: Q6ZNZ0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 179
- Mass: 18926
- Checksum: 6A18B6EC57335AC1
- Sequence:
MGEFNEKKTT CGTVCLKYLL FTYNCCFWLA GLAVMAVGIW TLALKSDYIS LLASGTYLAT AYILVVAGTV VMVTGVLGCC ATFKERRNLL RLVRRAQGHG VGVVQMGPRR LSLQALNLCL AVLTWGGVTV LPHLPSPVGP HVPAGPAEGR HQLRKKASGR VAAPQPPPGA WGAGVGTLL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.