RASSF2 | ENSG00000101265 | NCBI 9770

Details for: RASSF2

Gene ID: 9770

Symbol: RASSF2

Ensembl ID: ENSG00000101265

Description: Ras association domain family member 2

Associated with

Bone remodeling
(GO:0046849)
Canonical nf-kappab signal transduction
(GO:0007249)
Cell cycle
(GO:0007049)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Golgi apparatus
(GO:0005794)
Homeostasis of number of cells
(GO:0048872)
Kinetochore
(GO:0000776)
Negative regulation of non-canonical nf-kappab signal transduction
(GO:1901223)
Negative regulation of peptidyl-serine phosphorylation
(GO:0033137)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Ossification
(GO:0001503)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of jnk cascade
(GO:0046330)
Positive regulation of protein autophosphorylation
(GO:0031954)
Positive regulation of protein kinase activity
(GO:0045860)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein stabilization
(GO:0050821)
Regulation of non-canonical nf-kappab signal transduction
(GO:1901222)
Regulation of osteoblast differentiation
(GO:0045667)
Regulation of osteoclast differentiation
(GO:0045670)
Signal transduction
(GO:0007165)
Skeletal system development
(GO:0001501)

Other Information

Proteins

Ras association domain-containing protein 2

Genular Protein ID: 438194915

Symbol: RASF2_HUMAN

Name: Ras association domain-containing protein 2

UniProtKB Accession Codes:

P50749 A6NIX9 A8K5Z3 Q17S06 Q53HD0 Q6AHZ2 Q8IZA5

Database IDs:

Citations:

PubMed ID: 8724849

Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8724849

DOI: 10.1093/dnares/3.1.17

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12732644

Title: RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor.

PubMed ID: 12732644

DOI: 10.1074/jbc.m300554200

PubMed ID: 16012945

Title: The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.

PubMed ID: 16012945

DOI: 10.1053/j.gastro.2005.03.051

PubMed ID: 15569673

Title: Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes.

PubMed ID: 15569673

DOI: 10.1074/jbc.m409701200

PubMed ID: 19525978

Title: RASSF2 associates with and stabilizes the proapoptotic kinase MST2.

PubMed ID: 19525978

DOI: 10.1038/onc.2009.152

PubMed ID: 20813266

Title: The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics.

PubMed ID: 20813266

DOI: 10.1016/j.cell.2010.07.047

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 326
Mass: 37790
Checksum: C29D16376904249E
Sequence:

MDYSHQTSLV PCGQDKYISK NELLLHLKTY NLYYEGQNLQ LRHREEEDEF IVEGLLNISW 
GLRRPIRLQM QDDNERIRPP PSSSSWHSGC NLGAQGTTLK PLTVPKVQIS EVDAPPEGDQ 
MPSSTDSRGL KPLQEDTPQL MRTRSDVGVR RRGNVRTPSD QRRIRRHRFS INGHFYNHKT 
SVFTPAYGSV TNVRINSTMT TPQVLKLLLN KFKIENSAEE FALYVVHTSG EKQKLKATDY 
PLIARILQGP CEQISKVFLM EKDQVEEVTY DVAQYIKFEM PVLKSFIQKL QEEEDREVKK 
LMRKYTVLRL MIRQRLEEIA ETPATI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RASSF2

Associated with

Other Information

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. PubMed ID: 8724849

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. PubMed ID: 12732644

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. PubMed ID: 16012945

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes. PubMed ID: 15569673

RASSF2 associates with and stabilizes the proapoptotic kinase MST2. PubMed ID: 19525978

The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. PubMed ID: 20813266

Initial characterization of the human central proteome. PubMed ID: 21269460

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974