Details for: ATG13

Gene ID: 9776

Symbol: ATG13

Ensembl ID: ENSG00000175224

Description: autophagy related 13

Associated with

Other Information

Genular Protein ID: 1018795395

Symbol: ATG13_HUMAN

Name: Autophagy-related protein 13

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19597335

Title: Atg101, a novel mammalian autophagy protein interacting with Atg13.

PubMed ID: 19597335

DOI: 10.4161/auto.5.7.9296

PubMed ID: 19287211

Title: A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

PubMed ID: 19287211

DOI: 10.4161/auto.5.5.8249

PubMed ID: 19211835

Title: Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

PubMed ID: 19211835

DOI: 10.1091/mbc.e08-12-1248

PubMed ID: 19225151

Title: ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

PubMed ID: 19225151

DOI: 10.1091/mbc.e08-12-1249

PubMed ID: 21855797

Title: Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.

PubMed ID: 21855797

DOI: 10.1016/j.molcel.2011.06.018

PubMed ID: 18936157

Title: Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

PubMed ID: 18936157

DOI: 10.1128/mcb.01082-08

PubMed ID: 21795849

Title: ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.

PubMed ID: 21795849

DOI: 10.4161/auto.7.10.16660

PubMed ID: 21258367

Title: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

PubMed ID: 21258367

DOI: 10.1038/ncb2152

PubMed ID: 21976705

Title: TGFbeta-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy.

PubMed ID: 21976705

DOI: 10.1093/jb/mvr123

PubMed ID: 23043107

Title: ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

PubMed ID: 23043107

DOI: 10.1074/jbc.m112.378109

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27334615

Title: The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.

PubMed ID: 27334615

DOI: 10.15252/embj.201694401

PubMed ID: 31806350

Title: The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1.

PubMed ID: 31806350

DOI: 10.1016/j.molcel.2019.10.035

PubMed ID: 24290141

Title: Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.

PubMed ID: 24290141

DOI: 10.1016/j.str.2013.09.023

PubMed ID: 26236954

Title: The mammalian autophagy initiator complex contains 2 HORMA domain proteins.

PubMed ID: 26236954

DOI: 10.1080/15548627.2015.1076605

PubMed ID: 26299944

Title: Structure of the human Atg13-Atg101 HORMA heterodimer: an interaction hub within the ULK1 complex.

PubMed ID: 26299944

DOI: 10.1016/j.str.2015.07.011

Sequence Information:

  • Length: 517
  • Mass: 56572
  • Checksum: 4D6905985EAB78A7
  • Sequence:
  • METDLNSQDR KDLDKFIKFF ALKTVQVIVQ ARLGEKICTR SSSSPTGSDW FNLAIKDIPE 
    VTHEAKKALA GQLPAVGRSM CVEISLKTSE GDSMELEIWC LEMNEKCDKE IKVSYTVYNR 
    LSLLLKSLLA ITRVTPAYRL SRKQGHEYVI LYRIYFGEVQ LSGLGEGFQT VRVGTVGTPV 
    GTITLSCAYR INLAFMSTRQ FERTPPIMGI IIDHFVDRPY PSSSPMHPCN YRTAGEDTGV 
    IYPSVEDSQE VCTTSFSTSP PSQLSSSRLS YQPAALGVGS ADLAYPVVFA AGLNATHPHQ 
    LMVPGKEGGV PLAPNQPVHG TQADQERLAT CTPSDRTHCA ATPSSSEDTE TVSNSSEGRA 
    SPHDVLETIF VRKVGAFVNK PINQVTLTSL DIPFAMFAPK NLELEDTDPM VNPPDSPETE 
    SPLQGSLHSD GSSGGSSGNT HDDFVMIDFK PAFSKDDILP MDLGTFYREF QNPPQLSSLS 
    IDIGAQSMAE DLDSLPEKLA VHEKNVREFD AFVETLQ

Genular Protein ID: 4239244664

Symbol: A8K0S6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 517
  • Mass: 56582
  • Checksum: 4D1B94485E6479B8
  • Sequence:
  • METDLNSQDR KDLDKFIKFF ALKTVQVIVQ ARLGEKICTR SSSSPTGSDW FNLAIKDIPE 
    VTHEAKKALA GQLPAVGRSM CVEISLKTSE GDSMELEIWC LEMNEKCDKE IKVSYTVYNR 
    LSLLLKSLLA ITRVTPAYRL PRKQGHEYVI LYRIYFGEVQ LSGLGEGFQT VRVGTVGTPV 
    GTITLSCAYR INLAFMSTRQ FERTPPIMGI IIDHFVDRPY PSSSPMHPCN YRTAGEDTGV 
    IYPSVEDSQE VCTTSFSTSP PSQLSSSRLS YQPAALGVGS ADLAYPVVFA AGLNATHPHQ 
    LMVPGKEGGV PLAPNQPVHG TQADQERLAT CTPSDRTHCA ATPSSSEDTE TVSNSSEGRA 
    SPHDVLETIF VRKVGAFVNK PINQVTLTSL DIPFAMFAPK NLELEDTDPM VNPPDSPETE 
    SPLQGSLHSD GSSGGSSGNT HDDFVMIDFK PAFSKDDILP MDLGTFYREF QNPPQLSSLS 
    IDIGAQSMAE DLDSLPEKLA VHEKNVREFD AFVETLQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.