Details for: KIAA0586
Associated with
Other Information
Genular Protein ID: 1385581878
Symbol: TALD3_HUMAN
Name: Protein TALPID3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9628581
Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9628581
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19144723
Title: The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation.
PubMed ID: 19144723
DOI: 10.1242/dev.028464
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24421332
Title: The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.
PubMed ID: 24421332
PubMed ID: 26166481
Title: Mutations in KIAA0586 cause lethal ciliopathies ranging from a hydrolethalus phenotype to short-rib polydactyly syndrome.
PubMed ID: 26166481
PubMed ID: 26026149
Title: Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome.
PubMed ID: 26026149
DOI: 10.7554/elife.06602
PubMed ID: 26386247
Title: TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23).
PubMed ID: 26386247
DOI: 10.7554/elife.08077
PubMed ID: 26096313
PubMed ID: 26386044
Title: Mutations in human homologue of chicken talpid3 gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromes.
PubMed ID: 26386044
PubMed ID: 26429889
Title: A human laterality disorder caused by a homozygous deleterious mutation in MMP21.
PubMed ID: 26429889
Sequence Information:
- Length: 1533
- Mass: 169307
- Checksum: 031F5F28D63FD612
- Sequence:
MPVKRLREVV SQNHGDHLVL LKDELPCVPP ALSANKRLPV GTGTSLNGTS RGSSDLTSAR NCYQPLLENP MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG VSGDASTNET YLPARVCTPL PTPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
Genular Protein ID: 1364111644
Symbol: B4DYW5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1463
- Mass: 161733
- Checksum: 6C0A522F5BD9982A
- Sequence:
MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASPPP VQTWIKTPEI MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG VSGDASTNET YLPARVCTPL ATPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
Genular Protein ID: 766309404
Symbol: A0A494C171_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
Sequence Information:
- Length: 1548
- Mass: 171022
- Checksum: CB8F7DBADCFCEC98
- Sequence:
MKGSEVSLEK KKKIKMPVKR LREVVSQNHG DHLVLLKDEL PCVPPALSAN KRLPVGTGTS LNGTSRGSSD LTSARNCYQP LLENPMVSES DFSKDVAVQV LPLDKIEENN KQKANDIFIS QYTMGQKDAL RTVLKQKAQS MPVFKEVKVH LLEDAGIEKD AVTQETRISP SGIDSATTVA AATAAAIATA APLIKVQSDL EAKVNSVTEL LSKLQETDKH LQRVTEQQTS IQRKQEKLHC HDHEKQMNVF MEQHIRHLEK LQQQQIDIQT HFISAALKTS SFQPVSMPSS RAVEKYSVKP EHPNLGSCNP SLYNTFASKQ APLKEVEDTS FDKQKSPLET PAPRRFAPVP VSRDDELSKR ENLLEEKENM EVSCHRGNVR LLEQILNNND SLTRKSESSN TTSLTRSKIG WTPEKTNRFP SCEELETTKV TMQKSDDVLH DLGQKEKETN SMVQPKESLS MLKLPDLPQN SVKLQTTNTT RSVLKDAEKI LRGVQNNKKV LEENLEAIIR AKDGAAMYSL INALSTNREM SEKIRIRKTV DEWIKTISAE IQDELSRTDY EQKRFDQKNQ RTKKGQNMTK DIRTNTQDKT VNKSVIPRKH SQKQIEEHFR NLPMRGMPAS SLQKERKEGL LKATTVIQDE DYMLQVYGKP VYQGHRSTLK KGPYLRFNSP SPKSRPQRPK VIERVKGTKV KSIRTQTDFY ATKPKKMDSK MKHSVPVLPH GDQQYLFSPS REMPTFSGTL EGHLIPMAIL LGQTQSNSDT MPPAGVIVSK PHPVTVTTSI PPSSRKVETG VKKPNIAIVE MKSEKKDPPQ LTVQVLPSVD IDSISNSSAD VLSPLSSPKE ASLPPVQTWI KTPEIMKVDE EEVKFPGTNF DEIIDVIQEE EKCDEIPDSE PILEFNRSVK ADSTKYNGPP FPPVASTFQP TADILDKVIE RKETLENSLI QWVEQEIMSR IISGLFPVQQ QIAPSISVSV SETSEPLTSD IVEGTSSGAL QLFVDAGVPV NSNVIKHFVN EALAETIAVM LGDREAKKQG PVATGVSGDA STNETYLPAR VCTPLPTPQP TPPCSPSSPA KECVLVKTPD SSPCDSDHDM AFPVKEICAE KGDDMPAIML VNTPTVTPTT TPPPAAAVFT PTLSDISIDK LKVSSPELPK PWGDGDLPLE EENPNSPQEE LHPRAIVMSV AKDEEPESMD FPAQPPPPEP VPFMPFPAGT KAPSPSQMPG SDSSTLESTL SVTVTETETL DKPISEGEIL FSCGQKLAPK ILEDIGLYLT NLNDSLSSTL HDAVEMEDDP PSEGQVIRMS HKKFHADAIL SFAKQNQESA VSQQAVYHSE DLENSVGELS EGQRPQLTAA AENILMGHSL YMQPPVTNTQ SLDQQCDPKP LSRQFDTVSG SIYEDSCASH GPMSLGELEL EPNSKLVLPT TLLTAQENDV NLPVAAEDFS QYQLKQNQDV KQVEHKPSQS YLRVRNKSDI APSQQQVSPG DMDRTQIELN PYLTCVFSGG KAVPLSASQM PPAKMSVMLP SVNLEDCSQS LSLSTMQEDM ESSGADTF
Genular Protein ID: 3346723906
Symbol: A0A087WYM5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 1463
- Mass: 161775
- Checksum: E28D5A2FBDB7793D
- Sequence:
MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG VSGDASTNET YLPARVCTPL PTPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
Genular Protein ID: 1153064206
Symbol: B7Z7W7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1347
- Mass: 149150
- Checksum: EBE979E24BF57FD1
- Sequence:
MPVFKEVKVH LLEDAGIEKD AVTQETRISP SGIDSATTVA AATAAAIATA APLIKVQSDL EAKVNSVTEL LSKLQETDKH LQRVTEQQTS IQRKQEKLHC HDHEKQMNVF MEQHIRHLEK LQQQQIDIQT HFISAALKTS SFQPVSMPSS RAVEKYSVKP EHPNLGSCNP SLYNTFASKQ APLKEVEDTS FDKQKSPLET PAPRRFAPVP VSRDDELSKR ENLLEEKENM EVSCHRGNVR LLEQILNNND SLTRKSESSN TTSLTRSKIG WTPEKTNRFP SCEELETTKV TMQKSDDVLH DLGQKEKETN SMVQPKESLS MLKLPDLPQN SVKLQTTNTT RSVLKDAEKI LRGVQNNKKV LEENLEAIIR AKDGAAMYSL INALSTNREM SEKIRIRKTV DEWIKTISAE IQDELSRTDY EQKRFDQKNQ RTKKGQNMTK DIRTNTQDKT VNKSVIPRKH SQKQIEEHFR NLPMRGMPAS SLQKERKEGL LKATTVIQDE DYMLQVYGKP VYQGHRSTLK KGPYLRFNSP SPKSRPQRPK VIERVKGTKV KSIRTQTDFY ATKPKKMDSK MKHSVPVLPH GDQQYLFSPS REMPTFSGTL EGHLIPMAIL LGQTQSNSDT MPPAGVIVSK PHPVTVTTSI PPSSRKVETG VKKPNIAIVE MKSEKKDPPQ LTVQVLPSVD IDSISNSSAD VLSPLSSPKE ASPPPVQTWI KTPEIMKVDE EEVKFPGTNF DEIIDVIQEE EKCDEIPDSE PILEFNRSVK ADSTKYNGPP FPPVASTFQP TADILDKVIE RKETLENSLI QWVEQEIMSR IISGLFPVQQ QIAPSISVSV SETSEPLTSD IVEGTSSGAL QLFVDAGVPV NSNVIKHFVN EALAETIAVM LGDREAKKQG PVATGVSGDA STNETYLPAR VCTPLATPQP TPPCSPSSPA KECVLVKTPD SSPCDSDHDM AFPVKEICAE KGDDMPAIML VNTPTVTPTT TPPPAAAVFT PTLSDISIDK LKVSSPELPK PWGDGDLPLE EENPNSPQEE LHPRAIVMSV AKDEEPESMD FPAQPPPPEP VPFMPFPAGT KAPSPSQMPG SDSSTLESTL SVTVTETETL DKPISEGEIL FSCGQKLAPK ILEDIGLYLT NLNDSLSSTL HDAVEMEDDP PSEGQVIRMS HKKFHADAIL SFAKQNQESA VSQQAVYHSE DLENSVGELS EGQRPQLTAA AENILMGHSL YMQPPVTNTQ SLDQQCDPKP LSRQFDTVSG SIYEDSCASH GPMSLGELEL EPNSKLVLPT TLLTAQENDV NLPVAAEDFS QYQLKQNQDV KQVEHKPSQS YLRVRNKSDI APSQQQVLIS RIKNCKN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.