SPCS2 | ENSG00000118363 | NCBI 9789

Details for: SPCS2

Gene ID: 9789

Symbol: SPCS2

Ensembl ID: ENSG00000118363

Description: signal peptidase complex subunit 2

Associated with

Disease
(R-HSA-1643685)
Incretin synthesis, secretion, and inactivation
(R-HSA-400508)
Infectious disease
(R-HSA-5663205)
Maturation of hrsv a proteins
(R-HSA-9828806)
Metabolism of proteins
(R-HSA-392499)
Peptide hormone metabolism
(R-HSA-2980736)
Respiratory syncytial virus (rsv) genome replication, transcription and translation
(R-HSA-9820965)
Respiratory syncytial virus infection pathway
(R-HSA-9820952)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Synthesis, secretion, and deacylation of ghrelin
(R-HSA-422085)
Synthesis, secretion, and inactivation of glucagon-like peptide-1 (glp-1)
(R-HSA-381771)
Synthesis, secretion, and inactivation of glucose-dependent insulinotropic polypeptide (gip)
(R-HSA-400511)
Translation
(R-HSA-72766)
Viral infection pathways
(R-HSA-9824446)
Endoplasmic reticulum membrane
(GO:0005789)
Protein binding
(GO:0005515)
Protein targeting to er
(GO:0045047)
Signal peptidase complex
(GO:0005787)
Signal peptide processing
(GO:0006465)

Other Information

Proteins

Signal peptidase complex subunit 2

Genular Protein ID: 3448540498

Symbol: SPCS2_HUMAN

Name: Signal peptidase complex subunit 2

UniProtKB Accession Codes:

Q15005 Q15507 Q3KQT0 Q641R4 Q6FG65 Q6IRX0 Q6P1P4 Q96HU9

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7788527

Title: Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7788527

DOI: 10.1093/dnares/2.1.37

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 34388369

Title: Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage.

PubMed ID: 34388369

DOI: 10.1016/j.molcel.2021.07.031

Sequence Information:

Length: 226
Mass: 25003
Checksum: C1EDF687E9F7A57A
Sequence:

MAAAAVQGGR SGGSGGCSGA GGASNCGTGS GRSGLLDKWK IDDKPVKIDK WDGSAVKNSL 
DDSAKKVLLE KYKYVENFGL IDGRLTICTI SCFFAIVALI WDYMHPFPES KPVLALCVIS 
YFVMMGILTI YTSYKEKSIF LVAHRKDPTG MDPDDIWQLS SSLKRFDDKY TLKLTFISGR 
TKQQREAEFT KSIAKFFDHS GTLVMDAYEP EISRLHDSLA IERKIK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SPCS2

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. PubMed ID: 7788527

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage. PubMed ID: 34388369