Details for: RB1CC1

Gene ID: 9821

Symbol: RB1CC1

Ensembl ID: ENSG00000023287

Description: RB1 inducible coiled-coil 1

Associated with

Other Information

Genular Protein ID: 3695733870

Symbol: RBCC1_HUMAN

Name: FAK family kinase-interacting protein of 200 kDa

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11850849

Title: Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells.

PubMed ID: 11850849

DOI: 10.1038/sj.onc.1205178

PubMed ID: 9039502

Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PubMed ID: 9039502

DOI: 10.1093/dnares/3.5.321

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10769033

Title: Suppression of Pyk2 kinase and cellular activities by FIP200.

PubMed ID: 10769033

DOI: 10.1083/jcb.149.2.423

PubMed ID: 12163359

Title: Preferential expression of RB1-inducible coiled-coil 1 in terminal differentiated musculoskeletal cells.

PubMed ID: 12163359

DOI: 10.1016/s0002-9440(10)64190-9

PubMed ID: 12095676

Title: Isolation, characterization and mapping of the mouse and human RB1CC1 genes.

PubMed ID: 12095676

DOI: 10.1016/s0378-1119(02)00585-1

PubMed ID: 12221124

Title: Regulation of focal adhesion kinase by a novel protein inhibitor FIP200.

PubMed ID: 12221124

DOI: 10.1091/mbc.e02-05-0295

PubMed ID: 12068296

Title: Truncating mutations of RB1CC1 in human breast cancer.

PubMed ID: 12068296

DOI: 10.1038/ng911

PubMed ID: 14533007

Title: RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells.

PubMed ID: 14533007

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19597335

Title: Atg101, a novel mammalian autophagy protein interacting with Atg13.

PubMed ID: 19597335

DOI: 10.4161/auto.5.7.9296

PubMed ID: 19211835

Title: Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

PubMed ID: 19211835

DOI: 10.1091/mbc.e08-12-1248

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21775823

Title: p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.

PubMed ID: 21775823

DOI: 10.4161/cc.10.16.16868

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23043107

Title: ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

PubMed ID: 23043107

DOI: 10.1074/jbc.m112.378109

PubMed ID: 23392225

Title: FIP200 regulates targeting of Atg16L1 to the isolation membrane.

PubMed ID: 23392225

DOI: 10.1038/embor.2013.6

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24954904

Title: WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.

PubMed ID: 24954904

DOI: 10.1016/j.molcel.2014.05.021

PubMed ID: 23289756

Title: The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy.

PubMed ID: 23289756

DOI: 10.1186/1471-2091-14-1

PubMed ID: 23262492

Title: Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

PubMed ID: 23262492

DOI: 10.1038/nsmb.2475

PubMed ID: 27334615

Title: The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.

PubMed ID: 27334615

DOI: 10.15252/embj.201694401

PubMed ID: 28890335

Title: The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.

PubMed ID: 28890335

DOI: 10.1016/j.molcel.2017.08.005

PubMed ID: 28561066

Title: WIPI3 and WIPI4 beta-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.

PubMed ID: 28561066

DOI: 10.1038/ncomms15637

PubMed ID: 31806350

Title: The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1.

PubMed ID: 31806350

DOI: 10.1016/j.molcel.2019.10.035

PubMed ID: 33226137

Title: Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

PubMed ID: 33226137

DOI: 10.15252/embj.2020104948

PubMed ID: 34471133

Title: Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation.

PubMed ID: 34471133

DOI: 10.1038/s41467-021-25572-w

PubMed ID: 33124732

Title: FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

PubMed ID: 33124732

DOI: 10.15252/embj.2019104369

PubMed ID: 17224074

Title: Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas.

PubMed ID: 17224074

DOI: 10.1186/bcr1637

Sequence Information:

  • Length: 1594
  • Mass: 183091
  • Checksum: C9C90A328875016A
  • Sequence:
  • MKLYVFLVNT GTTLTFDTEL TVQTVADLKH AIQSKYKIAI QHQVLVVNGG ECMAADRRVC 
    TYSAGTDTNP IFLFNKEMIL CDRPPAIPKT TFSTENDMEI KVEESLMMPA VFHTVASRTQ 
    LALEMYEVAK KLCSFCEGLV HDEHLQHQGW AAIMANLEDC SNSYQKLLFK FESIYSNYLQ 
    SIEDIKLKLT HLGTAVSVMA KIPLLECLTR HSYRECLGRL DSLPEHEDSE KAEMKRSTEL 
    VLSPDMPRTT NESLLTSFPK SVEHVSPDTA DAESGKEIRE SCQSTVHQQD ETTIDTKDGD 
    LPFFNVSLLD WINVQDRPND VESLVRKCFD SMSRLDPRII RPFIAECRQT IAKLDNQNMK 
    AIKGLEDRLY ALDQMIASCG RLVNEQKELA QGFLANQKRA ENLKDASVLP DLCLSHANQL 
    MIMLQNHRKL LDIKQKCTTA KQELANNLHV RLKWCCFVML HADQDGEKLQ ALLRLVIELL 
    ERVKIVEALS TVPQMYCLAV VEVVRRKMFI KHYREWAGAL VKDGKRLYEA EKSKRESFGK 
    LFRKSFLRNR LFRGLDSWPP SFCTQKPRKF DCELPDISLK DLQFLQSFCP SEVQPFLRVP 
    LLCDFEPLHQ HVLALHNLVK AAQSLDEMSQ TITDLLSEQK ASVSQTSPQS ASSPRMESTA 
    GITTTTSPRT PPPLTVQDPL CPAVCPLEEL SPDSIDAHTF DFETIPHPNI EQTIHQVSLD 
    LDSLAESPES DFMSAVNEFV IEENLSSPNP ISDPQSPEMM VESLYSSVIN AIDSRRMQDT 
    NVCGKEDFGD HTSLNVQLER CRVVAQDSHF SIQTIKEDLC HFRTFVQKEQ CDFSNSLKCT 
    AVEIRNIIEK VKCSLEITLK EKHQKELLSL KNEYEGKLDG LIKETEENEN KIKKLKGELV 
    CLEEVLQNKD NEFALVKHEK EAVICLQNEK DQKLLEMENI MHSQNCEIKE LKQSREIVLE 
    DLKKLHVEND EKLQLLRAEL QSLEQSHLKE LEDTLQVRHI QEFEKVMTDH RVSLEELKKE 
    NQQIINQIQE SHAEIIQEKE KQLQELKLKV SDLSDTRCKL EVELALKEAE TDEIKILLEE 
    SRAQQKETLK SLLEQETENL RTEISKLNQK IQDNNENYQV GLAELRTLMT IEKDQCISEL 
    ISRHEEESNI LKAELNKVTS LHNQAFEIEK NLKEQIIELQ SKLDSELSAL ERQKDEKITQ 
    QEEKYEAIIQ NLEKDRQKLV SSQEQDREQL IQKLNCEKDE AIQTALKEFK LEREVVEKEL 
    LEKVKHLENQ IAKSPAIDST RGDSSSLVAE LQEKLQEEKA KFLEQLEEQE KRKNEEMQNV 
    RTSLIAEQQT NFNTVLTREK MRKENIINDL SDKLKSTMQQ QERDKDLIES LSEDRARLLE 
    EKKKLEEEVS KLRSSSFVPS PYVATAPELY GACAPELPGE SDRSAVETAD EGRVDSAMET 
    SMMSVQENIH MLSEEKQRIM LLERTLQLKE EENKRLNQRL MSQSMSSVSS RHSEKIAIRD 
    FQVGDLVLII LDERHDNYVL FTVSPTLYFL HSESLPALDL KPGEGASGAS RRPWVLGKVM 
    EKEYCQAKKA QNRFKVPLGT KFYRVKAVSW NKKV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.