Details for: GINS1

Gene ID: 9837

Symbol: GINS1

Ensembl ID: ENSG00000101003

Description: GINS complex subunit 1

Associated with

Other Information

Genular Protein ID: 2789462595

Symbol: PSF1_HUMAN

Name: DNA replication complex GINS protein PSF1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8724849

Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8724849

DOI: 10.1093/dnares/3.1.17

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17611626

Title: Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression.

PubMed ID: 17611626

DOI: 10.1371/journal.pone.0000594

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 28414293

Title: Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.

PubMed ID: 28414293

DOI: 10.1172/jci90727

PubMed ID: 35585232

Title: Fast and efficient DNA replication with purified human proteins.

PubMed ID: 35585232

DOI: 10.1038/s41586-022-04759-1

PubMed ID: 17557111

Title: Molecular architecture of the human GINS complex.

PubMed ID: 17557111

DOI: 10.1038/sj.embor.7401002

PubMed ID: 17545466

Title: Crystal structure of the human GINS complex.

PubMed ID: 17545466

DOI: 10.1101/gad.1548107

PubMed ID: 17417653

Title: Structure of the human GINS complex and its assembly and functional interface in replication initiation.

PubMed ID: 17417653

DOI: 10.1038/nsmb1231

PubMed ID: 17652513

Title: Crystal structure of the GINS complex and functional insights into its role in DNA replication.

PubMed ID: 17652513

DOI: 10.1073/pnas.0705558104

PubMed ID: 32453425

Title: CryoEM structures of human CMG-ATPgammaS-DNA and CMG-AND-1 complexes.

PubMed ID: 32453425

DOI: 10.1093/nar/gkaa429

PubMed ID: 34694004

Title: Structure of a human replisome shows the organisation and interactions of a DNA replication machine.

PubMed ID: 34694004

DOI: 10.15252/embj.2021108819

PubMed ID: 34700328

Title: A conserved mechanism for regulating replisome disassembly in eukaryotes.

PubMed ID: 34700328

DOI: 10.1038/s41586-021-04145-3

Sequence Information:

  • Length: 196
  • Mass: 22988
  • Checksum: 2270B5CE6C43BFE5
  • Sequence:
  • MFCEKAMELI RELHRAPEGQ LPAFNEDGLR QVLEEMKALY EQNQSDVNEA KSGGRSDLIP 
    TIKFRHCSLL RNRRCTVAYL YDRLLRIRAL RWEYGSVLPN ALRFHMAAEE MEWFNNYKRS 
    LATYMRSLGG DEGLDITQDM KPPKSLYIEV RCLKDYGEFE VDDGTSVLLK KNSQHFLPRW 
    KCEQLIRQGV LEHILS

Genular Protein ID: 3024391297

Symbol: A0A8Q3WLK7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

Sequence Information:

  • Length: 161
  • Mass: 18906
  • Checksum: 358A00FBAD312C88
  • Sequence:
  • MKALYEQNQS DVNEAKSGGR SDLIPTIKFR HCSLLRNRRC TVAYLYDRLL RIRALRWEYG 
    SVLPNALRFH MAAEEMEWFN NYKRSLATYM RSLGGDEGLD ITQDMKPPKS LYIEVRCLKD 
    YGEFEVDDGT SVLLKKNSQH FLPRWKCEQL IRQGVLEHIL S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.