Details for: CDC5L
Associated with
Other Information
Genular Protein ID: 4214608898
Symbol: CDC5L_HUMAN
Name: Cell division cycle 5-like protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9038199
Title: Pombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signaling.
PubMed ID: 9038199
PubMed ID: 9598309
Title: Rearrangement of the human CDC5L gene by a t(6;19)(p21;q13.1) in a patient with multicystic renal dysplasia.
PubMed ID: 9598309
PubMed ID: 9632794
Title: Myb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes.
PubMed ID: 9632794
PubMed ID: 9455477
Title: Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9455477
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8917598
Title: A cdc5+ homolog of a higher plant, Arabidopsis thaliana.
PubMed ID: 8917598
PubMed ID: 10827081
Title: NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry.
PubMed ID: 10827081
PubMed ID: 9468527
Title: A mammalian homolog of fission yeast Cdc5 regulates G2 progression and mitotic entry.
PubMed ID: 9468527
PubMed ID: 9731529
Title: Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.
PubMed ID: 9731529
DOI: 10.1038/1700
PubMed ID: 10570151
Title: Evidence that Myb-related CDC5 proteins are required for pre-mRNA splicing.
PubMed ID: 10570151
PubMed ID: 11101529
Title: Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.
PubMed ID: 11101529
PubMed ID: 11082045
Title: Human Cdc5, a regulator of mitotic entry, can act as a site-specific DNA binding protein.
PubMed ID: 11082045
PubMed ID: 11544257
Title: A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing.
PubMed ID: 11544257
PubMed ID: 11991638
Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
PubMed ID: 11991638
PubMed ID: 12927788
Title: hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.
PubMed ID: 12927788
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18583928
Title: Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing.
PubMed ID: 18583928
DOI: 10.4161/cc.7.12.6017
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18722174
Title: Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1.
PubMed ID: 18722174
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20176811
Title: Molecular architecture of the human Prp19/CDC5L complex.
PubMed ID: 20176811
DOI: 10.1128/mcb.01505-09
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21385873
Title: CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31.
PubMed ID: 21385873
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23022480
Title: Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA.
PubMed ID: 23022480
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24332808
Title: PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
PubMed ID: 24332808
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 32484799
Title: Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID.
PubMed ID: 32484799
DOI: 10.1172/jci131297
PubMed ID: 28502770
Title: An Atomic Structure of the Human Spliceosome.
PubMed ID: 28502770
PubMed ID: 28076346
Title: Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
PubMed ID: 28076346
DOI: 10.1038/nature21079
PubMed ID: 29361316
Title: Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex.
PubMed ID: 29361316
PubMed ID: 29360106
Title: Structure of the human activated spliceosome in three conformational states.
PubMed ID: 29360106
DOI: 10.1038/cr.2018.14
PubMed ID: 29301961
Title: Structure of a human catalytic step I spliceosome.
PubMed ID: 29301961
PubMed ID: 30728453
Title: Structures of the human spliceosomes before and after release of the ligated exon.
PubMed ID: 30728453
PubMed ID: 30705154
Title: A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
PubMed ID: 30705154
PubMed ID: 33509932
Title: Structure of the activated human minor spliceosome.
PubMed ID: 33509932
Sequence Information:
- Length: 802
- Mass: 92251
- Checksum: 3390F91EE7E79DA6
- Sequence:
MPRIMIKGGV WRNTEDEILK AAVMKYGKNQ WSRIASLLHR KSAKQCKARW YEWLDPSIKK TEWSREEEEK LLHLAKLMPT QWRTIAPIIG RTAAQCLEHY EFLLDKAAQR DNEEETTDDP RKLKPGEIDP NPETKPARPD PIDMDEDELE MLSEARARLA NTQGKKAKRK AREKQLEEAR RLAALQKRRE LRAAGIEIQK KRKRKRGVDY NAEIPFEKKP ALGFYDTSEE NYQALDADFR KLRQQDLDGE LRSEKEGRDR KKDKQHLKRK KESDLPSAIL QTSGVSEFTK KRSKLVLPAP QISDAELQEV VKVGQASEIA RQTAEESGIT NSASSTLLSE YNVTNNSVAL RTPRTPASQD RILQEAQNLM ALTNVDTPLK GGLNTPLHES DFSGVTPQRQ VVQTPNTVLS TPFRTPSNGA EGLTPRSGTT PKPVINSTPG RTPLRDKLNI NPEDGMADYS DPSYVKQMER ESREHLRLGL LGLPAPKNDF EIVLPENAEK ELEEREIDDT YIEDAADVDA RKQAIRDAER VKEMKRMHKA VQKDLPRPSE VNETILRPLN VEPPLTDLQK SEELIKKEMI TMLHYDLLHH PYEPSGNKKG KTVGFGTNNS EHITYLEHNP YEKFSKEELK KAQDVLVQEM EVVKQGMSHG ELSSEAYNQV WEECYSQVLY LPGQSRYTRA NLASKKDRIE SLEKRLEINR GHMTTEAKRA AKMEKKMKIL LGGYQSRAMG LMKQLNDLWD QIEQAHLELR TFEELKKHED SAIPRRLECL KEDVQRQQER EKELQHRYAD LLLEKETLKS KF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.