Genular: Defining Cellular Identity and Function

Details for: POM121

Gene ID: 9883

Symbol: POM121

Ensembl ID: ENSG00000196313

Description: POM121 transmembrane nucleoporin

Associated with

Antiviral mechanism by ifn-stimulated genes
(R-HSA-1169410)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to heat stress
(R-HSA-3371556)
Cytokine signaling in immune system
(R-HSA-1280215)
Defective tpr may confer susceptibility towards thyroid papillary carcinoma (tpc)
(R-HSA-5619107)
Disease
(R-HSA-1643685)
Disorders of transmembrane transporters
(R-HSA-5619115)
Export of viral ribonucleoproteins from nucleus
(R-HSA-168274)
Gene expression (transcription)
(R-HSA-74160)
Gene silencing by rna
(R-HSA-211000)
Glucose metabolism
(R-HSA-70326)
Glycolysis
(R-HSA-70171)
Hcmv early events
(R-HSA-9609690)
Hcmv infection
(R-HSA-9609646)
Hcmv late events
(R-HSA-9610379)
Hiv infection
(R-HSA-162906)
Hiv life cycle
(R-HSA-162587)
Host interactions of hiv factors
(R-HSA-162909)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
Interactions of rev with host cellular proteins
(R-HSA-177243)
Interactions of vpr with host cellular proteins
(R-HSA-176033)
Interferon signaling
(R-HSA-913531)
Isg15 antiviral mechanism
(R-HSA-1169408)
Late phase of hiv life cycle
(R-HSA-162599)
Metabolism
(R-HSA-1430728)
Metabolism of carbohydrates
(R-HSA-71387)
Metabolism of non-coding rna
(R-HSA-194441)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Mitotic anaphase
(R-HSA-68882)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prophase
(R-HSA-68875)
M phase
(R-HSA-68886)
Nep/ns2 interacts with the cellular export machinery
(R-HSA-168333)
Ns1 mediated effects on host pathways
(R-HSA-168276)
Nuclear envelope (ne) reassembly
(R-HSA-2995410)
Nuclear envelope breakdown
(R-HSA-2980766)
Nuclear import of rev protein
(R-HSA-180746)
Nuclear pore complex (npc) disassembly
(R-HSA-3301854)
Post-translational protein modification
(R-HSA-597592)
Postmitotic nuclear pore complex (npc) reformation
(R-HSA-9615933)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Regulation of glucokinase by glucokinase regulatory protein
(R-HSA-170822)
Regulation of hsf1-mediated heat shock response
(R-HSA-3371453)
Rev-mediated nuclear export of hiv rna
(R-HSA-165054)
Sars-cov-2 activates/modulates innate and adaptive immune responses
(R-HSA-9705671)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov-2-host interactions
(R-HSA-9705683)
Sars-cov infections
(R-HSA-9679506)
Slc transporter disorders
(R-HSA-5619102)
Snrnp assembly
(R-HSA-191859)
Sumo e3 ligases sumoylate target proteins
(R-HSA-3108232)
Sumoylation
(R-HSA-2990846)
Sumoylation of chromatin organization proteins
(R-HSA-4551638)
Sumoylation of dna damage response and repair proteins
(R-HSA-3108214)
Sumoylation of dna replication proteins
(R-HSA-4615885)
Sumoylation of rna binding proteins
(R-HSA-4570464)
Sumoylation of sumoylation proteins
(R-HSA-4085377)
Sumoylation of ubiquitinylation proteins
(R-HSA-3232142)
Transcriptional regulation by small rnas
(R-HSA-5578749)
Transport of mature mrna derived from an intron-containing transcript
(R-HSA-159236)
Transport of mature mrna derived from an intronless transcript
(R-HSA-159231)
Transport of mature mrnas derived from intronless transcripts
(R-HSA-159234)
Transport of mature transcript to cytoplasm
(R-HSA-72202)
Transport of ribonucleoproteins into the host nucleus
(R-HSA-168271)
Transport of the slbp dependant mature mrna
(R-HSA-159230)
Transport of the slbp independent mature mrna
(R-HSA-159227)
Trna processing
(R-HSA-72306)
Trna processing in the nucleus
(R-HSA-6784531)
Viral infection pathways
(R-HSA-9824446)
Viral messenger rna synthesis
(R-HSA-168325)
Vpr-mediated nuclear import of pics
(R-HSA-180910)
Endoplasmic reticulum membrane
(GO:0005789)
Mrna transport
(GO:0051028)
Nuclear envelope
(GO:0005635)
Nuclear localization sequence binding
(GO:0008139)
Nuclear membrane
(GO:0031965)
Nuclear pore
(GO:0005643)
Nucleocytoplasmic transport
(GO:0006913)
Nucleoplasm
(GO:0005654)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Rna export from nucleus
(GO:0006405)
Structural constituent of nuclear pore
(GO:0017056)

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 3.81
Marker Score: 50,689
Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 2.62
Marker Score: 1,272
Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.81
Marker Score: 2,189
Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.77
Marker Score: 65,178
Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.71
Marker Score: 7,089
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.65
Marker Score: 101,679
Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.63
Marker Score: 15,462
Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.6
Marker Score: 15,054
Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.6
Marker Score: 2,149
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.6
Marker Score: 13,703
Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.58
Marker Score: 23,558
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.55
Marker Score: 6,475
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.53
Marker Score: 3,365
Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.53
Marker Score: 30,411
Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.51
Marker Score: 5,826
Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.5
Marker Score: 57,026
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.46
Marker Score: 2,260
Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.45
Marker Score: 585
Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.41
Marker Score: 10,787
Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.4
Marker Score: 816
Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.38
Marker Score: 804
Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.35
Marker Score: 1,550
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.34
Marker Score: 1,483
Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.33
Marker Score: 28,286
Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.28
Marker Score: 2,148
Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.24
Marker Score: 5,728
Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.22
Marker Score: 513
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.22
Marker Score: 386
Cell Name: germ cell (CL0000586)
Fold Change: 1.21
Marker Score: 2,108
Cell Name: fat cell (CL0000136)
Fold Change: 1.12
Marker Score: 628
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.12
Marker Score: 1,645
Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.11
Marker Score: 24,825
Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.11
Marker Score: 3,015
Cell Name: interneuron (CL0000099)
Fold Change: 1.1
Marker Score: 504
Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.1
Marker Score: 2,121
Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.1
Marker Score: 1,188
Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.06
Marker Score: 6,821
Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.06
Marker Score: 3,752
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.05
Marker Score: 1,104
Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.04
Marker Score: 4,492
Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.02
Marker Score: 2,404
Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.02
Marker Score: 1,266
Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 1.01
Marker Score: 371
Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.01
Marker Score: 602
Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,678
Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,903
Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.99
Marker Score: 312
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.98
Marker Score: 15,393
Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,390
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.97
Marker Score: 32,976
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.97
Marker Score: 283
Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.96
Marker Score: 2,741
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.96
Marker Score: 855
Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.95
Marker Score: 260
Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.94
Marker Score: 5,067
Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,394
Cell Name: proerythroblast (CL0000547)
Fold Change: 0.93
Marker Score: 629
Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.93
Marker Score: 267
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 476
Cell Name: classical monocyte (CL0000860)
Fold Change: 0.92
Marker Score: 3,816
Cell Name: granulosa cell (CL0000501)
Fold Change: 0.92
Marker Score: 9,233
Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 432
Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,697
Cell Name: renal principal cell (CL0005009)
Fold Change: 0.9
Marker Score: 690
Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.89
Marker Score: 337
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,293
Cell Name: podocyte (CL0000653)
Fold Change: 0.87
Marker Score: 322
Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.87
Marker Score: 325
Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.86
Marker Score: 372
Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.86
Marker Score: 453
Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.85
Marker Score: 723
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306
Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.84
Marker Score: 803
Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.84
Marker Score: 4,801
Cell Name: Unknown (CL0002371)
Fold Change: 0.84
Marker Score: 891
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.84
Marker Score: 950
Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.84
Marker Score: 220
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.83
Marker Score: 282
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.82
Marker Score: 1,335
Cell Name: Schwann cell (CL0002573)
Fold Change: 0.82
Marker Score: 285
Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.82
Marker Score: 1,154
Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.81
Marker Score: 295
Cell Name: Leydig cell (CL0000178)
Fold Change: 0.81
Marker Score: 869
Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.8
Marker Score: 455
Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.8
Marker Score: 991
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.79
Marker Score: 823
Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.79
Marker Score: 240
Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.79
Marker Score: 523
Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.79
Marker Score: 391
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.78
Marker Score: 313
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.78
Marker Score: 833
Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 577
Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.75
Marker Score: 686
Cell Name: melanocyte (CL0000148)
Fold Change: 0.75
Marker Score: 302
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.74
Marker Score: 1,681
Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.73
Marker Score: 411
Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 372
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: 0.72
Marker Score: 399
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.71
Marker Score: 2,963
Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.7
Marker Score: 1,722

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

**Key Characteristics** POM121 is a transmembrane protein with a unique structure, consisting of a transmembrane domain and a nucleoporin domain. The nucleoporin domain is responsible for binding to nuclear import receptors and facilitating the transport of proteins and RNAs across the nuclear envelope. POM121 is also involved in the regulation of gene expression, particularly in the context of interferon-stimulated genes (ISGs) and viral infections. The protein's expression is tightly regulated, and its dysregulation has been implicated in various diseases, including thyroid papillary carcinoma. **Pathways and Functions** POM121 plays a critical role in various cellular processes, including: 1. **Nuclear Import and Export**: POM121 facilitates the transport of proteins and RNAs across the nuclear envelope, regulating gene expression and cell cycle progression. 2. **Interferon Signaling**: POM121 is involved in the regulation of ISGs, which are crucial for the host's antiviral response to viral infections. 3. **Viral Infection**: POM121 interacts with viral proteins, such as Vpr and Rev, to facilitate viral entry and replication. 4. **Cellular Stress Response**: POM121 is involved in the regulation of cellular responses to stress and stimuli, including heat shock and cytokine signaling. 5. **RNA Transport**: POM121 regulates the transport of RNAs, including mRNA and tRNA, from the nucleus to the cytoplasm. **Clinical Significance** Dysregulation of POM121 has been implicated in various diseases, including: 1. **Thyroid Papillary Carcinoma**: Mutations in the POM121 gene have been associated with an increased risk of thyroid papillary carcinoma. 2. **Viral Infections**: POM121 plays a critical role in the regulation of viral infections, including HIV, HCMV, and SARS-CoV-2. 3. **Neurodegenerative Diseases**: POM121 has been implicated in the regulation of gene expression in neurons, and its dysregulation may contribute to neurodegenerative diseases, such as Alzheimer's and Parkinson's. 4. **Cancer**: POM121 is overexpressed in various types of cancer, including breast, lung, and colon cancer, and its dysregulation may contribute to tumorigenesis. In conclusion, POM121 is a critical protein that plays a central role in various cellular processes, including nuclear import and export, interferon signaling, viral infection, and cellular stress response. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the function and regulation of POM121 in the context of human health and disease.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Nuclear envelope pore membrane protein POM 121

Genular Protein ID: 3266137341

Symbol: P121A_HUMAN

Name: Nuclear envelope pore membrane protein POM 121

UniProtKB Accession Codes:

Q96HA1 A6NFS9 A8CDT4 A8K933 A8MXF9 O75115 Q96DI0 Q9H9X1 Q9Y2N3 Q9Y4S7

Database IDs:

Citations:

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17900573

Title: Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

PubMed ID: 17900573

DOI: 10.1016/j.febslet.2007.09.021

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

Length: 1249
Mass: 127720
Checksum: EDBA86CA5D658F61
Sequence:

MSPAAAAAGA GERRRPIASV RDGRGRGCGG PARAVLLGLS LVGLLLYLVP AAAALAWLTV 
GATAAWWGLS REPRGSRPLS SFVRKARHRR PLSSFVRKAR HRRTLFASPL AKSTANGNLL 
EPRTLLEGPD PAELLLMGSY LGKPGPPQPA AAPEGQDLRD RPGRRPPARP APRSPPPRSP 
PPRSPPPSPP THRAHHVYPS LPTPLLRPSR RPSPRDCGTL PNRFVITPRR RYPIHQAQYS 
CLGVLPTVCW NGYHKKAVLS PRNSRMVCSP VTVRIAPPDR RFSRSAIPEQ IISSTLSSPS 
SNAPDPCAKE TVLSALKEKE KKRTVEEEDQ IFLDGQENKR RRHDSSGSGH SAFEPLVANG 
VPASFVPKPG SLKRGLNSQS SDDHLNKRSR SSSMSSLTGA YASGIPSSSR NAITSSYSST 
RGISQLWKRN GPSSSPFSSP ASSRSQTPER PAKKIREEEL CHHSSSSTPL AADRESQGEK 
AADTTPRKKQ NSNSQSTPGS SGQRKRKVQL LPSRRGEQLT LPPPPQLGYS ITAEDLDLEK 
KASLQWFNQA LEDKSDAASN SVTETPPITQ PSFTFTLPAA APASPPTSLL APSTNPLLES 
LKKMQTPPSL PPCPESAGAA TTEALSPPKT PSLLPPLGLS QSGPPGLLPS PSFDSKPPTT 
LLGLIPAPSM VPATDTKAPP TLQAETATKP QATSAPSPAP KQSFLFGTQN TSPSSPAAPA 
ASSAPPMFKP IFTAPPKSEK EGPTPPGPSV TATAPSSSSL PTTTSTTAPT FQPVFSSMGP 
PASVPLPAPF FKQTTTPATA PTTTAPLFTG LASATSAVAP ITSASPSTDS ASKPAFGFGI 
NSVSSSSVST TTSTATAASQ PFLFGAPQAS AASFTPAMGS IFQFGKPPAL PTTTTVTTFS 
QSLHTAVPTA TSSSAADFSG FGSTLATSAP ATSSQPTLTF SNTSTPTFNI PFGSSAKSPL 
PSYPGANPQP AFGAAEGQPP GAAKPALAPS FGSSFTFGNS AAPAAAPTPA PPSMIKVVPA 
YVPTPIHPIF GGATHSAFGL KATASAFGAP ASSQPAFGGS TAVFFGAATS SGFGATTQTA 
SSGSSSSVFG STTPSPFTFG GSAAPAGSGS FGINVATPGS STTTGAFSFG AGQSGSTATS 
TPFAGGLGQN ALGTTGQSTP FAFNVSSTTE SKPVFGGTAT PTFGLNTPAP GVGTSGSSLS 
FGASSAPAQG FVGVAPFGSA ALSFSIGAGS KTPGARQRLQ ARRQHTRKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: POM121

Associated with

Cells (max top 100)

Other Information

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. PubMed ID: 9734811

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes. PubMed ID: 17900573

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163