Details for: SEPTIN7

Gene ID: 989

Symbol: SEPTIN7

Ensembl ID: ENSG00000122545

Description: septin 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 803.0462
    Cell Significance Index: -124.9100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 482.7250
    Cell Significance Index: -122.4400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 351.2825
    Cell Significance Index: -144.7100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 305.1023
    Cell Significance Index: -123.9500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 301.7224
    Cell Significance Index: -142.4500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 267.7760
    Cell Significance Index: -137.7400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 213.4654
    Cell Significance Index: -143.2400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 131.6009
    Cell Significance Index: -125.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 113.7592
    Cell Significance Index: -140.2600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 48.4331
    Cell Significance Index: -148.7600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 36.7583
    Cell Significance Index: -145.0500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 28.1597
    Cell Significance Index: -61.6300
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 8.1245
    Cell Significance Index: 37.5100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 5.5676
    Cell Significance Index: 86.1400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 4.9131
    Cell Significance Index: 257.9600
  • Cell Name: theca cell (CL0000503)
    Fold Change: 3.8740
    Cell Significance Index: 22.7600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.5638
    Cell Significance Index: 219.0500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.3760
    Cell Significance Index: 463.6200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.6635
    Cell Significance Index: 534.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.6513
    Cell Significance Index: 326.0100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.5475
    Cell Significance Index: 66.9900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.4653
    Cell Significance Index: 159.0500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.3505
    Cell Significance Index: 423.7200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.2185
    Cell Significance Index: 115.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.0133
    Cell Significance Index: 237.4300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.0035
    Cell Significance Index: 718.6300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.9482
    Cell Significance Index: 249.7500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.7012
    Cell Significance Index: 40.8000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.6627
    Cell Significance Index: 908.0500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.4553
    Cell Significance Index: 50.5700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4365
    Cell Significance Index: 1297.0700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3199
    Cell Significance Index: 214.6700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.3092
    Cell Significance Index: 578.8300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.2902
    Cell Significance Index: 36.9900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1343
    Cell Significance Index: 63.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9963
    Cell Significance Index: 197.7200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.6325
    Cell Significance Index: 13.2400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.5885
    Cell Significance Index: 29.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4559
    Cell Significance Index: 45.1000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.4324
    Cell Significance Index: 7.4100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3583
    Cell Significance Index: 16.8400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.3088
    Cell Significance Index: 2.3800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2672
    Cell Significance Index: 5.8500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1029
    Cell Significance Index: 193.7500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1023
    Cell Significance Index: 7.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0827
    Cell Significance Index: 52.5500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.0775
    Cell Significance Index: 0.8800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0026
    Cell Significance Index: -4.7300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0045
    Cell Significance Index: -6.8900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0081
    Cell Significance Index: -0.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0423
    Cell Significance Index: -1.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0432
    Cell Significance Index: -1.9600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0465
    Cell Significance Index: -21.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0548
    Cell Significance Index: -40.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0596
    Cell Significance Index: -81.0600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0647
    Cell Significance Index: -8.3600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0757
    Cell Significance Index: -5.6400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0761
    Cell Significance Index: -57.5800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0886
    Cell Significance Index: -5.3200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1436
    Cell Significance Index: -106.3900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2385
    Cell Significance Index: -24.3600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2421
    Cell Significance Index: -17.1200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2495
    Cell Significance Index: -140.7300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2579
    Cell Significance Index: -161.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.2787
    Cell Significance Index: -53.0400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3822
    Cell Significance Index: -25.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4332
    Cell Significance Index: -62.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4523
    Cell Significance Index: -130.1500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5616
    Cell Significance Index: -64.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5841
    Cell Significance Index: -15.9000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.5902
    Cell Significance Index: -100.7900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6837
    Cell Significance Index: -20.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.7470
    Cell Significance Index: -157.3400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.7685
    Cell Significance Index: -13.5800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7897
    Cell Significance Index: -49.7700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.8430
    Cell Significance Index: -23.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.8657
    Cell Significance Index: -30.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.9928
    Cell Significance Index: -115.7000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.0049
    Cell Significance Index: -52.2000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.0402
    Cell Significance Index: -48.5000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -1.0852
    Cell Significance Index: -21.1800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.1243
    Cell Significance Index: -15.3400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.2443
    Cell Significance Index: -35.8500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.2632
    Cell Significance Index: -131.5300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.4161
    Cell Significance Index: -37.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.4465
    Cell Significance Index: -114.5600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.5317
    Cell Significance Index: -39.1300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.5359
    Cell Significance Index: -19.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.5480
    Cell Significance Index: -68.4700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -1.5746
    Cell Significance Index: -20.1700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -1.6277
    Cell Significance Index: -66.7000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.7012
    Cell Significance Index: -36.8600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.9113
    Cell Significance Index: -40.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.9614
    Cell Significance Index: -74.2700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -2.0310
    Cell Significance Index: -17.0600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -2.0391
    Cell Significance Index: -58.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.0422
    Cell Significance Index: -125.2100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -2.3352
    Cell Significance Index: -43.1600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -2.3933
    Cell Significance Index: -14.4600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -2.7964
    Cell Significance Index: -71.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SEPT7 exhibits several key characteristics that define its function and regulation: 1. **GTP-binding properties**: SEPT7 belongs to the septin family, which is characterized by its ability to bind GTP (guanosine triphosphate). This interaction is essential for its function in regulating cellular processes. 2. **Cytoskeletal organization**: SEPT7 interacts with various cytoskeletal proteins, including microtubules and actin filaments, to maintain cytoskeletal organization and dynamics. 3. **Cell cycle regulation**: SEPT7 is involved in regulating the cell cycle, particularly in the G2/M phase, where it helps to ensure proper chromosome segregation and cytokinesis. 4. **Signal transduction**: SEPT7 interacts with various signaling molecules, including MAPK kinases, to regulate signal transduction pathways involved in cell proliferation, differentiation, and migration. **Pathways and Functions** SEPT7 is involved in various cellular processes, including: 1. **Cytoskeleton-dependent cytokinesis**: SEPT7 regulates the formation of the cleavage furrow, a structure critical for cytokinesis, the process by which a cell divides into two daughter cells. 2. **Cell differentiation**: SEPT7 is involved in regulating cell differentiation, particularly in the development of immune cells, epithelial cells, and muscle cells. 3. **Signal transduction**: SEPT7 interacts with various signaling molecules to regulate signal transduction pathways involved in cell proliferation, differentiation, and migration. 4. **Embryonic cell shape regulation**: SEPT7 helps to regulate embryonic cell shape and morphogenesis, particularly in the development of the nervous system and immune system. **Clinical Significance** SEPT7 has been implicated in various diseases and disorders, including: 1. **Immune-related disorders**: SEPT7 expression is altered in immune cells, particularly in conditions involving immune cell dysfunction, such as autoimmune diseases and cancer. 2. **Cancer**: SEPT7 is overexpressed in various types of cancer, including breast, lung, and colon cancer, where it may contribute to tumor progression and metastasis. 3. **Neurological disorders**: SEPT7 expression is altered in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may contribute to neuronal dysfunction and degeneration. In conclusion, SEPT7 is a multifunctional protein that plays critical roles in various cellular processes, including cell division, cytoskeleton organization, and signal transduction. Its expression is altered in various diseases and disorders, highlighting the importance of SEPT7 in maintaining cellular homeostasis and promoting tissue health. Further research is needed to fully elucidate the functions and clinical significance of SEPT7.

Genular Protein ID: 3018259232

Symbol: SEPT7_HUMAN

Name: Septin-7

UniProtKB Accession Codes:

Q16181 Q52M76 Q6NX50

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 6 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 EMDB 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SASBDB 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8037772

Title: Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae.

PubMed ID: 8037772

DOI: 10.1006/bbrc.1994.1896

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15485874

Title: Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.

PubMed ID: 15485874

DOI: 10.1074/jbc.m406153200

PubMed ID: 15915442

Title: Expression profiling the human septin gene family.

PubMed ID: 15915442

DOI: 10.1002/path.1789

PubMed ID: 16093351

Title: Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4.

PubMed ID: 16093351

DOI: 10.1091/mbc.e05-03-0267

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16914550

Title: Structural analysis of septin 2, 6, and 7 complexes.

PubMed ID: 16914550

DOI: 10.1074/jbc.m605179200

PubMed ID: 17803907

Title: Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

PubMed ID: 17803907

DOI: 10.1016/j.cell.2007.06.053

PubMed ID: 18460473

Title: Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization.

PubMed ID: 18460473

DOI: 10.1074/jbc.m710591200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19145258

Title: Septins regulate bacterial entry into host cells.

PubMed ID: 19145258

DOI: 10.1371/journal.pone.0004196

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25588830

Title: SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octomeric complexes with other SEPT proteins.

PubMed ID: 25588830

DOI: 10.1242/jcs.158998

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 17637674

Title: Structural insight into filament formation by mammalian septins.

PubMed ID: 17637674

DOI: 10.1038/nature06052

Sequence Information:

  • Length: 437
  • Mass: 50680
  • Checksum: 946A08C54B7124FF
  • Sequence:
    • MSVSARSAAA EERSVNSSTM VAQQKNLEGY VGFANLPNQV YRKSVKRGFE FTLMVVGESG 
LGKSTLINSL FLTDLYSPEY PGPSHRIKKT VQVEQSKVLI KEGGVQLLLT IVDTPGFGDA 
VDNSNCWQPV IDYIDSKFED YLNAESRVNR RQMPDNRVQC CLYFIAPSGH GLKPLDIEFM 
KRLHEKVNII PLIAKADTLT PEECQQFKKQ IMKEIQEHKI KIYEFPETDD EEENKLVKKI 
KDRLPLAVVG SNTIIEVNGK RVRGRQYPWG VAEVENGEHC DFTILRNMLI RTHMQDLKDV 
TNNVHYENYR SRKLAAVTYN GVDNNKNKGQ LTKSPLAQME EERREHVAKM KKMEMEMEQV 
FEMKVKEKVQ KLKDSEAELQ RRHEQMKKNL EAQHKELEEK RRQFEDEKAN WEAQQRILEQ 
QNSSRTLEKN KKKGKIF

Genular Protein ID: 3191608957

Symbol: B4DNE4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DNE4

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 12 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 382
  • Mass: 44644
  • Checksum: 1F183832F7A22DA9
  • Sequence:
    • MGESGLGKST LINSLFLTDL YSPEYPGPSH RIKKTVQVEQ SKVLIKEGGV QLLLTIVDTP 
GFGDAVDNSN CWQPVIDYID SKFEDYLNAE SRVNRRQMPD NRVQCCLYFI APSGHGLKPL 
DIEFMKRLHE KVNIIPLIAK ADTLTPEECQ QFKKQIMKEI QEHKIKIYEF PETDDEEENK 
LVKKIKDRLP LAVVGSNTII EVNGKRVRGR QYPWGVAEVE NGEHCDFTIL RNMLIRTHMQ 
DLKDVTNNVH YENYRSRKLA AVTYNGVDNN KNKGQLTKSP LAQMEEERRE HVAKMKKMEM 
EMEQVFEMKV KEKVQKLKDS EAELQRRHEQ MKKNLEAQHK ELEEKRRQFE DEKANWEAQQ 
RILEQQNSSR TLEKNKKKGK IF

Genular Protein ID: 1636037073

Symbol: A8K3D0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K3D0

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 12 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1 iPTMnet 1

Sequence Information:

  • Length: 436
  • Mass: 50509
  • Checksum: 8030F08F60C173DB
  • Sequence:
    • MSVSARSAAA EERSVNSSTM AQQKNLEGYV GFANLPNQVY RKSVKRGFEF TLMVVGESGL 
GKSTLINSLF LTDLYSPEYP GPSHRIKKTV QVEQSKVLIK EGGVQLLLTI VDTPGFGDAV 
DNSNCWQPVI DYIDSKFEDY LNAESRVNRR QMPDNRVQCC LYFIAPSGHG LKPLDIEFMK 
RLHEKVNIIP LIAKADTLTP EECQQFKKQI MKEIQEHKIK IYEFPETDDE EENKLVKKIK 
DRLPLAVVGS NTIIEVNGKR VRGRQYPWGV AEVENGEHCD FTILRNMLIR THMQDLKDVT 
NNVHYENYRS RKLAAVTYNG VDNNKNKGQL TKSPLAQMEE ERREHVAKMK KMEMGMEQVF 
EMKVKEKVQK LKDSEAELQR RHEQMKKNLE AQHKELEEKR RQFEDEKANW EAQQRILEQQ 
NSSRTLEKNK KKGKIF

Genular Protein ID: 1993019917

Symbol: G3V1Q4_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3V1Q4

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 401
  • Mass: 46566
  • Checksum: 3B79676A684FE210
  • Sequence:
    • MSVSARSAAA EERSVNSSTM GESGLGKSTL INSLFLTDLY SPEYPGPSHR IKKTVQVEQS 
KVLIKEGGVQ LLLTIVDTPG FGDAVDNSNC WQPVIDYIDS KFEDYLNAES RVNRRQMPDN 
RVQCCLYFIA PSGHGLKPLD IEFMKRLHEK VNIIPLIAKA DTLTPEECQQ FKKQIMKEIQ 
EHKIKIYEFP ETDDEEENKL VKKIKDRLPL AVVGSNTIIE VNGKRVRGRQ YPWGVAEVEN 
GEHCDFTILR NMLIRTHMQD LKDVTNNVHY ENYRSRKLAA VTYNGVDNNK NKGQLTKSPL 
AQMEEERREH VAKMKKMEME MEQVFEMKVK EKVQKLKDSE AELQRRHEQM KKNLEAQHKE 
LEEKRRQFED EKANWEAQQR ILEQQNSSRT LEKNKKKGKI F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.