Details for: SEPTIN7

Gene ID: 989

Symbol: SEPTIN7

Ensembl ID: ENSG00000122545

Description: septin 7

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 12.95
    Marker Score: 13,005
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 5.77
    Marker Score: 3,381
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 5.05
    Marker Score: 3,697
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 4.88
    Marker Score: 5,287
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 4.73
    Marker Score: 1,387
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 4.59
    Marker Score: 10,995
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 4.51
    Marker Score: 4,683
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 4.3
    Marker Score: 3,031
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 4.23
    Marker Score: 3,594
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 4.21
    Marker Score: 2,819
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 3.88
    Marker Score: 51,576
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.78
    Marker Score: 37,478
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 3.66
    Marker Score: 3,491
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 3.64
    Marker Score: 10,046
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 3.61
    Marker Score: 6,779
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 3.59
    Marker Score: 47,391
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.52
    Marker Score: 4,246
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 3.5
    Marker Score: 47,085
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 3.48
    Marker Score: 3,872
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 3.45
    Marker Score: 10,882
  • Cell Name: theca cell (CL0000503)
    Fold Change: 3.44
    Marker Score: 2,464
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 3.4
    Marker Score: 9,927
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 3.31
    Marker Score: 3,125
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 3.3
    Marker Score: 2,946
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 3.27
    Marker Score: 2,174
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 3.26
    Marker Score: 638
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 3.24
    Marker Score: 9,099
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.24
    Marker Score: 37,606
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 3.23
    Marker Score: 3,121
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 3.22
    Marker Score: 1,188
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 3.22
    Marker Score: 2,118
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.21
    Marker Score: 109,305
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 3.19
    Marker Score: 1,761
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 3.18
    Marker Score: 1,774
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 3.17
    Marker Score: 2,159
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 3.15
    Marker Score: 4,099
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 3.13
    Marker Score: 1,780
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 3.09
    Marker Score: 4,289
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 3.07
    Marker Score: 6,246
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 3.05
    Marker Score: 4,495
  • Cell Name: T-helper 1 cell (CL0000545)
    Fold Change: 3.04
    Marker Score: 1,185
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 3.03
    Marker Score: 1,306
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 3.03
    Marker Score: 2,153
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 3.01
    Marker Score: 2,966
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.98
    Marker Score: 2,619
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 2.98
    Marker Score: 4,590
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 2.95
    Marker Score: 4,053
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 2.92
    Marker Score: 6,127
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.89
    Marker Score: 4,895
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.88
    Marker Score: 4,075
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 2.85
    Marker Score: 3,445
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 2.84
    Marker Score: 911
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 2.83
    Marker Score: 932
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 2.83
    Marker Score: 6,905
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 2.83
    Marker Score: 1,069
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.81
    Marker Score: 1,590
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.81
    Marker Score: 2,202
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.8
    Marker Score: 59,830
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.79
    Marker Score: 18,158
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 2.79
    Marker Score: 2,025
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 2.79
    Marker Score: 1,484
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.78
    Marker Score: 665
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.76
    Marker Score: 2,948
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 2.75
    Marker Score: 3,797
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 2.75
    Marker Score: 7,199
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.75
    Marker Score: 12,710
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.72
    Marker Score: 144,005
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.72
    Marker Score: 2,290
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 2.71
    Marker Score: 2,488
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.71
    Marker Score: 1,699
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.7
    Marker Score: 2,045
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.69
    Marker Score: 1,959
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.67
    Marker Score: 2,019
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.65
    Marker Score: 2,494
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2.64
    Marker Score: 4,816
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 2.64
    Marker Score: 858
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 2.64
    Marker Score: 2,615
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.62
    Marker Score: 23,019
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.62
    Marker Score: 2,796
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.62
    Marker Score: 26,508
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 2.61
    Marker Score: 2,517
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.6
    Marker Score: 1,569
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.6
    Marker Score: 1,299
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 2.59
    Marker Score: 898
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.58
    Marker Score: 2,975
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.58
    Marker Score: 4,501
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.58
    Marker Score: 10,716
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.58
    Marker Score: 1,045
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.56
    Marker Score: 2,783
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 2.55
    Marker Score: 890
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.54
    Marker Score: 4,986
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 2.53
    Marker Score: 785
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 2.53
    Marker Score: 896
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 2.53
    Marker Score: 883
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 2.53
    Marker Score: 1,301
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.53
    Marker Score: 1,663
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.53
    Marker Score: 2,364
  • Cell Name: pericyte (CL0000669)
    Fold Change: 2.52
    Marker Score: 1,474
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 2.52
    Marker Score: 2,976
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 2.52
    Marker Score: 5,035

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SEPT7 exhibits several key characteristics that define its function and regulation: 1. **GTP-binding properties**: SEPT7 belongs to the septin family, which is characterized by its ability to bind GTP (guanosine triphosphate). This interaction is essential for its function in regulating cellular processes. 2. **Cytoskeletal organization**: SEPT7 interacts with various cytoskeletal proteins, including microtubules and actin filaments, to maintain cytoskeletal organization and dynamics. 3. **Cell cycle regulation**: SEPT7 is involved in regulating the cell cycle, particularly in the G2/M phase, where it helps to ensure proper chromosome segregation and cytokinesis. 4. **Signal transduction**: SEPT7 interacts with various signaling molecules, including MAPK kinases, to regulate signal transduction pathways involved in cell proliferation, differentiation, and migration. **Pathways and Functions** SEPT7 is involved in various cellular processes, including: 1. **Cytoskeleton-dependent cytokinesis**: SEPT7 regulates the formation of the cleavage furrow, a structure critical for cytokinesis, the process by which a cell divides into two daughter cells. 2. **Cell differentiation**: SEPT7 is involved in regulating cell differentiation, particularly in the development of immune cells, epithelial cells, and muscle cells. 3. **Signal transduction**: SEPT7 interacts with various signaling molecules to regulate signal transduction pathways involved in cell proliferation, differentiation, and migration. 4. **Embryonic cell shape regulation**: SEPT7 helps to regulate embryonic cell shape and morphogenesis, particularly in the development of the nervous system and immune system. **Clinical Significance** SEPT7 has been implicated in various diseases and disorders, including: 1. **Immune-related disorders**: SEPT7 expression is altered in immune cells, particularly in conditions involving immune cell dysfunction, such as autoimmune diseases and cancer. 2. **Cancer**: SEPT7 is overexpressed in various types of cancer, including breast, lung, and colon cancer, where it may contribute to tumor progression and metastasis. 3. **Neurological disorders**: SEPT7 expression is altered in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may contribute to neuronal dysfunction and degeneration. In conclusion, SEPT7 is a multifunctional protein that plays critical roles in various cellular processes, including cell division, cytoskeleton organization, and signal transduction. Its expression is altered in various diseases and disorders, highlighting the importance of SEPT7 in maintaining cellular homeostasis and promoting tissue health. Further research is needed to fully elucidate the functions and clinical significance of SEPT7.

Genular Protein ID: 3018259232

Symbol: SEPT7_HUMAN

Name: Septin-7

UniProtKB Accession Codes:

Q16181 Q52M76 Q6NX50

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 6 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 EMDB 1 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 27 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 7 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SASBDB 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8037772

Title: Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae.

PubMed ID: 8037772

DOI: 10.1006/bbrc.1994.1896

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15485874

Title: Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.

PubMed ID: 15485874

DOI: 10.1074/jbc.m406153200

PubMed ID: 15915442

Title: Expression profiling the human septin gene family.

PubMed ID: 15915442

DOI: 10.1002/path.1789

PubMed ID: 16093351

Title: Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4.

PubMed ID: 16093351

DOI: 10.1091/mbc.e05-03-0267

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16914550

Title: Structural analysis of septin 2, 6, and 7 complexes.

PubMed ID: 16914550

DOI: 10.1074/jbc.m605179200

PubMed ID: 17803907

Title: Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

PubMed ID: 17803907

DOI: 10.1016/j.cell.2007.06.053

PubMed ID: 18460473

Title: Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization.

PubMed ID: 18460473

DOI: 10.1074/jbc.m710591200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19145258

Title: Septins regulate bacterial entry into host cells.

PubMed ID: 19145258

DOI: 10.1371/journal.pone.0004196

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25588830

Title: SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octomeric complexes with other SEPT proteins.

PubMed ID: 25588830

DOI: 10.1242/jcs.158998

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 17637674

Title: Structural insight into filament formation by mammalian septins.

PubMed ID: 17637674

DOI: 10.1038/nature06052

Sequence Information:

  • Length: 437
  • Mass: 50680
  • Checksum: 946A08C54B7124FF
  • Sequence:
    • MSVSARSAAA EERSVNSSTM VAQQKNLEGY VGFANLPNQV YRKSVKRGFE FTLMVVGESG 
LGKSTLINSL FLTDLYSPEY PGPSHRIKKT VQVEQSKVLI KEGGVQLLLT IVDTPGFGDA 
VDNSNCWQPV IDYIDSKFED YLNAESRVNR RQMPDNRVQC CLYFIAPSGH GLKPLDIEFM 
KRLHEKVNII PLIAKADTLT PEECQQFKKQ IMKEIQEHKI KIYEFPETDD EEENKLVKKI 
KDRLPLAVVG SNTIIEVNGK RVRGRQYPWG VAEVENGEHC DFTILRNMLI RTHMQDLKDV 
TNNVHYENYR SRKLAAVTYN GVDNNKNKGQ LTKSPLAQME EERREHVAKM KKMEMEMEQV 
FEMKVKEKVQ KLKDSEAELQ RRHEQMKKNL EAQHKELEEK RRQFEDEKAN WEAQQRILEQ 
QNSSRTLEKN KKKGKIF

Genular Protein ID: 1636037073

Symbol: A8K3D0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K3D0

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 8 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1 iPTMnet 1

Sequence Information:

  • Length: 436
  • Mass: 50509
  • Checksum: 8030F08F60C173DB
  • Sequence:
    • MSVSARSAAA EERSVNSSTM AQQKNLEGYV GFANLPNQVY RKSVKRGFEF TLMVVGESGL 
GKSTLINSLF LTDLYSPEYP GPSHRIKKTV QVEQSKVLIK EGGVQLLLTI VDTPGFGDAV 
DNSNCWQPVI DYIDSKFEDY LNAESRVNRR QMPDNRVQCC LYFIAPSGHG LKPLDIEFMK 
RLHEKVNIIP LIAKADTLTP EECQQFKKQI MKEIQEHKIK IYEFPETDDE EENKLVKKIK 
DRLPLAVVGS NTIIEVNGKR VRGRQYPWGV AEVENGEHCD FTILRNMLIR THMQDLKDVT 
NNVHYENYRS RKLAAVTYNG VDNNKNKGQL TKSPLAQMEE ERREHVAKMK KMEMGMEQVF 
EMKVKEKVQK LKDSEAELQR RHEQMKKNLE AQHKELEEKR RQFEDEKANW EAQQRILEQQ 
NSSRTLEKNK KKGKIF

Genular Protein ID: 3191608957

Symbol: B4DNE4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DNE4

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 8 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 4 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 382
  • Mass: 44644
  • Checksum: 1F183832F7A22DA9
  • Sequence:
    • MGESGLGKST LINSLFLTDL YSPEYPGPSH RIKKTVQVEQ SKVLIKEGGV QLLLTIVDTP 
GFGDAVDNSN CWQPVIDYID SKFEDYLNAE SRVNRRQMPD NRVQCCLYFI APSGHGLKPL 
DIEFMKRLHE KVNIIPLIAK ADTLTPEECQ QFKKQIMKEI QEHKIKIYEF PETDDEEENK 
LVKKIKDRLP LAVVGSNTII EVNGKRVRGR QYPWGVAEVE NGEHCDFTIL RNMLIRTHMQ 
DLKDVTNNVH YENYRSRKLA AVTYNGVDNN KNKGQLTKSP LAQMEEERRE HVAKMKKMEM 
EMEQVFEMKV KEKVQKLKDS EAELQRRHEQ MKKNLEAQHK ELEEKRRQFE DEKANWEAQQ 
RILEQQNSSR TLEKNKKKGK IF

Genular Protein ID: 1993019917

Symbol: G3V1Q4_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3V1Q4

Database IDs:

ARBA 13 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 4 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 401
  • Mass: 46566
  • Checksum: 3B79676A684FE210
  • Sequence:
    • MSVSARSAAA EERSVNSSTM GESGLGKSTL INSLFLTDLY SPEYPGPSHR IKKTVQVEQS 
KVLIKEGGVQ LLLTIVDTPG FGDAVDNSNC WQPVIDYIDS KFEDYLNAES RVNRRQMPDN 
RVQCCLYFIA PSGHGLKPLD IEFMKRLHEK VNIIPLIAKA DTLTPEECQQ FKKQIMKEIQ 
EHKIKIYEFP ETDDEEENKL VKKIKDRLPL AVVGSNTIIE VNGKRVRGRQ YPWGVAEVEN 
GEHCDFTILR NMLIRTHMQD LKDVTNNVHY ENYRSRKLAA VTYNGVDNNK NKGQLTKSPL 
AQMEEERREH VAKMKKMEME MEQVFEMKVK EKVQKLKDSE AELQRRHEQM KKNLEAQHKE 
LEEKRRQFED EKANWEAQQR ILEQQNSSRT LEKNKKKGKI F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.