Details for: TELO2

Gene ID: 9894

Symbol: TELO2

Ensembl ID: ENSG00000100726

Description: telomere maintenance 2

Associated with

Other Information

Genular Protein ID: 1686873157

Symbol: TELO2_HUMAN

Name: Telomere length regulation protein TEL2 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11157797

Title: Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.

PubMed ID: 11157797

DOI: 10.1093/hmg/10.4.339

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12670948

Title: Human CLK2 links cell cycle progression, apoptosis, and telomere length regulation.

PubMed ID: 12670948

DOI: 10.1074/jbc.m300286200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20810650

Title: A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

PubMed ID: 20810650

DOI: 10.1101/gad.1934210

PubMed ID: 20801936

Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.

PubMed ID: 20801936

DOI: 10.1101/gad.1956410

PubMed ID: 20427287

Title: Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

PubMed ID: 20427287

DOI: 10.1074/jbc.m110.121699

PubMed ID: 20864032

Title: CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.

PubMed ID: 20864032

DOI: 10.1016/j.molcel.2010.08.037

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22797300

Title: PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.

PubMed ID: 22797300

DOI: 10.1172/jci62374

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23263282

Title: SCF(Fbxo9) and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.

PubMed ID: 23263282

DOI: 10.1038/ncb2651

PubMed ID: 27132593

Title: A syndromic intellectual disability disorder caused by variants in TELO2, a gene encoding a component of the TTT complex.

PubMed ID: 27132593

DOI: 10.1016/j.ajhg.2016.03.014

PubMed ID: 24656813

Title: Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex.

PubMed ID: 24656813

DOI: 10.1016/j.celrep.2014.03.013

Sequence Information:

  • Length: 837
  • Mass: 91747
  • Checksum: 76CB619C73C1F1A7
  • Sequence:
  • MEPAPSEVRL AVREAIHALS SSEDGGHIFC TLESLKRYLG EMEPPALPRE KEEFASAHFS 
    PVLRCLASRL SPAWLELLPH GRLEELWASF FLEGPADQAF LVLMETIEGA AGPSFRLMKM 
    ARLLARFLRE GRLAVLMEAQ CRQQTQPGFI LLRETLLGKV VALPDHLGNR LQQENLAEFF 
    PQNYFRLLGE EVVRVLQAVV DSLQGGLDSS VSFVSQVLGK ACVHGRQQEI LGVLVPRLAA 
    LTQGSYLHQR VCWRLVEQVP DRAMEAVLTG LVEAALGPEV LSRLLGNLVV KNKKAQFVMT 
    QKLLFLQSRL TTPMLQSLLG HLAMDSQRRP LLLQVLKELL ETWGSSSAIR HTPLPQQRHV 
    SKAVLICLAQ LGEPELRDSR DELLASMMAG VKCRLDSSLP PVRRLGMIVA EVVSARIHPE 
    GPPLKFQYEE DELSLELLAL ASPQPAGDGA SEAGTSLVPA TAEPPAETPA EIVDGGVPQA 
    QLAGSDSDLD SDDEFVPYDM SGDRELKSSK APAYVRDCVE ALTTSEDIER WEAALRALEG 
    LVYRSPTATR EVSVELAKVL LHLEEKTCVV GFAGLRQRAL VAVTVTDPAP VADYLTSQFY 
    ALNYSLRQRM DILDVLTLAA QELSRPGCLG RTPQPGSPSP NTPCLPEAAV SQPGSAVASD 
    WRVVVEERIR SKTQRLSKGG PRQGPAGSPS RFNSVAGHFF FPLLQRFDRP LVTFDLLGED 
    QLVLGRLAHT LGALMCLAVN TTVAVAMGKA LLEFVWALRF HIDAYVRQGL LSAVSSVLLS 
    LPAARLLEDL MDELLEARSW LADVAEKDPD EDCRTLALRA LLLLQRLKNR LLPPASP

Genular Protein ID: 2486338529

Symbol: B4DXS2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 431
  • Mass: 47808
  • Checksum: 8E3DFA2DADFB949C
  • Sequence:
  • MEPAPSEVRL AVREAIHALS SSEDGGHIFC TLESLKRYLG EMEPPTLPRE KEEFASAHFS 
    PVLRCLASRL SPAWLELLPH GRLEELWASF FLEGPADQAF LVLMETIEGA AGPSFRLMKM 
    ARLLARFLRE GRLAVLMEAQ CRQQTQPGFI LLRETLLGKV VALPDHLGNR LQQENLAEFF 
    PQNYFRLLGE EVVRVLQAVV DSLQGGLDSS VSFVSQVLGK ACVHGRQQEI LGVLVPRLAA 
    LTQGSYLHQR VCWRLVEQVP DRAMEAVLTG LVEAALGPEV LSRLLGNLVV KNKKAQFVMT 
    QKLLFLQSRL TTPMLQSLLG HLAMDSQRRP LLLQVLKELL ETWGSSSAIR HTPLPQQRHV 
    SKAVLICLAQ LGEPELRDSR DELLASMMAG VKCRLDSSLP PVRRLGMIVA DSTPWPATSS 
    SPSFSALTGL W

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.