Details for: CDC25A

Gene ID: 993

Symbol: CDC25A

Ensembl ID: ENSG00000164045

Description: cell division cycle 25A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 19.5442
    Cell Significance Index: -3.0400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 16.9924
    Cell Significance Index: -4.3100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 10.6829
    Cell Significance Index: -4.3400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 4.5457
    Cell Significance Index: -4.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 3.5849
    Cell Significance Index: -4.4200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 2.3497
    Cell Significance Index: 38.7200
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.1118
    Cell Significance Index: 8.4000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6620
    Cell Significance Index: 65.4900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.6385
    Cell Significance Index: 15.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5969
    Cell Significance Index: 16.0000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.5185
    Cell Significance Index: 12.9300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4702
    Cell Significance Index: 28.2300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.4006
    Cell Significance Index: 8.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3513
    Cell Significance Index: 38.2200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3028
    Cell Significance Index: 49.2400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2887
    Cell Significance Index: 4.1400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.2631
    Cell Significance Index: 2.8600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1945
    Cell Significance Index: 6.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1812
    Cell Significance Index: 35.9600
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.1658
    Cell Significance Index: 1.1000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1599
    Cell Significance Index: 18.6300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1555
    Cell Significance Index: 4.4800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1389
    Cell Significance Index: 3.0100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1234
    Cell Significance Index: 3.3000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1212
    Cell Significance Index: 6.8000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1103
    Cell Significance Index: 99.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1070
    Cell Significance Index: 4.8500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1049
    Cell Significance Index: 19.9700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0961
    Cell Significance Index: 11.3300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0893
    Cell Significance Index: 6.1800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0876
    Cell Significance Index: 2.5800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0743
    Cell Significance Index: 4.6900
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0720
    Cell Significance Index: 1.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0710
    Cell Significance Index: 3.6900
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.0708
    Cell Significance Index: 0.4700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0647
    Cell Significance Index: 44.7300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0583
    Cell Significance Index: 1.6300
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0526
    Cell Significance Index: 0.7300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0366
    Cell Significance Index: 0.7800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0328
    Cell Significance Index: 17.9100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0301
    Cell Significance Index: 0.6300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0233
    Cell Significance Index: 0.3900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0216
    Cell Significance Index: 0.7600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0215
    Cell Significance Index: 0.6900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0184
    Cell Significance Index: 0.3100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0178
    Cell Significance Index: 7.8800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0176
    Cell Significance Index: 0.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0115
    Cell Significance Index: 1.6700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0048
    Cell Significance Index: 0.0700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0027
    Cell Significance Index: 0.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0014
    Cell Significance Index: 0.5100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0002
    Cell Significance Index: 0.4300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0002
    Cell Significance Index: 0.0100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0011
    Cell Significance Index: -0.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0023
    Cell Significance Index: -4.2800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0023
    Cell Significance Index: -3.4900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0027
    Cell Significance Index: -3.6400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0029
    Cell Significance Index: -0.0800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0037
    Cell Significance Index: -0.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0054
    Cell Significance Index: -3.4600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0058
    Cell Significance Index: -4.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0062
    Cell Significance Index: -4.6800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0065
    Cell Significance Index: -1.3000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0073
    Cell Significance Index: -2.0900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0075
    Cell Significance Index: -5.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0092
    Cell Significance Index: -1.1300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0095
    Cell Significance Index: -5.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0098
    Cell Significance Index: -5.5000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0109
    Cell Significance Index: -4.9400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0110
    Cell Significance Index: -1.5100
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0185
    Cell Significance Index: -0.1100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0186
    Cell Significance Index: -3.1800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0191
    Cell Significance Index: -1.3500
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0258
    Cell Significance Index: -0.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0293
    Cell Significance Index: -6.1700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0305
    Cell Significance Index: -3.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0327
    Cell Significance Index: -3.3500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0378
    Cell Significance Index: -2.4400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0392
    Cell Significance Index: -4.4900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0422
    Cell Significance Index: -2.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0439
    Cell Significance Index: -4.5700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0522
    Cell Significance Index: -4.0100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0572
    Cell Significance Index: -0.6500
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.0580
    Cell Significance Index: -0.3700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0589
    Cell Significance Index: -0.6100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0590
    Cell Significance Index: -4.6700
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0592
    Cell Significance Index: -0.7500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0603
    Cell Significance Index: -2.4700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0624
    Cell Significance Index: -1.6400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0657
    Cell Significance Index: -0.9900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0680
    Cell Significance Index: -5.0700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0701
    Cell Significance Index: -0.4800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0721
    Cell Significance Index: -4.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0780
    Cell Significance Index: -5.2500
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0784
    Cell Significance Index: -0.9900
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.0805
    Cell Significance Index: -1.0000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0805
    Cell Significance Index: -2.0700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0812
    Cell Significance Index: -4.1000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0864
    Cell Significance Index: -4.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0956
    Cell Significance Index: -5.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Phosphatase activity:** CDC25A is a phosphatase enzyme that dephosphorylates and activates cyclin-dependent kinases (CDKs), particularly CDK1, which drives the G2/M transition. 2. **ATR activation:** CDC25A is involved in the activation of the ATR kinase in response to replication stress, leading to the activation of cell cycle checkpoints and DNA repair mechanisms. 3. **Regulation of cell cycle checkpoints:** CDC25A is required for the proper functioning of cell cycle checkpoints, including the G1/S and G2/M checkpoints, to prevent aberrant cell proliferation. 4. **Neurodegenerative diseases:** CDC25A has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease, where its dysregulation triggers multiple neurodegenerative pathways. **Pathways and Functions:** 1. **Cell cycle regulation:** CDC25A is involved in the regulation of the cell cycle, particularly during the G2/M transition, where it activates CDK1 and drives the cell cycle forward. 2. **DNA damage response:** CDC25A is required for the activation of the ATR kinase in response to DNA damage, leading to the activation of cell cycle checkpoints and DNA repair mechanisms. 3. **Apoptosis:** CDC25A is involved in the regulation of apoptosis, particularly in the context of DNA damage, where its dysregulation can lead to defective intrinsic pathways for apoptosis. 4. **Neurodegenerative diseases:** CDC25A has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease, where its dysregulation triggers multiple neurodegenerative pathways. **Clinical Significance:** 1. **Cancer:** CDC25A is overexpressed in various types of cancer, including breast, lung, and colon cancer, where its dysregulation contributes to tumorigenesis and cancer progression. 2. **Neurodegenerative diseases:** CDC25A has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, where its dysregulation contributes to disease progression. 3. **Metabolic disorders:** CDC25A has been implicated in the regulation of metabolic disorders, including diabetes and obesity, where its dysregulation contributes to metabolic dysfunction. 4. **Immunological disorders:** CDC25A has been implicated in the regulation of immunological disorders, including autoimmune diseases and immunodeficiency disorders, where its dysregulation contributes to immune dysfunction. In conclusion, CDC25A is a critical phosphatase enzyme that plays a pivotal role in regulating the cell cycle, particularly during the G2/M transition. Its dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, metabolic disorders, and immunological disorders. Further research is needed to fully understand the role of CDC25A in human disease and to develop therapeutic strategies to target this enzyme in the treatment of these diseases.

Genular Protein ID: 566855348

Symbol: MPIP1_HUMAN

Name: M-phase inducer phosphatase 1

UniProtKB Accession Codes:

P30304 Q8IZH5 Q96IL3 Q9H2F2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DEPOD 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 1 ELM 1 EMBL 6 EMDB 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 9 RefSeq 3 Rhea 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1836978

Title: Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins.

PubMed ID: 1836978

DOI: 10.1016/0092-8674(91)90294-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11139144

Title: Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.

PubMed ID: 11139144

DOI: 10.1078/0171-9335-00115

PubMed ID: 11298456

Title: The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.

PubMed ID: 11298456

DOI: 10.1038/35071124

PubMed ID: 12234927

Title: Dual mode of degradation of Cdc25 A phosphatase.

PubMed ID: 12234927

DOI: 10.1093/emboj/cdf491

PubMed ID: 12399544

Title: Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

PubMed ID: 12399544

DOI: 10.1073/pnas.182557299

PubMed ID: 12676583

Title: Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

PubMed ID: 12676583

DOI: 10.1016/s1535-6108(03)00048-5

PubMed ID: 14681206

Title: SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.

PubMed ID: 14681206

DOI: 10.1101/gad.1157503

PubMed ID: 12676925

Title: Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.

PubMed ID: 12676925

DOI: 10.1074/jbc.m300229200

PubMed ID: 12759351

Title: Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint.

PubMed ID: 12759351

DOI: 10.1074/jbc.m302704200

PubMed ID: 14559997

Title: Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding.

PubMed ID: 14559997

DOI: 10.1128/mcb.23.21.7488-7497.2003

PubMed ID: 16356754

Title: The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.

PubMed ID: 16356754

DOI: 10.1016/j.biocel.2005.10.010

PubMed ID: 19734889

Title: NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint.

PubMed ID: 19734889

DOI: 10.1038/ncb1969

PubMed ID: 20090422

Title: NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.

PubMed ID: 20090422

DOI: 10.4161/cc.9.3.10513

PubMed ID: 20360007

Title: Cdc25 phosphatases are required for timely assembly of CDK1-cyclin B at the G2/M transition.

PubMed ID: 20360007

DOI: 10.1074/jbc.m109.096552

PubMed ID: 20228808

Title: Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

PubMed ID: 20228808

DOI: 10.1038/ncb2041

PubMed ID: 21376736

Title: Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors.

PubMed ID: 21376736

DOI: 10.1016/j.mrfmmm.2011.02.006

PubMed ID: 22843495

Title: Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells.

PubMed ID: 22843495

DOI: 10.1093/hmg/dds303

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 9604936

Title: Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A.

PubMed ID: 9604936

DOI: 10.1016/s0092-8674(00)81190-3

Sequence Information:

  • Length: 524
  • Mass: 59087
  • Checksum: B2F6B792D4E6122B
  • Sequence:
    • MELGPEPPHR RRLLFACSPP PASQPVVKAL FGASAAGGLS PVTNLTVTMD QLQGLGSDYE 
QPLEVKNNSN LQRMGSSEST DSGFCLDSPG PLDSKENLEN PMRRIHSLPQ KLLGCSPALK 
RSHSDSLDHD IFQLIDPDEN KENEAFEFKK PVRPVSRGCL HSHGLQEGKD LFTQRQNSAP 
ARMLSSNERD SSEPGNFIPL FTPQSPVTAT LSDEDDGFVD LLDGENLKNE EETPSCMASL 
WTAPLVMRTT NLDNRCKLFD SPSLCSSSTR SVLKRPERSQ EESPPGSTKR RKSMSGASPK 
ESTNPEKAHE TLHQSLSLAS SPKGTIENIL DNDPRDLIGD FSKGYLFHTV AGKHQDLKYI 
SPEIMASVLN GKFANLIKEF VIIDCRYPYE YEGGHIKGAV NLHMEEEVED FLLKKPIVPT 
DGKRVIVVFH CEFSSERGPR MCRYVRERDR LGNEYPKLHY PELYVLKGGY KEFFMKCQSY 
CEPPSYRPMH HEDFKEDLKK FRTKSRTWAG EKSKREMYSR LKKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.