Details for: HELZ

Gene ID: 9931

Symbol: HELZ

Ensembl ID: ENSG00000198265

Description: helicase with zinc finger

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.66
    Marker Score: 1,548
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.61
    Marker Score: 1,452
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.52
    Marker Score: 5,541
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.37
    Marker Score: 42,100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.27
    Marker Score: 3,051
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.21
    Marker Score: 9,234
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.21
    Marker Score: 47,077
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.18
    Marker Score: 32,665
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.18
    Marker Score: 43,294
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.16
    Marker Score: 82,161
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.16
    Marker Score: 2,612
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.14
    Marker Score: 2,464
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.14
    Marker Score: 16,401
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.13
    Marker Score: 9,874
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.08
    Marker Score: 8,615
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.06
    Marker Score: 6,748
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.06
    Marker Score: 601
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.06
    Marker Score: 75,842
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.05
    Marker Score: 2,266
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.02
    Marker Score: 1,006
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.98
    Marker Score: 7,674
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.96
    Marker Score: 2,118
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.94
    Marker Score: 1,082
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.92
    Marker Score: 3,696
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.92
    Marker Score: 1,009
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.9
    Marker Score: 7,749
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.87
    Marker Score: 1,442
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.87
    Marker Score: 114,792
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.86
    Marker Score: 781
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.85
    Marker Score: 6,576
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.85
    Marker Score: 41,307
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.84
    Marker Score: 795
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.83
    Marker Score: 1,957
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.82
    Marker Score: 17,124
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.79
    Marker Score: 7,446
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.78
    Marker Score: 1,039
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.77
    Marker Score: 1,059
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.76
    Marker Score: 16,729
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.74
    Marker Score: 28,008
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.73
    Marker Score: 14,882
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.72
    Marker Score: 1,192
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.7
    Marker Score: 636
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.65
    Marker Score: 835
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.64
    Marker Score: 16,968
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.62
    Marker Score: 1,434
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.61
    Marker Score: 4,033
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.61
    Marker Score: 782
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.61
    Marker Score: 1,534
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.61
    Marker Score: 508
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.6
    Marker Score: 580
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.6
    Marker Score: 1,976
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.57
    Marker Score: 1,891
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.53
    Marker Score: 1,325
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.53
    Marker Score: 558
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.52
    Marker Score: 1,317
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.51
    Marker Score: 9,690
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.51
    Marker Score: 1,236
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.49
    Marker Score: 2,107
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.48
    Marker Score: 1,561
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.48
    Marker Score: 404
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.47
    Marker Score: 2,263
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.47
    Marker Score: 7,877
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.46
    Marker Score: 1,825
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.46
    Marker Score: 531
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.46
    Marker Score: 722
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.46
    Marker Score: 420
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.46
    Marker Score: 538
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.43
    Marker Score: 1,617
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.43
    Marker Score: 363
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.42
    Marker Score: 48,045
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.41
    Marker Score: 6,094
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.41
    Marker Score: 1,295
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.41
    Marker Score: 1,491
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.38
    Marker Score: 560
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.37
    Marker Score: 1,033
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.37
    Marker Score: 708
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.36
    Marker Score: 764
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.36
    Marker Score: 463
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.35
    Marker Score: 75,228
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.33
    Marker Score: 3,183
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.31
    Marker Score: 314
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.31
    Marker Score: 494
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.31
    Marker Score: 4,645
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.31
    Marker Score: 415
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.3
    Marker Score: 3,248
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.27
    Marker Score: 833
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.26
    Marker Score: 890
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.26
    Marker Score: 919
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.26
    Marker Score: 1,260
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.26
    Marker Score: 2,964
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.25
    Marker Score: 3,937
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.24
    Marker Score: 1,757
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.24
    Marker Score: 846
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.24
    Marker Score: 499
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 1.23
    Marker Score: 361
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 1.23
    Marker Score: 929
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.22
    Marker Score: 296
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.22
    Marker Score: 1,234
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.21
    Marker Score: 421
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.21
    Marker Score: 421

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Helicase Activity:** The HELZ protein possesses helicase activity, which is essential for DNA unwinding and replication. This activity is mediated by a zinc finger domain, a structural motif that enables the protein to bind to DNA and facilitate the unwinding process. 2. **Zinc Finger Domain:** The zinc finger domain is a conserved structural motif that is characteristic of many helicases, including the HELZ protein. This domain plays a critical role in mediating protein-DNA interactions and facilitating helicase activity. 3. **Cellular Expression:** The HELZ gene is predominantly expressed in various cell types, including corneal endothelial cells, alveolar type 2 fibroblasts, and cortical cells of the adrenal gland. This expression pattern suggests that the HELZ protein may play a role in maintaining tissue homeostasis and regulating cellular processes. 4. **Protein-Protein Interactions:** The HELZ protein interacts with various proteins, including B7ZLW2 and A0A2P0H7U5, which may contribute to its regulatory functions and cellular localization. **Pathways and Functions:** 1. **DNA Replication and Repair:** The HELZ protein's helicase activity is essential for DNA replication and repair. By unwinding DNA, the HELZ protein enables the replication machinery to access and synthesize new DNA strands. 2. **Transcriptional Regulation:** The HELZ protein may also play a role in transcriptional regulation, particularly in the context of gene silencing mediated by small interfering RNAs (siRNAs). 3. **Cellular Signaling:** The HELZ protein's protein-protein interactions and cellular localization may contribute to its involvement in cellular signaling pathways, including those regulating cell proliferation, differentiation, and survival. **Clinical Significance:** 1. **Immunological Disorders:** The HELZ gene's involvement in DNA replication and repair may contribute to the development of immunological disorders, such as autoimmune diseases and cancer. 2. **Tissue Homeostasis:** The HELZ protein's expression in corneal endothelial cells and other tissue-specific cells may suggest its role in maintaining tissue homeostasis and regulating cellular processes. 3. **Cancer Research:** The HELZ protein's helicase activity and protein-protein interactions may provide insights into the development and progression of cancer, highlighting potential therapeutic targets for cancer treatment. In conclusion, the HELZ gene is a novel gene that encodes a protein with helicase activity and zinc finger domain. Its expression in various cell types and involvement in DNA replication and repair, transcriptional regulation, and cellular signaling pathways make it a significant player in the context of immunological disorders and tissue homeostasis. Further research is needed to elucidate the HELZ gene's clinical significance and potential therapeutic applications.

Genular Protein ID: 3048608340

Symbol: HELZ_HUMAN

Name: Probable helicase with zinc finger domain

UniProtKB Accession Codes:

P42694 I6L9H4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 10 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7584044

Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7584044

DOI: 10.1093/dnares/1.5.223

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10471385

Title: Identification of a differentially expressed RNA helicase by gene trapping.

PubMed ID: 10471385

DOI: 10.1006/bbrc.1999.1208

PubMed ID: 12691822

Title: Down-regulation in human cancers of DRHC, a novel helicase-like gene from 17q25.1 that inhibits cell growth.

PubMed ID: 12691822

DOI: 10.1016/s0304383502006882

PubMed ID: 15235609

Title: SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.

PubMed ID: 15235609

DOI: 10.1038/ncb1151

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

  • Length: 1942
  • Mass: 218970
  • Checksum: B2EA41681C1A327D
  • Sequence:
    • MEDRRAEKSC EQACESLKRQ DYEMALKHCT EALLSLGQYS MADFTGPCPL EIERIKIESL 
LYRIASFLQL KNYVQADEDC RHVLGEGLAK GEDAFRAVLC CMQLKGKLQP VSTILAKSLT 
GESLNGMVTK DLTRLKTLLS ETETATSNAL SGYHVEDLDE GSCNGWHFRP PPRGITSSEE 
YTLCKRFLEQ GICRYGAQCT SAHSQEELAE WQKRYASRLI KLKQQNENKQ LSGSYMETLI 
EKWMNSLSPE KVLSECIEGV KVEHNPDLSV TVSTKKSHQT WTFALTCKPA RMLYRVALLY 
DAHRPHFSII AISAGDSTTQ VSQEVPENCQ EWIGGKMAQN GLDHYVYKVG IAFNTEIFGT 
FRQTIVFDFG LEPVLMQRVM IDAASTEDLE YLMHAKQQLV TTAKRWDSSS KTIIDFEPNE 
TTDLEKSLLI RYQIPLSADQ LFTQSVLDKS LTKSNYQSRL HDLLYIEEIA QYKEISKFNL 
KVQLQILASF MLTGVSGGAK YAQNGQLFGR FKLTETLSED TLAGRLVMTK VNAVYLLPVP 
KQKLVQTQGT KEKVYEATIE EKTKEYIFLR LSRECCEELN LRPDCDTQVE LQFQLNRLPL 
CEMHYALDRI KDNGVLFPDI SMTPTIPWSP NRQWDEQLDP RLNAKQKEAV LAITTPLAIQ 
LPPVLIIGPY GTGKTFTLAQ AVKHILQQQE TRILICTHSN SAADLYIKDY LHPYVEAGNP 
QARPLRVYFR NRWVKTVHPV VHQYCLISSA HSTFQMPQKE DILKHRVVVV TLNTSQYLCQ 
LDLEPGFFTH ILLDEAAQAM ECETIMPLAL ATQNTRIVLA GDHMQLSPFV YSEFARERNL 
HVSLLDRLYE HYPAEFPCRI LLCENYRSHE AIINYTSELF YEGKLMASGK QPAHKDFYPL 
TFFTARGEDV QEKNSTAFYN NAEVFEVVER VEELRRKWPV AWGKLDDGSI GVVTPYADQV 
FRIRAELRKK RLSDVNVERV LNVQGKQFRV LFLSTVRTRH TCKHKQTPIK KKEQLLEDST 
EDLDYGFLSN YKLLNTAITR AQSLVAVVGD PIALCSIGRC RKFWERFIAL CHENSSLHGI 
TFEQIKAQLE ALELKKTYVL NPLAPEFIPR ALRLQHSGST NKQQQSPPKG KSLHHTQNDH 
FQNDGIVQPN PSVLIGNPIR AYTPPPPLGP HPNLGKSPSP VQRIDPHTGT SILYVPAVYG 
GNVVMSVPLP VPWTGYQGRF AVDPRIITHQ AAMAYNMNLL QTHGRGSPIP YGLGHHPPVT 
IGQPQNQHQE KDQHEQNRNG KSDTNNSGPE INKIRTPEKK PTEPKQVDLE SNPQNRSPES 
RPSVVYPSTK FPRKDNLNPR HINLPLPAPH AQYAIPNRHF HPLPQLPRPP FPIPQQHTLL 
NQQQNNLPEQ PNQIPPQPNQ VVQQQSQLNQ QPQQPPPQLS PAYQAGPNNA FFNSAVAHRP 
QSPPAEAVIP EQQPPPMLQE GHSPLRAIAQ PGPILPSHLN SFIDENPSGL PIGEALDRIH 
GSVALETLRQ QQARFQQWSE HHAFLSQGSA PYPHHHHPHL QHLPQPPLGL HQPPVRADWK 
LTSSAEDEVE TTYSRFQDLI RELSHRDQSE TRELAEMPPP QSRLLQYRQV QSRSPPAVPS 
PPSSTDHSSH FSNFNDNSRD IEVASNPAFP QRLPPQIFNS PFSLPSEHLA PPPLKYLAPD 
GAWTFANLQQ NHLMGPGFPY GLPPLPHRPP QNPFVQIQNH QHAIGQEPFH PLSSRTVSSS 
SLPSLEEYEP RGPGRPLYQR RISSSSVQPC SEEVSTPQDS LAQCKELQDH SNQSSFNFSS 
PESWVNTTSS TPYQNIPCNG SSRTAQPREL IAPPKTVKPP EDQLKSENLE VSSSFNYSVL 
QHLGQFPPLM PNKQIAESAN SSSPQSSAGG KPAMSYASAL RAPPKPRPPP EQAKKSSDPL 
SLFQELSLGS SSGSNGFYSY FK

Genular Protein ID: 2624958754

Symbol: B7ZLW2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZLW2

Database IDs:

ARBA 4 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 8 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SMART 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1943
  • Mass: 219117
  • Checksum: 6BE4254EBE3B3AB8
  • Sequence:
    • MEDRRAEKSC EQACESLKRQ DYEMALKHCT EALLSLGQYS MADFTGPCPL EIERIKIESL 
LYRIASFLQL KNYMQADEDC RHVLGEGLAK GEDAFRAVLC CMQLKGKLQP VSTILAKSLT 
GESLNGMVTK DLTRLKTLLS ETETATSNAL SGYHVEDLDE GSCNGWHFRP PPRGITSSEE 
YTLCKRFLEQ GICRYGAQCT SAHSQEELAE WQKRYASRLI KLKQQNENKQ LSGSYMETLI 
EKWMNSLSPE KVLSECIEGV KVEHNPDLSV TVSTKKSHQT WTFALTCKPA RMLYRVALLY 
DAHRPHFSII AISAGDSTTQ VSQEVPENCQ EWIGGKMAQN GLDHYVYKVG IAFNTEIFGT 
FRQTIVFDFG LEPVLMQRVM IDAASTEDLE YLMHAKQQLV TTAKRWDSSS KTIIDFEPNE 
TTDLEKSLLI RYQIPLSADQ LFTQSVLDKS LTKSNYQSRL HDLLYIEEIA QYKEISKFNL 
KVQLQILASF MLTGVSGGAK YAQNGQLFGR FKLTETLSED TLAGRLVMTK VNAVYLLPVP 
KQKLVQTQGT KEKVYEATIE EKTKEYIFLR LSRECCEELN LRPDCDTQVE LQFQLNRLPL 
CEMHYALDRI KDNGVLFPDI SMTPTIPWSP NRQWDEQLDP RLNAKQKEAV LAITTPLAIQ 
LPPVLIIGPY GTGKTFTLAQ AVKHILQQQE TSRILICTHS NSAADLYIKD YLHPYVEAGN 
PQARPLRVYF RNRWVKTVHP VVHQYCLISS AHSTFQMPQK EDILKHRVVV VTLNTSQYLC 
QLDLEPGFFT HILLDEAAQA MECETIMPLA LATQNTRIVL AGDHMQLSPF VYSEFARERN 
LHVSLLDRLY EHYPAEFPCR ILLCENYRSH EAIINYTSEL FYEGKLMASG KQPAHKDFYP 
LTFFTARGED VQEKNSTAFY NNAEVFEVVE RVEELRRKWP VAWGKLDDGS IGVVTPYADQ 
VFRIRAELRK KRLSDVNVER VLNVQGKQFR VLFLSTVRTR HTCKHKQTPI KKKEQLLEDS 
TEDLDYGFLS NYKLLNTAIT RAQSLVAVVG DPIALCSIGR CRKFWERFIA LCHENSSLHG 
ITFEQIKAQL EALELKKTYV LNPLAPEFIP RALRLQHSGS TNKQQQSPPK GKSLHHTQND 
HFQNDGIVQP NPSVLIGNPI RAYTPPPPLG PHPNLGKSPS PVQRIDPHTG TSILYVPAVY 
GGNVVMSVPL PVPWTGYQGR FAVDPRIITH QAAMAYNMNL LQTHGRGSPI PYGLGHHPPV 
TIGQPQNQHQ EKDQHEQNRN GKSDTNNSGP EINKIRTPEK KPTEPKQVDL ESNPQNRSPE 
SRPSVVYPST KFPRKDNLNP RHINLPLPAP HAQYAIPNRH FHPLPQLPRP PFPIPQQHTL 
LNQQQNNLPE QPNQIPPQPN QVVQQQSQLN QQPQQPPPQL SPAYQAGPNN AFFNSAVAHR 
PQSPPAEAVI PEQQPPPMLQ EGHSPLRAIA QPGPILPSHL NSFIDENPSG LPIGEALDRI 
HGSVALETLR QQQARFQQWS EHHAFLSQGS VPYPHHHHPH LQHLPQPPLG LHQPPVRADW 
KLTSSAEDEV ETTYSRFQDL IRELSHRDQS ETRELAEMPP PQSRLLQYRQ VQSRSPPAVP 
SPPSSTDHSS HFSNFNDNSR DIEVASNPAF PQRLPPQIFN SPFSLPSEHL APPPLKYLAP 
DGAWTFANLQ QNHLMGPGFP YGLPPLPHRP PQNPFVQIQN HQHAIGQEPF HPLSSRTVSS 
SSLPSLEEYE PRGPGRPLYQ RRISSSSVQP CSEEVSTPQD SLAQCKELQD HSNQSSFNFS 
SPESWVNTTS STPYQNIPCN GSSRTAQPRE LIAPPKTVKP PEDQLKSENL EVSSSFNYSV 
LQHLGQFPPL MPNKQIAESA NSSSPQSSAG GKPAMSYASA LRAPPKPRPP PEQAKKSSDP 
LSLFQELSLG SSSGSNGFYS YFK

Genular Protein ID: 3745743089

Symbol: A0A2P0H7U5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2P0H7U5

Database IDs:

ARBA 5 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 InterPro 8 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SMART 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1942
  • Mass: 219030
  • Checksum: 1A834FCD3B3411F9
  • Sequence:
    • MEDRRAEKSC EQACESLKRQ DYEMALKHCT EALLSLGQYS MADFTGPCPL EIERIKIESL 
LYRIASFLQL KNYMQADEDC RHVLGEGLAK GEDAFRAVLC CMQLKGKLQP VSTILAKSLT 
GESLNGMVTK DLTRLKTLLS ETETATSNAL SGYHVEDLDE GSCNGWHFRP PPRGITSSEE 
YTLCKRFLEQ GICRYGAQCT SAHSQEELAE WQKRYASRLI KLKQQNENKQ LSGSYMETLI 
EKWMNSLSPE KVLSECIEGV KVEHNPDLSV TVSTKKSHQT WTFALTCKPA RMLYRVALLY 
DAHRPHFSII AISAGDSTTQ VSQEVPENCQ EWIGGKMAQN GLDHYVYKVG IAFNTEIFGT 
FRQTIVFDFG LEPVLMQRVM IDAASTEDLE YLMHAKQQLV TTAKRWDSSS KTIIDFEPNE 
TTDLEKSLLI RYQIPLSADQ LFTQSVLDKS LTKSNYQSRL HDLLYIEEIA QYKEISKFNL 
KVQLQILASF MLTGVSGGAK YAQNGQLFGR FKLTETLSED TLAGRLVMTK VNAVYLLPVP 
KQKLVQTQGT KEKVYEATIE EKTKEYIFLR LSRECCEELN LRPDCDTQVE LQFQLNRLPL 
CEMHYALDRI KDNGVLFPDI SMTPTIPWSP NRQWDEQLDP RLNAKQKEAV LAITTPLAIQ 
LPPVLIIGPY GTGKTFTLAQ AVKHILQQQE TRILICTHSN SAADLYIKDY LHPYVEAGNP 
QARPLRVYFR NRWVKTVHPV VHQYCLISSA HSTFQMPQKE DILKHRVVVV TLNTSQYLCQ 
LDLEPGFFTH ILLDEAAQAM ECETIMPLAL ATQNTRIVLA GDHMQLSPFV YSEFARERNL 
HVSLLDRLYE HYPAEFPCRI LLCENYRSHE AIINYTSELF YEGKLMASGK QPAHKDFYPL 
TFFTARGEDV QEKNSTAFYN NAEVFEVVER VEELRRKWPV AWGKLDDGSI GVVTPYADQV 
FRIRAELRKK RLSDVNVERV LNVQGKQFRV LFLSTVRTRH TCKHKQTPIK KKEQLLEDST 
EDLDYGFLSN YKLLNTAITR AQSLVAVVGD PIALCSIGRC RKFWERFIAL CHENSSLHGI 
TFEQIKAQLE ALELKKTYVL NPLAPEFIPR ALRLQHSGST NKQQQSPPKG KSLHHTQNDH 
FQNDGIVQPN PSVLIGNPIR AYTPPPPLGP HPNLGKSPSP VQRIDPHTGT SILYVPAVYG 
GNVVMSVPLP VPWTGYQGRF AVDPRIITHQ AAMAYNMNLL QTHGRGSPIP YGLGHHPPVT 
IGQPQNQHQE KDQHEQNRNG KSDTNNSGPE INKIRTPEKK PTEPKQVDLE SNPQNRSPES 
RPSVVYPSTK FPRKDNLNPR HINLPLPAPH AQYAIPNRHF HPLPQLPRPP FPIPQQHTLL 
NQQQNNLPEQ PNQIPPQPNQ VVQQQSQLNQ QPQQPPPQLS PAYQAGPNNA FFNSAVAHRP 
QSPPAEAVIP EQQPPPMLQE GHSPLRAIAQ PGPILPSHLN SFIDENPSGL PIGEALDRIH 
GSVALETLRQ QQARFQQWSE HHAFLSQGSV PYPHHHHPHL QHLPQPPLGL HQPPVRADWK 
LTSSAEDEVE TTYSRFQDLI RELSHRDQSE TRELAEMPPP QSRLLQYRQV QSRSPPAVPS 
PPSSTDHSSH FSNFNDNSRD IEVASNPAFP QRLPPQIFNS PFSLPSEHLA PPPLKYLAPD 
GAWTFANLQQ NHLMGPGFPY GLPPLPHRPP QNPFVQIQNH QHAIGQEPFH PLSSRTVSSS 
SLPSLEEYEP RGPGRPLYQR RISSSSVQPC SEEVSTPQDS LAQCKELQDH SNQSSFNFSS 
PESWVNTTSS TPYQNIPCNG SSRTAQPREL IAPPKTVKPP EDQLKSENLE VSSSFNYSVL 
QHLGQFPPLM PNKQIAESAN SSSPQSSAGG KPAMSYASAL RAPPKPRPPP EQAKKSSDPL 
SLFQELSLGS SSGSNGFYSY FK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.