Details for: CDC25B

Gene ID: 994

Symbol: CDC25B

Ensembl ID: ENSG00000101224

Description: cell division cycle 25B

Associated with

Other Information

Genular Protein ID: 1308964814

Symbol: MPIP2_HUMAN

Name: M-phase inducer phosphatase 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1836978

Title: Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins.

PubMed ID: 1836978

DOI: 10.1016/0092-8674(91)90294-9

PubMed ID: 1662986

Title: An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells.

PubMed ID: 1662986

PubMed ID: 9188863

Title: Alternative splicing of the human CDC25B tyrosine phosphatase. Possible implications for growth control?

PubMed ID: 9188863

DOI: 10.1038/sj.onc.1201063

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11333986

Title: Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase.

PubMed ID: 11333986

DOI: 10.1038/35075107

PubMed ID: 12400006

Title: Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation.

PubMed ID: 12400006

DOI: 10.1038/sj.onc.1205870

PubMed ID: 15150265

Title: Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function.

PubMed ID: 15150265

DOI: 10.1074/jbc.m404728200

PubMed ID: 15128871

Title: Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.

PubMed ID: 15128871

DOI: 10.1242/jcs.01108

PubMed ID: 15311285

Title: Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase.

PubMed ID: 15311285

DOI: 10.1038/ncb1165

PubMed ID: 15908796

Title: CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis.

PubMed ID: 15908796

DOI: 10.4161/cc.4.6.1716

PubMed ID: 15629715

Title: MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation.

PubMed ID: 15629715

DOI: 10.1016/j.molcel.2004.11.021

PubMed ID: 17332740

Title: Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis.

PubMed ID: 17332740

DOI: 10.1038/sj.emboj.7601637

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 10543950

Title: Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.

PubMed ID: 10543950

DOI: 10.1006/jmbi.1999.3168

Sequence Information:

  • Length: 580
  • Mass: 64987
  • Checksum: EDE24B0E84AC1BE3
  • Sequence:
  • MEVPQPEPAP GSALSPAGVC GGAQRPGHLP GLLLGSHGLL GSPVRAAASS PVTTLTQTMH 
    DLAGLGSETP KSQVGTLLFR SRSRLTHLSL SRRASESSLS SESSESSDAG LCMDSPSPMD 
    PHMAEQTFEQ AIQAASRIIR NEQFAIRRFQ SMPVRLLGHS PVLRNITNSQ APDGRRKSEA 
    GSGAASSSGE DKENDGFVFK MPWKPTHPSS THALAEWASR REAFAQRPSS APDLMCLSPD 
    RKMEVEELSP LALGRFSLTP AEGDTEEDDG FVDILESDLK DDDAVPPGME SLISAPLVKT 
    LEKEEEKDLV MYSKCQRLFR SPSMPCSVIR PILKRLERPQ DRDTPVQNKR RRSVTPPEEQ 
    QEAEEPKARV LRSKSLCHDE IENLLDSDHR ELIGDYSKAF LLQTVDGKHQ DLKYISPETM 
    VALLTGKFSN IVDKFVIVDC RYPYEYEGGH IKTAVNLPLE RDAESFLLKS PIAPCSLDKR 
    VILIFHCEFS SERGPRMCRF IRERDRAVND YPSLYYPEMY ILKGGYKEFF PQHPNFCEPQ 
    DYRPMNHEAF KDELKTFRLK TRSWAGERSR RELCSRLQDQ

Genular Protein ID: 2543048274

Symbol: E1YMX4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 427
  • Mass: 49473
  • Checksum: C05C71DDE701A375
  • Sequence:
  • MDSPSPMDPH MAEQTFEQAI QAASRIIRNE QFAIRRFQSM PDGFVFKMPW KPTHPSSTHA 
    LAEWASRREA FAQRPSSAPD LMCLSPDRKM EVEELSPLAL GRFSLTPAEG DTEEDDGFVD 
    ILESDLKDDD AVPPGMESLI SAPLVKTLEK EEEKDLVMYS KCQRLFRSPS MPCSVIRPIL 
    KRLERPQDRD TPVQNKRRRS VTPPEEQQEA EEPKARVLRS KSLCHDEIEN LLDSDHRELI 
    GDYSKAFLLQ TVDGKHQDLK YISPETMVAL LTGKFSNIVD KFVIVDCRYP YEYEGGHIKT 
    AVNLPLERDA ESFLLKSPIA PCSLDKRVIL IFHCEFSSER GPRMCRFIRE RDRAVNDYPS 
    LYYPEMYILK GGYKEFFPQH PNFCEPQDYR PMNHEAFKDE LKTFRLKTRS WAGERSRREL 
    CSRLQDQ

Genular Protein ID: 770630232

Symbol: B3KS38_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 468
  • Mass: 53705
  • Checksum: 9C8F1C64B4285698
  • Sequence:
  • MDSPSPMDPH MAEQTFEQAI QAASRIIRNE QFAIRRFQSM PVRLLGHSPV LRNITNSQAP 
    DGRRKSEAGS GAASSSGEDK ENDGFVFKMP WKPTHPSSTH ALAEWASRRE AFAQRPSSAP 
    DLMCLSPDRK MEVEELSPLA LGRFSLTPAE GDTEEDDGFV DILESDLKDD DAVPPGMESL 
    ISAPLVKTLE KEEEKDLVMY SKCQRLFRSP SMPCSVIRPI LKRLERPQDR DTPVQNKRRR 
    SVTPPEEQQE AEEPKARVLR SKSLCHDEIE NLLDSDHREL IGDYSKAFLL QTVDGKHQDL 
    KYISPETMVA LLTGKFSNIV DKFVIVDCRY PYEYEGGHIK TAVNLPLERD AESFLLKSPI 
    APCSLDKRVI LIFHCEFSSE RGPRMCRFIR ERDRAVNDYP SLYYPEMYIL KGGYKEFFPQ 
    HPNFCEPQDY RPMNHEAFKD ELKTFRLKTR SWAGERSRRE LCSRLQDQ

Genular Protein ID: 745472377

Symbol: B4DRC3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 502
  • Mass: 57339
  • Checksum: A3E0062FF9FA875B
  • Sequence:
  • MHSRSRLTHL SLSRRASESS LSSESSESSD AGLCMDSPSP MDPHMAEQTF EQAIQAASRI 
    IRNEQFAIRR FQSMPVRLLG HSPVLRNITN SQAPDGRRKS EAGSGAASSS GEDKENDGFV 
    FKMPWKPTHP SSTHALAEWA SRREAFAQRP SSAPDLMCLS PDRKMEVEEL SPLALGRFSL 
    TPAEGDTEED DGFVDILESD LKDDDAVPPG MESLISAPLV KTLEKEEEKD LVMYSKCQRL 
    FRSPSMPCSV IRPILKRLER PQDRDTPVQN KRRRSVTPPE EQQEAEEPKA RVLRSKSLCH 
    DEIENLLDSD HRELIGDYSK AFLLQTVDGK HQDLKYISPE TMVALLTGKF SNIVDKFVIV 
    DCRYPYEYEG GHIKTAVNLP LERDAESFLL KSPIAPCSLD KRVILIFHCE FSSERGPRMC 
    RFIRERDRAV NDYPSLYYPE MYILKGGYKE FFPQHPNFCE PQDYRPMNHE AFKDELKTFR 
    LKTRSWAGER SRRELCSRLQ DQ

Genular Protein ID: 659168238

Symbol: B4DQZ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 489
  • Mass: 55989
  • Checksum: 303CF665BBB0DC19
  • Sequence:
  • MHSETPKSQV GTLLFRSRSR LTHLSLSRRA SESSLSSESS ESSDAGLCMD SPSPMDPHMA 
    EQTFEQAIQA ASRIIRNEQF AIRRFQSMPV RLLGHSPVLR NITNSQAPDG RRKSEAGSGA 
    ASSSGEDKEN DGFVFKMPWK PTHPSSTHAL AEWASRREAF AQRPSSAPDL MCLSPDRKME 
    VEELSPLALG RFSLTPAEGD TEEDDGFVDI LESDLKDLVM YSKCQRLFRS PSMPCSVIRP 
    ILKRLERPQD RDTPVQNKRR RSVTPPEEQQ EAEEPKARVL RSKSLCHDEI ENLLDSDHRE 
    LIGDYSKAFL LQTVDGKHQD LKYISPETMV ALLTGRFSNI VDKFVIVDCR YPYEYEGGHI 
    KTAVNLPLER DAESFLLKSP IAPCSLDKRV ILIFHCEFSS ERGPRMCRFI RERDRAVNDY 
    PSLYYPEMYI LKGGYKEFFP QHPNFCEPQD YRPMDHEAFK DELKTFRLKT RSWAGERSRR 
    ELCSRLQDQ

Genular Protein ID: 3246284728

Symbol: Q6MZW8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 412
  • Mass: 47875
  • Checksum: 2C0A833DA3D8C2CA
  • Sequence:
  • FEQAIQAASR IIRNEQFAIR RFQSMPDGFV FKMPWKPTHP SSTHALAEWA SRREAFAQRP 
    SSAPDLMCLS PDRKMEVEEL SPLALGRFSL TPAEGDTEED DGFVDILESD LKDDDAVPPD 
    MESLISAPLV KTLEKEEEKD LVMYSKCQRL FRSPSMPCSV IRPILKRLER PQDRDTPVQN 
    KRRRSVTPPE EQQEAEEPKA RVLRSKSLCH DEIENLLDSD HRELIGDYSK AFLLQTVDGK 
    HQDLKYISPE TMVALLTGKF SNIVDKFVIV DCRYPYEYEG GHIKTAVNLP LERDAESFLL 
    KSPIAPCSLD KRVILIFHCE FSSERGPRMC RFIRERDRAV NDYPSLYYPE MYILKGGYKE 
    FFPQHPNFCE PQDYRPMNHE AFKDELKTFR LKTRSWAGER SRRELCSRLQ DQ

Genular Protein ID: 1332620993

Symbol: G8JLH2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 489
  • Mass: 55960
  • Checksum: F2561B9EFAD9DC01
  • Sequence:
  • MHSETPKSQV GTLLFRSRSR LTHLSLSRRA SESSLSSESS ESSDAGLCMD SPSPMDPHMA 
    EQTFEQAIQA ASRIIRNEQF AIRRFQSMPV RLLGHSPVLR NITNSQAPDG RRKSEAGSGA 
    ASSSGEDKEN DGFVFKMPWK PTHPSSTHAL AEWASRREAF AQRPSSAPDL MCLSPDRKME 
    VEELSPLALG RFSLTPAEGD TEEDDGFVDI LESDLKDLVM YSKCQRLFRS PSMPCSVIRP 
    ILKRLERPQD RDTPVQNKRR RSVTPPEEQQ EAEEPKARVL RSKSLCHDEI ENLLDSDHRE 
    LIGDYSKAFL LQTVDGKHQD LKYISPETMV ALLTGKFSNI VDKFVIVDCR YPYEYEGGHI 
    KTAVNLPLER DAESFLLKSP IAPCSLDKRV ILIFHCEFSS ERGPRMCRFI RERDRAVNDY 
    PSLYYPEMYI LKGGYKEFFP QHPNFCEPQD YRPMNHEAFK DELKTFRLKT RSWAGERSRR 
    ELCSRLQDQ

Genular Protein ID: 2862378060

Symbol: B4DIG0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 516
  • Mass: 58884
  • Checksum: 862ADAFD01CC5A80
  • Sequence:
  • MHSETPKSQV GTLLFRSRSR LTHLSLSRRA SESSLSSESS ESSDAGLCMD SPSPMDPHMA 
    EQTFEQAIQA ASRIIRNEQF AIRRFQSMPV RLLGHSPVLR NITNSQAPDG RRKSEAGSGA 
    ASSSGEDKEN DGFVFKMPWK PTHPSSTHAL AEWASRREAF AQRPSSAPDL MCLSPDRKME 
    VEELSPLALG RFSLTPAEGD TEEDDGFVDI LESDLKDDDA VPPGMESLIS APLVKTLEKE 
    EEKDLVMYSK CQRLFRSPSM PCSVIRPILK RLERPQDRDT PVQNKRRRSV TPPEEQQEAE 
    EPKARVLRSK SLCHDEIENL LDSDHRELIG DYSKAFLLQT VDGKHQDLKY ISPETMVALL 
    TGKFSNIVDK FVIVDCRYPY EYEGGHIKTA VNLPLERDAE SFLLKSPIAP CSLDKRVILI 
    FHCEFSSERG PRMCRFIRER DRAVNDYPSL YYPEMYILKG GYKEFFPQHP NFCEPQDYRP 
    MNHEAFKDEL KTFRLKTRSW AGERSRRELC SRLQDQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.