Details for: MVP

Gene ID: 9961

Symbol: MVP

Ensembl ID: ENSG00000013364

Description: major vault protein

Associated with

Other Information

Genular Protein ID: 828913288

Symbol: MVP_HUMAN

Name: Major vault protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7585126

Title: The drug resistance-related protein LRP is the human major vault protein.

PubMed ID: 7585126

DOI: 10.1038/nm0695-578

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11071864

Title: Cloning and initial analysis of the human multidrug resistance-related MVP/LRP gene promoter.

PubMed ID: 11071864

DOI: 10.1006/bbrc.2000.3782

PubMed ID: 11297743

Title: A small upstream open reading frame causes inhibition of human major vault protein expression from a ubiquitous mRNA splice variant.

PubMed ID: 11297743

DOI: 10.1016/s0014-5793(01)02318-3

PubMed ID: 10551828

Title: Vaults and telomerase share a common subunit, TEP1.

PubMed ID: 10551828

DOI: 10.1074/jbc.274.46.32712

PubMed ID: 12177006

Title: PTEN associates with the vault particles in HeLa cells.

PubMed ID: 12177006

DOI: 10.1074/jbc.m207608200

PubMed ID: 15133037

Title: The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling.

PubMed ID: 15133037

DOI: 10.1074/jbc.m313955200

PubMed ID: 16815308

Title: A novel human zinc finger protein ZNF540 interacts with MVP and inhibits transcriptional activities of the ERK signal pathway.

PubMed ID: 16815308

DOI: 10.1016/j.bbrc.2006.06.076

PubMed ID: 16441665

Title: Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling.

PubMed ID: 16441665

DOI: 10.1111/j.1742-4658.2006.05112.x

PubMed ID: 16418217

Title: The major vault protein is responsive to and interferes with interferon-gamma-mediated STAT1 signals.

PubMed ID: 16418217

DOI: 10.1242/jcs.02773

PubMed ID: 18809583

Title: Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1.

PubMed ID: 18809583

DOI: 10.1128/mcb.00244-08

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16373071

Title: Solution structure of a two-repeat fragment of major vault protein.

PubMed ID: 16373071

DOI: 10.1016/j.jmb.2005.11.064

PubMed ID: 28895081

Title: Novel de novo KCND3 mutation in a Japanese patient with intellectual disability, cerebellar ataxia, myoclonus, and dystonia.

PubMed ID: 28895081

DOI: 10.1007/s12311-017-0883-4

Sequence Information:

  • Length: 893
  • Mass: 99327
  • Checksum: 6FEE5545B0A3FE65
  • Sequence:
  • MATEEFIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPMRM VTVPPRHYCT 
    VANPVSRDAQ GLVLFDVTGQ VRLRHADLEI RLAQDPFPLY PGEVLEKDIT PLQVVLPNTA 
    LHLKALLDFE DKDGDKVVAG DEWLFEGPGT YIPRKEVEVV EIIQATIIRQ NQALRLRARK 
    ECWDRDGKER VTGEEWLVTT VGAYLPAVFE EVLDLVDAVI LTEKTALHLR ARRNFRDFRG 
    VSRRTGEEWL VTVQDTEAHV PDVHEEVLGV VPITTLGPHN YCVILDPVGP DGKNQLGQKR 
    VVKGEKSFFL QPGEQLEQGI QDVYVLSEQQ GLLLRALQPL EEGEDEEKVS HQAGDHWLIR 
    GPLEYVPSAK VEVVEERQAI PLDENEGIYV QDVKTGKVRA VIGSTYMLTQ DEVLWEKELP 
    PGVEELLNKG QDPLADRGEK DTAKSLQPLA PRNKTRVVSY RVPHNAAVQV YDYREKRARV 
    VFGPELVSLG PEEQFTVLSL SAGRPKRPHA RRALCLLLGP DFFTDVITIE TADHARLQLQ 
    LAYNWHFEVN DRKDPQETAK LFSVPDFVGD ACKAIASRVR GAVASVTFDD FHKNSARIIR 
    TAVFGFETSE AKGPDGMALP RPRDQAVFPQ NGLVVSSVDV QSVEPVDQRT RDALQRSVQL 
    AIEITTNSQE AAAKHEAQRL EQEARGRLER QKILDQSEAE KARKELLELE ALSMAVESTG 
    TAKAEAESRA EAARIEGEGS VLQAKLKAQA LAIETEAELQ RVQKVRELEL VYARAQLELE 
    VSKAQQLAEV EVKKFKQMTE AIGPSTIRDL AVAGPEMQVK LLQSLGLKST LITDGSTPIN 
    LFNTAFGLLG MGPEGQPLGR RVASGPSPGE GISPQSAQAP QAPGDNHVVP VLR

Genular Protein ID: 2617102178

Symbol: X5DNU0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 24722188

Title: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

PubMed ID: 24722188

Sequence Information:

  • Length: 833
  • Mass: 92522
  • Checksum: 8F7DE13AC03CA936
  • Sequence:
  • MATEEFIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPMRM VTVPPRHYCT 
    VANPVSRDAQ GLVLFDVTGQ VRLRHADLEI RLAQDPFPLY PGEVLEKDIT PLQVVLPNTA 
    LHLKALLDFE DKDGDKVVAG DEWLFEGPGT YIPRKEVEVV EIIQATIIRQ NQALRLRARK 
    ECWDRDGKER VTGEEWLVTT VGAYLPAVFE EVLDLVDAVI LTEKTALHLR ARRNFRDFRG 
    VSRRTGEEWL VTVQDTEAHV PDVHEEVLGV VPITTLGPHN YCVILDPVGP DGKNQLGQKR 
    VVKGEKSFFL QPGEQLEQGI QDVYVLSEQQ GLLLRALQPL EEGEDEEKVS HQAGDHWLIR 
    GPLEYVPSAK VEVVEERQAI PLDENEGIYV QDVKTGKVRA VIGSTYMLTQ DEVLWEKELP 
    PGVEELLNKG QDPLADRGEK DTAKSLQPLA PRNKTRVVSY RVPHNAAVQV YDYREKRARV 
    VFGPELVSLG PEEQFTVLSL SAGRPKRPHA RRALCLLLGP DFFTDVITIE TADHARLQLQ 
    LAYNWHFEVN DRKDPQETAK LFSVPDFVGD ACKAIASRVR GAVASVTFDD FHKNSARIIR 
    TAVFGFETSE AKGPDGMALP RPRDQAVFPQ NGLVVSSVDV QSVEPVDQRT RDALQRSVQL 
    AIEITTNSQE AAAKHEAQRL EQEARGRLER QKILDQSEAE KARKELLELE ALSMAVESTG 
    TAKAEAESRA EAARIEGEGS VLQASTIRDL AVAGPEMQVK LLQSLGLKST LITDGSTPIN 
    LFNTAFGLLG MGPEGQPLGR RVASGPSPGE GISPQSAQAP QAPGDNHVVP VLR

Genular Protein ID: 2797845696

Symbol: X5D7K9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 24722188

Title: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

PubMed ID: 24722188

Sequence Information:

  • Length: 827
  • Mass: 91959
  • Checksum: 5717BE2B96165FE1
  • Sequence:
  • MATEEFIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPMRM VTVPPRHYCT 
    VANPVSRDAQ GLVLFDVTGQ VRLRHADLEI RLAQDPFPLY PGEVLEKDIT PLQVVLPNTA 
    LHLKALLDFE DKDGDKVVAG DEWLFEGPGT YIPRKEVEVV EIIQATIIRQ NQALRLRARK 
    ECWDRDGKER VTGEEWLVTT VGAYLPAVFE EVLDLVDAVI LTEKTALHLR ARRNFRDFRG 
    VSRRTGEEWL VTVQDTEAHV PDVHEEVLGV VPITTLGPHN YCVILDPVGP DGKNQLGQKR 
    VVKGEKSFFL QPGEQLEQGI QDVYVLSEQQ GLLLRALQPL EEGEDEEKVS HQAGDHWLIR 
    GPLEYVPSAK VEVVEERQAI PLDENEGIYV QDVKTGKVRA VIGSTYMLTQ DEVLWEKELP 
    PGVEELLNKG QDPLADRGEK DTAKSLQPLA PRNKTRVVSY RVPHNAAVQV YDYREKRARH 
    FEVNDRKDPQ ETAKLFSVPD FVGDACKAIA SRVRGAVASV TFDDFHKNSA RIIRTAVFGF 
    ETSEAKGPDG MALSRPRDQA VFPQNGLVVS SVDVQSVEPV DQRTRDALQR SVQLAIEITT 
    NSQEAAAKHE AQRLEQEARG RLERQKILDQ SEAEKARKEL LELEALSMAV ESTGTAKAEA 
    ESRAEAARIE GEGSVLQAKL KAQALAIETE AELQRVQKVR ELELVYARAQ LELEVSKAQQ 
    LAEVEVKKFK QMTEAIGPST IRDLAVAGPE MQVKLLQSLG LKSTLITDGS TPINLFNTAF 
    GLLGMGPEGQ PLGRRVASGP SPGEGISPQS AQAPQAPGDN HVVPVLR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.