TNFSF15 | ENSG00000181634 | NCBI 9966

Details for: TNFSF15

Gene ID: 9966

Symbol: TNFSF15

Ensembl ID: ENSG00000181634

Description: TNF superfamily member 15

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Tnfr2 non-canonical nf-kb pathway
(R-HSA-5668541)
Tnfs bind their physiological receptors
(R-HSA-5669034)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Activation of nf-kappab-inducing kinase activity
(GO:0007250)
Cytokine activity
(GO:0005125)
Extracellular space
(GO:0005615)
Immune response
(GO:0006955)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Tumor necrosis factor receptor binding
(GO:0005164)

Other Information

Proteins

Tumor necrosis factor ligand superfamily member 15

Genular Protein ID: 360600588

Symbol: TNF15_HUMAN

Name: Tumor necrosis factor ligand superfamily member 15

UniProtKB Accession Codes:

O95150 Q3SX69 Q5VJK8 Q5VWH1 Q8NFE9

Database IDs:

Citations:

PubMed ID: 9872942

Title: VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo.

PubMed ID: 9872942

DOI: 10.1096/fasebj.13.1.181

PubMed ID: 11923219

Title: A novel secreted splice variant of vascular endothelial cell growth inhibitor.

PubMed ID: 11923219

DOI: 10.1096/fj.01-0757fje

PubMed ID: 11911831

Title: TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.

PubMed ID: 11911831

DOI: 10.1016/s1074-7613(02)00283-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9434163

Title: Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells.

PubMed ID: 9434163

DOI: 10.1016/s0378-1119(97)00509-x

PubMed ID: 10597252

Title: VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth.

PubMed ID: 10597252

DOI: 10.1038/sj.onc.1203059

PubMed ID: 17935696

Title: X-ray crystal structure of TNF ligand family member TL1A at 2.1A.

PubMed ID: 17935696

DOI: 10.1016/j.bbrc.2007.09.097

PubMed ID: 21300286

Title: Decoy strategies: the structure of TL1A:DcR3 complex.

PubMed ID: 21300286

DOI: 10.1016/j.str.2010.12.004

Sequence Information:

Length: 251
Mass: 28087
Checksum: 65ED70E367E3446D
Sequence:

MAEDLGLSFG ETASVEMLPE HGSCRPKARS SSARWALTCC LVLLPFLAGL TTYLLVSQLR 
AQGEACVQFQ ALKGQEFAPS HQQVYAPLRA DGDKPRAHLT VVRQTPTQHF KNQFPALHWE 
HELGLAFTKN RMNYTNKFLL IPESGDYFIY SQVTFRGMTS ECSEIRQAGR PNKPDSITVV 
ITKVTDSYPE PTQLLMGTKS VCEVGSNWFQ PIYLGAMFSL QEGDKLMVNV SDISLVDYTK 
EDKTFFGAFL L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TNFSF15

Associated with

Other Information

VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo. PubMed ID: 9872942

A novel secreted splice variant of vascular endothelial cell growth inhibitor. PubMed ID: 11923219

TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. PubMed ID: 11911831

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

DNA sequence and analysis of human chromosome 9. PubMed ID: 15164053

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells. PubMed ID: 9434163

VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth. PubMed ID: 10597252

X-ray crystal structure of TNF ligand family member TL1A at 2.1A. PubMed ID: 17935696

Decoy strategies: the structure of TL1A:DcR3 complex. PubMed ID: 21300286