Details for: HNRNPDL

Gene ID: 9987

Symbol: HNRNPDL

Ensembl ID: ENSG00000152795

Description: heterogeneous nuclear ribonucleoprotein D like

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 4.99
    Marker Score: 10,539
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 4.35
    Marker Score: 148,122
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 4.18
    Marker Score: 17,413
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 3.96
    Marker Score: 12,503
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 3.96
    Marker Score: 52,239
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 3.94
    Marker Score: 8,255
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 3.93
    Marker Score: 208,021
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 3.9
    Marker Score: 1,438
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 3.75
    Marker Score: 5,781
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.74
    Marker Score: 37,039
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 3.69
    Marker Score: 10,342
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.62
    Marker Score: 42,085
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.61
    Marker Score: 8,829
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 3.61
    Marker Score: 10,532
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 3.61
    Marker Score: 15,468
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 3.47
    Marker Score: 3,356
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.45
    Marker Score: 824
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 3.44
    Marker Score: 8,400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.44
    Marker Score: 22,357
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 3.37
    Marker Score: 4,966
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 3.34
    Marker Score: 1,363
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 3.34
    Marker Score: 3,142
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 3.32
    Marker Score: 16,330
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 3.27
    Marker Score: 2,473
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 3.23
    Marker Score: 3,448
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 3.23
    Marker Score: 2,835
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 3.22
    Marker Score: 3,176
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 3.21
    Marker Score: 12,437
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 3.19
    Marker Score: 2,408
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 3.15
    Marker Score: 5,920
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 3.12
    Marker Score: 2,790
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 3.12
    Marker Score: 3,768
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 3.12
    Marker Score: 8,607
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 3.11
    Marker Score: 2,769
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.11
    Marker Score: 3,765
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 3.11
    Marker Score: 7,437
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 3.09
    Marker Score: 5,523
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 3.09
    Marker Score: 5,067
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 3.08
    Marker Score: 2,523
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 3.08
    Marker Score: 5,283
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 3.05
    Marker Score: 616
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 3.05
    Marker Score: 668
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 3.05
    Marker Score: 1,062
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 3.04
    Marker Score: 2,561
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.04
    Marker Score: 3,440
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 3.03
    Marker Score: 1,903
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 3.02
    Marker Score: 40,515
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 3.01
    Marker Score: 4,264
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 3.01
    Marker Score: 1,462
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 2.99
    Marker Score: 1,348
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 2.99
    Marker Score: 1,752
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.99
    Marker Score: 3,250
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.97
    Marker Score: 4,001
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 2.97
    Marker Score: 1,741
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 2.97
    Marker Score: 1,966
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 2.97
    Marker Score: 17,587
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 2.94
    Marker Score: 3,445
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 2.94
    Marker Score: 673
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.92
    Marker Score: 2,295
  • Cell Name: theca cell (CL0000503)
    Fold Change: 2.92
    Marker Score: 2,093
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.91
    Marker Score: 2,203
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.91
    Marker Score: 7,802
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.9
    Marker Score: 162,373
  • Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
    Fold Change: 2.89
    Marker Score: 1,313
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 2.88
    Marker Score: 2,780
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 2.87
    Marker Score: 1,930
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 2.87
    Marker Score: 3,954
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.87
    Marker Score: 11,047
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.86
    Marker Score: 1,724
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.85
    Marker Score: 2,671
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.85
    Marker Score: 1,154
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.83
    Marker Score: 5,549
  • Cell Name: tendon cell (CL0000388)
    Fold Change: 2.83
    Marker Score: 696
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 2.83
    Marker Score: 1,310
  • Cell Name: basal cell (CL0000646)
    Fold Change: 2.82
    Marker Score: 3,644
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 2.82
    Marker Score: 2,064
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 2.82
    Marker Score: 977
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 2.81
    Marker Score: 2,715
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 2.81
    Marker Score: 802
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 2.79
    Marker Score: 3,450
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.79
    Marker Score: 2,035
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.78
    Marker Score: 1,198
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 2.77
    Marker Score: 1,643
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.76
    Marker Score: 1,377
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 2.75
    Marker Score: 1,985
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 2.75
    Marker Score: 17,895
  • Cell Name: lung neuroendocrine cell (CL1000223)
    Fold Change: 2.74
    Marker Score: 774
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 2.74
    Marker Score: 956
  • Cell Name: visceromotor neuron (CL0005025)
    Fold Change: 2.74
    Marker Score: 799
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: 2.74
    Marker Score: 777
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.74
    Marker Score: 2,156
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 2.73
    Marker Score: 2,411
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 2.73
    Marker Score: 967
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.73
    Marker Score: 2,447
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 2.73
    Marker Score: 2,135
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 2.72
    Marker Score: 6,919
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 2.72
    Marker Score: 721
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.72
    Marker Score: 6,861
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.72
    Marker Score: 2,759
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 2.72
    Marker Score: 715

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** HNRNPDL is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, which is a group of proteins that bind to RNA and play crucial roles in various cellular processes, including transcription, splicing, and translation. HNRNPDL shares similarities with other hnRNP proteins, such as hnRNP D, but exhibits distinct characteristics, including its ability to interact with various RNA species and proteins. The protein's expression is widespread, with significant levels found in immune cells, where it is thought to play a role in regulating gene expression in response to cytokine stimulation. **Pathways and Functions:** HNRNPDL is involved in several key pathways, including cytokine signaling in the immune system, DNA binding, and gene and protein expression by the JAK-STAT signaling pathway after IL-12 stimulation. The protein's interaction with RNA and proteins allows it to modulate gene expression, influencing the transcriptional activity of various genes involved in immune responses. Specifically, HNRNPDL has been shown to interact with RNA-binding proteins, such as AUF1, and to regulate the expression of genes involved in cytokine signaling, including those involved in the IL-12 family signaling pathway. **Clinical Significance:** The clinical significance of HNRNPDL lies in its role in regulating immune responses, particularly in the context of cytokine signaling. Dysregulation of HNRNPDL expression or function may contribute to immune-related disorders, such as autoimmune diseases, where the balance between pro-inflammatory and anti-inflammatory cytokines is disrupted. Furthermore, HNRNPDL's involvement in gene expression regulation may also have implications for cancer, where altered gene expression patterns are a hallmark of tumorigenesis. Understanding the mechanisms by which HNRNPDL regulates gene expression and immune responses may provide insights into the development of novel therapeutic strategies for immune-related disorders. In conclusion, HNRNPDL is a multifunctional protein that plays a crucial role in regulating gene expression, particularly in the context of immune response. Its involvement in cytokine signaling, DNA binding, and gene expression regulation highlights its importance in modulating immune responses. Further research is needed to fully elucidate the mechanisms by which HNRNPDL regulates gene expression and immune responses, with implications for the development of novel therapeutic strategies for immune-related disorders.

Genular Protein ID: 3322387566

Symbol: HNRDL_HUMAN

Name: Heterogeneous nuclear ribonucleoprotein D-like

UniProtKB Accession Codes:

O14979 Q6SPF2 Q7KZ74 Q7KZ75 Q96IM0 Q96S43

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 12 EMDB 1 EPD 1 Ensembl 8 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9538234

Title: Cloning and characterization of a cDNA encoding a novel heterogeneous nuclear ribonucleoprotein-like protein and its expression in myeloid leukemia cells.

PubMed ID: 9538234

DOI: 10.1093/oxfordjournals.jbchem.a021964

PubMed ID: 10072754

Title: Two forms of expression and genomic structure of the human heterogeneous nuclear ribonucleoprotein D-like JKTBP gene (HNRPDL).

PubMed ID: 10072754

DOI: 10.1016/s0378-1119(99)00020-7

PubMed ID: 11705999

Title: Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA.

PubMed ID: 11705999

DOI: 10.1074/jbc.m108477200

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15190078

Title: Regulation of murine cytochrome c oxidase Vb gene expression during myogenesis: YY-1 and heterogeneous nuclear ribonucleoprotein D-like protein (JKTBP1) reciprocally regulate transcription activity by physical interaction with the BERF-1/ZBP-89 factor.

PubMed ID: 15190078

DOI: 10.1074/jbc.m403160200

PubMed ID: 9524220

Title: Molecular cloning of the cDNA encoding A + U-rich element RNA binding factor.

PubMed ID: 9524220

DOI: 10.1016/s0167-4781(97)00223-6

PubMed ID: 12406575

Title: Interactions of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its domains with high-affinity binding sites.

PubMed ID: 12406575

DOI: 10.1016/s0378-1119(02)00926-5

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24647604

Title: A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G).

PubMed ID: 24647604

DOI: 10.1093/hmg/ddu127

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 420
  • Mass: 46438
  • Checksum: 00F631863859D0CA
  • Sequence:
    • MEVPPRLSHV PPPLFPSAPA TLASRSLSHW RPRPPRQLAP LLPSLAPSSA RQGARRAQRH 
VTAQQPSRLA GGAAIKGGRR RRPDLFRRHF KSSSIQRSAA AAAATRTARQ HPPADSSVTM 
EDMNEYSNIE EFAEGSKINA SKNQQDDGKM FIGGLSWDTS KKDLTEYLSR FGEVVDCTIK 
TDPVTGRSRG FGFVLFKDAA SVDKVLELKE HKLDGKLIDP KRAKALKGKE PPKKVFVGGL 
SPDTSEEQIK EYFGAFGEIE NIELPMDTKT NERRGFCFIT YTDEEPVKKL LESRYHQIGS 
GKCEIKVAQP KEVYRQQQQQ QKGGRGAAAG GRGGTRGRGR GQGQNWNQGF NNYYDQGYGN 
YNSAYGGDQN YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY

Genular Protein ID: 1366536481

Symbol: A0A087WUK2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WUK2

Database IDs:

ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EPD 1 Ensembl 2 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 4 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 363
  • Mass: 40040
  • Checksum: F59C1E61EAB22BC2
  • Sequence:
    • MEVPPRLSHV PPPLFPSAPA TLASRSLSHW RPRPPRQLAP LLPSLAPSSA RQGARRAQRH 
VTAQQPSRLA GGAAIKGGRR RRPDLFRRHF KSSSIQRSAA AAAATRTARQ HPPADSSVTM 
EDMNEYSNIE EFAEGSKINA SKNQQDDGKM FIGGLSWDTS KKDLTEYLSR FGEVVDCTIK 
TDPVTGRSRG FGFVLFKDAA SVDKVLELKE HKLDGKLIDP KRAKALKGKE PPKKVFVGGL 
SPDTSEEQIK EYFGAFGEIE NIELPMDTKT NERRGFCFIT YTDEEPVKKL LESRYHQIGS 
GKCEIKVAQP KEVYRQQQQQ QKGGRGAAAG GRGGTRGRGR GQQSTYGKAS RGGGNHQNNY 
QPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.