**Key characteristics:**
- NR3C1P1 is a transmembrane protein that is approximately 130 amino acids long.
- It is a member of the NR3C1 family of nuclear receptors, which are known for their role in regulating inflammation and cell differentiation.
- NR3C1P1 is a ligand for the cytokine and chemokine receptor 3A (CCR3A).
**Pathways and functions:**
- NR3C1P1 is a key regulator of inflammation. It is expressed in cells that are activated by inflammatory stimuli, and it promotes the production of inflammatory cytokines and chemokines.
- In oligodendrocyte precursor cells, NR3C1P1 is expressed in oligodendrocytes, the cells that are responsible for the development of the central nervous system.
- In mesenchymal stem cells, NR3C1P1 is expressed in a subset of cells that are committed to becoming neurons and astrocytes.
- In retinal rod cells, NR3C1P1 is expressed in retinal rod cells, which are responsible for the function of the retina.
- In mast cells, NR3C1P1 is expressed in mast cells, which are involved in the inflammatory response.
**Clinical significance:**
- Mutations in NR3C1P1 have been linked to several human diseases, including multiple sclerosis, inflammatory bowel disease, and asthma.
- NR3C1P1 is a potential target for therapy in these diseases.
**Conclusion:**
NR3C1P1 is a versatile nuclear receptor that plays a critical role in inflammation and cell differentiation. Its expression and function are widely distributed, and it is involved in a variety of physiological and pathological processes.
Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
