Details for: RNU1 15P

Gene ID: 26858

Symbol: RNU1 15P

Ensembl ID: ENSG00000195024

Description: RNA, U1 small nuclear 15, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.0117
    Cell Significance Index: 0.1100
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0047
    Cell Significance Index: -0.0600
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0049
    Cell Significance Index: -0.0500
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0065
    Cell Significance Index: -0.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNU1 15P is classified as a pseudogene, meaning it does not encode a functional protein. Despite its non-coding status, this gene exhibits high expression levels in multiple cell types, suggesting its involvement in regulating gene expression or participating in cellular processes. Its expression is significantly higher in immune cells, such as B cells and T cells, which implies a potential role in immune system development or function. **Pathways and Functions:** The mechanisms underlying the functions of RNU1 15P remain poorly understood. However, several hypotheses have been proposed: 1. **Regulation of gene expression:** RNU1 15P may act as a non-coding RNA, influencing the expression of nearby genes through various mechanisms, such as RNA interference (RNAi) or microRNA-mediated regulation. 2. **Immunoregulation:** The high expression of RNU1 15P in immune cells suggests a potential role in modulating immune responses, possibly by regulating the expression of immune-related genes or influencing the activity of immune cells. 3. **Cellular differentiation:** RNU1 15P may play a role in the differentiation of immune cells, such as B cells and T cells, by regulating the expression of specific genes involved in their development. **Clinical Significance:** The clinical significance of RNU1 15P remains a topic of ongoing research. However, several potential implications have been proposed: 1. **Immunological disorders:** Abnormal expression of RNU1 15P may contribute to the development of immunological disorders, such as autoimmune diseases or immunodeficiency syndromes. 2. **Cancer:** The high expression of RNU1 15P in certain cancer types, such as lymphoma, suggests a potential role in tumorigenesis or tumor progression. 3. **Gene therapy:** Understanding the mechanisms underlying RNU1 15P expression may provide insights into the development of gene therapies targeting specific immune cells or pathways. In conclusion, while the functions of RNU1 15P remain unclear, its widespread expression across immune cells and other cell types suggests a significant role in regulating gene expression and immune system development. Further research is necessary to elucidate the mechanisms underlying its functions and to explore its clinical significance in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.