Details for: RNU6 413P

Gene ID: 106479748

Symbol: RNU6 413P

Ensembl ID: ENSG00000206842

Description: RNA, U6 small nuclear 413, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.1053
    Cell Significance Index: 1.2100
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.0054
    Cell Significance Index: 0.0600
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0050
    Cell Significance Index: -0.0600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0061
    Cell Significance Index: -0.0700
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0062
    Cell Significance Index: -0.0700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNU6 413P is a pseudogene, which implies that it lacks the ability to produce a functional protein. Despite this, pseudogenes can still play crucial roles in gene regulation, cellular differentiation, and immune responses. The RNU6 413P gene is significantly expressed in various cell types, including astrocytes, intestinal enteroendocrine cells, and neoplastic cells. This widespread expression suggests that RNU6 413P may be involved in maintaining cellular homeostasis, regulating cell growth, and modulating immune responses. **Pathways and Functions:** The exact mechanisms by which RNU6 413P exerts its effects are not fully understood. However, several studies have implicated this pseudogene in the regulation of alternative splicing, RNA processing, and gene expression. RNU6 413P has been shown to interact with other genes and non-coding RNAs (ncRNAs) to modulate their expression and function. For instance, RNU6 413P has been found to bind to and regulate the expression of genes involved in cell proliferation, differentiation, and survival. Furthermore, RNU6 413P may play a role in the regulation of immune responses by modulating the expression of genes involved in the immune system. One possible mechanism by which RNU6 413P exerts its effects is through the regulation of microRNA (miRNA) expression. miRNAs are small non-coding RNAs that play a crucial role in regulating gene expression by binding to and degrading messenger RNA (mRNA) molecules. RNU6 413P has been found to interact with miRNAs involved in immune responses, suggesting that this pseudogene may modulate the expression of genes involved in the immune system. **Clinical Significance:** The clinical significance of RNU6 413P is an area of active research. Given its widespread expression in various cell types, RNU6 413P may play a role in the development and progression of various diseases, including cancer. Neoplastic cells, which are characterized by uncontrolled growth and division, often exhibit aberrant expression of pseudogenes like RNU6 413P. This aberrant expression may contribute to the development and progression of cancer by disrupting normal cellular regulation and immune responses. Furthermore, RNU6 413P may also play a role in autoimmune diseases, such as multiple sclerosis and type 1 diabetes, where aberrant expression of pseudogenes has been implicated. In these diseases, RNU6 413P may contribute to the disruption of normal immune responses, leading to the development of autoimmune inflammation. In conclusion, the RNU6 413P gene is a complex and enigmatic pseudogene that plays a multifaceted role in regulating gene expression, cellular differentiation, and immune responses. Further research is necessary to fully elucidate the mechanisms by which RNU6 413P exerts its effects and to explore its clinical significance in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.