Details for: CL0000127

Cell ID: CL0000127

Cell Name: astrocyte

Contexts:

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.

Synonyms: astrocytic glia

Genes (max top 200)

(CSI Score: Combines effect size and statistical significance for astrocyte. A higher CSI Score generally indicates a more significant expression difference.)

  • 1. Gene Symbol: BMPR1A (ENSG00000107779)
    CSI Score: 6.57
    Ensembl ID: ENSG00000107779
  • 2. Gene Symbol: ALDOC (ENSG00000109107)
    CSI Score: 6.39
    Ensembl ID: ENSG00000109107
  • 3. Gene Symbol: ASPH (ENSG00000198363)
    CSI Score: 6.34
    Ensembl ID: ENSG00000198363
  • 4. Gene Symbol: BMPR1B (ENSG00000138696)
    CSI Score: 6.11
    Ensembl ID: ENSG00000138696
  • 5. Gene Symbol: ACACA (ENSG00000278540)
    CSI Score: 6.04
    Ensembl ID: ENSG00000278540
  • 6. Gene Symbol: ADCY2 (ENSG00000078295)
    CSI Score: 6.01
    Ensembl ID: ENSG00000078295
  • 7. Gene Symbol: BMP7 (ENSG00000101144)
    CSI Score: 5.89
    Ensembl ID: ENSG00000101144
  • 8. Gene Symbol: ABAT (ENSG00000183044)
    CSI Score: 5.85
    Ensembl ID: ENSG00000183044
  • 9. Gene Symbol: ABR (ENSG00000159842)
    CSI Score: 5.8
    Ensembl ID: ENSG00000159842
  • 10. Gene Symbol: AQP4 (ENSG00000171885)
    CSI Score: 5.75
    Ensembl ID: ENSG00000171885
  • 11. Gene Symbol: AK4 (ENSG00000162433)
    CSI Score: 5.65
    Ensembl ID: ENSG00000162433
  • 12. Gene Symbol: APBA2 (ENSG00000034053)
    CSI Score: 5.52
    Ensembl ID: ENSG00000034053
  • 13. Gene Symbol: ADCY8 (ENSG00000155897)
    CSI Score: 5.5
    Ensembl ID: ENSG00000155897
  • 14. Gene Symbol: APC (ENSG00000134982)
    CSI Score: 5.45
    Ensembl ID: ENSG00000134982
  • 15. Gene Symbol: BBS2 (ENSG00000125124)
    CSI Score: 5.42
    Ensembl ID: ENSG00000125124
  • 16. Gene Symbol: BCR (ENSG00000186716)
    CSI Score: 5.42
    Ensembl ID: ENSG00000186716
  • 17. Gene Symbol: ATP2B4 (ENSG00000058668)
    CSI Score: 5.35
    Ensembl ID: ENSG00000058668
  • 18. Gene Symbol: ARSB (ENSG00000113273)
    CSI Score: 5.32
    Ensembl ID: ENSG00000113273
  • 19. Gene Symbol: BMPR2 (ENSG00000204217)
    CSI Score: 5.28
    Ensembl ID: ENSG00000204217
  • 20. Gene Symbol: ATP2B2 (ENSG00000157087)
    CSI Score: 5.25
    Ensembl ID: ENSG00000157087
  • 21. Gene Symbol: ABCD2 (ENSG00000173208)
    CSI Score: 5.25
    Ensembl ID: ENSG00000173208
  • 22. Gene Symbol: ADARB2 (ENSG00000185736)
    CSI Score: 5.23
    Ensembl ID: ENSG00000185736
  • 23. Gene Symbol: ALK (ENSG00000171094)
    CSI Score: 5.19
    Ensembl ID: ENSG00000171094
  • 24. Gene Symbol: ANGPT1 (ENSG00000154188)
    CSI Score: 5.14
    Ensembl ID: ENSG00000154188
  • 25. Gene Symbol: ALCAM (ENSG00000170017)
    CSI Score: 5.13
    Ensembl ID: ENSG00000170017
  • 26. Gene Symbol: ZFHX3 (ENSG00000140836)
    CSI Score: 5.1
    Ensembl ID: ENSG00000140836
  • 27. Gene Symbol: ALDH1A1 (ENSG00000165092)
    CSI Score: 5.04
    Ensembl ID: ENSG00000165092
  • 28. Gene Symbol: AGT (ENSG00000135744)
    CSI Score: 5.02
    Ensembl ID: ENSG00000135744
  • 29. Gene Symbol: AGL (ENSG00000162688)
    CSI Score: 4.95
    Ensembl ID: ENSG00000162688
  • 30. Gene Symbol: APBA1 (ENSG00000107282)
    CSI Score: 4.95
    Ensembl ID: ENSG00000107282
  • 31. Gene Symbol: AMPH (ENSG00000078053)
    CSI Score: 4.91
    Ensembl ID: ENSG00000078053
  • 32. Gene Symbol: KIF1A (ENSG00000130294)
    CSI Score: 4.78
    Ensembl ID: ENSG00000130294
  • 33. Gene Symbol: AXL (ENSG00000167601)
    CSI Score: 4.75
    Ensembl ID: ENSG00000167601
  • 34. Gene Symbol: ALDH7A1 (ENSG00000164904)
    CSI Score: 4.74
    Ensembl ID: ENSG00000164904
  • 35. Gene Symbol: ABCA3 (ENSG00000167972)
    CSI Score: 4.74
    Ensembl ID: ENSG00000167972
  • 36. Gene Symbol: ADRA1A (ENSG00000120907)
    CSI Score: 4.71
    Ensembl ID: ENSG00000120907
  • 37. Gene Symbol: ATP1A2 (ENSG00000018625)
    CSI Score: 4.68
    Ensembl ID: ENSG00000018625
  • 38. Gene Symbol: ARRB1 (ENSG00000137486)
    CSI Score: 4.61
    Ensembl ID: ENSG00000137486
  • 39. Gene Symbol: AEBP1 (ENSG00000106624)
    CSI Score: 4.58
    Ensembl ID: ENSG00000106624
  • 40. Gene Symbol: APBB2 (ENSG00000163697)
    CSI Score: 4.58
    Ensembl ID: ENSG00000163697
  • 41. Gene Symbol: ASTN1 (ENSG00000152092)
    CSI Score: 4.55
    Ensembl ID: ENSG00000152092
  • 42. Gene Symbol: ATP6V0A1 (ENSG00000033627)
    CSI Score: 4.54
    Ensembl ID: ENSG00000033627
  • 43. Gene Symbol: ACTN2 (ENSG00000077522)
    CSI Score: 4.54
    Ensembl ID: ENSG00000077522
  • 44. Gene Symbol: ADGRB1 (ENSG00000181790)
    CSI Score: 4.41
    Ensembl ID: ENSG00000181790
  • 45. Gene Symbol: APLP1 (ENSG00000105290)
    CSI Score: 4.41
    Ensembl ID: ENSG00000105290
  • 46. Gene Symbol: APOE (ENSG00000130203)
    CSI Score: 4.39
    Ensembl ID: ENSG00000130203
  • 47. Gene Symbol: ASIC1 (ENSG00000110881)
    CSI Score: 4.35
    Ensembl ID: ENSG00000110881
  • 48. Gene Symbol: ATP1B2 (ENSG00000129244)
    CSI Score: 4.35
    Ensembl ID: ENSG00000129244
  • 49. Gene Symbol: BCL9 (ENSG00000116128)
    CSI Score: 4.33
    Ensembl ID: ENSG00000116128
  • 50. Gene Symbol: ADORA2B (ENSG00000170425)
    CSI Score: 4.19
    Ensembl ID: ENSG00000170425
  • 51. Gene Symbol: ARVCF (ENSG00000099889)
    CSI Score: 4.16
    Ensembl ID: ENSG00000099889
  • 52. Gene Symbol: ACACB (ENSG00000076555)
    CSI Score: 4.16
    Ensembl ID: ENSG00000076555
  • 53. Gene Symbol: BTD (ENSG00000169814)
    CSI Score: 4.08
    Ensembl ID: ENSG00000169814
  • 54. Gene Symbol: AMY2B (ENSG00000240038)
    CSI Score: 4.07
    Ensembl ID: ENSG00000240038
  • 55. Gene Symbol: ACO1 (ENSG00000122729)
    CSI Score: 3.98
    Ensembl ID: ENSG00000122729
  • 56. Gene Symbol: ADGRB3 (ENSG00000135298)
    CSI Score: 3.96
    Ensembl ID: ENSG00000135298
  • 57. Gene Symbol: BCKDHB (ENSG00000083123)
    CSI Score: 3.95
    Ensembl ID: ENSG00000083123
  • 58. Gene Symbol: BCL2 (ENSG00000171791)
    CSI Score: 3.94
    Ensembl ID: ENSG00000171791
  • 59. Gene Symbol: ABCA2 (ENSG00000107331)
    CSI Score: 3.93
    Ensembl ID: ENSG00000107331
  • 60. Gene Symbol: BICD1 (ENSG00000151746)
    CSI Score: 3.93
    Ensembl ID: ENSG00000151746
  • 61. Gene Symbol: ATP1A3 (ENSG00000105409)
    CSI Score: 3.9
    Ensembl ID: ENSG00000105409
  • 62. Gene Symbol: STS (ENSG00000101846)
    CSI Score: 3.89
    Ensembl ID: ENSG00000101846
  • 63. Gene Symbol: AQP1 (ENSG00000240583)
    CSI Score: 3.89
    Ensembl ID: ENSG00000240583
  • 64. Gene Symbol: ANK2 (ENSG00000145362)
    CSI Score: 3.88
    Ensembl ID: ENSG00000145362
  • 65. Gene Symbol: DST (ENSG00000151914)
    CSI Score: 3.87
    Ensembl ID: ENSG00000151914
  • 66. Gene Symbol: APLNR (ENSG00000134817)
    CSI Score: 3.84
    Ensembl ID: ENSG00000134817
  • 67. Gene Symbol: ADORA1 (ENSG00000163485)
    CSI Score: 3.83
    Ensembl ID: ENSG00000163485
  • 68. Gene Symbol: C5 (ENSG00000106804)
    CSI Score: 3.82
    Ensembl ID: ENSG00000106804
  • 69. Gene Symbol: BBS4 (ENSG00000140463)
    CSI Score: 3.82
    Ensembl ID: ENSG00000140463
  • 70. Gene Symbol: ABCA1 (ENSG00000165029)
    CSI Score: 3.78
    Ensembl ID: ENSG00000165029
  • 71. Gene Symbol: ACO2 (ENSG00000100412)
    CSI Score: 3.78
    Ensembl ID: ENSG00000100412
  • 72. Gene Symbol: BCL6 (ENSG00000113916)
    CSI Score: 3.74
    Ensembl ID: ENSG00000113916
  • 73. Gene Symbol: ADD3 (ENSG00000148700)
    CSI Score: 3.71
    Ensembl ID: ENSG00000148700
  • 74. Gene Symbol: ADCYAP1R1 (ENSG00000078549)
    CSI Score: 3.7
    Ensembl ID: ENSG00000078549
  • 75. Gene Symbol: ASPA (ENSG00000108381)
    CSI Score: 3.64
    Ensembl ID: ENSG00000108381
  • 76. Gene Symbol: ARL3 (ENSG00000138175)
    CSI Score: 3.59
    Ensembl ID: ENSG00000138175
  • 77. Gene Symbol: ATR (ENSG00000175054)
    CSI Score: 3.56
    Ensembl ID: ENSG00000175054
  • 78. Gene Symbol: ADRA1B (ENSG00000170214)
    CSI Score: 3.52
    Ensembl ID: ENSG00000170214
  • 79. Gene Symbol: ADGRB2 (ENSG00000121753)
    CSI Score: 3.48
    Ensembl ID: ENSG00000121753
  • 80. Gene Symbol: APBB1 (ENSG00000166313)
    CSI Score: 3.45
    Ensembl ID: ENSG00000166313
  • 81. Gene Symbol: GRK3 (ENSG00000100077)
    CSI Score: 3.43
    Ensembl ID: ENSG00000100077
  • 82. Gene Symbol: AR (ENSG00000169083)
    CSI Score: 3.4
    Ensembl ID: ENSG00000169083
  • 83. Gene Symbol: ATP6V1G2 (ENSG00000213760)
    CSI Score: 3.36
    Ensembl ID: ENSG00000213760
  • 84. Gene Symbol: ARHGAP5 (ENSG00000100852)
    CSI Score: 3.34
    Ensembl ID: ENSG00000100852
  • 85. Gene Symbol: ADCY9 (ENSG00000162104)
    CSI Score: 3.32
    Ensembl ID: ENSG00000162104
  • 86. Gene Symbol: ATP6V1A (ENSG00000114573)
    CSI Score: 3.32
    Ensembl ID: ENSG00000114573
  • 87. Gene Symbol: ACYP2 (ENSG00000170634)
    CSI Score: 3.28
    Ensembl ID: ENSG00000170634
  • 88. Gene Symbol: ABL2 (ENSG00000143322)
    CSI Score: 3.27
    Ensembl ID: ENSG00000143322
  • 89. Gene Symbol: ACADSB (ENSG00000196177)
    CSI Score: 3.26
    Ensembl ID: ENSG00000196177
  • 90. Gene Symbol: BBS1 (ENSG00000174483)
    CSI Score: 3.26
    Ensembl ID: ENSG00000174483
  • 91. Gene Symbol: RERE (ENSG00000142599)
    CSI Score: 3.16
    Ensembl ID: ENSG00000142599
  • 92. Gene Symbol: ADCY1 (ENSG00000164742)
    CSI Score: 3.13
    Ensembl ID: ENSG00000164742
  • 93. Gene Symbol: ABL1 (ENSG00000097007)
    CSI Score: 3.1
    Ensembl ID: ENSG00000097007
  • 94. Gene Symbol: ALDH2 (ENSG00000111275)
    CSI Score: 3.08
    Ensembl ID: ENSG00000111275
  • 95. Gene Symbol: ACVR2A (ENSG00000121989)
    CSI Score: 3.07
    Ensembl ID: ENSG00000121989
  • 96. Gene Symbol: AUH (ENSG00000148090)
    CSI Score: 3.06
    Ensembl ID: ENSG00000148090
  • 97. Gene Symbol: BMAL1 (ENSG00000133794)
    CSI Score: 3.06
    Ensembl ID: ENSG00000133794
  • 98. Gene Symbol: C1S (ENSG00000182326)
    CSI Score: 3.04
    Ensembl ID: ENSG00000182326
  • 99. Gene Symbol: ADK (ENSG00000156110)
    CSI Score: 3.04
    Ensembl ID: ENSG00000156110
  • 100. Gene Symbol: BRAF (ENSG00000157764)
    CSI Score: 3.01
    Ensembl ID: ENSG00000157764
  • 101. Gene Symbol: ASCL1 (ENSG00000139352)
    CSI Score: 2.99
    Ensembl ID: ENSG00000139352
  • 102. Gene Symbol: ADCY3 (ENSG00000138031)
    CSI Score: 2.98
    Ensembl ID: ENSG00000138031
  • 103. Gene Symbol: BCAT2 (ENSG00000105552)
    CSI Score: 2.94
    Ensembl ID: ENSG00000105552
  • 104. Gene Symbol: ARNT (ENSG00000143437)
    CSI Score: 2.92
    Ensembl ID: ENSG00000143437
  • 105. Gene Symbol: SHROOM2 (ENSG00000146950)
    CSI Score: 2.9
    Ensembl ID: ENSG00000146950
  • 106. Gene Symbol: ADARB1 (ENSG00000197381)
    CSI Score: 2.83
    Ensembl ID: ENSG00000197381
  • 107. Gene Symbol: ADRB1 (ENSG00000043591)
    CSI Score: 2.8
    Ensembl ID: ENSG00000043591
  • 108. Gene Symbol: ABCB7 (ENSG00000131269)
    CSI Score: 2.78
    Ensembl ID: ENSG00000131269
  • 109. Gene Symbol: ATP2A1 (ENSG00000196296)
    CSI Score: 2.75
    Ensembl ID: ENSG00000196296
  • 110. Gene Symbol: RHOB (ENSG00000143878)
    CSI Score: 2.74
    Ensembl ID: ENSG00000143878
  • 111. Gene Symbol: ADD1 (ENSG00000087274)
    CSI Score: 2.73
    Ensembl ID: ENSG00000087274
  • 112. Gene Symbol: ATP7B (ENSG00000123191)
    CSI Score: 2.69
    Ensembl ID: ENSG00000123191
  • 113. Gene Symbol: ACVR1 (ENSG00000115170)
    CSI Score: 2.67
    Ensembl ID: ENSG00000115170
  • 114. Gene Symbol: AQP6 (ENSG00000086159)
    CSI Score: 2.65
    Ensembl ID: ENSG00000086159
  • 115. Gene Symbol: ACADVL (ENSG00000072778)
    CSI Score: 2.63
    Ensembl ID: ENSG00000072778
  • 116. Gene Symbol: ATM (ENSG00000149311)
    CSI Score: 2.62
    Ensembl ID: ENSG00000149311
  • 117. Gene Symbol: AK1 (ENSG00000106992)
    CSI Score: 2.62
    Ensembl ID: ENSG00000106992
  • 118. Gene Symbol: BDH1 (ENSG00000161267)
    CSI Score: 2.59
    Ensembl ID: ENSG00000161267
  • 119. Gene Symbol: ATP6V1C1 (ENSG00000155097)
    CSI Score: 2.56
    Ensembl ID: ENSG00000155097
  • 120. Gene Symbol: BARD1 (ENSG00000138376)
    CSI Score: 2.55
    Ensembl ID: ENSG00000138376
  • 121. Gene Symbol: ADCY5 (ENSG00000173175)
    CSI Score: 2.54
    Ensembl ID: ENSG00000173175
  • 122. Gene Symbol: ANXA4 (ENSG00000196975)
    CSI Score: 2.49
    Ensembl ID: ENSG00000196975
  • 123. Gene Symbol: ARSD (ENSG00000006756)
    CSI Score: 2.46
    Ensembl ID: ENSG00000006756
  • 124. Gene Symbol: ATP2A2 (ENSG00000174437)
    CSI Score: 2.44
    Ensembl ID: ENSG00000174437
  • 125. Gene Symbol: ARHGAP6 (ENSG00000047648)
    CSI Score: 2.39
    Ensembl ID: ENSG00000047648
  • 126. Gene Symbol: AP1B1 (ENSG00000100280)
    CSI Score: 2.38
    Ensembl ID: ENSG00000100280
  • 127. Gene Symbol: ARSF (ENSG00000062096)
    CSI Score: 2.37
    Ensembl ID: ENSG00000062096
  • 128. Gene Symbol: ATP1A4 (ENSG00000132681)
    CSI Score: 2.3
    Ensembl ID: ENSG00000132681
  • 129. Gene Symbol: ARHGDIG (ENSG00000242173)
    CSI Score: 2.3
    Ensembl ID: ENSG00000242173
  • 130. Gene Symbol: ALAD (ENSG00000148218)
    CSI Score: 2.29
    Ensembl ID: ENSG00000148218
  • 131. Gene Symbol: BRCA1 (ENSG00000012048)
    CSI Score: 2.28
    Ensembl ID: ENSG00000012048
  • 132. Gene Symbol: ADCY6 (ENSG00000174233)
    CSI Score: 2.26
    Ensembl ID: ENSG00000174233
  • 133. Gene Symbol: ADAM10 (ENSG00000137845)
    CSI Score: 2.24
    Ensembl ID: ENSG00000137845
  • 134. Gene Symbol: ADD2 (ENSG00000075340)
    CSI Score: 2.21
    Ensembl ID: ENSG00000075340
  • 135. Gene Symbol: TRIM23 (ENSG00000113595)
    CSI Score: 2.2
    Ensembl ID: ENSG00000113595
  • 136. Gene Symbol: AMPD3 (ENSG00000133805)
    CSI Score: 2.19
    Ensembl ID: ENSG00000133805
  • 137. Gene Symbol: BMP1 (ENSG00000168487)
    CSI Score: 2.1
    Ensembl ID: ENSG00000168487
  • 138. Gene Symbol: APP (ENSG00000142192)
    CSI Score: 2.07
    Ensembl ID: ENSG00000142192
  • 139. Gene Symbol: ACY1 (ENSG00000243989)
    CSI Score: 2.07
    Ensembl ID: ENSG00000243989
  • 140. Gene Symbol: ACOX1 (ENSG00000161533)
    CSI Score: 2.06
    Ensembl ID: ENSG00000161533
  • 141. Gene Symbol: BCL2L2 (ENSG00000129473)
    CSI Score: 2.06
    Ensembl ID: ENSG00000129473
  • 142. Gene Symbol: ARHGAP1 (ENSG00000175220)
    CSI Score: 1.99
    Ensembl ID: ENSG00000175220
  • 143. Gene Symbol: AMT (ENSG00000145020)
    CSI Score: 1.98
    Ensembl ID: ENSG00000145020
  • 144. Gene Symbol: ATP2B1 (ENSG00000070961)
    CSI Score: 1.98
    Ensembl ID: ENSG00000070961
  • 145. Gene Symbol: AARS1 (ENSG00000090861)
    CSI Score: 1.93
    Ensembl ID: ENSG00000090861
  • 146. Gene Symbol: AMFR (ENSG00000159461)
    CSI Score: 1.92
    Ensembl ID: ENSG00000159461
  • 147. Gene Symbol: BNIP3 (ENSG00000176171)
    CSI Score: 1.9
    Ensembl ID: ENSG00000176171
  • 148. Gene Symbol: BCL7A (ENSG00000110987)
    CSI Score: 1.89
    Ensembl ID: ENSG00000110987
  • 149. Gene Symbol: APOC1 (ENSG00000130208)
    CSI Score: 1.88
    Ensembl ID: ENSG00000130208
  • 150. Gene Symbol: AP2A2 (ENSG00000183020)
    CSI Score: 1.86
    Ensembl ID: ENSG00000183020
  • 151. Gene Symbol: ATP6V0C (ENSG00000185883)
    CSI Score: 1.85
    Ensembl ID: ENSG00000185883
  • 152. Gene Symbol: ATP1B1 (ENSG00000143153)
    CSI Score: 1.81
    Ensembl ID: ENSG00000143153
  • 153. Gene Symbol: ZFP36L1 (ENSG00000185650)
    CSI Score: 1.81
    Ensembl ID: ENSG00000185650
  • 154. Gene Symbol: ACYP1 (ENSG00000119640)
    CSI Score: 1.76
    Ensembl ID: ENSG00000119640
  • 155. Gene Symbol: ANGPT2 (ENSG00000091879)
    CSI Score: 1.76
    Ensembl ID: ENSG00000091879
  • 156. Gene Symbol: CAPN5 (ENSG00000149260)
    CSI Score: 1.74
    Ensembl ID: ENSG00000149260
  • 157. Gene Symbol: APOC2 (ENSG00000234906)
    CSI Score: 1.73
    Ensembl ID: ENSG00000234906
  • 158. Gene Symbol: HCN2 (ENSG00000099822)
    CSI Score: 1.73
    Ensembl ID: ENSG00000099822
  • 159. Gene Symbol: BPHL (ENSG00000137274)
    CSI Score: 1.73
    Ensembl ID: ENSG00000137274
  • 160. Gene Symbol: ACADM (ENSG00000117054)
    CSI Score: 1.69
    Ensembl ID: ENSG00000117054
  • 161. Gene Symbol: BHMT (ENSG00000145692)
    CSI Score: 1.64
    Ensembl ID: ENSG00000145692
  • 162. Gene Symbol: ASNS (ENSG00000070669)
    CSI Score: 1.64
    Ensembl ID: ENSG00000070669
  • 163. Gene Symbol: ATP2B3 (ENSG00000067842)
    CSI Score: 1.63
    Ensembl ID: ENSG00000067842
  • 164. Gene Symbol: BLMH (ENSG00000108578)
    CSI Score: 1.62
    Ensembl ID: ENSG00000108578
  • 165. Gene Symbol: ACVR2B (ENSG00000114739)
    CSI Score: 1.61
    Ensembl ID: ENSG00000114739
  • 166. Gene Symbol: FAS (ENSG00000026103)
    CSI Score: 1.61
    Ensembl ID: ENSG00000026103
  • 167. Gene Symbol: BNIP3L (ENSG00000104765)
    CSI Score: 1.61
    Ensembl ID: ENSG00000104765
  • 168. Gene Symbol: XIAP (ENSG00000101966)
    CSI Score: 1.59
    Ensembl ID: ENSG00000101966
  • 169. Gene Symbol: BCL2L1 (ENSG00000171552)
    CSI Score: 1.59
    Ensembl ID: ENSG00000171552
  • 170. Gene Symbol: KLF9 (ENSG00000119138)
    CSI Score: 1.59
    Ensembl ID: ENSG00000119138
  • 171. Gene Symbol: ATRX (ENSG00000085224)
    CSI Score: 1.58
    Ensembl ID: ENSG00000085224
  • 172. Gene Symbol: AP2B1 (ENSG00000006125)
    CSI Score: 1.58
    Ensembl ID: ENSG00000006125
  • 173. Gene Symbol: AKT2 (ENSG00000105221)
    CSI Score: 1.55
    Ensembl ID: ENSG00000105221
  • 174. Gene Symbol: ARSL (ENSG00000157399)
    CSI Score: 1.55
    Ensembl ID: ENSG00000157399
  • 175. Gene Symbol: ANK3 (ENSG00000151150)
    CSI Score: 1.54
    Ensembl ID: ENSG00000151150
  • 176. Gene Symbol: SLC25A4 (ENSG00000151729)
    CSI Score: 1.52
    Ensembl ID: ENSG00000151729
  • 177. Gene Symbol: ADM (ENSG00000148926)
    CSI Score: 1.51
    Ensembl ID: ENSG00000148926
  • 178. Gene Symbol: ATF1 (ENSG00000123268)
    CSI Score: 1.51
    Ensembl ID: ENSG00000123268
  • 179. Gene Symbol: AMPD2 (ENSG00000116337)
    CSI Score: 1.49
    Ensembl ID: ENSG00000116337
  • 180. Gene Symbol: SERPINA3 (ENSG00000196136)
    CSI Score: 1.47
    Ensembl ID: ENSG00000196136
  • 181. Gene Symbol: AP1G1 (ENSG00000166747)
    CSI Score: 1.47
    Ensembl ID: ENSG00000166747
  • 182. Gene Symbol: BSG (ENSG00000172270)
    CSI Score: 1.46
    Ensembl ID: ENSG00000172270
  • 183. Gene Symbol: C1R (ENSG00000159403)
    CSI Score: 1.45
    Ensembl ID: ENSG00000159403
  • 184. Gene Symbol: ACAT1 (ENSG00000075239)
    CSI Score: 1.4
    Ensembl ID: ENSG00000075239
  • 185. Gene Symbol: ARG2 (ENSG00000081181)
    CSI Score: 1.38
    Ensembl ID: ENSG00000081181
  • 186. Gene Symbol: ART3 (ENSG00000156219)
    CSI Score: 1.38
    Ensembl ID: ENSG00000156219
  • 187. Gene Symbol: AP2A1 (ENSG00000196961)
    CSI Score: 1.36
    Ensembl ID: ENSG00000196961
  • 188. Gene Symbol: ADORA3 (ENSG00000282608)
    CSI Score: 1.3
    Ensembl ID: ENSG00000282608
  • 189. Gene Symbol: ATP6V1B2 (ENSG00000147416)
    CSI Score: 1.29
    Ensembl ID: ENSG00000147416
  • 190. Gene Symbol: ACAA1 (ENSG00000060971)
    CSI Score: 1.29
    Ensembl ID: ENSG00000060971
  • 191. Gene Symbol: ACVR1B (ENSG00000135503)
    CSI Score: 1.27
    Ensembl ID: ENSG00000135503
  • 192. Gene Symbol: ASIP (ENSG00000101440)
    CSI Score: 1.25
    Ensembl ID: ENSG00000101440
  • 193. Gene Symbol: ALDH3A2 (ENSG00000072210)
    CSI Score: 1.24
    Ensembl ID: ENSG00000072210
  • 194. Gene Symbol: BACH1 (ENSG00000156273)
    CSI Score: 1.23
    Ensembl ID: ENSG00000156273
  • 195. Gene Symbol: PARP4 (ENSG00000102699)
    CSI Score: 1.2
    Ensembl ID: ENSG00000102699
  • 196. Gene Symbol: AMH (ENSG00000104899)
    CSI Score: 1.17
    Ensembl ID: ENSG00000104899
  • 197. Gene Symbol: ACADL (ENSG00000115361)
    CSI Score: 1.16
    Ensembl ID: ENSG00000115361
  • 198. Gene Symbol: ZFP36L2 (ENSG00000152518)
    CSI Score: 1.14
    Ensembl ID: ENSG00000152518
  • 199. Gene Symbol: ATP5F1C (ENSG00000165629)
    CSI Score: 1.12
    Ensembl ID: ENSG00000165629
  • 200. Gene Symbol: ACADS (ENSG00000122971)
    CSI Score: 1.09
    Ensembl ID: ENSG00000122971

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
CSI Score: A combined effect size and statistical significance measure for astrocyte. Higher scores indicate a stronger, more significant difference in expression.
(Previously described as "Fold Change", but now represents Cliff's Delta × –log10(p).)

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
CSI Score: A combined effect size and statistical significance measure for astrocyte. Higher scores indicate a stronger, more significant difference in expression.
Average CSI: csi sum / gene count
**Key Characteristics** 1. **Shape and Structure**: Astrocytes are irregularly shaped with many long processes, including those with 'end feet' that form the glial (limiting) membrane. 2. **Functions**: Astrocytes regulate the extracellular ionic and chemical environment, contribute to the blood-brain barrier, and respond to injury. 3. **Metabolic Processes**: Astrocytes are involved in glucose metabolism, amino acid transport, and ion transport. 4. **Iron Homeostasis**: Astrocytes play a crucial role in iron homeostasis, regulating iron uptake and transport. 5. **Immune Responses**: Astrocytes are involved in immune responses, including the production of cytokines and the regulation of immune cells. 6. **Cell Signaling**: Astrocytes are responsive to various signaling pathways, including those involved in inflammation, apoptosis, and autophagy. **Clinical Significance** 1. **Neurological Disorders**: Astrocytes are involved in various neurological disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and stroke. 2. **Traumatic Brain Injury**: Astrocytes respond to injury, and their dysfunction can contribute to the development of secondary injury. 3. **Infectious Diseases**: Astrocytes play a role in the immune response to infections, including those caused by viruses and bacteria. 4. **Cancer**: Astrocytes can contribute to cancer development and progression, particularly in the context of glioblastoma. 5. **Neurodegenerative Diseases**: Astrocytes are involved in the pathogenesis of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Huntington's disease. **Genetic and Molecular Aspects** 1. **Gene Symbol**: HBG2 (Ensembl ID: ENSG00000196565) 2. **Pathways/Ontology**: Blood microparticle, Carbon dioxide transport, Cellular oxidant detoxification, Cytosol, Factors involved in megakaryocyte development and platelet production, Haptoglobin-hemoglobin complex, Haptoglobin binding, Heme binding, Hemoglobin alpha binding, Hemoglobin complex, Hemostasis, Hydrogen peroxide catabolic process, Metal ion binding, Organic acid binding, Oxygen binding, Oxygen carrier activity, Oxygen transport, Peroxidase activity, Protein binding 3. **Gene Symbol**: GPC5 (Ensembl ID: ENSG00000179399) 4. **Pathways/Ontology**: A tetrasaccharide linker sequence is required for gag synthesis, Attachment and entry, Cell migration, Cell surface, Chondroitin sulfate/dermatan sulfate metabolism, Collagen-containing extracellular matrix, Defective b3galt6 causes edsp2 and semdjl1, Defective b3gat3 causes jdssdhd, Defective b4galt7 causes eds, progeroid type, Defective ext1 causes exostoses 1, trps2 and chds, Defective ext2 causes exostoses 2, Disease, Diseases associated with glycosaminoglycan metabolism, Diseases of glycosylation, Diseases of metabolism, Early sars-cov-2 infection events, Extracellular region, Glycosaminoglycan metabolism, Golgi lumen, Hedgehog ligand biogenesis, Heparan sulfate/heparin (hs-gag) metabolism, Hs-gag biosynthesis, Hs-gag degradation, Infectious disease, Lysosomal lumen, Membrane, Metabolism, Metabolism of carbohydrates, Metabolism of fat-soluble vitamins, Metabolism of vitamins and cofactors, Plasma membrane, Positive regulation of canonical wnt signaling pathway, Protein binding, Regulation of protein localization to membrane, Release of hh-np from the secreting cell, Respiratory syncytial virus (rsv) attachment and entry, Respiratory syncytial virus infection pathway, Retinoid metabolism and transport, Rsv-host interactions, Sars-cov-2 infection, Sars-cov infections, Sensory perception, Side of membrane, Signaling by hedgehog, Signal transduction, Viral infection pathways, Visual phototransduction 5. **Gene Symbol**: FTH1 (Ensembl ID: ENSG00000167996) 6. **Pathways/Ontology**: Autolysosome, Binding and uptake of ligands by scavenger receptors, Cytoplasm, Cytosol, Extracellular exosome, Extracellular region, Ferric iron binding, Ferrous iron binding, Ferroxidase activity, Ficolin-1-rich granule lumen, Golgi associated vesicle biogenesis, Identical protein binding, Immune response, Immune system, Innate immune system, Intracellular ferritin complex, Intracellular iron ion homeostasis, Intracellular sequestering of iron ion, Iron ion binding, Iron ion sequestering activity, Iron ion transport, Iron uptake and transport, Membrane trafficking, Negative regulation of cell population proliferation, Negative regulation of fibroblast proliferation, Neutrophil degranulation, Nucleus, Protein binding, Scavenging by class a receptors, Tertiary granule lumen, Trans-golgi network vesicle budding, Transport of small molecules, Vesicle-mediated transport 7. **Gene Symbol**: HMGB1 (Ensembl ID: ENSG00000189403) 8. **Pathways/Ontology**: Activation of innate immune response, Adaptive immune system, Advanced glycosylation endproduct receptor signaling, Alphav-beta3 integrin-hmgb1 complex, Antigen processing-cross presentation, Apoptosis, Apoptosis induced dna fragmentation, Apoptotic cell clearance, Apoptotic execution phase, Autophagy, Bubble dna binding, C-x-c chemokine binding, Cell surface, Cellular response to lipopolysaccharide, Chemoattractant activity, Class i mhc mediated antigen processing & presentation, Condensed chromosome, Cytokine activity, Cytokine signaling in immune system, Damaged dna binding, Ddx58/ifih1-mediated induction of interferon-alpha/beta, Dendritic cell chemotaxis, Disease, Diseases associated with the tlr signaling cascade, Diseases of immune system, Dna-binding transcription factor binding, Dna binding, bending, Dna geometric change, Dna polymerase binding, Dna recombination, Dna topological change, Double-strand break repair via nonhomologous end joining, Double-stranded dna binding, Endoplasmic reticulum, Endoplasmic reticulum-golgi intermediate compartment, Endosome, Er-phagosome pathway, Extracellular region, Extracellular space, Ficolin-1-rich granule lumen, Four-way junction dna binding, Heterochromatin formation, Immune system, Inflammatory response, Inflammatory response to antigenic stimulus, Innate immune response, Innate immune system, Integrin binding, Interleukin-1 family signaling, Interleukin-1 signaling, Irak4 deficiency (tlr2/4), Lipopolysaccharide binding, Lyase activity, Myd88 cascade initiated on plasma membrane, Myd88 deficiency (tlr2/4), Myd88 dependent cascade initiated on endosome, Myd88-independent tlr4 cascade, Myd88:mal(tirap) cascade initiated on plasma membrane, Myeloid dendritic cell activation, Negative regulation of apoptotic cell clearance, Negative regulation of blood vessel endothelial cell migration, Negative regulation of cd4-positive, alpha-beta t cell differentiation, Negative regulation of rna polymerase ii transcription preinitiation complex assembly, Negative regulation of transcription by rna polymerase ii, Negative regulation of type ii interferon production, Neuron projection development, Neutrophil clearance, Neutrophil degranulation, Nucleoplasm, Nucleus, Phosphatidylserine binding, Positive chemotaxis, Positive regulation of activated t cell proliferation, Positive regulation of apoptotic process, Positive regulation of autophagy, Positive regulation of blood vessel endothelial cell migration, Positive regulation of chemokine (c-x-c motif) ligand 2 production, Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, Positive regulation of cytosolic calcium ion concentration, Positive regulation of dendritic cell differentiation, Positive regulation of dna binding, Positive regulation of dna ligation, Positive regulation of erk1 and erk2 cascade, Positive regulation of interleukin-1 production, Positive regulation of interleukin-6 production, Positive regulation of interleukin-8 production, Positive regulation of interleukin-10 production, Positive regulation of interleukin-12 production, Positive regulation of jnk cascade, Positive regulation of mapk cascade, Positive regulation of mismatch repair, Positive regulation of monocyte chemotaxis, Positive regulation of toll-like receptor 9 signaling pathway, Positive regulation of transcription by rna polymerase ii, Positive regulation of tumor necrosis factor production, Positive regulation of vascular endothelial cell proliferation, Positive regulation of viral entry into host cell, Programmed cell death, Protein binding, Pyroptosis, Rage receptor binding, Receptor lig