Details for: TRPS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 465.9095
Cell Significance Index: -72.4700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 277.1214
Cell Significance Index: -70.2900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 153.4347
Cell Significance Index: -72.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 142.6929
Cell Significance Index: -57.9700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 134.1796
Cell Significance Index: -69.0200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 60.8803
Cell Significance Index: -58.1300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 58.7856
Cell Significance Index: -72.4800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 29.6584
Cell Significance Index: -64.9100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 22.0677
Cell Significance Index: -67.7800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 18.4159
Cell Significance Index: -72.6700 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 9.0337
Cell Significance Index: 55.6000 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 7.0290
Cell Significance Index: 98.2900 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 6.4945
Cell Significance Index: 57.6500 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 5.8431
Cell Significance Index: 36.0500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 4.2740
Cell Significance Index: 119.4500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 3.3756
Cell Significance Index: 158.6500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.5562
Cell Significance Index: 113.0700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.3956
Cell Significance Index: 134.4300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.2634
Cell Significance Index: 85.7100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.9303
Cell Significance Index: 1335.0600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.8800
Cell Significance Index: 377.1200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.4900
Cell Significance Index: 42.5200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.1819
Cell Significance Index: 30.3800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.0193
Cell Significance Index: 450.6500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9499
Cell Significance Index: 340.7200 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.9088
Cell Significance Index: 13.0500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.6921
Cell Significance Index: 439.5500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6162
Cell Significance Index: 117.2700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.6083
Cell Significance Index: 8.3000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.5461
Cell Significance Index: 247.8400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5423
Cell Significance Index: 41.6200 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.4729
Cell Significance Index: 5.9600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3292
Cell Significance Index: 297.2500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2463
Cell Significance Index: 18.3600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1818
Cell Significance Index: 342.3600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1630
Cell Significance Index: 10.0200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1352
Cell Significance Index: 9.5600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1093
Cell Significance Index: 201.6000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0920
Cell Significance Index: 141.6300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0808
Cell Significance Index: 11.1000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0750
Cell Significance Index: 40.9500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0348
Cell Significance Index: 6.9000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0185
Cell Significance Index: 1.8400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0013
Cell Significance Index: -0.0600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0330
Cell Significance Index: -44.8400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0464
Cell Significance Index: -5.7000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0486
Cell Significance Index: -8.7700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0639
Cell Significance Index: -46.8400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0696
Cell Significance Index: -9.0000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0750
Cell Significance Index: -12.2100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0892
Cell Significance Index: -66.0800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1033
Cell Significance Index: -78.2000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1064
Cell Significance Index: -3.7400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1345
Cell Significance Index: -84.0200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1374
Cell Significance Index: -77.5000 - Cell Name: chandelier cell (CL4023083)
Fold Change: -0.1505
Cell Significance Index: -1.2200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1535
Cell Significance Index: -3.0000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1690
Cell Significance Index: -3.7000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1940
Cell Significance Index: -6.2200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2032
Cell Significance Index: -12.4600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2035
Cell Significance Index: -29.5800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2074
Cell Significance Index: -59.6800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2329
Cell Significance Index: -27.1400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2463
Cell Significance Index: -16.5600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.3125
Cell Significance Index: -33.9900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.3771
Cell Significance Index: -48.3400 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3848
Cell Significance Index: -8.2300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3898
Cell Significance Index: -11.2300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3934
Cell Significance Index: -40.1900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.3971
Cell Significance Index: -18.0000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.4016
Cell Significance Index: -84.5900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4042
Cell Significance Index: -42.0900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.4162
Cell Significance Index: -71.0700 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.4546
Cell Significance Index: -7.8600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5305
Cell Significance Index: -13.2600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.5308
Cell Significance Index: -62.6000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.6372
Cell Significance Index: -41.1100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.6939
Cell Significance Index: -79.5000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7037
Cell Significance Index: -44.3500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.7515
Cell Significance Index: -51.9700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7816
Cell Significance Index: -61.9000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.8390
Cell Significance Index: -50.3700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.8737
Cell Significance Index: -14.6200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.8961
Cell Significance Index: -46.6800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.9682
Cell Significance Index: -23.2200 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.9862
Cell Significance Index: -12.7000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.0253
Cell Significance Index: -21.7600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.0255
Cell Significance Index: -53.2700 - Cell Name: astrocyte (CL0000127)
Fold Change: -1.0817
Cell Significance Index: -12.3800 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -1.1746
Cell Significance Index: -17.8700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -1.2218
Cell Significance Index: -29.8100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.3219
Cell Significance Index: -43.2800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.3430
Cell Significance Index: -70.5200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.3534
Cell Significance Index: -36.2700 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -1.3827
Cell Significance Index: -21.0000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.4484
Cell Significance Index: -31.3800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.5175
Cell Significance Index: -48.3300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -1.5431
Cell Significance Index: -32.2100 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.6037
Cell Significance Index: -56.1800 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -1.6312
Cell Significance Index: -12.4700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1304941636
Symbol: TRPS1_HUMAN
Name: Zinc finger transcription factor Trps1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10615131
Title: Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I.
PubMed ID: 10615131
DOI: 10.1038/71717
PubMed ID: 10974077
Title: Characterization of a zinc-finger protein and its association with apoptosis in prostate cancer cells.
PubMed ID: 10974077
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12885770
Title: The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.
PubMed ID: 12885770
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17391059
Title: SUMOylation modulates transcriptional repression by TRPS1.
PubMed ID: 17391059
DOI: 10.1515/bc.2007.051
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19389374
Title: Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.
PubMed ID: 19389374
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 11112658
Title: Genotypic and phenotypic spectrum in tricho-rhino-phalangeal syndrome types I and III.
PubMed ID: 11112658
DOI: 10.1086/316926
PubMed ID: 11807863
Title: Missense mutation of TRPS1 in a family of tricho-rhino-phalangeal syndrome type III.
PubMed ID: 11807863
DOI: 10.1002/ajmg.10081
PubMed ID: 14560312
Title: Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal.
PubMed ID: 14560312
Sequence Information:
- Length: 1281
- Mass: 141521
- Checksum: 2157B04F5BEB71CC
- Sequence:
MVRKKNPPLR NVASEGEGQI LEPIGTESKV SGKNKEFSAD QMSENTDQSD AAELNHKEEH SLHVQDPSSS SKKDLKSAVL SEKAGFNYES PSKGGNFPSF PHDEVTDRNM LAFSSPAAGG VCEPLKSPQR AEADDPQDMA CTPSGDSLET KEDQKMSPKA TEETGQAQSG QANCQGLSPV SVASKNPQVP SDGGVRLNKS KTDLLVNDNP DPAPLSPELQ DFKCNICGYG YYGNDPTDLI KHFRKYHLGL HNRTRQDAEL DSKILALHNM VQFSHSKDFQ KVNRSVFSGV LQDINSSRPV LLNGTYDVQV TSGGTFIGIG RKTPDCQGNT KYFRCKFCNF TYMGNSSTEL EQHFLQTHPN KIKASLPSSE VAKPSEKNSN KSIPALQSSD SGDLGKWQDK ITVKAGDDTP VGYSVPIKPL DSSRQNGTEA TSYYWCKFCS FSCESSSSLK LLEHYGKQHG AVQSGGLNPE LNDKLSRGSV INQNDLAKSS EGETMTKTDK SSSGAKKKDF SSKGAEDNMV TSYNCQFCDF RYSKSHGPDV IVVGPLLRHY QQLHNIHKCT IKHCPFCPRG LCSPEKHLGE ITYPFACRKS NCSHCALLLL HLSPGAAGSS RVKHQCHQCS FTTPDVDVLL FHYESVHESQ ASDVKQEANH LQGSDGQQSV KESKEHSCTK CDFITQVEEE ISRHYRRAHS CYKCRQCSFT AADTQSLLEH FNTVHCQEQD ITTANGEEDG HAISTIKEEP KIDFRVYNLL TPDSKMGEPV SESVVKREKL EEKDGLKEKV WTESSSDDLR NVTWRGADIL RGSPSYTQAS LGLLTPVSGT QEQTKTLRDS PNVEAAHLAR PIYGLAVETK GFLQGAPAGG EKSGALPQQY PASGENKSKD ESQSLLRRRR GSGVFCANCL TTKTSLWRKN ANGGYVCNAC GLYQKLHSTP RPLNIIKQNN GEQIIRRRTR KRLNPEALQA EQLNKQQRGS NEEQVNGSPL ERRSEDHLTE SHQREIPLPS LSKYEAQGSL TKSHSAQQPV LVSQTLDIHK RMQPLHIQIK SPQESTGDPG NSSSVSEGKG SSERGSPIEK YMRPAKHPNY SPPGSPIEKY QYPLFGLPFV HNDFQSEADW LRFWSKYKLS VPGNPHYLSH VPGLPNPCQN YVPYPTFNLP PHFSAVGSDN DIPLDLAIKH SRPGPTANGA SKEKTKAPPN VKNEGPLNVV KTEKVDRSTQ DELSTKCVHC GIVFLDEVMY ALHMSCHGDS GPFQCSICQH LCTDKYDFTT HIQRGLHRNN AQVEKNGKPK E
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.