Details for: DLG2

Gene ID: 1740

Symbol: DLG2

Ensembl ID: ENSG00000150672

Description: discs large MAGUK scaffold protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 1094.9870
    Cell Significance Index: -170.3200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 673.4258
    Cell Significance Index: -170.8100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 138.1396
    Cell Significance Index: -170.3200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 57.8032
    Cell Significance Index: -177.5400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 43.5623
    Cell Significance Index: -95.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 18.3731
    Cell Significance Index: 11668.8200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 9.8959
    Cell Significance Index: 237.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 9.4451
    Cell Significance Index: 635.0900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 8.4792
    Cell Significance Index: 521.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 8.1228
    Cell Significance Index: 231.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 7.4918
    Cell Significance Index: 2687.1800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 6.9641
    Cell Significance Index: 308.0400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 6.8688
    Cell Significance Index: 527.1000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 6.7739
    Cell Significance Index: 256.5100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 5.6676
    Cell Significance Index: 3919.9300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 4.2810
    Cell Significance Index: 858.7600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.8995
    Cell Significance Index: 7342.2700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.9692
    Cell Significance Index: 57.9500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.7651
    Cell Significance Index: 5099.4600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.1340
    Cell Significance Index: 3285.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.7285
    Cell Significance Index: 44.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.7009
    Cell Significance Index: 771.9900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 1.5676
    Cell Significance Index: 20.3300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.4962
    Cell Significance Index: 25.6400
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 1.3230
    Cell Significance Index: 18.5000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.1319
    Cell Significance Index: 24.2000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.6613
    Cell Significance Index: 10.0600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5423
    Cell Significance Index: 30.4300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5336
    Cell Significance Index: 105.8900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.4783
    Cell Significance Index: 11.6700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.4395
    Cell Significance Index: 597.6100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1957
    Cell Significance Index: 176.7200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.1487
    Cell Significance Index: 1.6200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0833
    Cell Significance Index: 8.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0151
    Cell Significance Index: 2.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0233
    Cell Significance Index: -3.3900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1884
    Cell Significance Index: -138.1000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1946
    Cell Significance Index: -4.2600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2142
    Cell Significance Index: -38.6200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.2228
    Cell Significance Index: -165.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.2428
    Cell Significance Index: -183.7700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2975
    Cell Significance Index: -185.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2986
    Cell Significance Index: -168.4000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.3017
    Cell Significance Index: -164.7400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.3429
    Cell Significance Index: -151.6200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.4595
    Cell Significance Index: -6.1300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4942
    Cell Significance Index: -142.2000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5656
    Cell Significance Index: -69.5400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.5715
    Cell Significance Index: -92.9500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6237
    Cell Significance Index: -17.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.6602
    Cell Significance Index: -23.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.8457
    Cell Significance Index: -83.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.8719
    Cell Significance Index: -183.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.8784
    Cell Significance Index: -150.0000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.9328
    Cell Significance Index: -7.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.9866
    Cell Significance Index: -51.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -1.0753
    Cell Significance Index: -116.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0765
    Cell Significance Index: -66.0000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.0863
    Cell Significance Index: -7.3600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -1.0910
    Cell Significance Index: -149.8300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -1.1242
    Cell Significance Index: -144.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -1.1882
    Cell Significance Index: -153.5100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.1900
    Cell Significance Index: -121.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -1.2579
    Cell Significance Index: -148.3400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.2590
    Cell Significance Index: -146.7200
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -1.3299
    Cell Significance Index: -16.1200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.3917
    Cell Significance Index: -19.9300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.4099
    Cell Significance Index: -20.8200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.5490
    Cell Significance Index: -177.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.5587
    Cell Significance Index: -70.6500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -1.5863
    Cell Significance Index: -22.7800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.5968
    Cell Significance Index: -100.6400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.7430
    Cell Significance Index: -22.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.7636
    Cell Significance Index: -139.6800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.8012
    Cell Significance Index: -22.4600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.9137
    Cell Significance Index: -37.8400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.9195
    Cell Significance Index: -132.7400
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.9719
    Cell Significance Index: -23.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -2.0499
    Cell Significance Index: -152.7800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -2.0537
    Cell Significance Index: -22.0200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -2.2274
    Cell Significance Index: -133.7200
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -2.2319
    Cell Significance Index: -28.6200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -2.3137
    Cell Significance Index: -149.2700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -2.3311
    Cell Significance Index: -76.3200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -2.3315
    Cell Significance Index: -121.4500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -2.3690
    Cell Significance Index: -68.2600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -2.5029
    Cell Significance Index: -108.8300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -2.5211
    Cell Significance Index: -178.3000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.6563
    Cell Significance Index: -124.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -2.6729
    Cell Significance Index: -85.6100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -2.7414
    Cell Significance Index: -87.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -2.7817
    Cell Significance Index: -69.5400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -2.8063
    Cell Significance Index: -56.3400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.8081
    Cell Significance Index: -59.6000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -2.8966
    Cell Significance Index: -27.5600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.8976
    Cell Significance Index: -150.5200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -3.0480
    Cell Significance Index: -38.4700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -3.2036
    Cell Significance Index: -39.7400
  • Cell Name: neuron (CL0000540)
    Fold Change: -3.3611
    Cell Significance Index: -31.8600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -3.5344
    Cell Significance Index: -164.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** DLG2 is a large protein (approximately 260 kDa) that contains multiple binding domains, including PDZ (PSD-95/Discs Large/ZO-1), SH3 (Src Homology 3), and guanylate kinase domains. These domains enable DLG2 to interact with a wide range of proteins, including receptors, kinases, and adaptor proteins. The protein is characterized by its ability to bind to the NMDA receptor, which is a critical component of excitatory synaptic transmission. DLG2 also interacts with other key players in synaptic plasticity, such as the Ras/MAPK signaling pathway, which is involved in long-term potentiation and depression. **Pathways and Functions** DLG2 plays a central role in several key signaling pathways, including: 1. **Activation of NMDA receptors and postsynaptic events**: DLG2 interacts with the NMDA receptor, facilitating its activation and localization to the postsynaptic density. 2. **Assembly and cell surface presentation of NMDA receptors**: DLG2 helps to assemble and present NMDA receptors at the synapse, ensuring proper synaptic transmission. 3. **Ras activation upon Ca2+ influx through NMDA receptor**: DLG2 interacts with the Ras/MAPK signaling pathway, which is activated by Ca2+ influx through the NMDA receptor. 4. **Regulation of neuronal transmission**: DLG2 modulates neuronal transmission by regulating the activity of NMDA receptors and other synaptic proteins. 5. **Synaptic plasticity**: DLG2 is involved in the regulation of synaptic plasticity, including long-term potentiation and depression. **Clinical Significance** Dysregulation of DLG2 has been implicated in various neurological and psychiatric disorders, including: 1. **Schizophrenia**: DLG2 has been shown to be decreased in individuals with schizophrenia, suggesting a role in the disorder's pathophysiology. 2. **Autism spectrum disorder**: DLG2 has been found to be altered in individuals with autism spectrum disorder, suggesting a role in the disorder's neurobiological mechanisms. 3. **Neurodegenerative disorders**: DLG2 has been implicated in the pathophysiology of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Neuromuscular junction disorders**: DLG2 has been shown to be altered in individuals with neuromuscular junction disorders, such as myasthenia gravis. In conclusion, DLG2 is a critical component of the postsynaptic density, playing a pivotal role in the regulation of neuronal transmission and synaptic plasticity. Its dysregulation has been implicated in various neurological and psychiatric disorders, highlighting the importance of further research into the molecular mechanisms underlying these disorders.

Genular Protein ID: 2327923573

Symbol: DLG2_HUMAN

Name: Disks large homolog 2

UniProtKB Accession Codes:

Q15700 B7WNY8 F8W9V6 Q59G57 Q5H9Q4 Q68CQ8 Q6ZTA8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 3 CTD 1 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 24 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PIRSF 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 Reactome 7 RefSeq 5 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8755482

Title: Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins.

PubMed ID: 8755482

DOI: 10.1016/s0896-6273(00)80284-6

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15304517

Title: An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1.

PubMed ID: 15304517

DOI: 10.1074/jbc.m407575200

PubMed ID: 16630835

Title: SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses.

PubMed ID: 16630835

DOI: 10.1016/j.neuron.2006.04.005

PubMed ID: 19118189

Title: Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

PubMed ID: 19118189

DOI: 10.1523/jneurosci.3112-08.2008

PubMed ID: 19807924

Title: Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

PubMed ID: 19807924

DOI: 10.1186/1471-2172-10-53

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 17384233

Title: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.

PubMed ID: 17384233

DOI: 10.1110/ps.062657507

Sequence Information:

  • Length: 870
  • Mass: 97552
  • Checksum: BC51554590060E48
  • Sequence:
    • MFFACYCALR TNVKKYRYQD EDAPHDHSLP RLTHEVRGPE LVHVSEKNLS QIENVHGYVL 
QSHISPLKAS PAPIIVNTDT LDTIPYVNGT EIEYEFEEIT LERGNSGLGF SIAGGTDNPH 
IGDDPGIFIT KIIPGGAAAE DGRLRVNDCI LRVNEVDVSE VSHSKAVEAL KEAGSIVRLY 
VRRRRPILET VVEIKLFKGP KGLGFSIAGG VGNQHIPGDN SIYVTKIIDG GAAQKDGRLQ 
VGDRLLMVNN YSLEEVTHEE AVAILKNTSE VVYLKVGKPT TIYMTDPYGP PDITHSYSPP 
MENHLLSGNN GTLEYKTSLP PISPGRYSPI PKHMLVDDDY TRPPEPVYST VNKLCDKPAS 
PRHYSPVECD KSFLLSAPYS HYHLGLLPDS EMTSHSQHST ATRQPSMTLQ RAVSLEGEPR 
KVVLHKGSTG LGFNIVGGED GEGIFVSFIL AGGPADLSGE LQRGDQILSV NGIDLRGASH 
EQAAAALKGA GQTVTIIAQY QPEDYARFEA KIHDLREQMM NHSMSSGSGS LRTNQKRSLY 
VRAMFDYDKS KDSGLPSQGL SFKYGDILHV INASDDEWWQ ARRVMLEGDS EEMGVIPSKR 
RVERKERARL KTVKFNAKPG VIDSKGSFND KRKKSFIFSR KFPFYKNKEQ SEQETSDPER 
GQEDLILSYE PVTRQEINYT RPVIILGPMK DRINDDLISE FPDKFGSCVP HTTRPKRDYE 
VDGRDYHFVI SREQMEKDIQ EHKFIEAGQY NDNLYGTSVQ SVRFVAERGK HCILDVSGNA 
IKRLQVAQLY PIAIFIKPRS LEPLMEMNKR LTEEQAKKTY DRAIKLEQEF GEYFTAIVQG 
DTLEDIYNQC KLVIEEQSGP FIWIPSKEKL

Genular Protein ID: 2101876322

Symbol: E9PIJ9_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PIJ9

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 3 CTD 1 ChiTaRS 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 4 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 13 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMART 4 SMR 1 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 821
  • Mass: 91350
  • Checksum: D4C1241BB02B0979
  • Sequence:
    • MDCLCIVTTK QNQGRCPAQN CSVEAPAWMP VHHCTKYRYQ DEDAPHDHSL PRLTHEVRGP 
ELVHVSEKNL SQIENVHGYV LQSHISPLKA SPAPIIVNTD TLDTIPYVNG TEIEYEFEEI 
TLERGNSGLG FSIAGGTDNP HIGDDPGIFI TKIIPGGAAA EDGRLRVNDC ILRVNEVDVS 
EVSHSKAVEA LKEAGSIVRL YVRRRRPILE TVVEIKLFKG PKGLGFSIAG GVGNQHIPGD 
NSIYVTKIID GGAAQKDGRL QVGDRLLMVN NYSLEEVTHE EAVAILKNTS EVVYLKVGKP 
TTIYMTDPYG PPDITHSYSP PMENHLLSGN NGTLEYKTSL PPISPGRYSP IPKHMLVDDD 
YTSHSQHSTA TRQPSMTLQR AVSLEGEPRK VVLHKGSTGL GFNIVGGEDG EGIFVSFILA 
GGPADLSGEL QRGDQILSVN GIDLRGASHE QAAAALKGAG QTVTIIAQYQ PEDYARFEAK 
IHDLREQMMN HSMSSGSGSL RTNQKRSLYV RAMFDYDKSK DSGLPSQGLS FKYGDILHVI 
NASDDEWWQA RRVMLEGDSE EMGVIPSKRR VERKERARLK TVKFNAKPGV IDSKGDIPGL 
GDDGYGTKTL RGQEDLILSY EPVTRQEINY TRPVIILGPM KDRINDDLIS EFPDKFGSCV 
PHTTRPKRDY EVDGRDYHFV ISREQMEKDI QEHKFIEAGQ YNDNLYGTSV QSVRFVAERG 
KHCILDVSGN AIKRLQVAQL YPIAIFIKPR SLEPLMEMNK RLTEEQAKKT YDRAIKLEQE 
FGEYFTAIVQ GDTLEDIYNQ CKLVIEEQSG PFIWIPSKEK L

Genular Protein ID: 1190826332

Symbol: B7Z2T4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z2T4

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 GO 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 5 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMART 4 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 852
  • Mass: 95000
  • Checksum: EEAEA910AABC04A6
  • Sequence:
    • MFFACYCALR TNVKKYRYQD EDAPHDHSLP RLTHEVRGPE LVHVSEKNLS QIENVHGYVL 
QSHISPLKAS PAPIIVNTDT LDTIPYVNGT EIEYEFEEIT LERGNSGLGF SIAGGTDNPH 
IGDDPGIFIT KIIPGGAAAE DGRLRVNDCI LRVNEVDVSE VSHSKAVEAL KEAGSIVRLY 
VRRRRPILET VVEIKLFKGP KGLGFSIAGG VGNQHIPGDN SIYVTKIIDG GAAQKDGRLQ 
VGDRLLMVNN YSLEEVTHEE AVAILKNTSE VVYLKVGKPT TIYMTDPYGP PDITHSYSPP 
MENHLLSGNN GTLEYKTSLP PISPGRYSPI PKHMLVDDDY TRPPEPVYST VNKLCDKPAS 
PRHYSPVECD KSFLLSAPYS HYHLGLLPDS EMTSHSQHST ATRQPSMTLQ RAVSLEGEPR 
KVVLHKGSTG LGFNIVGGED GEGIFVSFIL AGGPADLSGE LQRGDQILSV NGIDLRGASH 
EQAAAALKGA GQTVTIIAQY QPEDYARFEA KIHDLREQMM NHSMSSGSGS LRTNQKRSLY 
VRAMFDYDKS KDSGLPSQGL SFKYGDILHV INASDDEWWQ ARRVMLEGDS EEMGVIPSKR 
RVERKERARL KTVKFNAKPG VIDSKGDIPG LGDDGYGTKT LRGQEDLILS YEPVTRQEIN 
YTRPVIILGP MKDRINDDLI SEFPDKFGSC VPHTTRPKRD YEVDGRDYHF VISREQMEKD 
IQEHKFIEAG QYNDNLYGTS VQSVRFVAER GKHCILDVSG NAIKRLQVAQ LYPIAIFIKP 
RSLEPLMEMN KRLTEEQAKK TYDRAIKLEQ EFGEYFTAIV QGDTLEDIYN QCKLVIEEQS 
GPFIWIPSKE KL

Genular Protein ID: 3060934413

Symbol: A0A994J7Q5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J7Q5

Database IDs:

ARBA 2 CDD 3 CTD 1 EMBL 6 Ensembl 2 GO 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 4 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 872
  • Mass: 97069
  • Checksum: 0E663CCE49EA8B5B
  • Sequence:
    • MSPVVKDPDC FTPMICHCKV ACTNNTLSLM FGCKKYRYQD EDAPHDHSLP RLTHEVRGPE 
LVHVSEKNLS QIENVHGYVL QSHISPLKAS PAPIIVNTDT LDTIPYVNGT EIEYEFEEIT 
LERGNSGLGF SIAGGTDNPH IGDDPGIFIT KIIPGGAAAE DGRLRVNDCI LRVNEVDVSE 
VSHSKAVEAL KEAGSIVRLY VRRRRPILET VVEIKLFKGP KGLGFSIAGG VGNQHIPGDN 
SIYVTKIIDG GAAQKDGRLQ VGDRLLMVNN YSLEEVTHEE AVAILKNTSE VVYLKVGKPT 
TIYMTDPYGP PDITHSYSPP MENHLLSGNN GTLEYKTSLP PISPGRYSPI PKHMLVDDDY 
TRPPEPVYST VNKLCDKPAS PRHYSPVECD KSFLLSAPYS HYHLGLLPDS EMTSHSQHST 
ATRQPSMTLQ RAVSLEGEPR KVVLHKGSTG LGFNIVGGED GEGIFVSFIL AGGPADLSGE 
LQRGDQILSV NGIDLRGASH EQAAAALKGA GQTVTIIAQY QPEDYARFEA KIHDLREQMM 
NHSMSSGSGS LRTNQKRSLY VRAMFDYDKS KDSGLPSQGL SFKYGDILHV INASDDEWWQ 
ARRVMLEGDS EEMGVIPSKR RVERKERARL KTVKFNAKPG VIDSKGDIPG LGDDGYGTKT 
LRGQEDLILS YEPVTRQEIN YTRPVIILGP MKDRINDDLI SEFPDKFGSC VPHTTRPKRD 
YEVDGRDYHF VISREQMEKD IQEHKFIEAG QYNDNLYGTS VQSVRFVAER GKHCILDVSG 
NAIKRLQVAQ LYPIAIFIKP RSLEPLMEMN KRLTEEQAKK TYDRAIKLEQ EFGEYFTAIV 
QGDTLEDIYN QCKLVIEEQS GPFIWIPSKE KL

Genular Protein ID: 4281906826

Symbol: A0A994J587_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J587

Database IDs:

ARBA 2 CDD 3 CTD 1 EMBL 6 Ensembl 2 GO 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 4 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 820
  • Mass: 91212
  • Checksum: A8682D73FAC9C2D9
  • Sequence:
    • MSPVVKDPDC FTPMICHCKV ACTNNTLSLM FGCKKYRYQD EDAPHDHSLP RLTHEVRGPE 
LVHVSEKNLS QIENVHGYVL QSHISPLKAS PAPIIVNTDT LDTIPYVNGT EIEYEFEEIT 
LERGNSGLGF SIAGGTDNPH IGDDPGIFIT KIIPGGAAAE DGRLRVNDCI LRVNEVDVSE 
VSHSKAVEAL KEAGSIVRLY VRRRRPILET VVEIKLFKGP KGLGFSIAGG VGNQHIPGDN 
SIYVTKIIDG GAAQKDGRLQ VGDRLLMVNN YSLEEVTHEE AVAILKNTSE VVYLKVGKPT 
TIYMTDPYGP PDITHSYSPP MENHLLSGNN GTLEYKTSLP PISPGRYSPI PKHMLVDDDY 
TSHSQHSTAT RQPSMTLQRA VSLEGEPRKV VLHKGSTGLG FNIVGGEDGE GIFVSFILAG 
GPADLSGELQ RGDQILSVNG IDLRGASHEQ AAAALKGAGQ TVTIIAQYQP EDYARFEAKI 
HDLREQMMNH SMSSGSGSLR TNQKRSLYVR AMFDYDKSKD SGLPSQGLSF KYGDILHVIN 
ASDDEWWQAR RVMLEGDSEE MGVIPSKRRV ERKERARLKT VKFNAKPGVI DSKGDIPGLG 
DDGYGTKTLR GQEDLILSYE PVTRQEINYT RPVIILGPMK DRINDDLISE FPDKFGSCVP 
HTTRPKRDYE VDGRDYHFVI SREQMEKDIQ EHKFIEAGQY NDNLYGTSVQ SVRFVAERGK 
HCILDVSGNA IKRLQVAQLY PIAIFIKPRS LEPLMEMNKR LTEEQAKKTY DRAIKLEQEF 
GEYFTAIVQG DTLEDIYNQC KLVIEEQSGP FIWIPSKEKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.