Details for: GRID2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stellate neuron (CL0000122)
Fold Change: 8.88
Marker Score: 47,724 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 8.4
Marker Score: 283,671 - Cell Name: granule cell (CL0000120)
Fold Change: 8.24
Marker Score: 62,140 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 7.24
Marker Score: 37,958 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 6.82
Marker Score: 22,861 - Cell Name: macroglial cell (CL0000126)
Fold Change: 5.36
Marker Score: 12,328 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 4.84
Marker Score: 2,169 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 4.72
Marker Score: 3,557 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 3.89
Marker Score: 16,262 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 3.86
Marker Score: 2,164 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 3.58
Marker Score: 1,184 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 3.38
Marker Score: 1,223 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 3.23
Marker Score: 1,554 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.09
Marker Score: 3,737 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 3
Marker Score: 1,566 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.94
Marker Score: 7,040 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.88
Marker Score: 57,213 - Cell Name: neuron (CL0000540)
Fold Change: 2.68
Marker Score: 10,930 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.57
Marker Score: 97,443 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.56
Marker Score: 10,622 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.51
Marker Score: 11,622 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.43
Marker Score: 3,009 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.41
Marker Score: 18,469 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.36
Marker Score: 747 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.34
Marker Score: 9,043 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.3
Marker Score: 885 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.29
Marker Score: 34,174 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.27
Marker Score: 1,129 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 2.18
Marker Score: 1,504 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.11
Marker Score: 1,226 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.96
Marker Score: 20,223 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.96
Marker Score: 120,239 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.89
Marker Score: 17,940 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.88
Marker Score: 2,269 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.88
Marker Score: 16,120 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.82
Marker Score: 3,702 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.77
Marker Score: 1,533 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.74
Marker Score: 1,049 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.67
Marker Score: 506 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.64
Marker Score: 2,043 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.63
Marker Score: 2,745 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.6
Marker Score: 1,166 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.6
Marker Score: 2,465 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.47
Marker Score: 1,688 - Cell Name: mural cell (CL0008034)
Fold Change: 1.45
Marker Score: 165,871 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.39
Marker Score: 3,964 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 1.38
Marker Score: 465 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.37
Marker Score: 868 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.36
Marker Score: 3,205 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.35
Marker Score: 12,712 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.35
Marker Score: 422 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.33
Marker Score: 48,975 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.32
Marker Score: 533 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.27
Marker Score: 1,784 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.26
Marker Score: 853 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.24
Marker Score: 19,374 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.22
Marker Score: 1,162 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.22
Marker Score: 496 - Cell Name: glial cell (CL0000125)
Fold Change: 1.19
Marker Score: 1,310 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.18
Marker Score: 488 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.14
Marker Score: 4,789 - Cell Name: dendritic cell (CL0000451)
Fold Change: 1.14
Marker Score: 781 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.13
Marker Score: 2,479 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.1
Marker Score: 504 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.08
Marker Score: 376 - Cell Name: Mueller cell (CL0000636)
Fold Change: 1.04
Marker Score: 1,445 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.03
Marker Score: 949 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.03
Marker Score: 676 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.02
Marker Score: 4,271 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.02
Marker Score: 961 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,755 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,984 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1
Marker Score: 1,241 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.99
Marker Score: 1,884 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 510 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 464 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,404 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.97
Marker Score: 20,797 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.94
Marker Score: 1,141 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.94
Marker Score: 376 - Cell Name: T cell (CL0000084)
Fold Change: 0.94
Marker Score: 1,617 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.94
Marker Score: 559 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,290 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.93
Marker Score: 442 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.92
Marker Score: 706 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,740 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 328 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.91
Marker Score: 236 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,284 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.87
Marker Score: 5,233 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.83
Marker Score: 1,509 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.8
Marker Score: 276 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.78
Marker Score: 219 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,259 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 704 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 399 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.74
Marker Score: 742 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.73
Marker Score: 2,582 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.73
Marker Score: 464
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4056038664
Symbol: GRID2_HUMAN
Name: Glutamate receptor ionotropic, delta-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9465309
Title: The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22.
PubMed ID: 9465309
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 27418511
Title: Structural basis for integration of GluD receptors within synaptic organizer complexes.
PubMed ID: 27418511
PubMed ID: 23611888
Title: A homozygous deletion in GRID2 causes a human phenotype with cerebellar ataxia and atrophy.
PubMed ID: 23611888
PubMed ID: 24078737
Title: Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans.
PubMed ID: 24078737
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 25841024
Title: GRID2 mutations span from congenital to mild adult-onset cerebellar ataxia.
PubMed ID: 25841024
Sequence Information:
- Length: 1007
- Mass: 113356
- Checksum: 8EF938AB7F1D6D26
- Sequence:
MEVFPFLLVL SVWWSRTWDS ANADSIIHIG AIFDESAKKD DEVFRTAVGD LNQNEEILQT EKITFSVTFV DGNNPFQAVQ EACELMNQGI LALVSSIGCT SAGSLQSLAD AMHIPHLFIQ RSTAGTPRSG CGLTRSNRND DYTLSVRPPV YLHDVILRVV TEYAWQKFII FYDSEYDIRG IQEFLDKVSQ QGMDVALQKV ENNINKMITT LFDTMRIEEL NRYRDTLRRA ILVMNPATAK SFITEVVETN LVAFDCHWII INEEINDVDV QELVRRSIGR LTIIRQTFPV PQNISQRCFR GNHRISSTLC DPKDPFAQNM EISNLYIYDT VLLLANAFHK KLEDRKWHSM ASLSCIRKNS KPWQGGRSML ETIKKGGVSG LTGELEFGEN GGNPNVHFEI LGTNYGEELG RGVRKLGCWN PVTGLNGSLT DKKLENNMRG VVLRVVTVLE EPFVMVSENV LGKPKKYQGF SIDVLDALSN YLGFNYEIYV APDHKYGSPQ EDGTWNGLVG ELVFKRADIG ISALTITPDR ENVVDFTTRY MDYSVGVLLR RAEKTVDMFA CLAPFDLSLW ACIAGTVLLV GLLVYLLNWL NPPRLQMGSM TSTTLYNSMW FVYGSFVQQG GEVPYTTLAT RMMMGAWWLF ALIVISSYTA NLAAFLTITR IESSIQSLQD LSKQTEIPYG TVLDSAVYEH VRMKGLNPFE RDSMYSQMWR MINRSNGSEN NVLESQAGIQ KVKYGNYAFV WDAAVLEYVA INDPDCSFYT IGNTVADRGY GIALQHGSPY RDVFSQRILE LQQNGDMDIL KHKWWPKNGQ CDLYSSVDTK QKGGALDIKS FAGVFCILAA GIVLSCFIAM LETWWNKRKG SRVPSKEDDK EIDLEHLHRR VNSLCTDDDS PHKQFSTSSI DLTPLDIDTL PTRQALEQIS DFRNTHITTT TFIPEQIQTL SRTLSAKAAS GFTFGNVPEH RTGPFRHRAP NGGFFRSPIK TMSSIPYQPT PTLGLNLGND PDRGTSI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.