Details for: GRID2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 274.1121
Cell Significance Index: -111.3600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 13.3379
Cell Significance Index: 25113.6700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 11.5777
Cell Significance Index: 253.5100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 10.3092
Cell Significance Index: 176.6700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.9418
Cell Significance Index: -19.5700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 8.0975
Cell Significance Index: 454.3900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 7.5580
Cell Significance Index: 334.3100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 7.1367
Cell Significance Index: 270.2500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 6.1770
Cell Significance Index: 2215.5700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 3.7724
Cell Significance Index: 231.8700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 3.7152
Cell Significance Index: 2569.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6420
Cell Significance Index: 529.9800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 2.5231
Cell Significance Index: 60.5100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.1961
Cell Significance Index: 14.8400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.1823
Cell Significance Index: 1820.1600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.0791
Cell Significance Index: 685.3500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.7769
Cell Significance Index: 80.8900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2720
Cell Significance Index: 18.2900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2423
Cell Significance Index: 109.9500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0129
Cell Significance Index: -23.7400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0353
Cell Significance Index: -47.9700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0743
Cell Significance Index: -10.8000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1486
Cell Significance Index: -110.0400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1634
Cell Significance Index: -123.6500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.1904
Cell Significance Index: -84.1700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1909
Cell Significance Index: -119.2100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.1960
Cell Significance Index: -107.0600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2038
Cell Significance Index: -114.9400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3252
Cell Significance Index: -93.5800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.4475
Cell Significance Index: -88.8100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.4638
Cell Significance Index: -9.1700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.5299
Cell Significance Index: -14.8100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.5528
Cell Significance Index: -99.6500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.5618
Cell Significance Index: -118.3200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.5618
Cell Significance Index: -8.0500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.5978
Cell Significance Index: -102.0800 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.7534
Cell Significance Index: -9.7700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.8161
Cell Significance Index: -112.0800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.8276
Cell Significance Index: -101.7600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.8803
Cell Significance Index: -25.1200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.9314
Cell Significance Index: -18.7000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.9725
Cell Significance Index: -51.0600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -1.0122
Cell Significance Index: -117.9600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -1.0830
Cell Significance Index: -124.0800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -1.0890
Cell Significance Index: -111.2400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.0893
Cell Significance Index: -35.6700 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -1.1161
Cell Significance Index: -12.1600 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -1.1357
Cell Significance Index: -11.8300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.3724
Cell Significance Index: -105.3200 - Cell Name: neural cell (CL0002319)
Fold Change: -1.5326
Cell Significance Index: -17.8800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.8030
Cell Significance Index: -57.4300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.8279
Cell Significance Index: -112.0700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.9700
Cell Significance Index: -124.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -2.1316
Cell Significance Index: -111.0300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -2.1400
Cell Significance Index: -74.9700 - Cell Name: glioblast (CL0000030)
Fold Change: -2.2876
Cell Significance Index: -14.3700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -2.2937
Cell Significance Index: -107.8000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -2.4467
Cell Significance Index: -110.9000 - Cell Name: neuron (CL0000540)
Fold Change: -2.4570
Cell Significance Index: -23.2900 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -2.4704
Cell Significance Index: -32.9600 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -2.5673
Cell Significance Index: -31.1200 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -2.6597
Cell Significance Index: -55.5100 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -2.6714
Cell Significance Index: -33.7100 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -2.7413
Cell Significance Index: -19.9300 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: -2.8204
Cell Significance Index: -22.1200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -2.8711
Cell Significance Index: -62.0300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -2.9120
Cell Significance Index: -135.7700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -2.9397
Cell Significance Index: -152.7100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -3.0570
Cell Significance Index: -78.5800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -3.0772
Cell Significance Index: -65.3100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -3.1491
Cell Significance Index: -109.4300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -3.1694
Cell Significance Index: -79.0600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -3.2409
Cell Significance Index: -118.9700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -3.2904
Cell Significance Index: -115.6200 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -3.4859
Cell Significance Index: -68.6100 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -3.5484
Cell Significance Index: -112.2300 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -3.5689
Cell Significance Index: -42.6800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -3.5756
Cell Significance Index: -86.6100 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -3.6718
Cell Significance Index: -73.2200 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -3.7287
Cell Significance Index: -52.1400 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -3.7450
Cell Significance Index: -80.0500 - Cell Name: radial glial cell (CL0000681)
Fold Change: -3.7613
Cell Significance Index: -22.3200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -3.7675
Cell Significance Index: -110.9700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -3.8339
Cell Significance Index: -109.9000 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: -3.9123
Cell Significance Index: -51.0600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -3.9772
Cell Significance Index: -114.5900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -4.0966
Cell Significance Index: -107.7200 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -4.1268
Cell Significance Index: -55.0100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -4.1563
Cell Significance Index: -110.9800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -4.2411
Cell Significance Index: -73.3300 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -4.2611
Cell Significance Index: -86.7100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -4.3609
Cell Significance Index: -91.2800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -4.4457
Cell Significance Index: -118.9200 - Cell Name: keratinocyte (CL0000312)
Fold Change: -4.4590
Cell Significance Index: -111.3700 - Cell Name: erythrocyte (CL0000232)
Fold Change: -4.5398
Cell Significance Index: -115.6700 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -4.5851
Cell Significance Index: -114.3400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -4.6320
Cell Significance Index: -124.1200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -4.6917
Cell Significance Index: -117.2800 - Cell Name: astrocyte (CL0000127)
Fold Change: -4.7265
Cell Significance Index: -54.1000 - Cell Name: flat midget bipolar cell (CL4033033)
Fold Change: -4.8673
Cell Significance Index: -60.5000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4056038664
Symbol: GRID2_HUMAN
Name: Glutamate receptor ionotropic, delta-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9465309
Title: The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22.
PubMed ID: 9465309
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 27418511
Title: Structural basis for integration of GluD receptors within synaptic organizer complexes.
PubMed ID: 27418511
PubMed ID: 23611888
Title: A homozygous deletion in GRID2 causes a human phenotype with cerebellar ataxia and atrophy.
PubMed ID: 23611888
PubMed ID: 24078737
Title: Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans.
PubMed ID: 24078737
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 25841024
Title: GRID2 mutations span from congenital to mild adult-onset cerebellar ataxia.
PubMed ID: 25841024
Sequence Information:
- Length: 1007
- Mass: 113356
- Checksum: 8EF938AB7F1D6D26
- Sequence:
MEVFPFLLVL SVWWSRTWDS ANADSIIHIG AIFDESAKKD DEVFRTAVGD LNQNEEILQT EKITFSVTFV DGNNPFQAVQ EACELMNQGI LALVSSIGCT SAGSLQSLAD AMHIPHLFIQ RSTAGTPRSG CGLTRSNRND DYTLSVRPPV YLHDVILRVV TEYAWQKFII FYDSEYDIRG IQEFLDKVSQ QGMDVALQKV ENNINKMITT LFDTMRIEEL NRYRDTLRRA ILVMNPATAK SFITEVVETN LVAFDCHWII INEEINDVDV QELVRRSIGR LTIIRQTFPV PQNISQRCFR GNHRISSTLC DPKDPFAQNM EISNLYIYDT VLLLANAFHK KLEDRKWHSM ASLSCIRKNS KPWQGGRSML ETIKKGGVSG LTGELEFGEN GGNPNVHFEI LGTNYGEELG RGVRKLGCWN PVTGLNGSLT DKKLENNMRG VVLRVVTVLE EPFVMVSENV LGKPKKYQGF SIDVLDALSN YLGFNYEIYV APDHKYGSPQ EDGTWNGLVG ELVFKRADIG ISALTITPDR ENVVDFTTRY MDYSVGVLLR RAEKTVDMFA CLAPFDLSLW ACIAGTVLLV GLLVYLLNWL NPPRLQMGSM TSTTLYNSMW FVYGSFVQQG GEVPYTTLAT RMMMGAWWLF ALIVISSYTA NLAAFLTITR IESSIQSLQD LSKQTEIPYG TVLDSAVYEH VRMKGLNPFE RDSMYSQMWR MINRSNGSEN NVLESQAGIQ KVKYGNYAFV WDAAVLEYVA INDPDCSFYT IGNTVADRGY GIALQHGSPY RDVFSQRILE LQQNGDMDIL KHKWWPKNGQ CDLYSSVDTK QKGGALDIKS FAGVFCILAA GIVLSCFIAM LETWWNKRKG SRVPSKEDDK EIDLEHLHRR VNSLCTDDDS PHKQFSTSSI DLTPLDIDTL PTRQALEQIS DFRNTHITTT TFIPEQIQTL SRTLSAKAAS GFTFGNVPEH RTGPFRHRAP NGGFFRSPIK TMSSIPYQPT PTLGLNLGND PDRGTSI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.