Cell ID: CL0000312

Cell Name: keratinocyte

CSI Thresholds:

Select	Context	Threshold
	Overall	25
	Anterior part of tongue + Healthy	654
	Anterior part of tongue	654
	Skin epidermis	647
	Skin epidermis + Healthy	647
	Gingiva + Gingivitis	204
	Gingivitis	204
	Posterior part of tongue + Healthy	181
	Posterior part of tongue	181
	Dermis + Healthy	32
	Dermis	32
	Scalp	29
	Scalp + Healthy	29
	Healthy	27
	Gingiva + Healthy	25
	Zone of skin	25
	Zone of skin + Healthy	25
	Breast + Breast cancer	17
	Breast	16
	Liver + Healthy	14
	Gingiva + Periodontitis	13
	Periodontitis	13
	Kidney	12
	Skin of body + Healthy	11
	Skin of body	11
	Liver	6
	Breast cancer	6
	Gingiva	5
	Skin of leg	5
	Skin of leg + Healthy	5
	Thymus + Healthy	3
	Thymus	3
	Yolk sac	1
	Yolk sac + Healthy	1
	Kidney + Healthy	-1

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

Synonyms: keratinized cell of epidermis, malpighian cell