Details for: MAP1B

Gene ID: 4131

Symbol: MAP1B

Ensembl ID: ENSG00000131711

Description: microtubule associated protein 1B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 302.7074
    Cell Significance Index: -142.9200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 269.1522
    Cell Significance Index: -109.3500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 114.7744
    Cell Significance Index: -109.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 39.2215
    Cell Significance Index: -154.7700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 8.4031
    Cell Significance Index: 100.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 6.7936
    Cell Significance Index: 381.2200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 6.7433
    Cell Significance Index: 354.0500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 6.7345
    Cell Significance Index: 45.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.1277
    Cell Significance Index: 315.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 4.3374
    Cell Significance Index: 291.6500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 4.0475
    Cell Significance Index: 97.0700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.6050
    Cell Significance Index: 1293.0500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.2617
    Cell Significance Index: 654.3000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.7992
    Cell Significance Index: 79.8800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.3620
    Cell Significance Index: 148.8700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 2.3443
    Cell Significance Index: 24.4200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.0576
    Cell Significance Index: 1423.1400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.6750
    Cell Significance Index: 20.7800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.5864
    Cell Significance Index: 203.3700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.4600
    Cell Significance Index: 25.0200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.4043
    Cell Significance Index: 30.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.9798
    Cell Significance Index: 44.4100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8785
    Cell Significance Index: 793.2400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.8529
    Cell Significance Index: 387.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2939
    Cell Significance Index: 13.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2355
    Cell Significance Index: 32.3400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1279
    Cell Significance Index: 4.8500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0757
    Cell Significance Index: 2.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0538
    Cell Significance Index: 73.1100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0329
    Cell Significance Index: 14.5300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0138
    Cell Significance Index: -25.5400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0236
    Cell Significance Index: -36.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0482
    Cell Significance Index: -26.3500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0490
    Cell Significance Index: -92.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0613
    Cell Significance Index: -45.3800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0641
    Cell Significance Index: -10.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0831
    Cell Significance Index: -2.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1034
    Cell Significance Index: -65.6500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1065
    Cell Significance Index: -2.2300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1071
    Cell Significance Index: -66.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1720
    Cell Significance Index: -126.1000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1821
    Cell Significance Index: -102.6800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.2176
    Cell Significance Index: -164.7000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2425
    Cell Significance Index: -51.0800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.2863
    Cell Significance Index: -54.4800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3573
    Cell Significance Index: -46.1700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.3578
    Cell Significance Index: -35.3900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.4229
    Cell Significance Index: -83.9300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4424
    Cell Significance Index: -127.2800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.4732
    Cell Significance Index: -85.3100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4835
    Cell Significance Index: -37.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.5109
    Cell Significance Index: -14.7200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5295
    Cell Significance Index: -6.6000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.5719
    Cell Significance Index: -62.2000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5984
    Cell Significance Index: -11.6800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.6076
    Cell Significance Index: -103.7500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6326
    Cell Significance Index: -64.6200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.7583
    Cell Significance Index: -93.2500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.8301
    Cell Significance Index: -120.6600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8609
    Cell Significance Index: -100.3300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.8667
    Cell Significance Index: -7.2800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.9742
    Cell Significance Index: -111.2000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.9925
    Cell Significance Index: -7.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.0682
    Cell Significance Index: -55.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -1.1092
    Cell Significance Index: -130.8100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.1207
    Cell Significance Index: -12.2100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.2421
    Cell Significance Index: -85.9000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.2926
    Cell Significance Index: -60.7500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.3418
    Cell Significance Index: -153.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.3872
    Cell Significance Index: -144.4500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.4600
    Cell Significance Index: -103.2600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.4915
    Cell Significance Index: -51.8300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.6098
    Cell Significance Index: -119.9800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.6235
    Cell Significance Index: -20.4900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.6802
    Cell Significance Index: -28.1200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.7157
    Cell Significance Index: -103.0000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.8840
    Cell Significance Index: -40.2700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.9781
    Cell Significance Index: -55.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.9970
    Cell Significance Index: -63.9600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -2.0922
    Cell Significance Index: -134.9800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -2.1671
    Cell Significance Index: -70.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -2.2987
    Cell Significance Index: -73.2100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.3404
    Cell Significance Index: -143.4900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -2.5454
    Cell Significance Index: -50.3300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.6662
    Cell Significance Index: -138.5000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -2.7291
    Cell Significance Index: -59.1300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.8425
    Cell Significance Index: -60.3300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -2.9023
    Cell Significance Index: -58.2700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.9396
    Cell Significance Index: -102.9800
  • Cell Name: neural cell (CL0002319)
    Fold Change: -3.0447
    Cell Significance Index: -35.5200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -3.3687
    Cell Significance Index: -88.5800
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -3.3969
    Cell Significance Index: -32.3200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -3.4379
    Cell Significance Index: -88.3700
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -3.5199
    Cell Significance Index: -22.9000
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -3.5570
    Cell Significance Index: -29.3600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -3.6132
    Cell Significance Index: -90.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -3.6161
    Cell Significance Index: -168.6000
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -3.6985
    Cell Significance Index: -51.8400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -3.7292
    Cell Significance Index: -22.1300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -3.7783
    Cell Significance Index: -138.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Microtubule-binding protein**: MAP1B interacts with microtubules, regulating their dynamics and organization. 2. **Axon extension and dendrite development**: MAP1B is essential for the extension of axons and development of dendrites during neuronal maturation. 3. **Synaptic plasticity**: MAP1B regulates synaptic plasticity, a critical mechanism underlying learning and memory. 4. **Neuronal migration and differentiation**: MAP1B is involved in the migration and differentiation of neurons during development. 5. **Cytoskeletal organization**: MAP1B contributes to the organization of the cytoskeleton, influencing cell shape and movement. **Pathways and Functions:** 1. **Microtubule dynamics**: MAP1B regulates microtubule dynamics, promoting microtubule polymerization and depolymerization. 2. **Axon guidance**: MAP1B is involved in axon guidance, influencing the formation of axonal tracts and synapses. 3. **Dendrite development**: MAP1B regulates dendrite development, shaping the structure and morphology of dendrites. 4. **Synaptic transmission**: MAP1B modulates synaptic transmission, influencing the strength and plasticity of synaptic connections. 5. **Cytoskeletal organization**: MAP1B contributes to the organization of the cytoskeleton, influencing cell shape, movement, and intracellular transport. **Clinical Significance:** 1. **Neurological disorders**: Abnormalities in MAP1B expression have been linked to various neurological disorders, including autism spectrum disorder, schizophrenia, and Alzheimer's disease. 2. **Neurodevelopmental disorders**: MAP1B dysregulation is associated with neurodevelopmental disorders, such as ADHD and autism spectrum disorder. 3. **Neurodegenerative diseases**: MAP1B has been implicated in neurodegenerative diseases, including Parkinson's disease and Huntington's disease. 4. **Therapeutic target**: MAP1B is a potential therapeutic target for the treatment of neurological disorders, offering a promising avenue for the development of novel therapeutic strategies. In conclusion, MAP1B is a critical regulator of neuronal development, function, and maintenance, and its dysregulation has been linked to various neurological disorders. Further research is necessary to fully elucidate the mechanisms by which MAP1B influences neuronal function and to identify potential therapeutic targets for the treatment of neurological disorders.

Genular Protein ID: 1756756511

Symbol: MAP1B_HUMAN

Name: Microtubule-associated protein 1B

UniProtKB Accession Codes:

P46821 A2BDK5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 CarbonylDB 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 52 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7806212

Title: Cloning of human microtubule-associated protein 1B and the identification of a related gene on chromosome 15.

PubMed ID: 7806212

DOI: 10.1006/geno.1994.1384

PubMed ID: 12684070

Title: Hmob3 brain-specific sequence is a part of phylogenetically conserved human MAP1B gene 3'-untranslated region.

PubMed ID: 12684070

DOI: 10.1016/s1389-0344(03)00003-0

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 12147674

Title: Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin.

PubMed ID: 12147674

DOI: 10.1083/jcb.200202055

PubMed ID: 15525354

Title: Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor.

PubMed ID: 15525354

DOI: 10.1111/j.1471-4159.2004.02799.x

PubMed ID: 16227972

Title: Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival.

PubMed ID: 16227972

DOI: 10.1038/nature04256

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18419581

Title: MAP1 structural organization in Drosophila: in vivo analysis of FUTSCH reveals heavy- and light-chain subunits generated by proteolytic processing at a conserved cleavage site.

PubMed ID: 18419581

DOI: 10.1042/bj20071449

PubMed ID: 18195017

Title: DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.

PubMed ID: 18195017

DOI: 10.1074/jbc.m706040200

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24089205

Title: Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites.

PubMed ID: 24089205

DOI: 10.1038/nature12606

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25902260

Title: Autism and intellectual disability-associated KIRREL3 interacts with neuronal proteins MAP1B and MYO16 with potential roles in neurodevelopment.

PubMed ID: 25902260

DOI: 10.1371/journal.pone.0123106

PubMed ID: 29738522

Title:

PubMed ID: 29738522

DOI: 10.1371/journal.pgen.1007281

PubMed ID: 30150678

Title: MAP1B mutations cause intellectual disability and extensive white matter deficit.

PubMed ID: 30150678

DOI: 10.1038/s41467-018-05595-6

PubMed ID: 31317654

Title: MAP1B related syndrome: Case presentation and review of literature.

PubMed ID: 31317654

DOI: 10.1002/ajmg.a.61280

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 33268592

Title: Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.

PubMed ID: 33268592

DOI: 10.1172/jci.insight.136046

Sequence Information:

  • Length: 2468
  • Mass: 270634
  • Checksum: 3FFDCB2E20049A8A
  • Sequence:
    • MATVVVEATE PEPSGSIANP AASTSPSLSH RFLDSKFYLL VVVGEIVTEE HLRRAIGNIE 
LGIRSWDTNL IECNLDQELK LFVSRHSARF SPEVPGQKIL HHRSDVLETV VLINPSDEAV 
STEVRLMITD AARHKLLVLT GQCFENTGEL ILQSGSFSFQ NFIEIFTDQE IGELLSTTHP 
ANKASLTLFC PEEGDWKNSN LDRHNLQDFI NIKLNSASIL PEMEGLSEFT EYLSESVEVP 
SPFDILEPPT SGGFLKLSKP CCYIFPGGRG DSALFAVNGF NMLINGGSER KSCFWKLIRH 
LDRVDSILLT HIGDDNLPGI NSMLQRKIAE LEEEQSQGST TNSDWMKNLI SPDLGVVFLN 
VPENLKNPEP NIKMKRSIEE ACFTLQYLNK LSMKPEPLFR SVGNTIDPVI LFQKMGVGKL 
EMYVLNPVKS SKEMQYFMQQ WTGTNKDKAE FILPNGQEVD LPISYLTSVS SLIVWHPANP 
AEKIIRVLFP GNSTQYNILE GLEKLKHLDF LKQPLATQKD LTGQVPTPVV KQTKLKQRAD 
SRESLKPAAK PLPSKSVRKE SKEETPEVTK VNHVEKPPKV ESKEKVMVKK DKPIKTETKP 
SVTEKEVPSK EEPSPVKAEV AEKQATDVKP KAAKEKTVKK ETKVKPEDKK EEKEKPKKEV 
AKKEDKTPIK KEEKPKKEEV KKEVKKEIKK EEKKEPKKEV KKETPPKEVK KEVKKEEKKE 
VKKEEKEPKK EIKKLPKDAK KSSTPLSEAK KPAALKPKVP KKEESVKKDS VAAGKPKEKG 
KIKVIKKEGK AAEAVAAAVG TGATTAAVMA AAGIAAIGPA KELEAERSLM SSPEDLTKDF 
EELKAEEVDV TKDIKPQLEL IEDEEKLKET EPVEAYVIQK EREVTKGPAE SPDEGITTTE 
GEGECEQTPE ELEPVEKQGV DDIEKFEDEG AGFEESSETG DYEEKAETEE AEEPEEDGEE 
HVCVSASKHS PTEDEESAKA EADAYIREKR ESVASGDDRA EEDMDEAIEK GEAEQSEEEA 
DEEDKAEDAR EEEYEPEKME AEDYVMAVVD KAAEAGGAEE QYGFLTTPTK QLGAQSPGRE 
PASSIHDETL PGGSESEATA SDEENREDQP EEFTATSGYT QSTIEISSEP TPMDEMSTPR 
DVMSDETNNE ETESPSQEFV NITKYESSLY SQEYSKPADV TPLNGFSEGS KTDATDGKDY 
NASASTISPP SSMEEDKFSR SALRDAYCSE VKASTTLDIK DSISAVSSEK VSPSKSPSLS 
PSPPSPLEKT PLGERSVNFS LTPNEIKVSA EAEVAPVSPE VTQEVVEEHC ASPEDKTLEV 
VSPSQSVTGS AGHTPYYQSP TDEKSSHLPT EVIEKPPAVP VSFEFSDAKD ENERASVSPM 
DEPVPDSESP IEKVLSPLRS PPLIGSESAY ESFLSADDKA SGRGAESPFE EKSGKQGSPD 
QVSPVSEMTS TSLYQDKQEG KSTDFAPIKE DFGQEKKTDD VEAMSSQPAL ALDERKLGDV 
SPTQIDVSQF GSFKEDTKMS ISEGTVSDKS ATPVDEGVAE DTYSHMEGVA SVSTASVATS 
SFPEPTTDDV SPSLHAEVGS PHSTEVDDSL SVSVVQTPTT FQETEMSPSK EECPRPMSIS 
PPDFSPKTAK SRTPVQDHRS EQSSMSIEFG QESPEQSLAM DFSRQSPDHP TVGAGVLHIT 
ENGPTEVDYS PSDMQDSSLS HKIPPMEEPS YTQDNDLSEL ISVSQVEASP STSSAHTPSQ 
IASPLQEDTL SDVAPPRDMS LYASLTSEKV QSLEGEKLSP KSDISPLTPR ESSPLYSPTF 
SDSTSAVKEK TATCHSSSSP PIDAASAEPY GFRASVLFDT MQHHLALNRD LSTPGLEKDS 
GGKTPGDFSY AYQKPEETTR SPDEEDYDYE SYEKTTRTSD VGGYYYEKIE RTTKSPSDSG 
YSYETIGKTT KTPEDGDYSY EIIEKTTRTP EEGGYSYDIS EKTTSPPEVS GYSYEKTERS 
RRLLDDISNG YDDSEDGGHT LGDPSYSYET TEKITSFPES EGYSYETSTK TTRTPDTSTY 
CYETAEKITR TPQASTYSYE TSDLCYTAEK KSPSEARQDV DLCLVSSCEY KHPKTELSPS 
FINPNPLEWF ASEEPTEESE KPLTQSGGAP PPPGGKQQGR QCDETPPTSV SESAPSQTDS 
DVPPETEECP SITADANIDS EDESETIPTD KTVTYKHMDP PPAPVQDRSP SPRHPDVSMV 
DPEALAIEQN LGKALKKDLK EKTKTKKPGT KTKSSSPVKK SDGKSKPLAA SPKPAGLKES 
SDKVSRVASP KKKESVEKAA KPTTTPEVKA ARGEEKDKET KNAANASASK SAKTATAGPG 
TTKTTKSSAV PPGLPVYLDL CYIPNHSNSK NVDVEFFKRV RSSYYVVSGN DPAAEEPSRA 
VLDALLEGKA QWGSNMQVTL IPTHDSEVMR EWYQETHEKQ QDLNIMVLAS SSTVVMQDES 
FPACKIEL

Genular Protein ID: 4008260027

Symbol: A2BDK6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A2BDK6

Database IDs:

ARBA 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 3 IntAct 1 InterPro 2 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12684070

Title: Hmob3 brain-specific sequence is a part of phylogenetically conserved human MAP1B gene 3'-untranslated region.

PubMed ID: 12684070

DOI: 10.1016/S1389-0344(03)00003-0

Sequence Information:

  • Length: 2342
  • Mass: 256710
  • Checksum: AC79CA46A1437B11
  • Sequence:
    • MITDAARHKL LVLTGQCFEN TGELILQSGS FSFQNFIEIF TDQEIGELLS TTHPANKASL 
TLFCPEEGDW KNSNLDRHNL QDFINIKLNS ASILPEMEGL SEFTEYLSES VEVPSPFDIL 
EPPTSGGFLK LSKPCCYIFP GGRGDSALFA VNGFNMLING GSERKSCFWK LIRHLDRVDS 
ILLTHIGDDN LPGINSMLQR KIAELEEEQS QGSTTNSDWM KNLISPDLGV VFLNVPENLK 
NPEPNIKMKR SIEEACFTLQ YLNKLSMKPE PLFRSVGNTI DPVILFQKMG VGKLEMYVLN 
PVKSSKEMQY FMQQWTGTNK DKAEFILPNG QEVDLPISYL TSVSSLIVWH PANPAEKIIR 
VLFPGNSTQY NILEGLEKLK HLDFLKQPLA TQKDLTGQVP TPVVKQTKLK QRADSRESLK 
PAAKPLPSKS VRKESKEETP EVTKVNHVEK PPKVESKEKV MVKKDKPVKT ETKPSVTEKE 
VPSKEEPSPV KAEVAEKQAT DVKPKAAKEK TVKKETKVKP EDKKEEKEKP KKEVAKKEDK 
TPIKKEEKPK KEEVKKEVKK EIKKEEKKEP KKEVKKETPP KEVKKEVKKE EKKEVKKEEK 
EPKKEIKKLP KDAKKSSTPL SEAKKPAALK PKVPKKEESV KKDSVAAGKP KEKGKIKVIK 
KEGKAAEAVA AAVGTGATTA AVMAAAGIAA IGPAKELEAE RSLMSSPEDL TKDFEELKAE 
EVDVTKDIKP QLELIEDEEK LKETEPVEAY VIQKEREVTK GPAESPDEGI TTTEGEGECE 
QTPEELEPVE KQGVDDIEKF EDEGAGFEES SETGDYEEKA ETEEAEEPEE DGEEHVCVSA 
SKHSPTEDEE SAKAEADAYI REKRESVASG DDRAEEDMDE AIEKGEAEQS EEEADEEDKA 
EDAREEEYEP EKMEAEDYVM AVVDKAAEAG GAEEQYGFLT TPTKQLGAQS PGREPASSIH 
DETLPGGSES EATASDEENR EDQPEEFTAT SGYTQSTIEI SSEPTPMDEM STPRDVMSDE 
TNNEETESPS QEFVNITKYE SSLYSQEYSK PADVTPLNGF SEGSKTDATD GKDYNASAST 
ISPPSSMEED KFSRSALRDA YCSEVKASTT LDIKDSISAV SSEKVSPSKS PSLSPSPPSP 
LEKTPLGERS VNFSLTPNEI KVSAEAEVAP VSPEVTQEVV EEHCASPEDK TLEVVSPSQS 
VTGSAGHTPY YQSPTDEKSS HLPTEVIEKP PAVPVSFEFS DAKDENERAS VSPMDEPVPD 
SESPIEKVLS PLRSPPLIGS ESAYESFLSA DDKASGRGAE SPFEEKSGKQ GSPDQVSPVS 
EMTSTSLYQD KQEGKSTDFA PIKEDFGQEK KTDDVEAMSS QPALALDERK LGDVSPTQID 
VSQFGSFKED TKMSISEGTV SDKSATPVDE GVAEDTYSHM EGVASVSTAS VATSSFPEPT 
TDDVSPSLHA EVGSPHSTEV DDSLSVSVVQ TPTTFQETEM SPSKEECPRP MSISPPDFSP 
KTAKSRTPVQ DHRSEQSSMS IEFGQESPEQ SLAMDFSRQS PDHPTVGAGV LHITENGPTE 
VDYSPSDMQD SSLSHKIPPM EEPSYTQDND LSELISVSQV EASPSTSSAH TPSQIASPLQ 
EDTLSDVAPP RDMSLYASLT SEKVQSLEGE KLSPKSDISP LTPRESSPLY SPTFSDSTSA 
VKEKTATCHS SSSPPIDAAS AEPYGFRASV LFDTMQHHLA LNRDLSTPGL EKDSGGKTPG 
DFSYAYQKPE ETTRSPDEED YDYESYEKTT RTSDVGGYYY EKIERTTKSP SDSGYSYETI 
GKTTKTPEDG DYSYEIIEKT TRTPEEGGYS YDISEKTTSP PEVSGYSYEK TERSRRLLDD 
ISNGYDDSED GGHTLGDPSY SYETTEKITS FPESEGYSYE TSTKTTRTPD TSTYCYETAE 
KITRTPQAST YSYETSDLCY TAEKKSPSEA RQDVDLCLVS SCEYKHPKTE LSPSFINPNP 
LEWFASEEPT EESEKPLTQS GGAPPPPGGK QQGRQCDETP PTSVSESAPS QTDSDVPPET 
EECPSITADA NIDSEDESET IPTDKTVTYK HMDPPPAPVQ DRSPSPRHPD VSMVDPEALA 
IEQNLGKALK KDLKEKTKTK KPGTKTKSSS PVKKSDGKSK PLAASPKPAG LKESSDKVSR 
VASPKKKESV EKAAKPTTTP EVKAARGEEK DKETKNAANA SASKSAKTAT AGPGTTKTTK 
SSAVPPGLPV YLDLCYIPNH SNSKNVDVEF FKRVRSSYYV VSGNDPAAEE PSRAVLDALL 
EGKAQWGSNM QVTLIPTHDS EVMREWYQET HEKQQDLNIM VLASSSTVVM QDESFPACKI 
EL

Genular Protein ID: 4205091310

Symbol: Q6PJD3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PJD3

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 12 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 693
  • Mass: 77999
  • Checksum: D00A38D5E1E53D17
  • Sequence:
    • MATVVVEATE PEPSGSIANP AASTSPSLSH RFLDSKFYLL VVVGEIVTEE HLRRAIGNIE 
LGIRSWDTNL IECNLDQELK LFVSRHSARF SPEVPGQKIL HHRSDVLETV VLINPSDEAV 
STEVRLMITD AARHKLLVLT GQCFENTGEL ILQSGSFSFQ NFIEIFTDQE IGELLSTTHP 
ANKASLTLFC PEEGDWKNSN LDRHNLQDFI NIKLNSASIL PEMEGLSEFT EYLSESVEVP 
SPFDILEPPT SGGFLKLSKP CCYIFPGGRG DSALFAVNGF NMLINGGSER KSCFWKLIRH 
LDRVDSILLT HIGDDNLPGI NSMLQRKIAE LEEEQSQGST TNSDWMKNLI SPDLGVVFLN 
VPENLKNPEP NIKMKRSIEE ACFTLQYLNK LSMKPEPLFR SVGNTIDPVI LFQKMGVGKL 
EMYVLNPVKS SKEMQYFMQQ WTGTNKDKAE FILPNGQEVD LPISYLTSVS SLIVWHPANP 
AEKIIRVLFP GNSTQYNILE GLEKLKHLDF LKQPLATQKD LTGQVPTPVV KQTKLKQRAD 
SRESLKPAAK PLPSKSVRKE SKEETPEVTK VNHVEKPPKV ESKEKVMVKK DKPVKTETKP 
SVTEKEVPSK EEPSPVKAEV AEKQATDVKP KAAKEKTVKK ETKVKPEDKK EEKEKPKKEV 
AKKEDKTPIK KEEKPKKKKK KKKKKKKKKK KKK

Genular Protein ID: 1834738669

Symbol: Q86X89_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86X89

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 2 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 685
  • Mass: 76961
  • Checksum: 60D5A42213F46EE4
  • Sequence:
    • MATVVVEATE PEPSGSIANP AASTSPSLSH RFLDSKFYLL VVVGEIVTEE HLRRAIGNIE 
LGIRSWDTNL IECNLDQELK LFVSRHSARF SPEVPGQKIL HHRSDVLETV VLINPSDEAV 
STEVRLMITD AARHKLLVLT GQCFENTGEL ILQSGSFSFQ NFIEIFTDQE IGELLSTTHP 
ANKASLTLFC PEEGDWKNSN LDRHNLQDFI NIKLNSASIL PEMEGLSEFT EYLSESVEVP 
SPFDILEPPT SGGFLKLSKP CCYIFPGGRG DSALFAVNGF NMLINGGSER KSCFWKLIRH 
LDRVDSILLT HIGDDNLPGI NSMLQRKIAE LEEEQSQGST TNSDWMKNLI SPDLGVVFLN 
VPENLKNPEP NIKMKRSIEE ACFTLQYLNK LSMKPEPLFR SVGNTIDPVI LFQKMGVGKL 
EMYVLNPVKS SKEMQYFMQQ WTGTNKDKAE FILPNGQEVD LPISYLTSVS SLIVWHPANP 
AEKIIRVLFP GNSTQYNILE GLEKLKHLDF LKQPLATQKD LTGQVPTPVV KQTKLKQRAD 
SRESLKPAAK PLPSKSVRKE SKEETPEVTK VNHVEKPPKV ESKEKVMVKK DKPIKTETKP 
SVTEKEVPSK EEPSPVKAEV AEKQATDVKP KAAKEKTVKK ETKVKPEDKK EEKEKPKKEV 
AKKEDKTPIK KEEKPKKEEV KKKKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.