Details for: IL20
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 1.6627
Cell Significance Index: 4.9500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.6754
Cell Significance Index: 47.7700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.3156
Cell Significance Index: 8.5900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1813
Cell Significance Index: 80.1700 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.1092
Cell Significance Index: 1.3800 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.0686
Cell Significance Index: 0.8200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0417
Cell Significance Index: 1.9600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0373
Cell Significance Index: 2.7800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0030
Cell Significance Index: 0.1400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0003
Cell Significance Index: -0.0100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0024
Cell Significance Index: -4.6000 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0026
Cell Significance Index: -0.0500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0062
Cell Significance Index: -4.7300 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0062
Cell Significance Index: -3.3600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0078
Cell Significance Index: -5.8100 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.0081
Cell Significance Index: -0.1000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0088
Cell Significance Index: -4.9500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0099
Cell Significance Index: -1.2800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0119
Cell Significance Index: -0.3300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0124
Cell Significance Index: -1.2700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.0149
Cell Significance Index: -0.2300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0163
Cell Significance Index: -0.4200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0165
Cell Significance Index: -4.7500 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.0173
Cell Significance Index: -0.2100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0204
Cell Significance Index: -3.6800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0227
Cell Significance Index: -4.5500 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: -0.0239
Cell Significance Index: -0.1200 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -0.0275
Cell Significance Index: -0.3800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0279
Cell Significance Index: -5.8800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0296
Cell Significance Index: -3.6400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0298
Cell Significance Index: -0.3400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0319
Cell Significance Index: -4.3800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0331
Cell Significance Index: -5.6600 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0369
Cell Significance Index: -0.9200 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.0384
Cell Significance Index: -0.3800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0395
Cell Significance Index: -4.5300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0531
Cell Significance Index: -1.0500 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.0552
Cell Significance Index: -0.3400 - Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: -0.0570
Cell Significance Index: -0.9800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0663
Cell Significance Index: -5.0900 - Cell Name: immature NK T cell (CL0000914)
Fold Change: -0.0687
Cell Significance Index: -0.8800 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: -0.0777
Cell Significance Index: -0.8500 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.0882
Cell Significance Index: -1.1300 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: -0.0882
Cell Significance Index: -1.0500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0926
Cell Significance Index: -4.8100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0945
Cell Significance Index: -4.9600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1068
Cell Significance Index: -3.7100 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: -0.1123
Cell Significance Index: -0.9100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1133
Cell Significance Index: -2.9800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.1191
Cell Significance Index: -1.0000 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1205
Cell Significance Index: -3.0100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1207
Cell Significance Index: -4.4300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1210
Cell Significance Index: -4.2400 - Cell Name: Langerhans cell (CL0000453)
Fold Change: -0.1280
Cell Significance Index: -1.2200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1284
Cell Significance Index: -4.2100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1327
Cell Significance Index: -3.9100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1413
Cell Significance Index: -4.5000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1829
Cell Significance Index: -2.5000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1891
Cell Significance Index: -5.4200 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1892
Cell Significance Index: -4.8200 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1899
Cell Significance Index: -4.6000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2028
Cell Significance Index: -4.4400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2059
Cell Significance Index: -4.3700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2060
Cell Significance Index: -2.9500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2079
Cell Significance Index: -5.5500 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2119
Cell Significance Index: -5.1700 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.2144
Cell Significance Index: -4.2800 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.2156
Cell Significance Index: -2.2900 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: -0.2203
Cell Significance Index: -2.8800 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.2205
Cell Significance Index: -3.7700 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2286
Cell Significance Index: -5.2800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2359
Cell Significance Index: -4.3600 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.2378
Cell Significance Index: -4.6500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2448
Cell Significance Index: -4.9200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2569
Cell Significance Index: -4.3000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2636
Cell Significance Index: -4.4400 - Cell Name: myoepithelial cell (CL0000185)
Fold Change: -0.2671
Cell Significance Index: -3.0300 - Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.2748
Cell Significance Index: -4.4500 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.2781
Cell Significance Index: -5.8000 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.2825
Cell Significance Index: -2.9800 - Cell Name: basal cell (CL0000646)
Fold Change: -0.2899
Cell Significance Index: -3.4500 - Cell Name: salivary gland cell (CL0009005)
Fold Change: -0.2911
Cell Significance Index: -3.6200 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.2928
Cell Significance Index: -3.0200 - Cell Name: monocyte (CL0000576)
Fold Change: -0.2929
Cell Significance Index: -3.3700 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.3024
Cell Significance Index: -4.3900 - Cell Name: leukocyte (CL0000738)
Fold Change: -0.3038
Cell Significance Index: -5.1600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.3049
Cell Significance Index: -5.9500 - Cell Name: ionocyte (CL0005006)
Fold Change: -0.3070
Cell Significance Index: -3.2100 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.3087
Cell Significance Index: -3.9800 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.3114
Cell Significance Index: -4.2700 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.3226
Cell Significance Index: -5.7000 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.3241
Cell Significance Index: -5.2300 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.3245
Cell Significance Index: -4.5000 - Cell Name: myeloid cell (CL0000763)
Fold Change: -0.3258
Cell Significance Index: -4.3300 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: -0.3259
Cell Significance Index: -4.0900 - Cell Name: endocrine cell (CL0000163)
Fold Change: -0.3295
Cell Significance Index: -3.9800 - Cell Name: lymphocyte (CL0000542)
Fold Change: -0.3308
Cell Significance Index: -4.5000 - Cell Name: acinar cell (CL0000622)
Fold Change: -0.3320
Cell Significance Index: -4.1700 - Cell Name: microglial cell (CL0000129)
Fold Change: -0.3325
Cell Significance Index: -3.9100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.3339
Cell Significance Index: -4.9300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3254646150
Symbol: IL20_HUMAN
Name: Interleukin-20
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11163236
Title: Interleukin 20: discovery, receptor identification, and role in epidermal function.
PubMed ID: 11163236
PubMed ID: 16511554
Title: Interleukin-20 promotes angiogenesis in a direct and indirect manner.
PubMed ID: 16511554
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 11564763
Title: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.
PubMed ID: 11564763
PubMed ID: 11706020
Title: Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.
PubMed ID: 11706020
PubMed ID: 16908179
Title: Tissue microarray analysis of interleukin-20 expression.
PubMed ID: 16908179
PubMed ID: 16709143
Title: Ultraviolet B light stimulates interleukin-20 expression by human epithelial keratinocytes.
PubMed ID: 16709143
PubMed ID: 17277128
Title: The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
PubMed ID: 17277128
PubMed ID: 23614738
Title: Studies of Jak/STAT3 expression and signalling in psoriasis identifies STAT3-Ser727 phosphorylation as a modulator of transcriptional activity.
PubMed ID: 23614738
DOI: 10.1111/exd.12128
PubMed ID: 28424238
Title: IL-20 Signaling in Activated Human Neutrophils Inhibits Neutrophil Migration and Function.
PubMed ID: 28424238
PubMed ID: 34403503
Title: IL-20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation.
PubMed ID: 34403503
DOI: 10.1111/imm.13403
PubMed ID: 22802649
Title: Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.
PubMed ID: 22802649
Sequence Information:
- Length: 176
- Mass: 20072
- Checksum: 8385992500B6C447
- Sequence:
MKASSLAFSL LSAAFYLLWT PSTGLKTLNL GSCVIATNLQ EIRNGFSEIR GSVQAKDGNI DIRILRRTES LQDTKPANRC CLLRHLLRLY LDRVFKNYQT PDHYTLRKIS SLANSFLTIK KDLRLCHAHM TCHCGEEAMK KYSQILSHFE KLEPQAAVVK ALGELDILLQ WMEETE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.