Details for: H3 3A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 671.7017
Cell Significance Index: -104.4800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 500.6241
Cell Significance Index: -126.9800 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 464.3794
Cell Significance Index: -191.3000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 410.5713
Cell Significance Index: -193.8400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 386.9279
Cell Significance Index: -199.0300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 290.5865
Cell Significance Index: -194.9900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 122.8917
Cell Significance Index: -151.5200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 46.1449
Cell Significance Index: -182.0900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 36.8685
Cell Significance Index: -113.2400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 26.8484
Cell Significance Index: -58.7600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 14.8615
Cell Significance Index: 274.6800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 14.2514
Cell Significance Index: 495.2300 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 13.6670
Cell Significance Index: 114.8000 - Cell Name: peg cell (CL4033014)
Fold Change: 11.6256
Cell Significance Index: 268.5900 - Cell Name: kidney cell (CL1000497)
Fold Change: 11.5252
Cell Significance Index: 92.0200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 11.2805
Cell Significance Index: 236.1200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 10.5800
Cell Significance Index: 278.2000 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 10.3778
Cell Significance Index: 132.9100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 9.9804
Cell Significance Index: 108.5000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 7.7909
Cell Significance Index: 918.7800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 7.7162
Cell Significance Index: 87.6600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 6.8778
Cell Significance Index: 443.7200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 6.4134
Cell Significance Index: 880.7400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 6.3543
Cell Significance Index: 781.3200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 6.3177
Cell Significance Index: 1138.8900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 5.9444
Cell Significance Index: 3246.3800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 5.6901
Cell Significance Index: 424.0800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 5.6431
Cell Significance Index: 2494.9700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 5.5253
Cell Significance Index: 390.7800 - Cell Name: odontoblast (CL0000060)
Fold Change: 5.3654
Cell Significance Index: 687.8200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 5.2062
Cell Significance Index: 47.9400 - Cell Name: lactocyte (CL0002325)
Fold Change: 5.1001
Cell Significance Index: 658.8900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.9163
Cell Significance Index: 229.2200 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 4.6868
Cell Significance Index: 33.6600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 4.6183
Cell Significance Index: 217.0600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 4.5957
Cell Significance Index: 241.2900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 4.4408
Cell Significance Index: 130.4200 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 4.4038
Cell Significance Index: 77.8200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 4.0787
Cell Significance Index: 111.0200 - Cell Name: theca cell (CL0000503)
Fold Change: 2.7659
Cell Significance Index: 16.2500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.5423
Cell Significance Index: 142.6600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.2921
Cell Significance Index: 65.7100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.4210
Cell Significance Index: 140.5700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.3426
Cell Significance Index: 153.8200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.3034
Cell Significance Index: 67.7100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.8387
Cell Significance Index: 143.2200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6980
Cell Significance Index: 132.8400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.6880
Cell Significance Index: 504.4700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.6292
Cell Significance Index: 476.2400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2304
Cell Significance Index: 82.6300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.2091
Cell Significance Index: 3.5000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2026
Cell Significance Index: 12.7700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1754
Cell Significance Index: 5.0600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.1073
Cell Significance Index: 8.5000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0294
Cell Significance Index: -3.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0691
Cell Significance Index: -130.1000 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.0701
Cell Significance Index: -0.5400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0829
Cell Significance Index: -16.6200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1139
Cell Significance Index: -210.1200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1296
Cell Significance Index: -199.5400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1300
Cell Significance Index: -6.5700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1516
Cell Significance Index: -206.0900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1682
Cell Significance Index: -124.6000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1925
Cell Significance Index: -38.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.2615
Cell Significance Index: -166.0700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2674
Cell Significance Index: -150.8300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.3688
Cell Significance Index: -230.2900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.3899
Cell Significance Index: -176.9800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.4118
Cell Significance Index: -14.4700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.4232
Cell Significance Index: -121.7800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.5223
Cell Significance Index: -21.4000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.7040
Cell Significance Index: -17.9900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.9571
Cell Significance Index: -201.6000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.9637
Cell Significance Index: -156.7300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.1147
Cell Significance Index: -162.0400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -1.3900
Cell Significance Index: -151.2000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.5886
Cell Significance Index: -50.8800 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.5894
Cell Significance Index: -27.4000 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -1.6781
Cell Significance Index: -14.4200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.7136
Cell Significance Index: -47.8900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.7239
Cell Significance Index: -132.2900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.7489
Cell Significance Index: -182.1000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.7972
Cell Significance Index: -38.9400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -1.7981
Cell Significance Index: -81.5000 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.8337
Cell Significance Index: -11.2900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.9527
Cell Significance Index: -29.2600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -2.2620
Cell Significance Index: -156.4300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -2.3434
Cell Significance Index: -27.9400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -2.9695
Cell Significance Index: -79.2900 - Cell Name: sensory neuron (CL0000101)
Fold Change: -3.0392
Cell Significance Index: -17.2800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -3.1842
Cell Significance Index: -195.2200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -3.2335
Cell Significance Index: -95.2400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -3.4228
Cell Significance Index: -51.5800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -3.8354
Cell Significance Index: -102.6000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -3.8795
Cell Significance Index: -52.9300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -3.9566
Cell Significance Index: -175.0100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -4.1526
Cell Significance Index: -106.7400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -4.2301
Cell Significance Index: -90.0900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -4.2605
Cell Significance Index: -156.4000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -4.5626
Cell Significance Index: -149.3800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3685484018
Symbol: H33_HUMAN
Name: Histone H3.3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2859593
Title: Structure of a human histone cDNA: evidence that basally expressed histone genes have intervening sequences and encode polyadenylylated mRNAs.
PubMed ID: 2859593
PubMed ID: 3031613
Title: Unusual structure, evolutionary conservation of non-coding sequences and numerous pseudogenes characterize the human H3.3 histone multigene family.
PubMed ID: 3031613
PubMed ID: 8586426
Title: The human replacement histone H3.3B gene (H3F3B).
PubMed ID: 8586426
PubMed ID: 15498874
Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.
PubMed ID: 15498874
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7309716
Title: Human spleen histone H3. Isolation and amino acid sequence.
PubMed ID: 7309716
PubMed ID: 16185088
Title: Modifications of human histone H3 variants during mitosis.
PubMed ID: 16185088
DOI: 10.1021/bi050906n
PubMed ID: 10464286
Title: Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.
PubMed ID: 10464286
PubMed ID: 11242053
Title: Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
PubMed ID: 11242053
DOI: 10.1038/35065132
PubMed ID: 11856369
Title: Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation.
PubMed ID: 11856369
PubMed ID: 12560483
Title: Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase.
PubMed ID: 12560483
DOI: 10.1093/nar/gkg176
PubMed ID: 14718166
Title: Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.
PubMed ID: 14718166
PubMed ID: 15471871
Title: Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1.
PubMed ID: 15471871
PubMed ID: 15525939
Title: Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.
PubMed ID: 15525939
DOI: 10.1038/nature03114
PubMed ID: 15345777
Title: Human PAD4 regulates histone arginine methylation levels via demethylimination.
PubMed ID: 15345777
PubMed ID: 15776021
Title: Variant histone H3.3 marks promoters of transcriptionally active genes during mammalian cell division.
PubMed ID: 15776021
PubMed ID: 15681610
Title: The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.
PubMed ID: 15681610
DOI: 10.1101/gad.1267105
PubMed ID: 15684425
Title: Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.
PubMed ID: 15684425
PubMed ID: 15851689
Title: Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes.
PubMed ID: 15851689
PubMed ID: 16258499
Title: Histone H3.3 deposition at E2F-regulated genes is linked to transcription.
PubMed ID: 16258499
PubMed ID: 16267050
Title: Expression patterns and post-translational modifications associated with mammalian histone H3 variants.
PubMed ID: 16267050
PubMed ID: 16457588
Title: Mass spectrometric characterization of human histone H3: a bird's eye view.
PubMed ID: 16457588
DOI: 10.1021/pr050266a
PubMed ID: 16497732
Title: Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17.
PubMed ID: 16497732
DOI: 10.1210/me.2005-0365
PubMed ID: 18079182
Title: PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation.
PubMed ID: 18079182
DOI: 10.1101/gad.447007
PubMed ID: 16567635
Title: Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4.
PubMed ID: 16567635
PubMed ID: 17194708
Title: Organismal differences in post-translational modifications in histones H3 and H4.
PubMed ID: 17194708
PubMed ID: 17189264
Title: Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification.
PubMed ID: 17189264
PubMed ID: 17898714
Title: Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.
PubMed ID: 17898714
DOI: 10.1038/nature06166
PubMed ID: 18077460
Title: Arginine methylation of the histone H3 tail impedes effector binding.
PubMed ID: 18077460
PubMed ID: 18066052
Title: Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation.
PubMed ID: 18066052
DOI: 10.1038/ncb1668
PubMed ID: 19520870
Title: Acetylation of histone H3 at the nucleosome dyad alters DNA-histone binding.
PubMed ID: 19520870
PubMed ID: 19783980
Title: JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.
PubMed ID: 19783980
DOI: 10.1038/nature08448
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20850016
Title: Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.
PubMed ID: 20850016
PubMed ID: 20504901
Title: The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3.
PubMed ID: 20504901
DOI: 10.1101/gad.566910
PubMed ID: 20228790
Title: Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.
PubMed ID: 20228790
DOI: 10.1038/nature08839
PubMed ID: 21925322
Title: Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.
PubMed ID: 21925322
PubMed ID: 22195965
Title: A specific function for the histone chaperone NASP to fine-tune a reservoir of soluble H3-H4 in the histone supply chain.
PubMed ID: 22195965
PubMed ID: 22901803
Title: PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
PubMed ID: 22901803
PubMed ID: 22387026
Title: Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA.
PubMed ID: 22387026
PubMed ID: 22483618
Title: Lysyl oxidase-like 2 deaminates lysine 4 in histone H3.
PubMed ID: 22483618
PubMed ID: 27392148
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 22389435
Title: Lysine succinylation and lysine malonylation in histones.
PubMed ID: 22389435
PubMed ID: 23415232
Title: Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer.
PubMed ID: 23415232
PubMed ID: 24681537
Title: Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.
PubMed ID: 24681537
PubMed ID: 27735137
Title: Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.
PubMed ID: 27735137
DOI: 10.1111/febs.13922
PubMed ID: 27105113
Title: Dynamic competing histone H4 K5K8 acetylation and butyrylation are hallmarks of highly active gene promoters.
PubMed ID: 27105113
PubMed ID: 27105115
Title: Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation.
PubMed ID: 27105115
PubMed ID: 27436229
Title: SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability.
PubMed ID: 27436229
DOI: 10.1038/ncomms12235
PubMed ID: 27016736
Title: Structure and function of human histone H3.Y nucleosome.
PubMed ID: 27016736
DOI: 10.1093/nar/gkw202
PubMed ID: 28497810
Title: Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription.
PubMed ID: 28497810
DOI: 10.1038/cr.2017.68
PubMed ID: 28190768
Title: Serine ADP-ribosylation depends on HPF1.
PubMed ID: 28190768
PubMed ID: 29211711
Title: KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.
PubMed ID: 29211711
DOI: 10.1038/nature25003
PubMed ID: 30257210
Title: Interplay of histone marks with serine ADP-ribosylation.
PubMed ID: 30257210
PubMed ID: 29480802
Title: Serine is the major residue for ADP-ribosylation upon DNA damage.
PubMed ID: 29480802
DOI: 10.7554/elife.34334
PubMed ID: 31542297
Title: Glutarylation of histone H4 lysine 91 regulates chromatin dynamics.
PubMed ID: 31542297
PubMed ID: 30867594
Title: Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
PubMed ID: 30867594
PubMed ID: 31645732
Title: Metabolic regulation of gene expression by histone lactylation.
PubMed ID: 31645732
PubMed ID: 31527692
Title: VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor syndromes.
PubMed ID: 31527692
PubMed ID: 32273471
Title: Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking.
PubMed ID: 32273471
PubMed ID: 34874266
Title: Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.
PubMed ID: 34874266
DOI: 10.7554/elife.71502
PubMed ID: 35939806
Title: Potent Activation of NAD+-Dependent Deacetylase Sirt7 by Nucleosome Binding.
PubMed ID: 35939806
PubMed ID: 24590075
Title: ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.
PubMed ID: 24590075
DOI: 10.1038/nature13045
PubMed ID: 33857403
Title: DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
PubMed ID: 33857403
PubMed ID: 32911480
Title: Structural basis for sequestration and autoinhibition of cGAS by chromatin.
PubMed ID: 32911480
PubMed ID: 22286216
Title: Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
PubMed ID: 22286216
DOI: 10.1038/ng.1102
PubMed ID: 22286061
Title: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
PubMed ID: 22286061
DOI: 10.1038/nature10833
PubMed ID: 23539269
Title: Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.
PubMed ID: 23539269
PubMed ID: 23603901
Title: The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
PubMed ID: 23603901
PubMed ID: 24162739
Title: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
PubMed ID: 24162739
DOI: 10.1038/ng.2814
PubMed ID: 23539183
Title: Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
PubMed ID: 23539183
PubMed ID: 27174990
Title: Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
PubMed ID: 27174990
PubMed ID: 28067913
Title: Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.
PubMed ID: 28067913
DOI: 10.1038/ng.3757
PubMed ID: 33268356
Title: Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients.
PubMed ID: 33268356
PubMed ID: 34876591
Title: De novo variants in H3-3A and H3-3B are associated with neurodevelopmental delay, dysmorphic features, and structural brain abnormalities.
PubMed ID: 34876591
Sequence Information:
- Length: 136
- Mass: 15328
- Checksum: 5158ED279E6F9E1C
- Sequence:
MARTKQTARK STGGKAPRKQ LATKAARKSA PSTGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSAAI GALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.