Details for: HNRNPA3
Gene ID: 220988
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: HNRNPA3
Ensembl ID: ENSG00000170144
Description: heterogeneous nuclear ribonucleoprotein A3
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 119.2rCSI 79.23%PRS 3.7
-
CSI 98.43rCSI 88.89%PRS 2.74
-
CSI 97.55rCSI 78.87%PRS 3.05
-
CSI 95.82rCSI 82.96%PRS 3.48
-
CSI 91.87rCSI 72.27%PRS 3.7
-
CSI 89.93rCSI 75.38%PRS 3.75
-
CSI 88.47rCSI 73.27%PRS 3.11
-
CSI 84.93rCSI 81.76%PRS 3.25
-
CSI 83.56rCSI 69.27%PRS 2.92
-
CSI 81.88rCSI 71.91%PRS 3.48
-
CSI 81.71rCSI 71.85%PRS 2.26
-
CSI 76.8rCSI 74.06%PRS 1.33
-
CSI 76.33rCSI 53.29%PRS 3.28
-
CSI 75.91rCSI 60%PRS 2.16
-
CSI 71.38rCSI 47.57%PRS 8.84
-
CSI 71.32rCSI 89.5%PRS 3.94
-
CSI 69.48rCSI 52.2%PRS 3.2
-
CSI 68.34rCSI 71.43%PRS 3.32
-
CSI 68.16rCSI 80.05%PRS 3.81
-
CSI 67.82rCSI 52.25%PRS 2.8
-
CSI 63.83rCSI 73.06%PRS 6.49
-
CSI 61.49rCSI 87.75%PRS 3.56
-
CSI 59.97rCSI 44.97%PRS 9.45
-
CSI 59.77rCSI 59.65%PRS 2.63
-
CSI 59.4rCSI 68.6%PRS 2.85
-
CSI 58.01rCSI 60.76%PRS 2.91
-
CSI 57.36rCSI 76.65%PRS 5.96
-
CSI 56.78rCSI 65.65%PRS 2.26
-
CSI 55.17rCSI 48.97%PRS 3.12
-
CSI 54.14rCSI 55.17%PRS 4.53
-
CSI 53.43rCSI 37.15%PRS 3.65
-
CSI 52.94rCSI 55.46%PRS 3.36
-
CSI 52.74rCSI 81.49%PRS 2.93
-
CSI 52.14rCSI 75.21%PRS 4.32
-
CSI 51.54rCSI 61.87%PRS 3.11
-
CSI 51rCSI 44.34%PRS 3.83
-
CSI 49.15rCSI 33.11%PRS 3.78
-
CSI 46.16rCSI 70.6%PRS 5.1
-
CSI 44.83rCSI 39.27%PRS 4.2
-
CSI 44.77rCSI 76.7%PRS 4.16
-
CSI 43.34rCSI 59.05%PRS 2.82
-
CSI 43.34rCSI 53.61%PRS 2.74
-
CSI 41.04rCSI 56.07%PRS 3.45
-
CSI 38.82rCSI 36.69%PRS 3.25
-
CSI 38.02rCSI 54.8%PRS 5.07
-
CSI 37.72rCSI 29.24%PRS 2.96
-
CSI 35.93rCSI 38.18%PRS 5.59
-
CSI 35.93rCSI 55.21%PRS 4.54
-
CSI 35.67rCSI 29.78%PRS 10.29
-
CSI 33.56rCSI 65.28%PRS 3.18
-
CSI 33.48rCSI 42.94%PRS 3.6
-
CSI 33.35rCSI 46.34%PRS 3.29
-
CSI 33.08rCSI 47.92%PRS 4.57
-
CSI 32.63rCSI 49.83%PRS 3.13
-
CSI 31.65rCSI 42.07%PRS 3.42
-
CSI 29.77rCSI 63.37%PRS 5.09
-
CSI 29.7rCSI 59.2%PRS 5.35
-
CSI 29.1rCSI 22.01%PRS 4.36
-
CSI 28.81rCSI 82.25%PRS 5.53
-
CSI 28.71rCSI 29.08%PRS 20.67
-
CSI 28.39rCSI 36.14%PRS 3.65
-
CSI 28.25rCSI 60.08%PRS 6.19
-
CSI 28.17rCSI 81.56%PRS 3.54
-
CSI 27.9rCSI 25.74%PRS 3.15
-
CSI 27.85rCSI 66.21%PRS 4.77
-
CSI 27.22rCSI 21.17%PRS 4.51
-
CSI 27.18rCSI 33.81%PRS 3.32
-
CSI 27.15rCSI 71.48%PRS 6.13
-
CSI 25.73rCSI 70.71%PRS 5.25
-
CSI 25.72rCSI 26.46%PRS 5.11
-
CSI 25.65rCSI 99.85%PRS 5.16
-
CSI 25.07rCSI 60.32%PRS 4.92
-
CSI 24.68rCSI 44.84%PRS 4.79
-
CSI 24.24rCSI 29.38%PRS 4.84
-
CSI 24.24rCSI 65.34%PRS 4.08
-
CSI 23.65rCSI 22.74%PRS 6.81
-
CSI 23.04rCSI 81.88%PRS 10.31
-
CSI 22.97rCSI 34.66%PRS 3.05
-
CSI 22.91rCSI 64.21%PRS 4.94
-
CSI 22.87rCSI 16.99%PRS 4.65
-
CSI 22.83rCSI 35.06%PRS 3.61
-
CSI 22.49rCSI 72.17%PRS 4.78
-
CSI 22.29rCSI 79.14%PRS 5.15
-
CSI 21.97rCSI 77.09%PRS 5.67
-
CSI 21.44rCSI 38.24%PRS 5.41
-
CSI 21.44rCSI 63.93%PRS 8.57
-
CSI 21.23rCSI 12.54%PRS 4.35
-
CSI 21.12rCSI 30.93%PRS 3.69
-
CSI 21rCSI 25.36%PRS 3.59
-
CSI 20.98rCSI 26.92%PRS 3.11
-
CSI 20.95rCSI 33.78%PRS 5.07
-
CSI 20.78rCSI 25.61%PRS 10.4
-
CSI 20.17rCSI 52.41%PRS 9.8
-
CSI 19.8rCSI 35.75%PRS 9.68
-
CSI 19.08rCSI 98.51%PRS 6.23
-
CSI 19.05rCSI 18.81%PRS 13.82
-
CSI 18.78rCSI 22.06%PRS 31.03
-
CSI 18.7rCSI 19.37%PRS 3.64
-
CSI 18.63rCSI 47.31%PRS 3.19
-
CSI 18.36rCSI 40.41%PRS 4.89
-
CSI -32.8rCSI -77.8%PRS 4.2%
-
CSI -11.5rCSI -13.5%PRS 5.2%
-
CSI -10.7rCSI -8.6%PRS 5.8%
-
CSI -10.7rCSI -34.1%PRS 2.3%
-
CSI -9.1rCSI -17.1%PRS 2.5%
-
CSI -7.8rCSI -37.2%PRS 1.6%
-
CSI -6.9rCSI -16.6%PRS 4.1%
-
CSI -6.7rCSI -8.0%PRS 1.9%
-
CSI -6.3rCSI -23.8%PRS 7.1%
-
CSI -6.3rCSI -35.6%PRS 0.9%
-
CSI -5.9rCSI -10.3%PRS 2.5%
-
CSI -5.9rCSI -28.1%PRS 5.5%
-
CSI -5.3rCSI -12.9%PRS 3.3%
-
CSI -5.1rCSI -14.6%PRS 4.3%
-
CSI -4.9rCSI -3.4%PRS 4.5%
-
CSI -4.2rCSI -17.2%PRS 9.7%
-
CSI -3.9rCSI -6.9%PRS 4.2%
-
CSI -3.5rCSI -9.3%PRS 3.7%
-
CSI -3.5rCSI -6.2%PRS 1.9%
-
CSI -3.4rCSI -4.4%PRS 4.1%
-
CSI -2.6rCSI -5.9%PRS 8.1%
-
CSI -2.5rCSI -12.8%PRS 1.9%
-
CSI -2.5rCSI -6.8%PRS 3.6%
-
CSI -2.4rCSI -4.5%PRS 5.0%
-
CSI -2.3rCSI -14.5%PRS 2.6%
-
CSI -2.3rCSI -2.9%PRS 1.8%
-
CSI -2.0rCSI -11.6%PRS 4.8%
-
CSI -1.9rCSI -11.9%PRS 16.5%
-
CSI -1.5rCSI -3.3%PRS 2.0%
-
CSI -1.4rCSI -3.6%PRS 3.8%
-
CSI -1.4rCSI -3.9%PRS 4.5%
-
CSI -1.3rCSI -25.2%PRS 26.9%
-
CSI -1.3rCSI -39.6%PRS 50.8%
-
CSI -1.1rCSI -1.1%PRS 5.0%
-
CSI -1.1rCSI -4.1%PRS 5.4%
-
CSI -1.0rCSI -2.1%PRS 1.3%
-
CSI -0.6rCSI -7.6%PRS 35.9%
-
CSI -0.5rCSI -0.8%PRS 4.1%
-
CSI -0.5rCSI -6.1%PRS 27.4%
-
CSI -0.4rCSI -1.4%PRS 5.4%
-
CSI -0.4rCSI -1.0%PRS 24.8%
-
CSI -0.3rCSI -1.8%PRS 5.0%
-
CSI -0.3rCSI -1.4%PRS 24.4%
-
CSI 0.1rCSI 0.6%PRS 0.3%
-
CSI 0.1rCSI 0.2%PRS 3.2%
-
CSI 0.1rCSI 0.3%PRS 1.7%
-
CSI 0.2rCSI 3.8%PRS 19.1%
-
CSI 0.2rCSI 0.9%PRS 5.9%
-
CSI 0.3rCSI 0.9%PRS 14.7%
-
CSI 0.3rCSI 9.2%PRS 41.1%
-
CSI 0.3rCSI 0.7%PRS 3.0%
-
CSI 0.3rCSI 1.9%PRS 12.7%
-
CSI 0.4rCSI 1.6%PRS 17.3%
-
CSI 0.4rCSI 2.1%PRS 18.6%
-
CSI 0.4rCSI 7.1%PRS 28.1%
-
CSI 0.4rCSI 0.5%PRS 2.1%
-
CSI 0.4rCSI 3.4%PRS 18.5%
-
CSI 0.5rCSI 5.0%PRS 5.5%
-
CSI 0.5rCSI 2.2%PRS 3.0%
-
CSI 0.5rCSI 5.2%PRS 30.0%
-
CSI 0.5rCSI 1.0%PRS 3.3%
-
CSI 0.6rCSI 1.2%PRS 1.1%
-
CSI 0.7rCSI 3.7%PRS 8.0%
-
CSI 0.8rCSI 2.8%PRS 16.3%
-
CSI 0.8rCSI 5.2%PRS 6.4%
-
CSI 0.8rCSI 17.5%PRS 18.7%
-
CSI 0.9rCSI 5.1%PRS 18.0%
-
CSI 0.9rCSI 2.3%PRS 5.8%
-
CSI 0.9rCSI 4.0%PRS 3.2%
-
CSI 1.0rCSI 2.3%PRS 23.0%
-
CSI 1.0rCSI 4.6%PRS 8.9%
-
CSI 1.0rCSI 2.5%PRS 4.6%
-
CSI 1.0rCSI 4.0%PRS 15.1%
-
CSI 1.0rCSI 3.4%PRS 1.5%
-
CSI 1.2rCSI 7.6%PRS 24.8%
-
CSI 1.2rCSI 16.5%PRS 2.5%
-
CSI 1.2rCSI 13.2%PRS 12.0%
-
CSI 1.3rCSI 3.3%PRS 11.6%
-
CSI 1.3rCSI 1.9%PRS 2.7%
-
CSI 1.3rCSI 4.2%PRS 3.9%
-
CSI 1.3rCSI 2.2%PRS 6.5%
-
CSI 1.4rCSI 12.7%PRS 12.4%
-
CSI 1.4rCSI 14.9%PRS 15.9%
-
CSI 1.4rCSI 7.1%PRS 15.2%
-
CSI 1.4rCSI 5.7%PRS 4.0%
-
CSI 1.5rCSI 30.9%PRS 20.4%
-
CSI 1.5rCSI 12.3%PRS 3.3%
-
CSI 1.5rCSI 2.7%PRS 3.5%
-
CSI 1.6rCSI 2.7%PRS 2.4%
-
CSI 1.6rCSI 3.7%PRS 3.0%
-
CSI 1.6rCSI 4.1%PRS 2.5%
-
CSI 1.7rCSI 11.1%PRS 15.6%
-
CSI 1.8rCSI 7.1%PRS 3.6%
-
CSI 1.8rCSI 3.5%PRS 9.2%
-
CSI 1.8rCSI 43.1%PRS 2.0%
-
CSI 1.8rCSI 2.9%PRS 8.1%
-
CSI 1.8rCSI 42.9%PRS 23.6%
-
CSI 1.8rCSI 10.3%PRS 12.1%
-
CSI 1.9rCSI 20.4%PRS 22.8%
-
CSI 1.9rCSI 14.1%PRS 1.4%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 263495746
Symbol: ROA3_HUMAN
Name: Heterogeneous nuclear ribonucleoprotein A3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11886857
Title: Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein.
PubMed ID: 11886857
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11991638
Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
PubMed ID: 11991638
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 378
- Mass: 39595
- Checksum: 832372C4C29547B1
- Sequence:
MEVKPPPGRP QPDSGRRRRR RGEEGHDPKE PEQLRKLFIG GLSFETTDDS LREHFEKWGT LTDCVVMRDP QTKRSRGFGF VTYSCVEEVD AAMCARPHKV DGRVVEPKRA VSREDSVKPG AHLTVKKIFV GGIKEDTEEY NLRDYFEKYG KIETIEVMED RQSGKKRGFA FVTFDDHDTV DKIVVQKYHT INGHNCEVKK ALSKQEMQSA GSQRGRGGGS GNFMGRGGNF GGGGGNFGRG GNFGGRGGYG GGGGGSRGSY GGGDGGYNGF GGDGGNYGGG PGYSSRGGYG GGGPGYGNQG GGYGGGGGYD GYNEGGNFGG GNYGGGGNYN DFGNYSGQQQ SNYGPMKGGS FGGRSSGSPY GGGYGSGGGS GGYGSRRF
Genular Protein ID: 2084854245
Symbol: A0A7I2V2R3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 331
- Mass: 35412
- Checksum: 4F643F1316F299CE
- Sequence:
MEVKPPPGRP QPDSGRRRRR RGEEGHDPKE PEQLRKLFIG GLSFETTDDS LREHFEKWGT LTDCVVMRDP QTKRSRGFGF VTYSCVEEVD AAMCARPHKV DGRVVEPKRA VSREDSVKPG AHLTVKKIFV GGIKEDTEEY NLRDYFEKYG KIETIEVMED RQSGKKRGFA FVTFDDHDTV DKIVVQKYHT INGHNCEVKK ALSKQEMQSA GSQRGRGGGS GNFMGRGGNF GGGGGNFGRG GNFGGRGGYG GGGGGSRGSY GGGDGGYNGF GGDGNYGGGG NYNDFGNYSG QQQSNYGPMK GGSFGGRSSG SPYGGGYGSG GGSGGYGSRR F
Genular Protein ID: 412534365
Symbol: B4DDB6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 356
- Mass: 37029
- Checksum: C2D8451FC6D6A60A
- Sequence:
MEGHDPKEPE QLRKLFIGGL SFETTDDSLR EHFEKWGTLT DCVVMRDPQT KRSRGFGFVT YSCVEEVDAA MCARPHKVDG RVVEPKRAVS REDSVKPGAH LTVKKIFVGG IKEDTEEYNL RDYFEKYGKI ETIEVMEDRQ SGKKRGFAFV TFDDHDTVDK IVVQKYHTIN GHNCEVKKAL SKQEMQSAGS QRGRGGGSGN FMGRGGNFGG GGGNFGRGGN FGGRGGYGGG GGGSRGSYGG GDGGYNGFGG DGGNYGGGPG YSSRGGYGGG GPGYGNQGGG YGGGGGYDGY NEGGNFGGGN YGGGGNYNDF GNYSGQQQSN YGPMKGGSFG GRSSGSPYGG GYGSGGGSGG YGSRRF