Cell ID: CL0000819

Cell Name: B-1 B cell

CSI Thresholds:

Select	Context	Threshold
	Overall	8.7151
	Kidney	11.4556
	Liver + Healthy	9.1273
	Liver	8.3650
	Healthy	7.0848
	Spleen	6.0324
	Spleen + Healthy	6.0117
	Skin of body + Healthy	2.3299
	Skin of body	2.2868
	Kidney + Healthy	0.5430
	Thymus	-0.9967
	Thymus + Healthy	-1.0286

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive.

Synonyms: B-1 B lymphocyte, B-1 B-cell, B-1 B-lymphocyte, B-1 cell, B1 B cell, B1 B lymphocyte, B1 B-cell, B1 B-lymphocyte, B1 cell