Details for: MCM5

Gene ID: 4174

Symbol: MCM5

Ensembl ID: ENSG00000100297

Description: minichromosome maintenance complex component 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 39.6410
    Cell Significance Index: -16.3300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 34.8548
    Cell Significance Index: -14.1600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 33.4659
    Cell Significance Index: -15.8000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 31.4550
    Cell Significance Index: -16.1800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 28.8594
    Cell Significance Index: -7.3200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 23.5462
    Cell Significance Index: -15.8000
  • Cell Name: basophilic erythroblast (CL0000549)
    Fold Change: 18.5549
    Cell Significance Index: 8.4500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.6411
    Cell Significance Index: -13.1200
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 5.4004
    Cell Significance Index: -0.8400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.2779
    Cell Significance Index: -11.4600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.2032
    Cell Significance Index: -12.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.9837
    Cell Significance Index: -15.7200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 2.4658
    Cell Significance Index: 243.9300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 2.3773
    Cell Significance Index: 63.5900
  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.3442
    Cell Significance Index: 17.7000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.0516
    Cell Significance Index: -4.4900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.9638
    Cell Significance Index: 231.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.5562
    Cell Significance Index: 296.1600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.3099
    Cell Significance Index: 14.2400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.3059
    Cell Significance Index: 78.4000
  • Cell Name: centroblast (CL0009112)
    Fold Change: 1.2773
    Cell Significance Index: 2.9800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1431
    Cell Significance Index: 185.9200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.1404
    Cell Significance Index: 39.6300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.8764
    Cell Significance Index: 23.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8200
    Cell Significance Index: 52.9000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.7406
    Cell Significance Index: 19.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4991
    Cell Significance Index: 450.6300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.4945
    Cell Significance Index: 10.3500
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.4899
    Cell Significance Index: 3.2500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4636
    Cell Significance Index: 92.0000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3654
    Cell Significance Index: 25.2700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3323
    Cell Significance Index: 146.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3241
    Cell Significance Index: 10.3800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3056
    Cell Significance Index: 8.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3010
    Cell Significance Index: 16.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1853
    Cell Significance Index: 22.7900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1797
    Cell Significance Index: 2.7800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1778
    Cell Significance Index: 97.0900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1374
    Cell Significance Index: 9.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1233
    Cell Significance Index: 16.9300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1187
    Cell Significance Index: 3.4900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.1126
    Cell Significance Index: 1.5800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0968
    Cell Significance Index: 2.7900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0824
    Cell Significance Index: 14.8600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0773
    Cell Significance Index: 0.8000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.0726
    Cell Significance Index: 0.9300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0576
    Cell Significance Index: 2.9900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0528
    Cell Significance Index: 6.8200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0406
    Cell Significance Index: 5.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0095
    Cell Significance Index: 0.4300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0013
    Cell Significance Index: 0.0600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0004
    Cell Significance Index: 0.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0015
    Cell Significance Index: -0.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0023
    Cell Significance Index: -0.0500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0024
    Cell Significance Index: -0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0044
    Cell Significance Index: -8.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0049
    Cell Significance Index: -0.5000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0090
    Cell Significance Index: -16.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0105
    Cell Significance Index: -7.9700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0110
    Cell Significance Index: -16.9600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0134
    Cell Significance Index: -0.4700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0142
    Cell Significance Index: -19.2700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0143
    Cell Significance Index: -10.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0194
    Cell Significance Index: -12.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0237
    Cell Significance Index: -17.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0282
    Cell Significance Index: -17.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0300
    Cell Significance Index: -13.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0301
    Cell Significance Index: -16.9900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0328
    Cell Significance Index: -11.7800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0378
    Cell Significance Index: -0.8200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0426
    Cell Significance Index: -4.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0434
    Cell Significance Index: -12.4900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0471
    Cell Significance Index: -9.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0564
    Cell Significance Index: -8.2000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0573
    Cell Significance Index: -9.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0593
    Cell Significance Index: -4.4200
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: -0.0658
    Cell Significance Index: -0.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0777
    Cell Significance Index: -8.9000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0878
    Cell Significance Index: -18.5000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0941
    Cell Significance Index: -2.5600
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.1278
    Cell Significance Index: -0.8000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1309
    Cell Significance Index: -1.0500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1369
    Cell Significance Index: -2.5300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1473
    Cell Significance Index: -15.3400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1584
    Cell Significance Index: -8.2500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1647
    Cell Significance Index: -10.1000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1668
    Cell Significance Index: -4.4700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1706
    Cell Significance Index: -10.7500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1818
    Cell Significance Index: -14.4000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1862
    Cell Significance Index: -2.5400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1918
    Cell Significance Index: -2.8900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1935
    Cell Significance Index: -14.8500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2077
    Cell Significance Index: -12.7700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2327
    Cell Significance Index: -12.2200
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.2334
    Cell Significance Index: -1.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2394
    Cell Significance Index: -16.1000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2682
    Cell Significance Index: -10.9900
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.2954
    Cell Significance Index: -4.1400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.2974
    Cell Significance Index: -1.7700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3037
    Cell Significance Index: -15.3500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **MCM Complex Subunit:** MCM5 is a subunit of the MCM complex, a heteropentameric complex composed of five MCM proteins (MCM2-7). 2. **DNA Replication:** MCM5 is essential for the assembly and activation of the pre-replicative complex, which is a critical step in DNA replication initiation. 3. **Cell Cycle Regulation:** MCM5 is involved in regulating the G1/S transition and G2/M checkpoints, ensuring proper cell cycle progression. 4. **DNA Unwinding:** MCM5 participates in DNA strand elongation and unwinding during replication, facilitating the synthesis of new DNA strands. 5. **Expression in Various Cell Types:** MCM5 is expressed in early promyelocytes, placental villous trophoblasts, and germinal center B cells, indicating its importance in different cellular contexts. **Pathways and Functions:** 1. **DNA Replication Initiation:** MCM5 is involved in the assembly and activation of the pre-replicative complex, which is a critical step in DNA replication initiation. 2. **Cell Cycle Regulation:** MCM5 regulates the G1/S transition and G2/M checkpoints, ensuring proper cell cycle progression. 3. **DNA Strand Elongation:** MCM5 participates in DNA strand elongation and unwinding during replication, facilitating the synthesis of new DNA strands. 4. **3'-5' DNA Helicase Activity:** MCM5 exhibits 3'-5' DNA helicase activity, which is essential for DNA replication and repair. 5. **Regulation of DNA-templated DNA Replication Initiation:** MCM5 regulates the initiation of DNA replication, ensuring accurate and efficient DNA synthesis. **Clinical Significance:** 1. **Cancer Association:** Dysregulation of MCM5 has been implicated in various cancers, including breast, lung, and colon cancers. 2. **Genomic Instability:** MCM5 plays a critical role in maintaining genome stability, and dysregulation can lead to genomic instability and cancer. 3. **Reproductive Implications:** MCM5 is essential for oogenesis and spermatogenesis, and dysregulation can lead to reproductive abnormalities. 4. **Infectious Diseases:** MCM5 may play a role in the replication of certain viruses, such as HIV, highlighting its importance in immune function and disease susceptibility. 5. **Therapeutic Target:** MCM5 may serve as a therapeutic target for the treatment of various diseases, including cancer and infectious diseases. In conclusion, the MCM5 gene plays a critical role in DNA replication and cell cycle regulation, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the mechanisms of MCM5 and its role in human health and disease.

Genular Protein ID: 3491625353

Symbol: MCM5_HUMAN

Name: N/A

UniProtKB Accession Codes:

P33992 O60785 Q14578 Q9BTJ4 Q9BWL8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 7 EMDB 6 Ensembl 1 ExpressionAtlas 1 GO 16 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 Rhea 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8265339

Title: The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins.

PubMed ID: 8265339

DOI: 10.1093/nar/21.23.5289-a

PubMed ID: 16899510

Title: Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells.

PubMed ID: 16899510

DOI: 10.1091/mbc.e06-03-0241

PubMed ID: 17296731

Title: Identification and characterization of a novel component of the human minichromosome maintenance complex.

PubMed ID: 17296731

DOI: 10.1128/mcb.02384-06

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23711367

Title: A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses.

PubMed ID: 23711367

DOI: 10.1016/j.febslet.2013.05.037

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26527279

Title: Analysis of the histone H3.1 interactome: a suitable chaperone for the right event.

PubMed ID: 26527279

DOI: 10.1016/j.molcel.2015.08.005

PubMed ID: 35585232

Title: Fast and efficient DNA replication with purified human proteins.

PubMed ID: 35585232

DOI: 10.1038/s41586-022-04759-1

PubMed ID: 32453425

Title: CryoEM structures of human CMG-ATPgammaS-DNA and CMG-AND-1 complexes.

PubMed ID: 32453425

DOI: 10.1093/nar/gkaa429

PubMed ID: 34700328

Title: A conserved mechanism for regulating replisome disassembly in eukaryotes.

PubMed ID: 34700328

DOI: 10.1038/s41586-021-04145-3

PubMed ID: 34694004

Title: Structure of a human replisome shows the organisation and interactions of a DNA replication machine.

PubMed ID: 34694004

DOI: 10.15252/embj.2021108819

PubMed ID: 28198391

Title: MCM5: a new actor in the link between DNA replication and Meier-Gorlin syndrome.

PubMed ID: 28198391

DOI: 10.1038/ejhg.2017.5

Sequence Information:

  • Length: 734
  • Mass: 82286
  • Checksum: A80280E61749998D
  • Sequence:
    • MSGFDDPGIF YSDSFGGDAQ ADEGQARKSQ LQRRFKEFLR QYRVGTDRTG FTFKYRDELK 
RHYNLGEYWI EVEMEDLASF DEDLADYLYK QPAEHLQLLE EAAKEVADEV TRPRPSGEEV 
LQDIQVMLKS DASPSSIRSL KSDMMSHLVK IPGIIIAASA VRAKATRISI QCRSCRNTLT 
NIAMRPGLEG YALPRKCNTD QAGRPKCPLD PYFIMPDKCK CVDFQTLKLQ ELPDAVPHGE 
MPRHMQLYCD RYLCDKVVPG NRVTIMGIYS IKKFGLTTSR GRDRVGVGIR SSYIRVLGIQ 
VDTDGSGRSF AGAVSPQEEE EFRRLAALPN VYEVISKSIA PSIFGGTDMK KAIACLLFGG 
SRKRLPDGLT RRGDINLLML GDPGTAKSQL LKFVEKCSPI GVYTSGKGSS AAGLTASVMR 
DPSSRNFIME GGAMVLADGG VVCIDEFDKM REDDRVAIHE AMEQQTISIA KAGITTTLNS 
RCSVLAAANS VFGRWDETKG EDNIDFMPTI LSRFDMIFIV KDEHNEERDV MLAKHVITLH 
VSALTQTQAV EGEIDLAKLK KFIAYCRVKC GPRLSAEAAE KLKNRYIIMR SGARQHERDS 
DRRSSIPITV RQLEAIVRIA EALSKMKLQP FATEADVEEA LRLFQVSTLD AALSGTLSGV 
EGFTSQEDQE MLSRIEKQLK RRFAIGSQVS EHSIIKDFTK QKYPEHAIHK VLQLMLRRGE 
IQHRMQRKVL YRLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.