Details for: CL0002563

Cell ID: CL0002563

Cell Name: intestinal epithelial cell

Marker Score Threshold: 1,624
(Derived using integrated single-cell and genomic data)

Description: An epithelial cell of the intestine.

Genes (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Gene Symbol: MALAT1 (ENSG00000251562)
    Fold Change: 11.38
    Ensembl ID: ENSG00000251562
  • Gene Symbol: RNU1 14P (ENSG00000199629)
    Fold Change: 2.52
    Ensembl ID: ENSG00000199629
  • Gene Symbol: TTTY5 (ENSG00000215560)
    Fold Change: 2.52
    Ensembl ID: ENSG00000215560
  • Gene Symbol: CSPG4P1Y (ENSG00000240450)
    Fold Change: 2.52
    Ensembl ID: ENSG00000240450
  • Gene Symbol: TTTY20 (ENSG00000232808)
    Fold Change: 2.52
    Ensembl ID: ENSG00000232808
  • Gene Symbol: TTTY3B (ENSG00000280961)
    Fold Change: 2.52
    Ensembl ID: ENSG00000280961
  • Gene Symbol: CT45A6 (ENSG00000278289)
    Fold Change: 2.52
    Ensembl ID: ENSG00000278289
  • Gene Symbol: MIR509 2 (ENSG00000212013)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212013
  • Gene Symbol: CXorf51A (ENSG00000224440)
    Fold Change: 2.52
    Ensembl ID: ENSG00000224440
  • Gene Symbol: VTRNA3 1P (ENSG00000199422)
    Fold Change: 2.52
    Ensembl ID: ENSG00000199422
  • Gene Symbol: RNU7 6P (ENSG00000252654)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252654
  • Gene Symbol: RNU7 22P (ENSG00000252482)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252482
  • Gene Symbol: RNU7 53P (ENSG00000252514)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252514
  • Gene Symbol: RNU7 66P (ENSG00000238949)
    Fold Change: 2.52
    Ensembl ID: ENSG00000238949
  • Gene Symbol: RNU7 74P (ENSG00000239010)
    Fold Change: 2.52
    Ensembl ID: ENSG00000239010
  • Gene Symbol: RNY4P14 (ENSG00000200526)
    Fold Change: 2.52
    Ensembl ID: ENSG00000200526
  • Gene Symbol: MIR4317 (ENSG00000283532)
    Fold Change: 2.52
    Ensembl ID: ENSG00000283532
  • Gene Symbol: MIR4283 1 (ENSG00000264426)
    Fold Change: 2.52
    Ensembl ID: ENSG00000264426
  • Gene Symbol: MIR3649 (ENSG00000266043)
    Fold Change: 2.52
    Ensembl ID: ENSG00000266043
  • Gene Symbol: MIR4483 (ENSG00000283656)
    Fold Change: 2.52
    Ensembl ID: ENSG00000283656
  • Gene Symbol: MIR3974 (ENSG00000283665)
    Fold Change: 2.52
    Ensembl ID: ENSG00000283665
  • Gene Symbol: MIR3977 (ENSG00000283359)
    Fold Change: 2.52
    Ensembl ID: ENSG00000283359
  • Gene Symbol: MIR4771 1 (ENSG00000264793)
    Fold Change: 2.52
    Ensembl ID: ENSG00000264793
  • Gene Symbol: RNY3P7 (ENSG00000206800)
    Fold Change: 2.52
    Ensembl ID: ENSG00000206800
  • Gene Symbol: RNY4P30 (ENSG00000222148)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222148
  • Gene Symbol: RNU4 10P (ENSG00000201253)
    Fold Change: 2.52
    Ensembl ID: ENSG00000201253
  • Gene Symbol: RNA5SP18 (ENSG00000212237)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212237
  • Gene Symbol: RNA5SP45 (ENSG00000252563)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252563
  • Gene Symbol: RNA5SP121 (ENSG00000252346)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252346
  • Gene Symbol: RNA5SP136 (ENSG00000222838)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222838
  • Gene Symbol: RNA5SP225 (ENSG00000222806)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222806
  • Gene Symbol: RNA5SP231 (ENSG00000222428)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222428
  • Gene Symbol: RNA5SP281 (ENSG00000252313)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252313
  • Gene Symbol: RNA5SP286 (ENSG00000212454)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212454
  • Gene Symbol: RNA5SP287 (ENSG00000252167)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252167
  • Gene Symbol: RNA5SP502 (ENSG00000199564)
    Fold Change: 2.52
    Ensembl ID: ENSG00000199564
  • Gene Symbol: RNA5SP507 (ENSG00000200473)
    Fold Change: 2.52
    Ensembl ID: ENSG00000200473
  • Gene Symbol: RNA5SP299 (ENSG00000212505)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212505
  • Gene Symbol: RNA5SP329 (ENSG00000202147)
    Fold Change: 2.52
    Ensembl ID: ENSG00000202147
  • Gene Symbol: RNA5SP353 (ENSG00000201476)
    Fold Change: 2.52
    Ensembl ID: ENSG00000201476
  • Gene Symbol: RNA5SP359 (ENSG00000201708)
    Fold Change: 2.52
    Ensembl ID: ENSG00000201708
  • Gene Symbol: RNA5SP369 (ENSG00000223046)
    Fold Change: 2.52
    Ensembl ID: ENSG00000223046
  • Gene Symbol: RNA5SP382 (ENSG00000200225)
    Fold Change: 2.52
    Ensembl ID: ENSG00000200225
  • Gene Symbol: RNA5SP428 (ENSG00000201999)
    Fold Change: 2.52
    Ensembl ID: ENSG00000201999
  • Gene Symbol: RNA5SP441 (ENSG00000252618)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252618
  • Gene Symbol: RNA5SP451 (ENSG00000222520)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222520
  • Gene Symbol: RNA5SP481 (ENSG00000252623)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252623
  • Gene Symbol: RNU6 63P (ENSG00000252499)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252499
  • Gene Symbol: RNU6 66P (ENSG00000200267)
    Fold Change: 2.52
    Ensembl ID: ENSG00000200267
  • Gene Symbol: RNU6 71P (ENSG00000207203)
    Fold Change: 2.52
    Ensembl ID: ENSG00000207203
  • Gene Symbol: RNY1P7 (ENSG00000207474)
    Fold Change: 2.52
    Ensembl ID: ENSG00000207474
  • Gene Symbol: RNY1P8 (ENSG00000206697)
    Fold Change: 2.52
    Ensembl ID: ENSG00000206697
  • Gene Symbol: RNY3P4 (ENSG00000207157)
    Fold Change: 2.52
    Ensembl ID: ENSG00000207157
  • Gene Symbol: RNY4P28 (ENSG00000202151)
    Fold Change: 2.52
    Ensembl ID: ENSG00000202151
  • Gene Symbol: RNU5F 6P (ENSG00000199849)
    Fold Change: 2.52
    Ensembl ID: ENSG00000199849
  • Gene Symbol: RNU5F 7P (ENSG00000200566)
    Fold Change: 2.52
    Ensembl ID: ENSG00000200566
  • Gene Symbol: RNU5E 7P (ENSG00000202160)
    Fold Change: 2.52
    Ensembl ID: ENSG00000202160
  • Gene Symbol: PLSCR5 AS1 (ENSG00000241457)
    Fold Change: 2.52
    Ensembl ID: ENSG00000241457
  • Gene Symbol: MIR6862 2 (ENSG00000278340)
    Fold Change: 2.52
    Ensembl ID: ENSG00000278340
  • Gene Symbol: MIR8071 2 (ENSG00000277030)
    Fold Change: 2.52
    Ensembl ID: ENSG00000277030
  • Gene Symbol: RNU6 22P (ENSG00000207083)
    Fold Change: 2.52
    Ensembl ID: ENSG00000207083
  • Gene Symbol: RNA5SP130 (ENSG00000201301)
    Fold Change: 2.52
    Ensembl ID: ENSG00000201301
  • Gene Symbol: RNU7 164P (ENSG00000238730)
    Fold Change: 2.52
    Ensembl ID: ENSG00000238730
  • Gene Symbol: RNU7 167P (ENSG00000238584)
    Fold Change: 2.52
    Ensembl ID: ENSG00000238584
  • Gene Symbol: RN7SKP44 (ENSG00000200472)
    Fold Change: 2.52
    Ensembl ID: ENSG00000200472
  • Gene Symbol: RN7SKP59 (ENSG00000222452)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222452
  • Gene Symbol: RN7SKP155 (ENSG00000251840)
    Fold Change: 2.52
    Ensembl ID: ENSG00000251840
  • Gene Symbol: RN7SKP262 (ENSG00000222950)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222950
  • Gene Symbol: RN7SKP289 (ENSG00000253053)
    Fold Change: 2.52
    Ensembl ID: ENSG00000253053
  • Gene Symbol: RN7SL87P (ENSG00000239390)
    Fold Change: 2.52
    Ensembl ID: ENSG00000239390
  • Gene Symbol: RN7SL140P (ENSG00000266059)
    Fold Change: 2.52
    Ensembl ID: ENSG00000266059
  • Gene Symbol: RN7SL147P (ENSG00000263988)
    Fold Change: 2.52
    Ensembl ID: ENSG00000263988
  • Gene Symbol: RN7SL191P (ENSG00000241198)
    Fold Change: 2.52
    Ensembl ID: ENSG00000241198
  • Gene Symbol: RN7SL214P (ENSG00000242066)
    Fold Change: 2.52
    Ensembl ID: ENSG00000242066
  • Gene Symbol: RN7SL248P (ENSG00000274186)
    Fold Change: 2.52
    Ensembl ID: ENSG00000274186
  • Gene Symbol: RN7SL271P (ENSG00000239250)
    Fold Change: 2.52
    Ensembl ID: ENSG00000239250
  • Gene Symbol: RN7SL361P (ENSG00000242158)
    Fold Change: 2.52
    Ensembl ID: ENSG00000242158
  • Gene Symbol: RN7SL564P (ENSG00000240606)
    Fold Change: 2.52
    Ensembl ID: ENSG00000240606
  • Gene Symbol: RN7SL647P (ENSG00000243957)
    Fold Change: 2.52
    Ensembl ID: ENSG00000243957
  • Gene Symbol: RN7SL722P (ENSG00000273940)
    Fold Change: 2.52
    Ensembl ID: ENSG00000273940
  • Gene Symbol: RN7SL759P (ENSG00000278497)
    Fold Change: 2.52
    Ensembl ID: ENSG00000278497
  • Gene Symbol: RNU4ATAC4P (ENSG00000252116)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252116
  • Gene Symbol: RNU4ATAC6P (ENSG00000252401)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252401
  • Gene Symbol: RNU6ATAC21P (ENSG00000221583)
    Fold Change: 2.52
    Ensembl ID: ENSG00000221583
  • Gene Symbol: RNU6ATAC28P (ENSG00000238561)
    Fold Change: 2.52
    Ensembl ID: ENSG00000238561
  • Gene Symbol: RNU6ATAC40P (ENSG00000221507)
    Fold Change: 2.52
    Ensembl ID: ENSG00000221507
  • Gene Symbol: RNU4 30P (ENSG00000222177)
    Fold Change: 2.52
    Ensembl ID: ENSG00000222177
  • Gene Symbol: RNU6 113P (ENSG00000252462)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252462
  • Gene Symbol: RNU6 120P (ENSG00000251886)
    Fold Change: 2.52
    Ensembl ID: ENSG00000251886
  • Gene Symbol: RNU6 131P (ENSG00000212446)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212446
  • Gene Symbol: RNU6 148P (ENSG00000252823)
    Fold Change: 2.52
    Ensembl ID: ENSG00000252823
  • Gene Symbol: RNU6 163P (ENSG00000207124)
    Fold Change: 2.52
    Ensembl ID: ENSG00000207124
  • Gene Symbol: RNU6 214P (ENSG00000206857)
    Fold Change: 2.52
    Ensembl ID: ENSG00000206857
  • Gene Symbol: RNU6 219P (ENSG00000201598)
    Fold Change: 2.52
    Ensembl ID: ENSG00000201598
  • Gene Symbol: RNU6 225P (ENSG00000207343)
    Fold Change: 2.52
    Ensembl ID: ENSG00000207343
  • Gene Symbol: RNU6 241P (ENSG00000212450)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212450
  • Gene Symbol: RNU6 279P (ENSG00000212599)
    Fold Change: 2.52
    Ensembl ID: ENSG00000212599
  • Gene Symbol: RNU6 369P (ENSG00000199385)
    Fold Change: 2.52
    Ensembl ID: ENSG00000199385
  • Gene Symbol: RNU6 413P (ENSG00000206842)
    Fold Change: 2.52
    Ensembl ID: ENSG00000206842
  • Gene Symbol: RNU6 470P (ENSG00000251763)
    Fold Change: 2.52
    Ensembl ID: ENSG00000251763

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in intestinal epithelial cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in intestinal epithelial cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.
**Key Characteristics** Intestinal epithelial cells are characterized by several key features, including: * **Location**: IECs line the intestinal tract, from the stomach to the rectum. * **Function**: IECs are responsible for the absorption of nutrients, secretion of ions and enzymes, and maintenance of the intestinal barrier function. * **Cellular structure**: IECs are polyhedral cells with a large surface area, featuring microvilli and tight junctions. * **Gene expression**: IECs express a unique set of genes, including lncRNAs, miRNAs, and other regulatory elements that influence their behavior. * **Regulatory mechanisms**: IECs are regulated by various signaling pathways, including the hypoxia-inducible factor (HIF) pathway, which is involved in the response to hypoxia. **Gene Expression Profile** The intestinal epithelial cell CL0002563 expresses a range of genes, including: * **MALAT1**: a long non-coding RNA that regulates gene expression and is involved in the response to hypoxia. * **RNU1 14P**: a microRNA that regulates cell motility and mirna catabolic process. * **TTY5**: a long non-coding RNA that regulates cell motility and mirna catabolic process. * **CSPG4P1Y**: a long non-coding RNA that regulates cell motility and mirna catabolic process. * **TTY20**: a long non-coding RNA that regulates cell motility and mirna catabolic process. * **TTY3B**: a long non-coding RNA that regulates cell motility and mirna catabolic process. * **CT45A6**: a long non-coding RNA that regulates cardiac muscle myoblast proliferation. * **MIR509 2**: a microRNA that regulates mirna catabolic process. * **CXorf51A**: a long non-coding RNA that regulates positive regulation of cardiac muscle myoblast proliferation. * **VTRNA3 1P**: a long non-coding RNA that regulates positive regulation of cardiac muscle myoblast proliferation. **Clinical Significance** Intestinal epithelial cells play a crucial role in maintaining the integrity of the intestinal barrier function, which is essential for the prevention of infection and disease. The specific cell CL0002563 has been implicated in various diseases, including: * **Inflammatory bowel disease (IBD)**: IECs are thought to play a key role in the development of IBD, and alterations in gene expression and function have been observed in patients with IBD. * **Cancer**: IECs have been implicated in the development and progression of colorectal cancer, and alterations in gene expression and function have been observed in cancer cells. * **Gastrointestinal motility disorders**: IECs are thought to play a key role in regulating gastrointestinal motility, and alterations in gene expression and function have been observed in patients with gastrointestinal motility disorders. Overall, the intestinal epithelial cell CL0002563 is a complex cell type that plays a crucial role in maintaining the integrity of the intestinal barrier function and regulating various cellular processes. Further research is needed to fully understand the role of this cell type in disease and to develop effective therapeutic strategies.