Details for: SHBG

Gene ID: 6462

Symbol: SHBG

Ensembl ID: ENSG00000129214

Description: sex hormone binding globulin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 13.9172
    Cell Significance Index: -3.5300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.2684
    Cell Significance Index: 11.6800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.8499
    Cell Significance Index: -1.8600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.7073
    Cell Significance Index: 43.3700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.4383
    Cell Significance Index: 11.7500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.4227
    Cell Significance Index: 7.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3445
    Cell Significance Index: 34.0800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3212
    Cell Significance Index: 61.1300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2921
    Cell Significance Index: 52.6700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2725
    Cell Significance Index: 16.3600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2411
    Cell Significance Index: 47.8400
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.1880
    Cell Significance Index: 2.7300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1836
    Cell Significance Index: 3.9100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1763
    Cell Significance Index: 2.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1517
    Cell Significance Index: 7.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1138
    Cell Significance Index: 3.2800
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.1016
    Cell Significance Index: 1.4100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0988
    Cell Significance Index: 2.0500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0948
    Cell Significance Index: 10.3100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0590
    Cell Significance Index: 4.0800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0427
    Cell Significance Index: 0.7200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0418
    Cell Significance Index: 6.0800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0329
    Cell Significance Index: 6.6000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0278
    Cell Significance Index: 25.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0273
    Cell Significance Index: 0.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0232
    Cell Significance Index: 1.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0202
    Cell Significance Index: 2.4800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0188
    Cell Significance Index: 0.8500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0188
    Cell Significance Index: 0.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0171
    Cell Significance Index: 1.3200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0148
    Cell Significance Index: 0.3200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0132
    Cell Significance Index: 4.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0102
    Cell Significance Index: 0.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0075
    Cell Significance Index: 0.2100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0053
    Cell Significance Index: 10.0600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0052
    Cell Significance Index: 0.1300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0047
    Cell Significance Index: 0.0800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0035
    Cell Significance Index: 0.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0028
    Cell Significance Index: 1.7700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0026
    Cell Significance Index: 3.9300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0021
    Cell Significance Index: 3.9300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0018
    Cell Significance Index: 0.9600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0003
    Cell Significance Index: 0.4800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0020
    Cell Significance Index: -0.0300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0036
    Cell Significance Index: -1.5700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0040
    Cell Significance Index: -2.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0044
    Cell Significance Index: -3.3600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0046
    Cell Significance Index: -3.4100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0048
    Cell Significance Index: -2.2000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0052
    Cell Significance Index: -1.5000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0055
    Cell Significance Index: -3.0900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0060
    Cell Significance Index: -0.7700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0068
    Cell Significance Index: -0.0700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0071
    Cell Significance Index: -0.9700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0077
    Cell Significance Index: -1.3100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0084
    Cell Significance Index: -0.3700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0098
    Cell Significance Index: -1.1200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0100
    Cell Significance Index: -1.1600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0103
    Cell Significance Index: -0.4800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0128
    Cell Significance Index: -2.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0147
    Cell Significance Index: -1.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0174
    Cell Significance Index: -3.6700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0213
    Cell Significance Index: -1.4300
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.0227
    Cell Significance Index: -0.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0238
    Cell Significance Index: -3.0800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0249
    Cell Significance Index: -0.4000
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0273
    Cell Significance Index: -0.3500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0273
    Cell Significance Index: -1.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0305
    Cell Significance Index: -3.1800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0307
    Cell Significance Index: -0.4600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0327
    Cell Significance Index: -2.0100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0374
    Cell Significance Index: -0.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0388
    Cell Significance Index: -2.8900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0423
    Cell Significance Index: -1.8700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0436
    Cell Significance Index: -3.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0449
    Cell Significance Index: -1.7000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0487
    Cell Significance Index: -0.9500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0492
    Cell Significance Index: -0.7900
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0494
    Cell Significance Index: -0.4200
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0497
    Cell Significance Index: -0.6700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0501
    Cell Significance Index: -0.7400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0506
    Cell Significance Index: -0.3000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0506
    Cell Significance Index: -1.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0511
    Cell Significance Index: -2.4000
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0536
    Cell Significance Index: -0.4100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0575
    Cell Significance Index: -3.0200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0580
    Cell Significance Index: -1.4900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0594
    Cell Significance Index: -3.8400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0610
    Cell Significance Index: -3.1800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0619
    Cell Significance Index: -2.1700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0625
    Cell Significance Index: -1.9900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0659
    Cell Significance Index: -2.2900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0684
    Cell Significance Index: -2.1900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0690
    Cell Significance Index: -1.9700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0693
    Cell Significance Index: -1.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0716
    Cell Significance Index: -2.3500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0801
    Cell Significance Index: -2.1400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0866
    Cell Significance Index: -1.4500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0869
    Cell Significance Index: -1.8200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0896
    Cell Significance Index: -2.8400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SHBG is a glycoprotein with a molecular weight of approximately 58 kDa, composed of two identical subunits. It is primarily produced by the liver and secreted into the bloodstream, where it binds to sex hormones, such as testosterone and estradiol, thereby regulating their availability and effects on target tissues. SHBG also interacts with other proteins, including androgen receptors, insulin-like growth factor-1 (IGF-1), and growth factor receptors, modulating their activity and signaling pathways. **Pathways and Functions:** SHBG is involved in several key pathways, including: 1. **Androgen binding:** SHBG binds to androgens, such as testosterone and dihydrotestosterone, regulating their activity and availability for target tissues, including immune cells. 2. **Extracellular exosome:** SHBG is secreted into exosomes, which are small vesicles that carry proteins, lipids, and nucleic acids, influencing intercellular communication and immune responses. 3. **Protein binding:** SHBG interacts with various proteins, including growth factors, cytokines, and receptors, modulating their activity and signaling pathways. 4. **Steroid binding:** SHBG binds to sex hormones, regulating their availability and effects on target tissues. SHBG's functions include: * Regulating immune cell function and inflammation * Modulating the activity of growth factors and cytokines * Influencing cell signaling pathways, including those involved in cell growth, differentiation, and survival * Regulating the availability and effects of sex hormones on target tissues **Clinical Significance:** SHBG's dysregulation has been implicated in various diseases, including: 1. **Hypogonadism:** SHBG levels are often decreased in men with hypogonadism, leading to reduced testosterone availability and decreased libido. 2. **Polycystic ovary syndrome (PCOS):** SHBG levels are often elevated in women with PCOS, contributing to insulin resistance and metabolic dysregulation. 3. **Autoimmune diseases:** SHBG's role in regulating immune cell function and inflammation makes it a potential target for therapeutic interventions in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 4. **Cancer:** SHBG's interaction with growth factors and cytokines may influence tumor growth and metastasis, making it a potential biomarker for cancer diagnosis and prognosis. In conclusion, SHBG is a multifaceted protein that plays a crucial role in regulating immune responses, steroid metabolism, and cell signaling. Its dysregulation has significant clinical implications, making it an important area of research for the development of novel therapeutic interventions.

Genular Protein ID: 3306835218

Symbol: SHBG_HUMAN

Name: Sex steroid-binding protein

UniProtKB Accession Codes:

P04278 B0FWH4 B4DYU0 E9PGW1 F5H5Z8 I3L1N7 P14689 Q16616 Q3MIL0 Q6ISD2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 69 DrugCentral 1 EMBL 14 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 4 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 RNAct 1 RefSeq 8 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2587256

Title: Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis.

PubMed ID: 2587256

DOI: 10.1093/nar/17.22.9245

PubMed ID: 2608061

Title: The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs.

PubMed ID: 2608061

DOI: 10.1210/mend-3-11-1869

PubMed ID: 15028279

Title: PCR isolation and cloning of novel splice variant mRNAs from known drug target genes.

PubMed ID: 15028279

DOI: 10.1016/j.ygeno.2003.09.023

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3569533

Title: The cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain.

PubMed ID: 3569533

DOI: 10.1016/0014-5793(87)80121-7

PubMed ID: 2956126

Title: A cDNA coding for human sex hormone binding globulin. Homology to vitamin K-dependent protein S.

PubMed ID: 2956126

DOI: 10.1016/0014-5793(87)80890-6

PubMed ID: 2956125

Title: Characterization of a cDNA coding for sex steroid-binding protein of human plasma.

PubMed ID: 2956125

DOI: 10.1016/0014-5793(87)80261-2

PubMed ID: 3702459

Title: Physicochemical characteristics of human sex hormone binding globulin: evidence for two identical subunits.

PubMed ID: 3702459

DOI: 10.1016/0022-4731(86)90442-5

PubMed ID: 3542030

Title: Amino acid sequence of the sex steroid binding protein of human blood plasma.

PubMed ID: 3542030

DOI: 10.1021/bi00371a048

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 1400872

Title: Molecular analyses of a human sex hormone-binding globulin variant: evidence for an additional carbohydrate chain.

PubMed ID: 1400872

DOI: 10.1210/jcem.75.4.1400872

PubMed ID: 10675319

Title: Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.

PubMed ID: 10675319

DOI: 10.1093/emboj/19.4.504

PubMed ID: 12065592

Title: Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation.

PubMed ID: 12065592

DOI: 10.1074/jbc.m203999200

PubMed ID: 7714097

Title: Molecular characterization of a genetic variant of the steroid hormone-binding globulin gene in heterozygous subjects.

PubMed ID: 7714097

DOI: 10.1210/jcem.80.4.7714097

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

Sequence Information:

  • Length: 402
  • Mass: 43779
  • Checksum: 5A3B1885E4E7A460
  • Sequence:
    • MESRGPLATS RLLLLLLLLL LRHTRQGWAL RPVLPTQSAH DPPAVHLSNG PGQEPIAVMT 
FDLTKITKTS SSFEVRTWDP EGVIFYGDTN PKDDWFMLGL RDGRPEIQLH NHWAQLTVGA 
GPRLDDGRWH QVEVKMEGDS VLLEVDGEEV LRLRQVSGPL TSKRHPIMRI ALGGLLFPAS 
NLRLPLVPAL DGCLRRDSWL DKQAEISASA PTSLRSCDVE SNPGIFLPPG TQAEFNLRDI 
PQPHAEPWAF SLDLGLKQAA GSGHLLALGT PENPSWLSLH LQDQKVVLSS GSGPGLDLPL 
VLGLPLQLKL SMSRVVLSQG SKMKALALPP LGLAPLLNLW AKPQGRLFLG ALPGEDSSTS 
FCLNGLWAQG QRLDVDQALN RSHEIWTHSC PQSPGNGTDA SH

Genular Protein ID: 1762254303

Symbol: I3L145_HUMAN

Name: N/A

UniProtKB Accession Codes:

I3L145

Database IDs:

ARBA 12 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 3 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 2 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 344
  • Mass: 37488
  • Checksum: 30087AA6D4E2BCD4
  • Sequence:
    • MTFDLTKITK TSSSFEVRTW DPEGVIFYGD TNPKDDWFML GLRDGRPEIQ LHNHWAQLTV 
GAGPRLDDGR WHQVEVKMEG DSVLLEVDGE EVLRLRQVSG PLTSKRHPIM RIALGGLLFP 
ASNLRLPLVP ALDGCLRRDS WLDKQAEISA SAPTSLRSCD VESNPGIFLP PGTQAEFNLR 
DIPQPHAEPW AFSLDLGLKQ AAGSGHLLAL GTPENPSWLS LHLQDQKVVL SSGSGPGLDL 
PLVLGLPLQL KLSMSRVVLS QGSKMKALAL PPLGLAPLLN LWAKPQGRLF LGALPGEDSS 
TSFCLNGLWA QGQRLDVDQA LNRSHEIWTH SCPQSPGNGT DASH

Genular Protein ID: 1666549518

Symbol: B0FWH8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0FWH8

Database IDs:

BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 NCBI Taxonomy 1 RefSeq 1

Sequence Information:

  • Length: 10
  • Mass: 1079
  • Checksum: D0ED0CB735B33AB6
  • Sequence:
    • MAQDKSLSLS

Genular Protein ID: 4062811208

Symbol: B0FWH2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0FWH2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 RefSeq 5 SAM 1

Sequence Information:

  • Length: 37
  • Mass: 4234
  • Checksum: 32D1DBD78AAE4F4D
  • Sequence:
    • MESRGPLATS RLLLLLLLLL LRHTRQGWAL RPVLPTQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.