Details for: EEF1D

Gene ID: 1936

Symbol: EEF1D

Ensembl ID: ENSG00000104529

Description: eukaryotic translation elongation factor 1 delta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 879.8888
    Cell Significance Index: -136.8600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 509.3766
    Cell Significance Index: -129.2000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 458.2257
    Cell Significance Index: -188.7700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 391.1907
    Cell Significance Index: -184.6900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 374.7191
    Cell Significance Index: -192.7500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 276.9655
    Cell Significance Index: -185.8500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 134.4128
    Cell Significance Index: -165.7300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 47.5670
    Cell Significance Index: -146.1000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 46.0917
    Cell Significance Index: -181.8800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 25.6832
    Cell Significance Index: -56.2100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.7330
    Cell Significance Index: -34.1100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 9.2233
    Cell Significance Index: 430.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 8.2274
    Cell Significance Index: 386.6800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 8.0909
    Cell Significance Index: 212.7500
  • Cell Name: theca cell (CL0000503)
    Fold Change: 6.9566
    Cell Significance Index: 40.8700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 6.4970
    Cell Significance Index: 114.8100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 6.2926
    Cell Significance Index: 171.2800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 5.8309
    Cell Significance Index: 753.3200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 5.8136
    Cell Significance Index: 798.3700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 5.7379
    Cell Significance Index: 164.4800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 5.4012
    Cell Significance Index: 402.5500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 5.2998
    Cell Significance Index: 651.6600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 5.1341
    Cell Significance Index: 107.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 5.0802
    Cell Significance Index: 915.8000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 4.9523
    Cell Significance Index: 56.2600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 4.8295
    Cell Significance Index: 569.5500
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 4.6976
    Cell Significance Index: 28.9100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.5499
    Cell Significance Index: 2484.8200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 4.5389
    Cell Significance Index: 321.0100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 4.4847
    Cell Significance Index: 765.7800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.4818
    Cell Significance Index: 82.8400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 4.4058
    Cell Significance Index: 1947.9100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 4.0518
    Cell Significance Index: 261.4000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.0100
    Cell Significance Index: 117.7700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 3.9857
    Cell Significance Index: 43.3300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 3.3909
    Cell Significance Index: 434.6900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 3.3897
    Cell Significance Index: 117.7900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.2561
    Cell Significance Index: 41.7000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.4809
    Cell Significance Index: 492.3400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 2.3919
    Cell Significance Index: 55.2600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.9759
    Cell Significance Index: 118.6200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0415
    Cell Significance Index: 940.3700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.9926
    Cell Significance Index: 26.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9050
    Cell Significance Index: 89.5300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8399
    Cell Significance Index: 43.6300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7813
    Cell Significance Index: 7.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.7775
    Cell Significance Index: 588.5400
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.7270
    Cell Significance Index: 10.3300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3593
    Cell Significance Index: 68.3800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3521
    Cell Significance Index: 9.8400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1987
    Cell Significance Index: 3.3300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1869
    Cell Significance Index: 137.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1826
    Cell Significance Index: 8.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1568
    Cell Significance Index: 56.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1560
    Cell Significance Index: 8.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0558
    Cell Significance Index: 11.2000
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 0.0089
    Cell Significance Index: 0.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0252
    Cell Significance Index: -47.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0371
    Cell Significance Index: -3.7900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0886
    Cell Significance Index: -65.6000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.1005
    Cell Significance Index: -185.3000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.1100
    Cell Significance Index: -169.4000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1450
    Cell Significance Index: -7.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1491
    Cell Significance Index: -202.7100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1924
    Cell Significance Index: -122.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2194
    Cell Significance Index: -123.7600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2327
    Cell Significance Index: -145.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.3484
    Cell Significance Index: -158.1400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.4216
    Cell Significance Index: -68.5800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4780
    Cell Significance Index: -16.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.5335
    Cell Significance Index: -112.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.5654
    Cell Significance Index: -162.6900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.6275
    Cell Significance Index: -25.7100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.8118
    Cell Significance Index: -20.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.9170
    Cell Significance Index: -133.3000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.9332
    Cell Significance Index: -64.5400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.9548
    Cell Significance Index: -16.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.9771
    Cell Significance Index: -111.9400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.1171
    Cell Significance Index: -130.1800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.1649
    Cell Significance Index: -29.1200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.2631
    Cell Significance Index: -144.1800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.3112
    Cell Significance Index: -103.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4072
    Cell Significance Index: -45.0700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.4347
    Cell Significance Index: -110.1000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.6069
    Cell Significance Index: -12.8300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.7109
    Cell Significance Index: -178.1500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.8946
    Cell Significance Index: -119.4100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -2.0212
    Cell Significance Index: -113.4200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -2.4473
    Cell Significance Index: -33.3900
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -2.6405
    Cell Significance Index: -22.6900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.7790
    Cell Significance Index: -170.3800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -2.8452
    Cell Significance Index: -61.6400
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -3.2057
    Cell Significance Index: -17.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -3.2549
    Cell Significance Index: -93.7800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -3.7811
    Cell Significance Index: -111.3700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -3.8664
    Cell Significance Index: -23.3600
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -3.9589
    Cell Significance Index: -55.4900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -3.9836
    Cell Significance Index: -59.6900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -4.0994
    Cell Significance Index: -109.8500
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -4.1194
    Cell Significance Index: -19.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EEF1D is a conserved protein that belongs to the elongation factor 1 family, which includes eEF1E1 and eEF1A. The EEF1D protein is predominantly localized in the cytosol and is involved in the translation elongation process, where it interacts with ribosomes and transfer RNA (tRNA) to facilitate the incorporation of amino acids into the growing polypeptide chain. EEF1D exhibits guanyl-nucleotide exchange factor (GEF) activity, allowing it to exchange GDP for GTP, which is essential for its function in protein synthesis. **Pathways and Functions:** EEF1D is integrated into several signaling pathways that regulate cellular processes, including: 1. **Translation elongation:** EEF1D is a critical component of the eEF1E1 complex, which plays a central role in the translation elongation process. It facilitates the interaction between ribosomes and tRNA, ensuring the accurate incorporation of amino acids into the polypeptide chain. 2. **Cellular response to stress:** EEF1D is involved in the cellular response to stress, including heat shock and oxidative stress. It helps to regulate the translation of stress-related proteins, which are essential for cell survival. 3. **Cell signaling:** EEF1D interacts with various signaling molecules, including cadherins and integrins, to regulate cell adhesion and migration. 4. **Metabolism:** EEF1D is involved in the regulation of protein metabolism, including the translation of mRNAs into proteins and the degradation of misfolded proteins. **Clinical Significance:** EEF1D has been implicated in various diseases, including: 1. **Cancer:** EEF1D is overexpressed in several types of cancer, including breast cancer, lung cancer, and melanoma. It is thought to contribute to tumorigenesis by promoting cell proliferation and survival. 2. **Neurodegenerative diseases:** EEF1D has been linked to neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. It is thought to play a role in the regulation of protein synthesis and aggregation in these diseases. 3. **Immune disorders:** EEF1D is involved in the regulation of immune responses, including the translation of cytokines and chemokines. It is thought to contribute to the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, EEF1D is a critical component of the eukaryotic translation elongation factor 1 complex, which plays a central role in protein synthesis and cellular homeostasis. Its dysregulation has been implicated in various diseases, highlighting the importance of EEF1D in maintaining cellular balance and promoting health. Further research is needed to fully elucidate the mechanisms by which EEF1D regulates protein synthesis and its role in disease pathogenesis.

Genular Protein ID: 1276742618

Symbol: EF1D_HUMAN

Name: Elongation factor 1-delta

UniProtKB Accession Codes:

P29692 B4DDU4 D3DWK3 E9PBQ9 Q4VBZ6 Q969J1 Q96I38

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 25 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRIDE 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 18 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 3 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8334168

Title: The human leucine zipper-containing guanine-nucleotide exchange protein elongation factor-1 delta.

PubMed ID: 8334168

DOI: 10.1016/0167-4781(93)90097-w

PubMed ID: 9610721

Title: Characterization of human colon cancer antigens recognized by autologous antibodies.

PubMed ID: 9610721

DOI: 10.1002/(sici)1097-0215(19980529)76:5<652::aid-ijc7>3.0.co;2-p

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8168075

Title: Elongation factor 1 delta is enhanced following exposure to ionizing radiation.

PubMed ID: 8168075

PubMed ID: 9677419

Title: Induction of acute translational response genes by homocysteine. Elongation factors-1alpha, -beta, and -delta.

PubMed ID: 9677419

DOI: 10.1074/jbc.273.31.19840

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21597468

Title: Transformation of eEF1Bdelta into heat-shock response transcription factor by alternative splicing.

PubMed ID: 21597468

DOI: 10.1038/embor.2011.82

PubMed ID: 21936567

Title: Unbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of as a substrate for CK2.

PubMed ID: 21936567

DOI: 10.1021/pr2008994

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 281
  • Mass: 31122
  • Checksum: CE778D6D5D09BD6C
  • Sequence:
    • MATNFLAHEK IWFDKFKYDD AERRFYEQMN GPVAGASRQE NGASVILRDI ARARENIQKS 
LAGSSGPGAS SGTSGDHGEL VVRIASLEVE NQSLRGVVQE LQQAISKLEA RLNVLEKSSP 
GHRATAPQTQ HVSPMRQVEP PAKKPATPAE DDEDDDIDLF GSDNEEEDKE AAQLREERLR 
QYAEKKAKKP ALVAKSSILL DVKPWDDETD MAQLEACVRS IQLDGLVWGA SKLVPVGYGI 
RKLQIQCVVE DDKVGTDLLE EEITKFEEHV QSVDIAAFNK I

Genular Protein ID: 450278617

Symbol: B2RAR6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RAR6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 2 SMART 4 SUPFAM 1

Sequence Information:

  • Length: 647
  • Mass: 71450
  • Checksum: A83FCA7085C078E1
  • Sequence:
    • MRSGKASCTL ETVWEDKHKY EEAERRFYEH EATQAAASAQ QLPAEGPAMN GPGQDDPEDA 
DEAEAPDGGS RRDPRKSQDS RKPLQKKRKR SPKSGLGPVD LALLGLSAER VWLDKSLFDQ 
AESSYRQKLA DVAAQAAWPP ALAPWGLCTH GNQVACHHVT WGIWVNKSSF DQAERAFVEW 
SQALLLAPEG SRRQGTPNTG QQVAVPDLAH QPSPPVNGQP PLGSLQALVR EVWLEKPRYD 
AAERGFYEAL FDGHPPGKVR LQERAGLAEG ARRGRRDRRG RNILGNKRAG LRRADGEAPS 
ALPYCYFLQK DAEAPWLSKP AYDSAECRHH AAEALRVAWC LEAASLSHRP GPRSGLSVSS 
LRPNRKMATN FLAHEKIWFD KFKYDDAERR FYEQMNGPVA GASRQENGAS VILRDIARAR 
ENIQKSLAGS SGPGASSGTS GDHGELVVRI ASLEVENQSL RGVVQELQQA ISKLEARLNV 
LEKSSPGHRA TAPQTQHVSP MRQVEPPAKK PATPAEDDED DDIDLFGSDN EEEDKEAAQL 
REERLRQYAE KKAKKPALVA KSSILLDVKP WDDETDMAQL EACVRSIQLD GLVWGASKLV 
PVGYGIRKLQ IQCVVEDDKV GTDLLEEEIT KFEEHVQSVD IAAFNKI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.