Details for: HNRNPU

Gene ID: 3192

Symbol: HNRNPU

Ensembl ID: ENSG00000153187

Description: heterogeneous nuclear ribonucleoprotein U

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 5.91
    Marker Score: 24653
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.81
    Marker Score: 129593
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 3.73
    Marker Score: 3982
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 3.5
    Marker Score: 2986
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.42
    Marker Score: 7498
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.33
    Marker Score: 8139
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 3.24
    Marker Score: 9078
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 3.17
    Marker Score: 2490
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 3.16
    Marker Score: 2393
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.16
    Marker Score: 176662
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.12
    Marker Score: 745
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 3.08
    Marker Score: 6456
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 3.05
    Marker Score: 3008
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 3.01
    Marker Score: 11632.5
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.96
    Marker Score: 29978
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.92
    Marker Score: 154354
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.91
    Marker Score: 1257
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.9
    Marker Score: 7778
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 2.89
    Marker Score: 1296
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.89
    Marker Score: 7283
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.88
    Marker Score: 1167.5
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.87
    Marker Score: 37805
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 2.86
    Marker Score: 14051
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.85
    Marker Score: 2995
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 2.83
    Marker Score: 988
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 2.82
    Marker Score: 748
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.8
    Marker Score: 11727
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 2.8
    Marker Score: 972
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.8
    Marker Score: 11662
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 2.77
    Marker Score: 3345
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.76
    Marker Score: 1844
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 2.74
    Marker Score: 1142
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.74
    Marker Score: 2613
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.73
    Marker Score: 863.5
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 2.73
    Marker Score: 709
  • Cell Name: basal cell (CL0000646)
    Fold Change: 2.72
    Marker Score: 3515
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 2.72
    Marker Score: 1110
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2.71
    Marker Score: 1002
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.7
    Marker Score: 1543
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.69
    Marker Score: 1689
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.69
    Marker Score: 2410
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.69
    Marker Score: 2261
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.68
    Marker Score: 2918
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.68
    Marker Score: 19934
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.67
    Marker Score: 1336
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.65
    Marker Score: 2006
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.65
    Marker Score: 2477
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 2.64
    Marker Score: 921
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 2.64
    Marker Score: 741
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 2.63
    Marker Score: 1798
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.63
    Marker Score: 17125
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.63
    Marker Score: 8304
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 2.63
    Marker Score: 2539
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 2.62
    Marker Score: 600
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 2.61
    Marker Score: 988
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.61
    Marker Score: 1570
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 2.6
    Marker Score: 3048
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 2.6
    Marker Score: 1831
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 2.59
    Marker Score: 568
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.59
    Marker Score: 3668.5
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 2.58
    Marker Score: 1195
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.57
    Marker Score: 1873
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 2.56
    Marker Score: 2351
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.56
    Marker Score: 2404
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 2.55
    Marker Score: 1594
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 2.55
    Marker Score: 903
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.55
    Marker Score: 2008
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 2.54
    Marker Score: 725.5
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.54
    Marker Score: 2918
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 2.53
    Marker Score: 910
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.53
    Marker Score: 1679
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.5
    Marker Score: 2656
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: 2.5
    Marker Score: 711
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 2.5
    Marker Score: 8593
  • Cell Name: lung neuroendocrine cell (CL1000223)
    Fold Change: 2.5
    Marker Score: 705
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.5
    Marker Score: 5219
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 2.5
    Marker Score: 774
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: 2.48
    Marker Score: 1285
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.48
    Marker Score: 1378
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.48
    Marker Score: 738
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 2.47
    Marker Score: 2390
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 2.47
    Marker Score: 757
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 2.47
    Marker Score: 1200
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 2.46
    Marker Score: 573
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 2.46
    Marker Score: 1412
  • Cell Name: epithelial cell of sweat gland (CL1000448)
    Fold Change: 2.46
    Marker Score: 753
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 2.45
    Marker Score: 808
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 2.45
    Marker Score: 1670.5
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 2.45
    Marker Score: 4596
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 2.44
    Marker Score: 4005.5
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.44
    Marker Score: 4254
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 2.44
    Marker Score: 4357
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.44
    Marker Score: 2602.5
  • Cell Name: S cone cell (CL0003050)
    Fold Change: 2.43
    Marker Score: 731
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 2.43
    Marker Score: 2170
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.43
    Marker Score: 27369
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 2.43
    Marker Score: 616
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.43
    Marker Score: 2776.5
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 2.43
    Marker Score: 599
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 2.42
    Marker Score: 736

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** - HNRNPU is a large protein with a molecular weight of approximately 110 kDa. - It is a member of the hnRNP family of proteins, which are characterized by their ability to bind to both DNA and RNA molecules. - HNRNPU is found in a variety of cellular compartments, including the nucleus, cytoplasm, and cell membrane. - It is a key component of the splicing machinery of eukaryotic mRNAs, and it is involved in the regulation of gene expression. **Pathways and functions:** - HNRNPU is involved in the processing of pre-mrna by removing a 5' cap and polyadenylation tract. - It is also involved in the splicing of mRNAs, and it can be found in both the pre-splice and mature mRNAs. - HNRNPU is a major regulator of gene expression in a variety of cell types. - It is involved in the regulation of cell proliferation, differentiation, and apoptosis. **Clinical significance:** - Mutations in the HNRNPU gene have been linked to a number of human diseases, including cancer and neurodegenerative disorders. - HNRNPU is a potential therapeutic target for these diseases, as it is involved in the regulation of gene expression in a variety of cell types.

Genular Protein ID: 914217558

Symbol: HNRPU_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q00839 O75507 Q8N174 Q96HY9 Q9BQ09

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 85 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 5 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1628625

Title: Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

PubMed ID: 1628625

DOI: 10.1002/j.1460-2075.1992.tb05331.x

PubMed ID: 7509195

Title: hnRNP-U/SAF-A is encoded by two differentially polyadenylated mRNAs in human cells.

PubMed ID: 7509195

DOI: 10.1016/0167-4781(94)90044-2

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7993898

Title: Major cell surface-located protein substrates of an ecto-protein kinase are homologs of known nuclear proteins.

PubMed ID: 7993898

DOI: 10.1021/bi00253a007

PubMed ID: 1324173

Title: Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.

PubMed ID: 1324173

DOI: 10.1002/j.1460-2075.1992.tb05422.x

PubMed ID: 8068679

Title: Purification of two isoforms of hnRNP-U and characterization of their nucleic acid binding activity.

PubMed ID: 8068679

DOI: 10.1021/bi00200a024

PubMed ID: 8174554

Title: Nucleic-acid-binding properties of hnRNP-U/SAF-A, a nuclear-matrix protein which binds DNA and RNA in vivo and in vitro.

PubMed ID: 8174554

DOI: 10.1111/j.1432-1033.1994.tb18788.x

PubMed ID: 7753047

Title: Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein.

PubMed ID: 7753047

DOI: 10.1016/0161-5890(95)00005-y

PubMed ID: 9204873

Title: The scaffold/matrix attachment region binding protein hnRNP-U (SAF-A) is directly bound to chromosomal DNA in vivo: a chemical cross-linking study.

PubMed ID: 9204873

DOI: 10.1021/bi970480f

PubMed ID: 9105675

Title: The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.

PubMed ID: 9105675

DOI: 10.1016/s0169-328x(96)00238-0

PubMed ID: 9405365

Title: The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown.

PubMed ID: 9405365

DOI: 10.1093/emboj/16.24.7361

PubMed ID: 9353307

Title: The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U.

PubMed ID: 9353307

DOI: 10.1074/jbc.272.45.28471

PubMed ID: 10490622

Title: hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation.

PubMed ID: 10490622

DOI: 10.1128/mcb.19.10.6833

PubMed ID: 10671544

Title: Apoptotic cleavage of scaffold attachment factor A (SAF-A) by caspase-3 occurs at a noncanonical cleavage site.

PubMed ID: 10671544

DOI: 10.1074/jbc.275.7.5031

PubMed ID: 11003645

Title: SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA.

PubMed ID: 11003645

DOI: 10.1128/mcb.20.20.7480-7489.2000

PubMed ID: 11909954

Title: Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by acetylated nucleosomes.

PubMed ID: 11909954

DOI: 10.1128/mcb.22.8.2598-2606.2002

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 14608463

Title: Scaffold attachment factor A (SAF-A) is concentrated in inactive X chromosome territories through its RGG domain.

PubMed ID: 14608463

DOI: 10.1007/s00412-003-0258-0

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15563465

Title: A stable proteinaceous structure in the territory of inactive X chromosomes.

PubMed ID: 15563465

DOI: 10.1074/jbc.c400531200

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 15711563

Title: Actin and hnRNP U cooperate for productive transcription by RNA polymerase II.

PubMed ID: 15711563

DOI: 10.1038/nsmb904

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16916646

Title: Inhibition of HIV-1 gene expression by a fragment of hnRNP U.

PubMed ID: 16916646

DOI: 10.1016/j.molcel.2006.07.021

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17174306

Title: hnRNP-U enhances the expression of specific genes by stabilizing mRNA.

PubMed ID: 17174306

DOI: 10.1016/j.febslet.2006.11.062

PubMed ID: 18082603

Title: Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation.

PubMed ID: 18082603

DOI: 10.1016/j.molcel.2007.09.023

PubMed ID: 17289661

Title: Molecular composition of IMP1 ribonucleoprotein granules.

PubMed ID: 17289661

DOI: 10.1074/mcp.m600346-mcp200

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19617346

Title: Physical and functional interaction between heterochromatin protein 1alpha and the RNA-binding protein heterogeneous nuclear ribonucleoprotein U.

PubMed ID: 19617346

DOI: 10.1074/jbc.m109.037929

PubMed ID: 19808671

Title: Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein.

PubMed ID: 19808671

DOI: 10.1074/jbc.m109.021659

PubMed ID: 19029303

Title: Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

PubMed ID: 19029303

DOI: 10.1261/rna.1175909

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20858735

Title: Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.

PubMed ID: 20858735

DOI: 10.1158/1541-7786.mcr-10-0042

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21242313

Title: The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles.

PubMed ID: 21242313

DOI: 10.1242/jcs.063347

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22325991

Title: Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation.

PubMed ID: 22325991

DOI: 10.1016/j.molcel.2012.01.009

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23811339

Title: H19 inhibits RNA polymerase II-mediated transcription by disrupting the hnRNP U-actin complex.

PubMed ID: 23811339

DOI: 10.1016/j.bbagen.2013.06.026

PubMed ID: 23640942

Title: Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains.

PubMed ID: 23640942

DOI: 10.1515/hsz-2013-0111

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25911097

Title: Gemin5 binds to the survival motor neuron mRNA to regulate SMN expression.

PubMed ID: 25911097

DOI: 10.1074/jbc.m115.646257

PubMed ID: 25616961

Title: ALS-linked mutations in ubiquilin-2 or hnRNPA1 reduce interaction between ubiquilin-2 and hnRNPA1.

PubMed ID: 25616961

DOI: 10.1093/hmg/ddv020

PubMed ID: 25986610

Title: Phosphorylation of SAF-A/hnRNP-U serine 59 by polo-like kinase 1 is required for mitosis.

PubMed ID: 25986610

DOI: 10.1128/mcb.01312-14

PubMed ID: 26244333

Title: Xist exon 7 contributes to the stable localization of Xist RNA on the inactive X-chromosome.

PubMed ID: 26244333

DOI: 10.1371/journal.pgen.1005430

PubMed ID: 26030138

Title: Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

PubMed ID: 26030138

DOI: 10.1371/journal.pone.0128558

PubMed ID: 28622508

Title: SAF-A regulates interphase chromosome structure through oligomerization with chromatin-associated RNAs.

PubMed ID: 28622508

DOI: 10.1016/j.cell.2017.05.029

PubMed ID: 28190768

Title: Serine ADP-ribosylation depends on HPF1.

PubMed ID: 28190768

DOI: 10.1016/j.molcel.2017.01.003

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 23708187

Title: Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1.

PubMed ID: 23708187

DOI: 10.1038/ng.2646

PubMed ID: 25356899

Title: De novo mutations in moderate or severe intellectual disability.

PubMed ID: 25356899

DOI: 10.1371/journal.pgen.1004772

Sequence Information:

  • Length: 825
  • Mass: 90584
  • Checksum: 5D4EC4188436831F
  • Sequence:
    • MSSSPVNVKK LKVSELKEEL KKRRLSDKGL KAELMERLQA ALDDEEAGGR PAMEPGNGSL 
DLGGDSAGRS GAGLEQEAAA GGDEEEEEEE EEEEGISALD GDQMELGEEN GAAGAADSGP 
MEEEEAASED ENGDDQGFQE GEDELGDEEE GAGDENGHGE QQPQPPATQQ QQPQQQRGAA 
KEAAGKSSGP TSLFAVTVAP PGARQGQQQA GGKKKAEGGG GGGRPGAPAA GDGKTEQKGG 
DKKRGVKRPR EDHGRGYFEY IEENKYSRAK SPQPPVEEED EHFDDTVVCL DTYNCDLHFK 
ISRDRLSASS LTMESFAFLW AGGRASYGVS KGKVCFEMKV TEKIPVRHLY TKDIDIHEVR 
IGWSLTTSGM LLGEEEFSYG YSLKGIKTCN CETEDYGEKF DENDVITCFA NFESDEVELS 
YAKNGQDLGV AFKISKEVLA GRPLFPHVLC HNCAVEFNFG QKEKPYFPIP EEYTFIQNVP 
LEDRVRGPKG PEEKKDCEVV MMIGLPGAGK TTWVTKHAAE NPGKYNILGT NTIMDKMMVA 
GFKKQMADTG KLNTLLQRAP QCLGKFIEIA ARKKRNFILD QTNVSAAAQR RKMCLFAGFQ 
RKAVVVCPKD EDYKQRTQKK AEVEGKDLPE HAVLKMKGNF TLPEVAECFD EITYVELQKE 
EAQKLLEQYK EESKKALPPE KKQNTGSKKS NKNKSGKNQF NRGGGHRGRG GFNMRGGNFR 
GGAPGNRGGY NRRGNMPQRG GGGGGSGGIG YPYPRAPVFP GRGSYSNRGN YNRGGMPNRG 
NYNQNFRGRG NNRGYKNQSQ GYNQWQQGQF WGQKPWSQHY HQGYY

Genular Protein ID: 2637126500

Symbol: Q96BA7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96BA7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 722
  • Mass: 79716
  • Checksum: A35C0DA46EAE6FD2
  • Sequence:
    • MELGEENGAA GAADSGPMEE EEAASEDENG DDQGFQEGED ELGDEEEGAG DENGHGEQQP 
QPPATQQQQP QQQRGAAKEA AGKSSGPTSL FAVTVAPPGA RQGQQQAGGK KKAEGGGGGG 
RPGAPAAGDG KTEQKGGDKK RGVKRPREDH GRGYFEYIEE NKYSRAKSPQ PPVEEEDEHF 
DDTVVCLDTY NCDLHFKISR DRLSASSLTM ESFAFLWAGG RASYGVSKGK VCFEMKVTEK 
IPVRHLYTKD IDIHEVRIGW SLTTSGMLLG EEEFSYGYSL KGIKTCNCET EDYGEKFDEN 
DVITCFANFE SDEVELSYAK NGQDLGVAFK ISKEVLAGRP LFPHVLCHNC AVEFNFGQKE 
KPYFPIPEEY TFIQNVPLED RVRGPKGPEE KKDCEVVMMI GLPGAGKTTW VTKHAAENPG 
KYNILGTNTI MDKMMVAGFK KQMADTGKLN TLLQRAPQCL GKFIEIAARK KRNFILDQTN 
VSAAAQRRKM CLFAGFQRKA VVVCPKDEDY KQRTQKKAEV EGKDLPEHAV LKMKGNFTLP 
EVAECFDEIT YVELQKEEAQ KLLEQYKEES KKALPPEKKQ NTGSKKSNKN KSGKNQFNRG 
GGHRGRGGFN MRGGNFRGGA PGNRGGYNRR GNMPQRGGGG GGSGGIGYPY PRAPVFPGRG 
SYSNRGNYNR GGMPNRGNYN QNFRGRGNNR GYKNQSQGYN QWQQGQFWGQ KPWSQHYHQG 
YY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.