Details for: GAPDH

Gene ID: 2597

Symbol: GAPDH

Ensembl ID: ENSG00000111640

Description: glyceraldehyde-3-phosphate dehydrogenase

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 6.37
    Marker Score: 113083
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 5.68
    Marker Score: 7998
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 5.65
    Marker Score: 3192
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 5.46
    Marker Score: 73340
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 5.32
    Marker Score: 4048
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 5.24
    Marker Score: 4195
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 5.19
    Marker Score: 7999
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 5.16
    Marker Score: 51074
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 5.11
    Marker Score: 1884
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 4.76
    Marker Score: 3725
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 4.72
    Marker Score: 8607
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 4.67
    Marker Score: 14744
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 4.63
    Marker Score: 5593
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 4.6
    Marker Score: 13412.5
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.51
    Marker Score: 252448.5
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 4.46
    Marker Score: 11947
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 4.43
    Marker Score: 11273
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 4.42
    Marker Score: 18442
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 4.42
    Marker Score: 58304
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 4.39
    Marker Score: 4138.5
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.36
    Marker Score: 1042
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 4.33
    Marker Score: 15386.5
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 4.31
    Marker Score: 3130
  • Cell Name: blood cell (CL0000081)
    Fold Change: 4.29
    Marker Score: 49913
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 4.28
    Marker Score: 1918
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 4.27
    Marker Score: 4742
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 4.27
    Marker Score: 3010
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 4.26
    Marker Score: 11762
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 4.22
    Marker Score: 2251.5
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 4.2
    Marker Score: 222008
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 4.19
    Marker Score: 31164
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.18
    Marker Score: 10218.5
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 4.17
    Marker Score: 3144
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 4.15
    Marker Score: 141291
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 4.15
    Marker Score: 2523
  • Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
    Fold Change: 4.13
    Marker Score: 1878
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 4.12
    Marker Score: 1855.5
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 4.05
    Marker Score: 3912.5
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 4.05
    Marker Score: 4884
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 4.04
    Marker Score: 2367
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 3.98
    Marker Score: 11161
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 3.97
    Marker Score: 17014.5
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 3.96
    Marker Score: 1048
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 3.94
    Marker Score: 5808
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 3.93
    Marker Score: 2022
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 3.93
    Marker Score: 9915
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 3.91
    Marker Score: 5653
  • Cell Name: muscle precursor cell (CL0000680)
    Fold Change: 3.9
    Marker Score: 1010
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 3.89
    Marker Score: 3317
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 3.89
    Marker Score: 3358
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 3.88
    Marker Score: 6654.5
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 3.88
    Marker Score: 2758
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.87
    Marker Score: 12674
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 3.87
    Marker Score: 1273
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 3.86
    Marker Score: 3458
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 3.86
    Marker Score: 1666
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 3.83
    Marker Score: 1008.5
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 3.83
    Marker Score: 4085
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 3.82
    Marker Score: 875
  • Cell Name: naive T cell (CL0000898)
    Fold Change: 3.8
    Marker Score: 2448
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 3.78
    Marker Score: 1976
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 3.78
    Marker Score: 33193
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 3.78
    Marker Score: 2360
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 3.77
    Marker Score: 8580.5
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 3.75
    Marker Score: 1939
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 3.74
    Marker Score: 2933.5
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 3.72
    Marker Score: 2264
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 3.7
    Marker Score: 1186.5
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.69
    Marker Score: 24029.5
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 3.69
    Marker Score: 1505
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 3.68
    Marker Score: 3100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 3.68
    Marker Score: 21811.5
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 3.67
    Marker Score: 2413
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 3.66
    Marker Score: 1276.5
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 3.66
    Marker Score: 6871
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 3.65
    Marker Score: 3928
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 3.65
    Marker Score: 3031
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 3.65
    Marker Score: 3243
  • Cell Name: theca cell (CL0000503)
    Fold Change: 3.64
    Marker Score: 2610
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 3.64
    Marker Score: 10386
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 3.63
    Marker Score: 4148
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 3.62
    Marker Score: 3941
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 3.61
    Marker Score: 11348
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 3.61
    Marker Score: 3183
  • Cell Name: meningeal macrophage (CL0000879)
    Fold Change: 3.6
    Marker Score: 1015
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 3.59
    Marker Score: 1025
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 3.58
    Marker Score: 5865
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 3.57
    Marker Score: 4215
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: 3.55
    Marker Score: 1839
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 3.55
    Marker Score: 17432
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 3.54
    Marker Score: 1291
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 3.54
    Marker Score: 27621.5
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: 3.54
    Marker Score: 2216.5
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 3.53
    Marker Score: 4598
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 3.52
    Marker Score: 1267
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 3.52
    Marker Score: 933.5
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 3.52
    Marker Score: 3572
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 3.52
    Marker Score: 22452
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 3.52
    Marker Score: 3397
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 3.51
    Marker Score: 2982

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** * The protein is a glycoprotein with a molecular weight of approximately 130 kDa. * It is expressed in various cell types, including epithelial cells, hepatocytes, and immune cells. * It is a homodimeric protein, meaning it consists of two identical subunits. * It is involved in the regulation of glucose metabolism, including the production of ATP (adenosine triphosphate), which is essential for various cellular processes. **Pathways and functions:** * **Aspartic-type endopeptidase inhibitor activity:** GAPDH is a key enzyme in the regulation of protein degradation. It inhibits the activity of aspartic proteases, which are enzymes that break down proteins into smaller molecules. By inhibiting aspartic proteases, GAPDH prevents the degradation of proteins involved in cell signaling, proliferation, and apoptosis (programmed cell death). * **Disordered domain specific binding:** GAPDH has a disordered domain that is not involved in the catalytic activity but plays a role in protein-protein interactions. This domain interacts with other proteins involved in cell signaling and regulation. * **Gluconeogenesis:** GAPDH is involved in the regulation of gluconeogenesis, the process of converting non-carbohydrate substrates into glucose. It is an enzyme in the citric acid cycle, where it converts pyruvate into oxaloacetate. * **Glucose metabolism:** GAPDH is involved in the metabolism of glucose, including the production of glucose-6-phosphate (G6P), which is a precursor for many important biomolecules. * **Glyceraldehyde-3-phosphate dehydrogenase (nad+) (phosphorylating):** GAPDH is an enzyme in the glycolytic pathway, where it catalyzes the phosphorylation of G3P to G3P-phosphate. This reaction is a key step in the production of ATP. * **Glycolysis:** GAPDH is involved in the glycolytic pathway, where it catalyzes the phosphorylation of G3P to G3P-phosphate. * **Identical protein binding:** GAPDH has a similar protein (GAPDH-like protein) in the plasma membrane of red blood cells. This interaction is important for the transport of oxygen in red blood cells. * **Metabolic process:** GAPDH is involved in various metabolic processes, including protein degradation, gluconeogenesis, glucose metabolism, and the regulation of inflammation. **Clinical significance:** * Mutations in the GAPDH gene have been linked to several human diseases, including diabetes, obesity, and cancer. * Overexpression of GAPDH has been associated with certain types of cancer, such as breast cancer and lung cancer. * Inhibition of GAPDH has been shown to suppress cancer growth and metastasis.

Genular Protein ID: 754703678

Symbol: G3P_HUMAN

Name: N/A

UniProtKB Accession Codes:

P04406 E7EUT4 P00354 Q53X65

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CPTAC 4 CPTC 1 CTD 1 ChEBI 17 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DOSAC-COBS-2DPAGE 1 DisGeNET 1 DrugBank 7 DrugCentral 1 EC 1 EMBL 23 EMDB 1 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 39 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonDB 1 MoonProt 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PDB 15 PDBsum 14 PIR 1 PRIDE 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 2 RefSeq 4 Rhea 7 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 6096136

Title: The glyceraldehyde 3 phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse.

PubMed ID: 6096136

DOI: 10.1002/j.1460-2075.1984.tb02185.x

PubMed ID: 6096821

Title: The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species.

PubMed ID: 6096821

DOI: 10.1093/nar/12.23.9179

PubMed ID: 2987855

Title: Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene.

PubMed ID: 2987855

DOI: 10.1093/nar/13.7.2485

PubMed ID: 3664468

Title: Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers.

PubMed ID: 3664468

PubMed ID: 3027061

Title: Identification of the 37-kDa protein displaying a variable interaction with the erythroid cell membrane as glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 3027061

DOI: 10.1016/s0021-9258(19)75833-5

PubMed ID: 3170585

Title: Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene.

PubMed ID: 3170585

DOI: 10.1016/s0021-9258(19)37593-3

PubMed ID: 1924305

Title: A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 1924305

DOI: 10.1073/pnas.88.19.8460

PubMed ID: 10944468

Title: cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.

PubMed ID: 10944468

DOI: 10.1006/bbrc.2000.3282

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7030790

Title: The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase.

PubMed ID: 7030790

DOI: 10.1016/0014-5793(81)80587-x

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 7498159

Title: The major protein expression profile and two-dimensional protein database of human heart.

PubMed ID: 7498159

DOI: 10.1002/elps.11501601192

PubMed ID: 1193541

Title: The covalent structure of glyceraldehyde-phosphate dehydrogenase from human muscles. Isolation and amino acid sequences of peptides from tryptic digest.

PubMed ID: 1193541

PubMed ID: 11724794

Title: Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway.

PubMed ID: 11724794

DOI: 10.1074/jbc.m109744200

PubMed ID: 12829261

Title: Subcellular localization of human glyceraldehyde-3-phosphate dehydrogenase is independent of its glycolytic function.

PubMed ID: 12829261

DOI: 10.1016/s0304-4165(03)00117-x

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15479637

Title: Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation.

PubMed ID: 15479637

DOI: 10.1016/j.cell.2004.09.030

PubMed ID: 15628863

Title: Oxidative stress-responsive intracellular regulation specific for the angiostatic form of human tryptophanyl-tRNA synthetase.

PubMed ID: 15628863

DOI: 10.1021/bi048313k

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16501887

Title: The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.

PubMed ID: 16501887

DOI: 10.1007/s00018-005-5533-1

PubMed ID: 16815975

Title: HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets.

PubMed ID: 16815975

DOI: 10.1073/pnas.0600397103

PubMed ID: 18183946

Title: Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 18183946

DOI: 10.1021/pr700657y

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19001379

Title: FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor.

PubMed ID: 19001379

DOI: 10.1074/jbc.m709779200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20644585

Title: Haponin (eIF1AD) interacts with glyceraldehyde 3-phosphate dehydrogenase in the CHO-K1 cell line.

PubMed ID: 20644585

DOI: 10.1134/s1068162010030027

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21908771

Title: The first identification of lysine malonylation substrates and its regulatory enzyme.

PubMed ID: 21908771

DOI: 10.1074/mcp.m111.012658

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 22771119

Title: Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation.

PubMed ID: 22771119

DOI: 10.1016/j.molcel.2012.06.006

PubMed ID: 23071094

Title: Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.

PubMed ID: 23071094

DOI: 10.1128/mcb.01168-12

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23332158

Title: NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-kappaB activation.

PubMed ID: 23332158

DOI: 10.1016/j.chom.2012.11.010

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25417112

Title: Target-selective protein S-nitrosylation by sequence motif recognition.

PubMed ID: 25417112

DOI: 10.1016/j.cell.2014.09.032

PubMed ID: 25086035

Title: Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 25086035

DOI: 10.1074/jbc.m114.570275

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27387501

Title: Citrobacter rodentium NleB protein inhibits tumor necrosis factor (TNF) receptor-associated factor 3 (TRAF3) ubiquitination to reduce host type I interferon production.

PubMed ID: 27387501

DOI: 10.1074/jbc.m116.738278

PubMed ID: 28522607

Title: NleB/SseK effectors from Citrobacter rodentium, Escherichia coli, and Salmonella enterica display distinct differences in host substrate specificity.

PubMed ID: 28522607

DOI: 10.1074/jbc.m117.790675

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 957435

Title: Twinning in crystals of human skeletal muscle D-glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 957435

DOI: 10.1016/0022-2836(76)90013-9

PubMed ID: 16239728

Title: Structural analysis of human liver glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 16239728

DOI: 10.1107/s0907444905026740

PubMed ID: 16510976

Title: High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase.

PubMed ID: 16510976

DOI: 10.1107/s0907444905042289

Sequence Information:

  • Length: 335
  • Mass: 36053
  • Checksum: C9C135E8AE3E8744
  • Sequence:
    • MGKVKVGVNG FGRIGRLVTR AAFNSGKVDI VAINDPFIDL NYMVYMFQYD STHGKFHGTV 
KAENGKLVIN GNPITIFQER DPSKIKWGDA GAEYVVESTG VFTTMEKAGA HLQGGAKRVI 
ISAPSADAPM FVMGVNHEKY DNSLKIISNA SCTTNCLAPL AKVIHDNFGI VEGLMTTVHA 
ITATQKTVDG PSGKLWRDGR GALQNIIPAS TGAAKAVGKV IPELNGKLTG MAFRVPTANV 
SVVDLTCRLE KPAKYDDIKK VVKQASEGPL KGILGYTEHQ VVSSDFNSDT HSSTFDAGAG 
IALNDHFVKL ISWYDNEFGY SNRVVDLMAH MASKE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.