Details for: NDUFA4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 876.5296
Cell Significance Index: -136.3400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 523.0375
Cell Significance Index: -132.6700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 410.5619
Cell Significance Index: -169.1300 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 350.8410
Cell Significance Index: -165.6400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 348.8185
Cell Significance Index: -141.7100 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 311.2453
Cell Significance Index: -160.1000 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 249.9619
Cell Significance Index: -167.7300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 150.4279
Cell Significance Index: -143.6200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 129.7492
Cell Significance Index: -159.9800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 43.5879
Cell Significance Index: -172.0000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 40.6550
Cell Significance Index: -124.8700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 35.6868
Cell Significance Index: -95.6000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 10.5265
Cell Significance Index: 552.6800 - Cell Name: peg cell (CL4033014)
Fold Change: 6.8561
Cell Significance Index: 158.4000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 5.9917
Cell Significance Index: 279.3600 - Cell Name: kidney cell (CL1000497)
Fold Change: 5.8766
Cell Significance Index: 46.9200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 5.2494
Cell Significance Index: 246.7200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 4.9964
Cell Significance Index: 131.3800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 4.8818
Cell Significance Index: 670.4100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 4.5040
Cell Significance Index: 811.9300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 4.4927
Cell Significance Index: 334.8400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 4.3023
Cell Significance Index: 2349.6100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 4.2714
Cell Significance Index: 525.2100 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 4.1892
Cell Significance Index: 32.2900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 4.0923
Cell Significance Index: 142.2100 - Cell Name: lactocyte (CL0002325)
Fold Change: 3.8560
Cell Significance Index: 498.1700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 3.7284
Cell Significance Index: 263.6900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 3.7150
Cell Significance Index: 34.2100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 3.6917
Cell Significance Index: 435.3600 - Cell Name: odontoblast (CL0000060)
Fold Change: 3.6800
Cell Significance Index: 471.7500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 3.5630
Cell Significance Index: 74.5800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 3.5381
Cell Significance Index: 1564.2700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.7754
Cell Significance Index: 31.5300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.6246
Cell Significance Index: 71.4400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.3050
Cell Significance Index: 67.7000 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 1.9267
Cell Significance Index: 11.8600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.9252
Cell Significance Index: 124.2100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.6787
Cell Significance Index: 18.2500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 1.5823
Cell Significance Index: 1160.1200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 1.4944
Cell Significance Index: 118.3600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.2618
Cell Significance Index: 79.5300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.0989
Cell Significance Index: 220.4400 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.0975
Cell Significance Index: 14.0600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.0824
Cell Significance Index: 184.8200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 1.0777
Cell Significance Index: 815.7200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7644
Cell Significance Index: 39.7100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.7399
Cell Significance Index: 13.0800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5501
Cell Significance Index: 109.1700 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.5410
Cell Significance Index: 10.0000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5022
Cell Significance Index: 180.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2902
Cell Significance Index: 55.2200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.2214
Cell Significance Index: 3.7100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1773
Cell Significance Index: 10.9000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1207
Cell Significance Index: 5.4700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0959
Cell Significance Index: 2.5600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0117
Cell Significance Index: 0.6100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0305
Cell Significance Index: -57.3700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0362
Cell Significance Index: -26.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0737
Cell Significance Index: -7.5300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0941
Cell Significance Index: -173.6300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1097
Cell Significance Index: -168.8800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1362
Cell Significance Index: -185.1400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.1492
Cell Significance Index: -14.7600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.1524
Cell Significance Index: -96.8200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1603
Cell Significance Index: -100.1000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2037
Cell Significance Index: -114.9000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.2270
Cell Significance Index: -103.0300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2305
Cell Significance Index: -3.9500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3868
Cell Significance Index: -44.3100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3877
Cell Significance Index: -11.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.4760
Cell Significance Index: -136.9600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.5387
Cell Significance Index: -113.4600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.5615
Cell Significance Index: -91.3200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.7104
Cell Significance Index: -82.7900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.7308
Cell Significance Index: -18.6700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.7614
Cell Significance Index: -21.8300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7841
Cell Significance Index: -19.6000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.8372
Cell Significance Index: -95.5700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.8524
Cell Significance Index: -123.9100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.1120
Cell Significance Index: -85.3300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.1590
Cell Significance Index: -25.1100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -1.2281
Cell Significance Index: -14.6400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.3000
Cell Significance Index: -36.3300 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -1.3510
Cell Significance Index: -28.1800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -1.4485
Cell Significance Index: -97.4000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -1.5131
Cell Significance Index: -84.9100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.5757
Cell Significance Index: -164.0700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -1.5888
Cell Significance Index: -95.3800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.7416
Cell Significance Index: -55.7800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -1.9096
Cell Significance Index: -67.1000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -2.0226
Cell Significance Index: -54.1000 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -2.1060
Cell Significance Index: -17.6900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -2.4940
Cell Significance Index: -37.3700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -2.7185
Cell Significance Index: -166.6700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -2.7661
Cell Significance Index: -37.7400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -2.8587
Cell Significance Index: -84.2000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -3.0294
Cell Significance Index: -44.7300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -3.1466
Cell Significance Index: -139.1800 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: -3.2853
Cell Significance Index: -28.9400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -3.4595
Cell Significance Index: -84.4100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2299174111
Symbol: NDUA4_HUMAN
Name: Cytochrome c oxidase subunit NDUFA4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9352085
Title: Cloning of the human cDNA sequence encoding the NADH:ubiquinone oxidoreductase MLRQ subunit.
PubMed ID: 9352085
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12611891
Title: The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.
PubMed ID: 12611891
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22902835
Title: NDUFA4 is a subunit of complex IV of the mammalian electron transport chain.
PubMed ID: 22902835
PubMed ID: 23746447
Title: NDUFA4 mutations underlie dysfunction of a cytochrome c oxidase subunit linked to human neurological disease.
PubMed ID: 23746447
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 31536960
Title: Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
PubMed ID: 31536960
PubMed ID: 30030519
Title: Structure of the intact 14-subunit human cytochrome c oxidase.
PubMed ID: 30030519
Sequence Information:
- Length: 81
- Mass: 9370
- Checksum: 2FA1D1115EDE24C7
- Sequence:
MLRQIIGQAK KHPSLIPLFV FIGTGATGAT LYLLRLALFN PDVCWDRNNP EPWNKLGPND QYKFYSVNVD YSKLKKERPD F
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.