Details for: PRDX1

Gene ID: 5052

Symbol: PRDX1

Ensembl ID: ENSG00000117450

Description: peroxiredoxin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 854.2853
    Cell Significance Index: -132.8800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 397.9209
    Cell Significance Index: -100.9300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 358.4922
    Cell Significance Index: -147.6800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 308.8684
    Cell Significance Index: -125.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 305.0849
    Cell Significance Index: -144.0400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 271.7953
    Cell Significance Index: -139.8100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 215.9839
    Cell Significance Index: -144.9300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 131.7004
    Cell Significance Index: -125.7400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 113.5564
    Cell Significance Index: -140.0100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 44.7504
    Cell Significance Index: -119.8800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 37.4932
    Cell Significance Index: -147.9500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 33.5867
    Cell Significance Index: -103.1600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 22.9509
    Cell Significance Index: -50.2300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 6.8967
    Cell Significance Index: 63.5100
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 6.1923
    Cell Significance Index: 53.2100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 6.1291
    Cell Significance Index: 288.0600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 5.1559
    Cell Significance Index: 332.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.8098
    Cell Significance Index: 130.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 4.5089
    Cell Significance Index: 554.4100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 4.4985
    Cell Significance Index: 810.9400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.4901
    Cell Significance Index: 131.8700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.4681
    Cell Significance Index: 2440.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 4.3497
    Cell Significance Index: 557.6000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 4.2584
    Cell Significance Index: 122.0700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 3.7429
    Cell Significance Index: 98.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.7267
    Cell Significance Index: 439.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.5399
    Cell Significance Index: 486.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 3.3928
    Cell Significance Index: 158.1900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 3.3590
    Cell Significance Index: 38.1600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.1678
    Cell Significance Index: 236.0900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 2.8228
    Cell Significance Index: 1248.0300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.7307
    Cell Significance Index: 193.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.0782
    Cell Significance Index: 43.5000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.0727
    Cell Significance Index: 267.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.9378
    Cell Significance Index: 315.1700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.9298
    Cell Significance Index: 67.0600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6583
    Cell Significance Index: 44.2800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5807
    Cell Significance Index: 313.7000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.5599
    Cell Significance Index: 9.6000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.3474
    Cell Significance Index: 31.1300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.0933
    Cell Significance Index: 19.3200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0243
    Cell Significance Index: 53.2100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.7285
    Cell Significance Index: 7.9200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6143
    Cell Significance Index: 60.7700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4763
    Cell Significance Index: 30.0200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.3244
    Cell Significance Index: 245.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3188
    Cell Significance Index: 60.6700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.2595
    Cell Significance Index: 190.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2125
    Cell Significance Index: 42.6300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1911
    Cell Significance Index: 5.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1872
    Cell Significance Index: 11.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1387
    Cell Significance Index: 23.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0226
    Cell Significance Index: 8.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0250
    Cell Significance Index: -47.0200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0402
    Cell Significance Index: -4.1100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0583
    Cell Significance Index: -0.9800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0807
    Cell Significance Index: -59.7500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0845
    Cell Significance Index: -155.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1009
    Cell Significance Index: -3.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.1030
    Cell Significance Index: -158.5000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1150
    Cell Significance Index: -6.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1194
    Cell Significance Index: -74.5600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1261
    Cell Significance Index: -171.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1501
    Cell Significance Index: -95.3500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1705
    Cell Significance Index: -96.1600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2161
    Cell Significance Index: -6.0400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2558
    Cell Significance Index: -116.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2796
    Cell Significance Index: -80.4400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3967
    Cell Significance Index: -31.4200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.4446
    Cell Significance Index: -3.5500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4502
    Cell Significance Index: -8.3200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4618
    Cell Significance Index: -97.2600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5683
    Cell Significance Index: -65.1100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5776
    Cell Significance Index: -7.8800
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.7185
    Cell Significance Index: -5.4200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.7344
    Cell Significance Index: -9.4100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7496
    Cell Significance Index: -85.5700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7672
    Cell Significance Index: -19.6000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7787
    Cell Significance Index: -20.8300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.7823
    Cell Significance Index: -91.1700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.7891
    Cell Significance Index: -114.7000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.9230
    Cell Significance Index: -63.8300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.9384
    Cell Significance Index: -57.6800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.0115
    Cell Significance Index: -25.2900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.1979
    Cell Significance Index: -14.2800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.3314
    Cell Significance Index: -28.8500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.4006
    Cell Significance Index: -145.8400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4432
    Cell Significance Index: -46.2200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.4731
    Cell Significance Index: -8.9000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.8237
    Cell Significance Index: -139.9500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.9586
    Cell Significance Index: -131.7000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -2.0193
    Cell Significance Index: -113.3100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -2.0774
    Cell Significance Index: -108.2100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -2.0822
    Cell Significance Index: -31.2000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -2.1510
    Cell Significance Index: -13.3700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -2.1923
    Cell Significance Index: -37.5700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -2.2416
    Cell Significance Index: -60.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -2.2589
    Cell Significance Index: -102.3900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.3298
    Cell Significance Index: -142.8400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.6122
    Cell Significance Index: -76.9400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PRDX1 is a small, cytosolic enzyme that belongs to the peroxiredoxin family of antioxidant enzymes. It is characterized by its ability to catalyze the reduction of hydrogen peroxide and other ROS, using thioredoxin as a reducing agent. PRDX1 has a unique catalytic mechanism that involves the oxidation of thioredoxin, followed by the reduction of the substrate. This enzyme is highly sensitive to oxidative stress and is rapidly inactivated by high levels of ROS. PRDX1 is also a substrate for the Keap1-NFE2L2 pathway, which regulates its expression and activity. **Pathways and Functions** PRDX1 plays a crucial role in maintaining redox homeostasis within cells by catalyzing the reduction of hydrogen peroxide and other ROS. This enzyme is involved in various cellular processes, including: 1. **Cellular responses to stress**: PRDX1 is activated in response to oxidative stress and helps to protect cells from damage caused by ROS. 2. **Detoxification of reactive oxygen species**: PRDX1 catalyzes the reduction of hydrogen peroxide and other ROS, thereby removing them from the cell. 3. **Regulation of non-canonical NF-κB signaling**: PRDX1 is a substrate for the Keap1-NFE2L2 pathway, which regulates its expression and activity. 4. **Regulation of stress-activated MAPK cascade**: PRDX1 is involved in the regulation of the stress-activated MAPK cascade, which is involved in cell proliferation, differentiation, and survival. 5. **Regulation of apoptosis**: PRDX1 is involved in the regulation of apoptosis, particularly in the context of oxidative stress. **Clinical Significance** PRDX1 has been implicated in various diseases, including: 1. **Neurodegenerative diseases**: PRDX1 has been shown to play a role in the regulation of stress responses and the detoxification of ROS in the brain, making it a potential target for the treatment of neurodegenerative diseases such as Alzheimer's disease. 2. **Cancer**: PRDX1 has been shown to be overexpressed in various types of cancer, including breast, prostate, and lung cancer, and has been implicated in the regulation of cell proliferation and survival. 3. **Atherosclerosis**: PRDX1 has been shown to play a role in the regulation of oxidative stress and inflammation in the vascular wall, making it a potential target for the treatment of atherosclerosis. 4. **Inflammatory diseases**: PRDX1 has been shown to be involved in the regulation of inflammation and immune responses, making it a potential target for the treatment of inflammatory diseases such as rheumatoid arthritis and asthma. In conclusion, PRDX1 is a critical enzyme that plays a key role in maintaining redox homeostasis within cells and regulating various cellular processes, including stress responses, detoxification of ROS, and regulation of apoptosis. Its dysregulation has been implicated in various diseases, making it a potential target for the treatment of these conditions.

Genular Protein ID: 3592725605

Symbol: PRDX1_HUMAN

Name: Peroxiredoxin-1

UniProtKB Accession Codes:

Q06830 B5BU26 D3DPZ8 P35703 Q2V576 Q5T154 Q5T155

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 7 EC 1 EMBL 17 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PeroxiBase 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 4 Rhea 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8496166

Title: A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins.

PubMed ID: 8496166

DOI: 10.1016/s0021-9258(18)82090-7

PubMed ID: 8026862

Title: Cloning and sequence analysis of candidate human natural killer-enhancing factor genes.

PubMed ID: 8026862

DOI: 10.1007/bf00188176

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9497357

Title: Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.

PubMed ID: 9497357

DOI: 10.1074/jbc.273.11.6297

PubMed ID: 12059788

Title: A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress.

PubMed ID: 12059788

DOI: 10.1042/bj20020525

PubMed ID: 11986303

Title: Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation.

PubMed ID: 11986303

DOI: 10.1074/jbc.m110432200

PubMed ID: 12161445

Title: Inactivation of human peroxiredoxin I during catalysis as the result of the oxidation of the catalytic site cysteine to cysteine-sulfinic acid.

PubMed ID: 12161445

DOI: 10.1074/jbc.m206626200

PubMed ID: 12853451

Title: Regeneration of peroxiredoxins during recovery after oxidative stress: only some overoxidized peroxiredoxins can be reduced during recovery after oxidative stress.

PubMed ID: 12853451

DOI: 10.1074/jbc.m305161200

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 12714748

Title: Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation.

PubMed ID: 12714748

DOI: 10.1126/science.1080273

PubMed ID: 15105503

Title: Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD.

PubMed ID: 15105503

DOI: 10.1126/science.1095569

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21969592

Title: Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition.

PubMed ID: 21969592

DOI: 10.1073/pnas.1103318108

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 18172504

Title: Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace.

PubMed ID: 18172504

DOI: 10.1038/nature06415

PubMed ID: 19812042

Title: Protein engineering of the quaternary sulfiredoxin.peroxiredoxin enzyme.substrate complex reveals the molecular basis for cysteine sulfinic acid phosphorylation.

PubMed ID: 19812042

DOI: 10.1074/jbc.m109.036400

Title: Crystal structure of dimeric human peroxiredoxin-1 C83S mutant.

DOI: 10.1002/bkcs.10284

Sequence Information:

  • Length: 199
  • Mass: 22110
  • Checksum: 8F68E56D75BF5304
  • Sequence:
    • MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS 
DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK 
ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG 
SDTIKPDVQK SKEYFSKQK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.