Details for: FOS
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 5.41
Marker Score: 7,041 - Cell Name: acinar cell (CL0000622)
Fold Change: 4.68
Marker Score: 3,302 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 4.59
Marker Score: 7,065 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 4.57
Marker Score: 3,658 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.33
Marker Score: 241,946 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 4.21
Marker Score: 11,641 - Cell Name: theca cell (CL0000503)
Fold Change: 4.21
Marker Score: 3,015 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 4.09
Marker Score: 17,518 - Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 4.02
Marker Score: 2,264 - Cell Name: IgA plasma cell (CL0000987)
Fold Change: 3.95
Marker Score: 3,362 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.9
Marker Score: 132,747 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 3.9
Marker Score: 3,371 - Cell Name: blood cell (CL0000081)
Fold Change: 3.87
Marker Score: 44,978 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 3.82
Marker Score: 10,711 - Cell Name: myelocyte (CL0002193)
Fold Change: 3.81
Marker Score: 1,645 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 3.76
Marker Score: 2,851 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 3.73
Marker Score: 8,500 - Cell Name: supporting cell (CL0000630)
Fold Change: 3.73
Marker Score: 7,005 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 3.71
Marker Score: 19,490 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 3.65
Marker Score: 23,256 - Cell Name: lung macrophage (CL1001603)
Fold Change: 3.63
Marker Score: 4,148 - Cell Name: endocrine cell (CL0000163)
Fold Change: 3.62
Marker Score: 1,875 - Cell Name: memory T cell (CL0000813)
Fold Change: 3.62
Marker Score: 1,557 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 3.52
Marker Score: 2,760 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 3.47
Marker Score: 2,722 - Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 3.42
Marker Score: 1,756 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 3.39
Marker Score: 4,092 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 3.36
Marker Score: 2,439 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 3.36
Marker Score: 4,639 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.35
Marker Score: 4,047 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 3.33
Marker Score: 8,462 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 3.32
Marker Score: 8,007 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 3.32
Marker Score: 6,625 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.3
Marker Score: 21,451 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 3.3
Marker Score: 3,109 - Cell Name: naive T cell (CL0000898)
Fold Change: 3.29
Marker Score: 2,122 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 3.29
Marker Score: 2,829 - Cell Name: mature T cell (CL0002419)
Fold Change: 3.28
Marker Score: 32,523 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 3.26
Marker Score: 3,124 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 3.24
Marker Score: 3,463 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 3.21
Marker Score: 8,402 - Cell Name: basophil (CL0000767)
Fold Change: 3.16
Marker Score: 1,502 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 3.16
Marker Score: 20,602 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 3.15
Marker Score: 2,800 - Cell Name: fibroblast (CL0000057)
Fold Change: 3.15
Marker Score: 3,039 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 3.14
Marker Score: 4,624 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 3.14
Marker Score: 6,572 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 3.13
Marker Score: 6,102 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 3.13
Marker Score: 2,290 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 3.11
Marker Score: 3,115 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 3.07
Marker Score: 6,973 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 3.06
Marker Score: 768 - Cell Name: neutrophil (CL0000775)
Fold Change: 3.04
Marker Score: 1,852 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 3.01
Marker Score: 1,850 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.95
Marker Score: 4,846 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.94
Marker Score: 101,798 - Cell Name: naive B cell (CL0000788)
Fold Change: 2.92
Marker Score: 2,608 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.9
Marker Score: 9,111 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.9
Marker Score: 32,636 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.9
Marker Score: 38,202 - Cell Name: chondrocyte (CL0000138)
Fold Change: 2.88
Marker Score: 1,298 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 2.88
Marker Score: 8,413 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.87
Marker Score: 4,866 - Cell Name: basal cell (CL0000646)
Fold Change: 2.87
Marker Score: 3,709 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.87
Marker Score: 12,384 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.87
Marker Score: 1,084 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 2.86
Marker Score: 1,428 - Cell Name: epithelial cell (CL0000066)
Fold Change: 2.86
Marker Score: 4,544 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 2.84
Marker Score: 1,663 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.83
Marker Score: 676 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 2.83
Marker Score: 2,317 - Cell Name: immature B cell (CL0000816)
Fold Change: 2.81
Marker Score: 1,861 - Cell Name: paneth cell (CL0000510)
Fold Change: 2.8
Marker Score: 1,949 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 2.78
Marker Score: 1,832 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 2.77
Marker Score: 956 - Cell Name: club cell (CL0000158)
Fold Change: 2.76
Marker Score: 3,222 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 2.76
Marker Score: 1,185 - Cell Name: type L enteroendocrine cell (CL0002279)
Fold Change: 2.74
Marker Score: 747 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 2.73
Marker Score: 16,201 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 2.73
Marker Score: 3,952 - Cell Name: Mueller cell (CL0000636)
Fold Change: 2.73
Marker Score: 3,784 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 2.72
Marker Score: 1,408 - Cell Name: stromal cell (CL0000499)
Fold Change: 2.71
Marker Score: 3,173 - Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 2.71
Marker Score: 3,007 - Cell Name: pericyte (CL0000669)
Fold Change: 2.7
Marker Score: 1,580 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 2.7
Marker Score: 2,941 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 2.69
Marker Score: 626 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.69
Marker Score: 68,822 - Cell Name: enterocyte (CL0000584)
Fold Change: 2.68
Marker Score: 12,865 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 2.67
Marker Score: 1,114 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 2.67
Marker Score: 1,213 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 2.67
Marker Score: 1,151 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 2.66
Marker Score: 826 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 2.66
Marker Score: 1,244 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 2.66
Marker Score: 3,205 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.66
Marker Score: 26,916 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.63
Marker Score: 3,251 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.62
Marker Score: 3,812 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.62
Marker Score: 5,462 - Cell Name: Unknown (CL0000548)
Fold Change: 2.61
Marker Score: 1,905
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 841333319
Symbol: FOS_HUMAN
Name: Cellular oncogene fos
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 6574479
Title: Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.
PubMed ID: 6574479
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1658710
Title: Retrovirus-mediated gene transfer of a human c-fos cDNA into mouse bone marrow stromal cells.
PubMed ID: 1658710
PubMed ID: 2516827
Title: Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.
PubMed ID: 2516827
PubMed ID: 2511004
Title: The basic region of Fos mediates specific DNA binding.
PubMed ID: 2511004
PubMed ID: 7588633
Title: The Mos/MAP kinase pathway stabilizes c-Fos by phosphorylation and augments its transforming activity in NIH 3T3 cells.
PubMed ID: 7588633
PubMed ID: 9732876
Title: Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription.
PubMed ID: 9732876
DOI: 10.1038/29814
PubMed ID: 12134156
Title: Molecular interpretation of ERK signal duration by immediate early gene products.
PubMed ID: 12134156
DOI: 10.1038/ncb822
PubMed ID: 16055710
Title: Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation.
PubMed ID: 16055710
PubMed ID: 17709345
Title: Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation.
PubMed ID: 17709345
DOI: 10.1093/nar/gkm617
PubMed ID: 17160021
Title: N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation.
PubMed ID: 17160021
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 22105363
Title: The kinase c-Src and the phosphatase TC45 coordinately regulate c-Fos tyrosine phosphorylation and c-Fos phospholipid synthesis activation capacity.
PubMed ID: 22105363
DOI: 10.1038/onc.2011.510
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 7816143
Title: Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
PubMed ID: 7816143
DOI: 10.1038/373257a0
Sequence Information:
- Length: 380
- Mass: 40695
- Checksum: 9E3B2969347C90C8
- Sequence:
MMFSGFNADY EASSSRCSSA SPAGDSLSYY HSPADSFSSM GSPVNAQDFC TDLAVSSANF IPTVTAISTS PDLQWLVQPA LVSSVAPSQT RAPHPFGVPA PSAGAYSRAG VVKTMTGGRA QSIGRRGKVE QLSPEEEEKR RIRRERNKMA AAKCRNRRRE LTDTLQAETD QLEDEKSALQ TEIANLLKEK EKLEFILAAH RPACKIPDDL GFPEEMSVAS LDLTGGLPEV ATPESEEAFT LPLLNDPEPK PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS FPSCAAAHRK GSSSNEPSSD SLSSPTLLAL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.