Details for: HLA DQB1
Gene ID: 3119
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: HLA DQB1
Ensembl ID: ENSG00000179344
Description: major histocompatibility complex, class II, DQ beta 1
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 88.08rCSI 65.76%PRS 91.11
-
CSI 75.86rCSI 63.82%PRS 91.4
-
CSI 72.98rCSI 62.59%PRS 85.83
-
CSI 63.32rCSI 62.53%PRS 91.84
-
CSI 62.09rCSI 53.98%PRS 88.56
-
CSI 60.03rCSI 55.12%PRS 86.87
-
CSI 59.6rCSI 44.28%PRS 89.57
-
CSI 56.82rCSI 39.67%PRS 82.64
-
CSI 56.81rCSI 68.62%PRS 86.75
-
CSI 54.19rCSI 82.76%PRS 89.9
-
CSI 52.77rCSI 44.05%PRS 79.99
-
CSI 50.21rCSI 72.73%PRS 91.25
-
CSI 48.7rCSI 61.22%PRS 88.27
-
CSI 45.9rCSI 70.49%PRS 87.63
-
CSI 44.34rCSI 34.16%PRS 82.13
-
CSI 42.42rCSI 52.27%PRS 83.66
-
CSI 42.17rCSI 30.27%PRS 91.18
-
CSI 39.87rCSI 53.34%PRS 86.75
-
CSI 38.38rCSI 63.21%PRS 83.18
-
CSI 37.97rCSI 83.58%PRS 83.08
-
CSI 34.27rCSI 31.61%PRS 80.84
-
CSI 29.99rCSI 30.38%PRS 92.33
-
CSI 27.63rCSI 61.7%PRS 86.25
-
CSI 27.59rCSI 26.54%PRS 92.28
-
CSI 24.78rCSI 45.08%PRS 86.37
-
CSI 24.53rCSI 32.14%PRS 89.51
-
CSI 21.84rCSI 32%PRS 86.59
-
CSI 20.59rCSI 21.49%PRS 78.71
-
CSI 20.5rCSI 32.86%PRS 90.04
-
CSI 19.99rCSI 20.71%PRS 83.64
-
CSI 19.9rCSI 65.14%PRS 93.87
-
CSI 19.24rCSI 32.87%PRS 93.37
-
CSI 19.21rCSI 24.11%PRS 87.87
-
CSI 19.18rCSI 57.19%PRS 89.11
-
CSI 18.75rCSI 68.15%PRS 92.96
-
CSI 18.2rCSI 37.76%PRS 76.14
-
CSI 18.18rCSI 40.8%PRS 90.89
-
CSI 17.88rCSI 32.31%PRS 84.69
-
CSI 17.4rCSI 14.41%PRS 81.82
-
CSI 15.49rCSI 19.82%PRS 89.2
-
CSI 15.45rCSI 10.27%PRS 82.13
-
CSI 15.36rCSI 34.85%PRS 80.04
-
CSI 14.74rCSI 12.91%PRS 86.52
-
CSI 14.72rCSI 10.23%PRS 90.09
-
CSI 13.14rCSI 73.93%PRS 92.24
-
CSI 13.09rCSI 17.88%PRS 79.23
-
CSI 13.04rCSI 60.25%PRS 91.01
-
CSI 12.74rCSI 29.13%PRS 80.11
-
CSI 12.61rCSI 15.71%PRS 88.13
-
CSI 12.4rCSI 11.3%PRS 90.68
-
CSI 11.88rCSI 17.92%PRS 84.52
-
CSI 11.28rCSI 17.5%PRS 83.59
-
CSI 11.23rCSI 42.77%PRS 70.45
-
CSI 11.19rCSI 18.12%PRS 74.4
-
CSI 10.86rCSI 15.89%PRS 84.07
-
CSI 10.84rCSI 8.14%PRS 84.98
-
CSI 10.47rCSI 9.89%PRS 78.03
-
CSI 10.15rCSI 9.77%PRS 78.72
-
CSI 9.98rCSI 19.03%PRS 88.84
-
CSI 9.82rCSI 7.61%PRS 83.04
-
CSI 9.82rCSI 10.05%PRS 87.05
-
CSI 9.59rCSI 7.3%PRS 91.16
-
CSI 9.35rCSI 7.56%PRS 81.63
-
CSI 9.24rCSI 7.27%PRS 84.32
-
CSI 8.93rCSI 6.95%PRS 92.36
-
CSI 8.92rCSI 7.72%PRS 83.31
-
CSI 8.72rCSI 23.79%PRS 87.24
-
CSI 8.64rCSI 10.02%PRS 83.27
-
CSI 8.54rCSI 11.61%PRS 87.74
-
CSI 8.14rCSI 13.12%PRS 78.56
-
CSI 8.06rCSI 11.8%PRS 73.89
-
CSI 7.73rCSI 9.06%PRS 91.94
-
CSI 7.65rCSI 15.8%PRS 76.67
-
CSI 7.4rCSI 33.28%PRS 94.56
-
CSI 7.26rCSI 18.93%PRS 80.46
-
CSI 7.26rCSI 43.93%PRS 90.23
-
CSI 7.21rCSI 5.39%PRS 91.3
-
CSI 6.66rCSI 7.98%PRS 89.11
-
CSI 6.28rCSI 5.52%PRS 84.28
-
CSI 6.1rCSI 8.44%PRS 76.74
-
CSI 6.07rCSI 24.45%PRS 80.95
-
CSI 5.9rCSI 9.01%PRS 79.64
-
CSI 5.79rCSI 5.78%PRS 73.23
-
CSI 5.64rCSI 12.86%PRS 73.25
-
CSI 5.58rCSI 6.66%PRS 93.16
-
CSI 5.57rCSI 5.47%PRS 91.74
-
CSI 5.51rCSI 34.01%PRS 88.41
-
CSI 5.44rCSI 4.51%PRS 80.05
-
CSI 5.32rCSI 15.19%PRS 84.92
-
CSI 5.3rCSI 9.57%PRS 93.74
-
CSI 5.22rCSI 7.65%PRS 88.32
-
CSI 5.13rCSI 8.19%PRS 83.09
-
CSI 5.03rCSI 14.43%PRS 94.38
-
CSI 4.95rCSI 53.87%PRS 89.48
-
CSI 4.94rCSI 17%PRS 90.72
-
CSI 4.74rCSI 5.49%PRS 71.66
-
CSI 4.69rCSI 5.37%PRS 89.68
-
CSI 4.52rCSI 6.52%PRS 86.24
-
CSI 4.38rCSI 3.67%PRS 82.41
-
CSI 4.33rCSI 3.81%PRS 68.57
-
CSI 0.4rCSI 4.4%PRS 87.6%
-
CSI 0.6rCSI 3.2%PRS 83.2%
-
CSI 0.6rCSI 3.5%PRS 85.3%
-
CSI 0.8rCSI 6.3%PRS 88.2%
-
CSI 0.9rCSI 4.4%PRS 90.4%
-
CSI 0.9rCSI 1.8%PRS 82.3%
-
CSI 1.1rCSI 26.5%PRS 88.0%
-
CSI 1.2rCSI 4.2%PRS 87.3%
-
CSI 1.5rCSI 6.5%PRS 86.4%
-
CSI 1.5rCSI 11.1%PRS 87.7%
-
CSI 1.5rCSI 2.1%PRS 78.8%
-
CSI 1.6rCSI 31.0%PRS 91.3%
-
CSI 1.7rCSI 1.4%PRS 94.7%
-
CSI 1.8rCSI 6.5%PRS 93.6%
-
CSI 1.8rCSI 35.6%PRS 87.5%
-
CSI 2.0rCSI 52.5%PRS 94.2%
-
CSI 2.2rCSI 10.2%PRS 90.3%
-
CSI 2.7rCSI 5.2%PRS 92.4%
-
CSI 2.8rCSI 11.0%PRS 87.5%
-
CSI 2.8rCSI 4.0%PRS 85.1%
-
CSI 2.8rCSI 5.4%PRS 95.0%
-
CSI 2.9rCSI 5.1%PRS 87.9%
-
CSI 3.0rCSI 3.4%PRS 91.6%
-
CSI 3.1rCSI 13.3%PRS 84.9%
-
CSI 3.1rCSI 3.3%PRS 84.5%
-
CSI 3.1rCSI 6.7%PRS 86.5%
-
CSI 3.1rCSI 65.8%PRS 93.8%
-
CSI 3.1rCSI 4.0%PRS 82.7%
-
CSI 3.2rCSI 14.3%PRS 87.4%
-
CSI 3.2rCSI 54.6%PRS 89.4%
-
CSI 3.2rCSI 8.0%PRS 79.0%
-
CSI 3.6rCSI 8.7%PRS 91.7%
-
CSI 3.7rCSI 4.5%PRS 60.6%
-
CSI 3.8rCSI 9.9%PRS 94.2%
-
CSI 4.0rCSI 6.8%PRS 85.5%
-
CSI 4.0rCSI 3.6%PRS 77.6%
-
CSI 4.3rCSI 10.7%PRS 92.4%
-
CSI 4.3rCSI 3.8%PRS 68.6%
-
CSI 4.4rCSI 3.7%PRS 82.4%
-
CSI 4.5rCSI 6.5%PRS 86.2%
-
CSI 4.7rCSI 5.4%PRS 89.7%
-
CSI 4.7rCSI 5.5%PRS 71.7%
-
CSI 4.9rCSI 17.0%PRS 90.7%
-
CSI 5.0rCSI 53.9%PRS 89.5%
-
CSI 5.0rCSI 14.4%PRS 94.4%
-
CSI 5.1rCSI 8.2%PRS 83.1%
-
CSI 5.2rCSI 7.7%PRS 88.3%
-
CSI 5.3rCSI 9.6%PRS 93.7%
-
CSI 5.3rCSI 15.2%PRS 84.9%
-
CSI 5.4rCSI 4.5%PRS 80.1%
-
CSI 5.5rCSI 34.0%PRS 88.4%
-
CSI 5.6rCSI 5.5%PRS 91.7%
-
CSI 5.6rCSI 6.7%PRS 93.2%
-
CSI 5.6rCSI 12.9%PRS 73.3%
-
CSI 5.8rCSI 5.8%PRS 73.2%
-
CSI 5.9rCSI 9.0%PRS 79.6%
-
CSI 6.1rCSI 24.5%PRS 81.0%
-
CSI 6.1rCSI 8.4%PRS 76.7%
-
CSI 6.3rCSI 5.5%PRS 84.3%
-
CSI 6.7rCSI 8.0%PRS 89.1%
-
CSI 7.2rCSI 5.4%PRS 91.3%
-
CSI 7.3rCSI 43.9%PRS 90.2%
-
CSI 7.3rCSI 18.9%PRS 80.5%
-
CSI 7.4rCSI 33.3%PRS 94.6%
-
CSI 7.7rCSI 15.8%PRS 76.7%
-
CSI 7.7rCSI 9.1%PRS 91.9%
-
CSI 8.1rCSI 11.8%PRS 73.9%
-
CSI 8.1rCSI 13.1%PRS 78.6%
-
CSI 8.5rCSI 11.6%PRS 87.7%
-
CSI 8.6rCSI 10.0%PRS 83.3%
-
CSI 8.7rCSI 23.8%PRS 87.2%
-
CSI 8.9rCSI 7.7%PRS 83.3%
-
CSI 8.9rCSI 7.0%PRS 92.4%
-
CSI 9.2rCSI 7.3%PRS 84.3%
-
CSI 9.4rCSI 7.6%PRS 81.6%
-
CSI 9.6rCSI 7.3%PRS 91.2%
-
CSI 9.8rCSI 10.1%PRS 87.1%
-
CSI 9.8rCSI 7.6%PRS 83.0%
-
CSI 10.0rCSI 19.0%PRS 88.8%
-
CSI 10.2rCSI 9.8%PRS 78.7%
-
CSI 10.5rCSI 9.9%PRS 78.0%
-
CSI 10.8rCSI 8.1%PRS 85.0%
-
CSI 10.9rCSI 15.9%PRS 84.1%
-
CSI 11.2rCSI 18.1%PRS 74.4%
-
CSI 11.2rCSI 42.8%PRS 70.5%
-
CSI 11.3rCSI 17.5%PRS 83.6%
-
CSI 11.9rCSI 17.9%PRS 84.5%
-
CSI 12.4rCSI 11.3%PRS 90.7%
-
CSI 12.6rCSI 15.7%PRS 88.1%
-
CSI 12.7rCSI 29.1%PRS 80.1%
-
CSI 13.0rCSI 60.3%PRS 91.0%
-
CSI 13.1rCSI 17.9%PRS 79.2%
-
CSI 13.1rCSI 73.9%PRS 92.2%
-
CSI 14.7rCSI 10.2%PRS 90.1%
-
CSI 14.7rCSI 12.9%PRS 86.5%
-
CSI 15.4rCSI 34.9%PRS 80.0%
-
CSI 15.5rCSI 10.3%PRS 82.1%
-
CSI 15.5rCSI 19.8%PRS 89.2%
-
CSI 17.4rCSI 14.4%PRS 81.8%
-
CSI 17.9rCSI 32.3%PRS 84.7%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2267932439
Symbol: DQB1_HUMAN
Name: HLA class II histocompatibility antigen, DQ beta 1 chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 6415003
Title: Molecular analysis of human class II transplantation antigens and their genes.
PubMed ID: 6415003
PubMed ID: 6954511
Title: Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.
PubMed ID: 6954511
PubMed ID: 6316358
Title: Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene.
PubMed ID: 6316358
PubMed ID: 6206493
Title: Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.
PubMed ID: 6206493
PubMed ID: 2998758
Title: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.
PubMed ID: 2998758
PubMed ID: 2888727
Title: Allelic forms of the alpha- and beta-chain genes encoding DQw1-positive heterodimers.
PubMed ID: 2888727
DOI: 10.1007/bf00346523
PubMed ID: 3036828
Title: Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes.
PubMed ID: 3036828
PubMed ID: 3584986
Title: Complete sequence of the HLA DQ alpha and DQ beta cDNA from a DR5/DQw3 cell line.
PubMed ID: 3584986
PubMed ID: 3259543
PubMed ID: 2050393
Title: Full length beta chain cDNAs of DQw9 and DQw8 molecules encode proteins that differ only at amino acid 57.
PubMed ID: 2050393
DOI: 10.1007/bf00216702
PubMed ID: 8988543
Title: Complete coding region of the new HLA-DQB1*0612 allele, obtained by RT-PCR.
PubMed ID: 8988543
PubMed ID: 9271631
Title: HLA class II haplotype and sequence analysis support a role for DQ in narcolepsy.
PubMed ID: 9271631
PubMed ID: 16140993
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2925231
Title: Sequence analysis of HLA class II domains: characterization of the DQw3 family of DQB genes.
PubMed ID: 2925231
DOI: 10.1007/bf00373644
PubMed ID: 2494138
Title: No difference in the nucleotide sequence of the DQ beta beta 1 domain between narcoleptic and healthy individuals with DR2,Dw2.
PubMed ID: 2494138
PubMed ID: 2777341
Title: Complete sequences of DQA1 and DQB1 cDNA clones corresponding to the DQw4 specificity.
PubMed ID: 2777341
DOI: 10.1007/bf02421214
PubMed ID: 8929711
Title: Different contribution of HLA-DR and -DQ genes in susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM).
PubMed ID: 8929711
PubMed ID: 11098940
Title: Identification by sequencing based typing and complete coding region analysis of three new HLA class II alleles: DRB3*0210, DRB3*0211 and DQB1*0310.
PubMed ID: 11098940
PubMed ID: 7928445
Title: HLA-DQB1*0305 and -DQB1*0304 alleles among Sardinians. Evolutionary and practical implications for oligotyping.
PubMed ID: 7928445
PubMed ID: 6576979
Title: Primary structure of human class II histocompatibility antigens 3rd communication. Amino acid sequence comparison between DR and DC subclass antigens derived from a lymphoblastoid B cell line homozygous at the HLA loci (HLA-A3,3; B7,7; Dw2,2; DR2,2: MT1,1; Dc1,1: MB1,1).
PubMed ID: 6576979
PubMed ID: 2212675
Title: Two divergent routes of evolution gave rise to the DRw13 haplotypes.
PubMed ID: 2212675
PubMed ID: 3020127
Title: Analysis of DR-beta and DQ-beta chain cDNA clones from a DR7 haplotype.
PubMed ID: 3020127
PubMed ID: 17868257
Title: Identification of a novel allele HLA-DQB1*0622.
PubMed ID: 17868257
PubMed ID: 2886427
Title: Structural and functional variability among DQ beta alleles of DR2 subtypes.
PubMed ID: 2886427
DOI: 10.1007/bf00345459
PubMed ID: 9174147
Title: A novel allele, DQB1*0307, in a West African family.
PubMed ID: 9174147
PubMed ID: 11782280
Title: Identification of a novel HLA-DQB1*06 allele, DQB1*0618.
PubMed ID: 11782280
PubMed ID: 9458130
Title: Identification of a new DQB1*0613 allele in a family.
PubMed ID: 9458130
PubMed ID: 17559588
Title: HLA-DQB1*0319, a novel HLA-DQB1 allele, shows strong haplotype association to HLA-DRB1*1102.
PubMed ID: 17559588
PubMed ID: 18331527
Title: HLA-DQB1*0634, a novel DQB1 allele found by high-resolution HLA typing of a sibling pair for potential bone marrow transplantation.
PubMed ID: 18331527
PubMed ID: 18588576
Title: Novel alleles at the HLA-DRB1 and -DQB1 loci.
PubMed ID: 18588576
PubMed ID: 19254265
Title: Sequence-based HLA high-resolution retyping of a bone marrow donor/recipient pair reveals the novel HLA allele DQB1*0322.
PubMed ID: 19254265
PubMed ID: 19493242
Title: DQB1*0323 is the result of a gene conversion event between a DQB1*06 and a DQB1*030303 allele.
PubMed ID: 19493242
PubMed ID: 8896183
Title: Characterization of a new DQB1 allele (DQB1*0610) which differs from DQB1*0602 at the highly polymorphic 57-codon.
PubMed ID: 8896183
PubMed ID: 8988541
Title: A new HLA-DQB1*0306 allele sharing motifs from DQB1*03032 and DQB1*04 sequences.
PubMed ID: 8988541
PubMed ID: 15361133
Title: Identification of two novel HLA class II alleles, DQB1*0311 and DQB1*0620.
PubMed ID: 15361133
PubMed ID: 15853909
Title: Identification of a novel HLA-DQB1 allele, DQB1*0314, by sequence-based typing in the Korean population.
PubMed ID: 15853909
PubMed ID: 17212715
Title: A novel HLA-DQB1*06 allele, DQB1*0628, found through routine sequence-based HLA typing and confirmation of DQB1*060302.
PubMed ID: 17212715
PubMed ID: 17999653
Title: Identification of a novel HLA-DQB1 allele, HLA-DQB1*0632.
PubMed ID: 17999653
PubMed ID: 19392794
Title: Two new HLA-DQB alleles routinely identified by sequence-based typing: DQB1*030103 and DQB1*0505.
PubMed ID: 19392794
PubMed ID: 10323344
Title: Identification of a novel DQB1 allele DBQ1*0616.
PubMed ID: 10323344
PubMed ID: 9802612
Title: A novel DRB3 allele (DRB3*0208), a new allelic variant of DRB1*1502 (DRB1*15023) and two new DQB1 (DQB1*03012 and DQB1*0614) alleles.
PubMed ID: 9802612
PubMed ID: 8896171
Title: Strategy for distinguishing a new DQB1 allele (DQB1*0611) from the closely related DQB1*0602 allele via sequence specific PCR or direct DNA sequencing.
PubMed ID: 8896171
PubMed ID: 16441489
Title: HLA-DRB1*0826 and HLA-DQB1*0627, two novel class II alleles identified in blood stem cell donors of Caucasian origin.
PubMed ID: 16441489
PubMed ID: 1440562
Title: Two novel HLA-DQB1*06 alleles reveal additional heterogeneity of HLA-DQw1.
PubMed ID: 1440562
PubMed ID: 2308943
Title: Allelic diversification at the class II DQB locus of the mammalian major histocompatibility complex.
PubMed ID: 2308943
PubMed ID: 2010218
Title: Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA.
PubMed ID: 2010218
DOI: 10.1007/bf01719235
PubMed ID: 6952552
Title: Evolutionary relationship between HLA-DR antigen beta-chains, HLA-A, B, C antigen subunits and immunoglobulin chains.
PubMed ID: 6952552
PubMed ID: 18565458
Title: CSF hypocretin-1 assessment in sleep and neurological disorders.
PubMed ID: 18565458
PubMed ID: 8598037
Title: Invariant chain structure and MHC class II function.
PubMed ID: 8598037
PubMed ID: 11684289
Title: Presentation of antigens by MHC class II molecules: getting the most out of them.
PubMed ID: 11684289
PubMed ID: 18046453
Title: MHC class II molecules on the move for successful antigen presentation.
PubMed ID: 18046453
PubMed ID: 17241953
Title: Autophagy in MHC class II presentation: sampling from within.
PubMed ID: 17241953
PubMed ID: 19092054
PubMed ID: 19533806
Title: CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract.
PubMed ID: 19533806
DOI: 10.3748/wjg.15.2855
PubMed ID: 11376336
Title: Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.
PubMed ID: 11376336
DOI: 10.1038/88694
PubMed ID: 14769912
Title: Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy.
PubMed ID: 14769912
PubMed ID: 15020763
Title: Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease.
PubMed ID: 15020763
PubMed ID: 17629515
Title: A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease.
PubMed ID: 17629515
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 261
- Mass: 29991
- Checksum: 79B1E571A628CF96
- Sequence:
MSWKKALRIP GGLRAATVTL MLAMLSTPVA EGRDSPEDFV YQFKAMCYFT NGTERVRYVT RYIYNREEYA RFDSDVEVYR AVTPLGPPDA EYWNSQKEVL ERTRAELDTV CRHNYQLELR TTLQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPAQIK VRWFRNDQEE TTGVVSTPLI RNGDWTFQIL VMLEMTPQHG DVYTCHVEHP SLQNPITVEW RAQSESAQSK MLSGIGGFVL GLIFLGLGLI IHHRSQKGLL H
Genular Protein ID: 3345764557
Symbol: Q5Y7D6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 16140993
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23714642
Title: Phase-defined complete sequencing of the HLA genes by next-generation sequencing.
PubMed ID: 23714642
PubMed ID: 28547825
Title: Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles.
PubMed ID: 28547825
DOI: 10.1111/tan.13057
PubMed ID: 30337930
Title: Reference Grade Characterization of Polymorphisms in Full-Length HLA Class I and II Genes With Short-Read Sequencing on the ION PGM System and Long-Reads Generated by Single Molecule, Real-Time Sequencing on the PacBio Platform.
PubMed ID: 30337930
PubMed ID: 29327506
Title: Next generation sequencing characterizes the extent of HLA diversity in an Argentinian registry population.
PubMed ID: 29327506
DOI: .1111/tan.13210
PubMed ID: 31981322
Title: Characterization of two novel HLA-DQB1*06:02:01 variants, identified in Brazilian individuals.
PubMed ID: 31981322
Sequence Information:
- Length: 261
- Mass: 29791
- Checksum: 955BF0E22AA4BD79
- Sequence:
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPEDFV FQFKGMCYFT NGTERVRLVT RYIYNREEYA RFDSDVGVYR AVTPQGRPDA EYWNSQKEVL EGTRAELDTV CRHNYEVAFR GILQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPGQIK VRWFRNDQEE TAGVVSTPLI RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RAQSESAQSK MLSGVGGFVL GLIFLGLGLI IRQRSQKGLL H
Genular Protein ID: 773728169
Symbol: Q5Y7D3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16140993
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22362761
Title: Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule.
PubMed ID: 22362761
PubMed ID: 24777060
Title: T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
PubMed ID: 24777060
DOI: 10.1038/nsmb.2817
PubMed ID: 28364043
Title: Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
PubMed ID: 28364043
PubMed ID: 30337930
Title: Reference Grade Characterization of Polymorphisms in Full-Length HLA Class I and II Genes With Short-Read Sequencing on the ION PGM System and Long-Reads Generated by Single Molecule, Real-Time Sequencing on the PacBio Platform.
PubMed ID: 30337930
PubMed ID: 34417258
Title: A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
PubMed ID: 34417258
PubMed ID: 35065967
Title: Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
PubMed ID: 35065967
Sequence Information:
- Length: 261
- Mass: 29733
- Checksum: 8957ACD3E93DD105
- Sequence:
MSWKKALRIP GGLRAATVTL MLSMLSTPVA EGRDSPEDFV YQFKGMCYFT NGTERVRLVS RSIYNREEIV RFDSDVGEFR AVTLLGLPAA EYWNSQKDIL ERKRAAVDRV CRHNYQLELR TTLQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPAQIK VRWFRNDQEE TAGVVSTPLI RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RAQSESAQSK MLSGIGGFVL GLIFLGLGLI IHHRSQKGLL H
Genular Protein ID: 2669682166
Symbol: Q5SU54_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 31748512
Title: In vivo clonal expansion and phenotypes of hypocretin-specific CD4<sup>+</sup> T cells in narcolepsy patients and controls.
PubMed ID: 31748512
Sequence Information:
- Length: 269
- Mass: 30493
- Checksum: 8406DCC525CF48CA
- Sequence:
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPEDFV FQFKGMCYFT NGTERVRLVT RYIYNREEYA RFDSDVGVYR AVTPQGRPDA EYWNSQKEVL EGTRAELDTV CRHNYEVAFR GILQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPGQIK VRWFRNDQEE TAGVVSTPLI RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RAQSESAQSK MLSGVGGFVL GLIFLGLGLI IRQRSQKGPQ GPPPAGLLH
Genular Protein ID: 1462464936
Symbol: Q5Y7A9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16140993
PubMed ID: 23714642
Title: Phase-defined complete sequencing of the HLA genes by next-generation sequencing.
PubMed ID: 23714642
PubMed ID: 28547825
Title: Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles.
PubMed ID: 28547825
DOI: 10.1111/tan.13057
PubMed ID: 30337930
Title: Reference Grade Characterization of Polymorphisms in Full-Length HLA Class I and II Genes With Short-Read Sequencing on the ION PGM System and Long-Reads Generated by Single Molecule, Real-Time Sequencing on the PacBio Platform.
PubMed ID: 30337930
Sequence Information:
- Length: 261
- Mass: 29781
- Checksum: 321527DC13AD1046
- Sequence:
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPEDFV YQFKGMCYFT NGTERVRLVT RHIYNREEYA RFDSDVGVYR AVTPQGRPDA EYWNSQKEVL EGTRAELDTV CRHNYEVAFR GILQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPGQIK VRWFRNDQEE TAGVVSTPLI RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RAQSESAQSK MLSGVGGFVL GLIFLGLGLI IRQRSQKGLL H